Faraz Quazi, Stepan Lenevich, Robert S Molday. Nat Commun 2012
Times Cited: 153
Times Cited: 153
Times Cited
Times Co-cited
Similarity
A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy.
R Allikmets, N Singh, H Sun, N F Shroyer, A Hutchinson, A Chidambaram, B Gerrard, L Baird, D Stauffer, A Peiffer,[...]. Nat Genet 1997
R Allikmets, N Singh, H Sun, N F Shroyer, A Hutchinson, A Chidambaram, B Gerrard, L Baird, D Stauffer, A Peiffer,[...]. Nat Genet 1997
35
Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice.
J Weng, N L Mata, S M Azarian, R T Tzekov, D G Birch, G H Travis. Cell 1999
J Weng, N L Mata, S M Azarian, R T Tzekov, D G Birch, G H Travis. Cell 1999
30
ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal.
Faraz Quazi, Robert S Molday. Proc Natl Acad Sci U S A 2014
Faraz Quazi, Robert S Molday. Proc Natl Acad Sci U S A 2014
32
Autosomal recessive retinitis pigmentosa and cone-rod dystrophy caused by splice site mutations in the Stargardt's disease gene ABCR.
F P Cremers, D J van de Pol, M van Driel, A I den Hollander, F J van Haren, N V Knoers, N Tijmes, A A Bergen, K Rohrschneider, A Blankenagel,[...]. Hum Mol Genet 1998
F P Cremers, D J van de Pol, M van Driel, A I den Hollander, F J van Haren, N V Knoers, N Tijmes, A A Bergen, K Rohrschneider, A Blankenagel,[...]. Hum Mol Genet 1998
21
Structure of the Human Lipid Exporter ABCA1.
Hongwu Qian, Xin Zhao, Pingping Cao, Jianlin Lei, Nieng Yan, Xin Gong. Cell 2017
Hongwu Qian, Xin Zhao, Pingping Cao, Jianlin Lei, Nieng Yan, Xin Gong. Cell 2017
20
Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.
Faraz Quazi, Robert S Molday. J Biol Chem 2013
Faraz Quazi, Robert S Molday. J Biol Chem 2013
19
Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options.
Preena Tanna, Rupert W Strauss, Kaoru Fujinami, Michel Michaelides. Br J Ophthalmol 2017
Preena Tanna, Rupert W Strauss, Kaoru Fujinami, Michel Michaelides. Br J Ophthalmol 2017
19
Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration.
N L Mata, J Weng, G H Travis. Proc Natl Acad Sci U S A 2000
N L Mata, J Weng, G H Travis. Proc Natl Acad Sci U S A 2000
18
N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).
Seelochan Beharry, Ming Zhong, Robert S Molday. J Biol Chem 2004
Seelochan Beharry, Ming Zhong, Robert S Molday. J Biol Chem 2004
17
The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily.
M Illing, L L Molday, R S Molday. J Biol Chem 1997
M Illing, L L Molday, R S Molday. J Biol Chem 1997
17
Mutations in the ABCA4 (ABCR) gene are the major cause of autosomal recessive cone-rod dystrophy.
A Maugeri, B J Klevering, K Rohrschneider, A Blankenagel, H G Brunner, A F Deutman, C B Hoyng, F P Cremers. Am J Hum Genet 2000
A Maugeri, B J Klevering, K Rohrschneider, A Blankenagel, H G Brunner, A F Deutman, C B Hoyng, F P Cremers. Am J Hum Genet 2000
16
Crystal structure of the human sterol transporter ABCG5/ABCG8.
Jyh-Yeuan Lee, Lisa N Kinch, Dominika M Borek, Jin Wang, Junmei Wang, Ina L Urbatsch, Xiao-Song Xie, Nikolai V Grishin, Jonathan C Cohen, Zbyszek Otwinowski,[...]. Nature 2016
Jyh-Yeuan Lee, Lisa N Kinch, Dominika M Borek, Jin Wang, Junmei Wang, Ina L Urbatsch, Xiao-Song Xie, Nikolai V Grishin, Jonathan C Cohen, Zbyszek Otwinowski,[...]. Nature 2016
16
ABCR expression in foveal cone photoreceptors and its role in Stargardt macular dystrophy.
L L Molday, A R Rabin, R S Molday. Nat Genet 2000
L L Molday, A R Rabin, R S Molday. Nat Genet 2000
16
15
Molecular organization and ATP-induced conformational changes of ABCA4, the photoreceptor-specific ABC transporter.
Yaroslav Tsybovsky, Tivadar Orban, Robert S Molday, Derek Taylor, Krzysztof Palczewski. Structure 2013
Yaroslav Tsybovsky, Tivadar Orban, Robert S Molday, Derek Taylor, Krzysztof Palczewski. Structure 2013
34
Retinopathy in mice induced by disrupted all-trans-retinal clearance.
Akiko Maeda, Tadao Maeda, Marcin Golczak, Krzysztof Palczewski. J Biol Chem 2008
Akiko Maeda, Tadao Maeda, Marcin Golczak, Krzysztof Palczewski. J Biol Chem 2008
15
Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Camilo Perez, Sabina Gerber, Jérémy Boilevin, Monika Bucher, Tamis Darbre, Markus Aebi, Jean-Louis Reymond, Kaspar P Locher. Nature 2015
Camilo Perez, Sabina Gerber, Jérémy Boilevin, Monika Bucher, Tamis Darbre, Markus Aebi, Jean-Louis Reymond, Kaspar P Locher. Nature 2015
14
N965S is a common ABCA4 variant in Stargardt-related retinopathies in the Danish population.
Thomas Rosenberg, Flemming Klie, Peter Garred, Marianne Schwartz. Mol Vis 2007
Thomas Rosenberg, Flemming Klie, Peter Garred, Marianne Schwartz. Mol Vis 2007
29
The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration.
Robert S Molday, Ming Zhong, Faraz Quazi. Biochim Biophys Acta 2009
Robert S Molday, Ming Zhong, Faraz Quazi. Biochim Biophys Acta 2009
14
Stargardt's ABCR is localized to the disc membrane of retinal rod outer segments.
H Sun, J Nathans. Nat Genet 1997
H Sun, J Nathans. Nat Genet 1997
14
Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.
Ning Zhang, Yaroslav Tsybovsky, Alexander V Kolesnikov, Malgorzata Rozanowska, Malgorzata Swider, Sharon B Schwartz, Edwin M Stone, Grazyna Palczewska, Akiko Maeda, Vladimir J Kefalov,[...]. Hum Mol Genet 2015
Ning Zhang, Yaroslav Tsybovsky, Alexander V Kolesnikov, Malgorzata Rozanowska, Malgorzata Swider, Sharon B Schwartz, Edwin M Stone, Grazyna Palczewska, Akiko Maeda, Vladimir J Kefalov,[...]. Hum Mol Genet 2015
26
Frequent hypomorphic alleles account for a significant fraction of ABCA4 disease and distinguish it from age-related macular degeneration.
Jana Zernant, Winston Lee, Frederick T Collison, Gerald A Fishman, Yuri V Sergeev, Kaspar Schuerch, Janet R Sparrow, Stephen H Tsang, Rando Allikmets. J Med Genet 2017
Jana Zernant, Winston Lee, Frederick T Collison, Gerald A Fishman, Yuri V Sergeev, Kaspar Schuerch, Janet R Sparrow, Stephen H Tsang, Rando Allikmets. J Med Genet 2017
15
Insights into the Molecular Properties of ABCA4 and Its Role in the Visual Cycle and Stargardt Disease.
Robert S Molday. Prog Mol Biol Transl Sci 2015
Robert S Molday. Prog Mol Biol Transl Sci 2015
31
A comprehensive survey of sequence variation in the ABCA4 (ABCR) gene in Stargardt disease and age-related macular degeneration.
A Rivera, K White, H Stöhr, K Steiner, N Hemmrich, T Grimm, B Jurklies, B Lorenz, H P Scholl, E Apfelstedt-Sylla,[...]. Am J Hum Genet 2000
A Rivera, K White, H Stöhr, K Steiner, N Hemmrich, T Grimm, B Jurklies, B Lorenz, H P Scholl, E Apfelstedt-Sylla,[...]. Am J Hum Genet 2000
13
Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease.
H Sun, R S Molday, J Nathans. J Biol Chem 1999
H Sun, R S Molday, J Nathans. J Biol Chem 1999
13
Correlating the Expression and Functional Activity of ABCA4 Disease Variants With the Phenotype of Patients With Stargardt Disease.
Fabian Garces, Kailun Jiang, Laurie L Molday, Heidi Stöhr, Bernhard H Weber, Christopher J Lyons, David Maberley, Robert S Molday. Invest Ophthalmol Vis Sci 2018
Fabian Garces, Kailun Jiang, Laurie L Molday, Heidi Stöhr, Bernhard H Weber, Christopher J Lyons, David Maberley, Robert S Molday. Invest Ophthalmol Vis Sci 2018
43
Clinical and genetic characteristics of late-onset Stargardt's disease.
Sarah C Westeneng-van Haaften, Camiel J F Boon, Frans P M Cremers, Lies H Hoefsloot, Anneke I den Hollander, Carel B Hoyng. Ophthalmology 2012
Sarah C Westeneng-van Haaften, Camiel J F Boon, Frans P M Cremers, Lies H Hoefsloot, Anneke I den Hollander, Carel B Hoyng. Ophthalmology 2012
12
Genotype/Phenotype analysis of a photoreceptor-specific ATP-binding cassette transporter gene, ABCR, in Stargardt disease.
R A Lewis, N F Shroyer, N Singh, R Allikmets, A Hutchinson, Y Li, J R Lupski, M Leppert, M Dean. Am J Hum Genet 1999
R A Lewis, N F Shroyer, N Singh, R Allikmets, A Hutchinson, Y Li, J R Lupski, M Leppert, M Dean. Am J Hum Genet 1999
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Biochemical defects in ABCR protein variants associated with human retinopathies.
H Sun, P M Smallwood, J Nathans. Nat Genet 2000
H Sun, P M Smallwood, J Nathans. Nat Genet 2000
12
Retinitis pigmentosa caused by a homozygous mutation in the Stargardt disease gene ABCR.
A Martínez-Mir, E Paloma, R Allikmets, C Ayuso, T del Rio, M Dean, L Vilageliu, R Gonzàlez-Duarte, S Balcells. Nat Genet 1998
A Martínez-Mir, E Paloma, R Allikmets, C Ayuso, T del Rio, M Dean, L Vilageliu, R Gonzàlez-Duarte, S Balcells. Nat Genet 1998
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RPE lipofuscin and its role in retinal pathobiology.
Janet R Sparrow, Mike Boulton. Exp Eye Res 2005
Janet R Sparrow, Mike Boulton. Exp Eye Res 2005
12
Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: identification of N-linked glycosylation sites.
S Bungert, L L Molday, R S Molday. J Biol Chem 2001
S Bungert, L L Molday, R S Molday. J Biol Chem 2001
12
In Silico Functional Meta-Analysis of 5,962 ABCA4 Variants in 3,928 Retinal Dystrophy Cases.
Stéphanie S Cornelis, Nathalie M Bax, Jana Zernant, Rando Allikmets, Lars G Fritsche, Johan T den Dunnen, Muhammad Ajmal, Carel B Hoyng, Frans P M Cremers. Hum Mutat 2017
Stéphanie S Cornelis, Nathalie M Bax, Jana Zernant, Rando Allikmets, Lars G Fritsche, Johan T den Dunnen, Muhammad Ajmal, Carel B Hoyng, Frans P M Cremers. Hum Mutat 2017
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Clinical spectrum, genetic complexity and therapeutic approaches for retinal disease caused by ABCA4 mutations.
Frans P M Cremers, Winston Lee, Rob W J Collin, Rando Allikmets. Prog Retin Eye Res 2020
Frans P M Cremers, Winston Lee, Rob W J Collin, Rando Allikmets. Prog Retin Eye Res 2020
17
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer.
Paul C Smith, Nathan Karpowich, Linda Millen, Jonathan E Moody, Jane Rosen, Philip J Thomas, John F Hunt. Mol Cell 2002
Paul C Smith, Nathan Karpowich, Linda Millen, Jonathan E Moody, Jane Rosen, Philip J Thomas, John F Hunt. Mol Cell 2002
11
The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.
Yaroslav Tsybovsky, Robert S Molday, Krzysztof Palczewski. Adv Exp Med Biol 2010
Yaroslav Tsybovsky, Robert S Molday, Krzysztof Palczewski. Adv Exp Med Biol 2010
11
Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol.
A Rattner, P M Smallwood, J Nathans. J Biol Chem 2000
A Rattner, P M Smallwood, J Nathans. J Biol Chem 2000
11
Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration.
R Allikmets, N F Shroyer, N Singh, J M Seddon, R A Lewis, P S Bernstein, A Peiffer, N A Zabriskie, Y Li, A Hutchinson,[...]. Science 1997
R Allikmets, N F Shroyer, N Singh, J M Seddon, R A Lewis, P S Bernstein, A Peiffer, N A Zabriskie, Y Li, A Hutchinson,[...]. Science 1997
11
Late-onset Stargardt disease is associated with missense mutations that map outside known functional regions of ABCR (ABCA4).
A N Yatsenko, N F Shroyer, R A Lewis, J R Lupski. Hum Genet 2001
A N Yatsenko, N F Shroyer, R A Lewis, J R Lupski. Hum Genet 2001
11
The 2588G-->C mutation in the ABCR gene is a mild frequent founder mutation in the Western European population and allows the classification of ABCR mutations in patients with Stargardt disease.
A Maugeri, M A van Driel, D J van de Pol, B J Klevering, F J van Haren, N Tijmes, A A Bergen, K Rohrschneider, A Blankenagel, A J Pinckers,[...]. Am J Hum Genet 1999
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11
The effect of lipid environment and retinoids on the ATPase activity of ABCR, the photoreceptor ABC transporter responsible for Stargardt macular dystrophy.
J Ahn, J T Wong, R S Molday. J Biol Chem 2000
J Ahn, J T Wong, R S Molday. J Biol Chem 2000
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Screening of ABCA4 Gene in a Chinese Cohort With Stargardt Disease or Cone-Rod Dystrophy With a Report on 85 Novel Mutations.
Feng Jiang, Zhe Pan, Ke Xu, Lu Tian, Yue Xie, Xiaohui Zhang, Jieqiong Chen, Bing Dong, Yang Li. Invest Ophthalmol Vis Sci 2016
Feng Jiang, Zhe Pan, Ke Xu, Lu Tian, Yue Xie, Xiaohui Zhang, Jieqiong Chen, Bing Dong, Yang Li. Invest Ophthalmol Vis Sci 2016
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Phenotypic subtypes of Stargardt macular dystrophy-fundus flavimaculatus.
N Lois, G E Holder, C Bunce, F W Fitzke, A C Bird. Arch Ophthalmol 2001
N Lois, G E Holder, C Bunce, F W Fitzke, A C Bird. Arch Ophthalmol 2001
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Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization.
Peter Charbel Issa, Alun R Barnard, Philipp Herrmann, Ilyas Washington, Robert E MacLaren. Proc Natl Acad Sci U S A 2015
Peter Charbel Issa, Alun R Barnard, Philipp Herrmann, Ilyas Washington, Robert E MacLaren. Proc Natl Acad Sci U S A 2015
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Analysis of the ABCA4 genomic locus in Stargardt disease.
Jana Zernant, Yajing Angela Xie, Carmen Ayuso, Rosa Riveiro-Alvarez, Miguel-Angel Lopez-Martinez, Francesca Simonelli, Francesco Testa, Michael B Gorin, Samuel P Strom, Mette Bertelsen,[...]. Hum Mol Genet 2014
Jana Zernant, Yajing Angela Xie, Carmen Ayuso, Rosa Riveiro-Alvarez, Miguel-Angel Lopez-Martinez, Francesca Simonelli, Francesco Testa, Michael B Gorin, Samuel P Strom, Mette Bertelsen,[...]. Hum Mol Genet 2014
12
Mutation Spectrum of the ABCA4 Gene in 335 Stargardt Disease Patients From a Multicenter German Cohort-Impact of Selected Deep Intronic Variants and Common SNPs.
Heidi L Schulz, Felix Grassmann, Ulrich Kellner, Georg Spital, Klaus Rüther, Herbert Jägle, Karsten Hufendiek, Philipp Rating, Cord Huchzermeyer, Maria J Baier,[...]. Invest Ophthalmol Vis Sci 2017
Heidi L Schulz, Felix Grassmann, Ulrich Kellner, Georg Spital, Klaus Rüther, Herbert Jägle, Karsten Hufendiek, Philipp Rating, Cord Huchzermeyer, Maria J Baier,[...]. Invest Ophthalmol Vis Sci 2017
14
Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.
Tamara L Lenis, Jane Hu, Sze Yin Ng, Zhichun Jiang, Shanta Sarfare, Marcia B Lloyd, Nicholas J Esposito, William Samuel, Cynthia Jaworski, Dean Bok,[...]. Proc Natl Acad Sci U S A 2018
Tamara L Lenis, Jane Hu, Sze Yin Ng, Zhichun Jiang, Shanta Sarfare, Marcia B Lloyd, Nicholas J Esposito, William Samuel, Cynthia Jaworski, Dean Bok,[...]. Proc Natl Acad Sci U S A 2018
24
Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans.
Mi Sun Jin, Michael L Oldham, Qiuju Zhang, Jue Chen. Nature 2012
Mi Sun Jin, Michael L Oldham, Qiuju Zhang, Jue Chen. Nature 2012
10
Primary amines protect against retinal degeneration in mouse models of retinopathies.
Akiko Maeda, Marcin Golczak, Yu Chen, Kiichiro Okano, Hideo Kohno, Satomi Shiose, Kaede Ishikawa, William Harte, Grazyna Palczewska, Tadao Maeda,[...]. Nat Chem Biol 2011
Akiko Maeda, Marcin Golczak, Yu Chen, Kiichiro Okano, Hideo Kohno, Satomi Shiose, Kaede Ishikawa, William Harte, Grazyna Palczewska, Tadao Maeda,[...]. Nat Chem Biol 2011
10
Genetic and clinical analysis of ABCA4-associated disease in African American patients.
Jana Zernant, Frederick T Collison, Winston Lee, Gerald A Fishman, Kalev Noupuu, Bo Yuan, Carolyn Cai, James R Lupski, Lawrence A Yannuzzi, Stephen H Tsang,[...]. Hum Mutat 2014
Jana Zernant, Frederick T Collison, Winston Lee, Gerald A Fishman, Kalev Noupuu, Bo Yuan, Carolyn Cai, James R Lupski, Lawrence A Yannuzzi, Stephen H Tsang,[...]. Hum Mutat 2014
31
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.