A citation-based method for searching scientific literature

Tsuyoshi Hirota, Jae Wook Lee, Peter C St John, Mariko Sawa, Keiko Iwaisako, Takako Noguchi, Pagkapol Y Pongsawakul, Tim Sonntag, David K Welsh, David A Brenner, Francis J Doyle, Peter G Schultz, Steve A Kay. Science 2012
Times Cited: 286







List of co-cited articles
1523 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



A circadian gene expression atlas in mammals: implications for biology and medicine.
Ray Zhang, Nicholas F Lahens, Heather I Ballance, Michael E Hughes, John B Hogenesch. Proc Natl Acad Sci U S A 2014
33

Transcriptional architecture and chromatin landscape of the core circadian clock in mammals.
Nobuya Koike, Seung-Hee Yoo, Hung-Chung Huang, Vivek Kumar, Choogon Lee, Tae-Kyung Kim, Joseph S Takahashi. Science 2012
859
28

The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome.
Baokun He, Kazunari Nohara, Noheon Park, Yong-Sung Park, Bobby Guillory, Zhaoyang Zhao, Jose M Garcia, Nobuya Koike, Cheng Chi Lee, Joseph S Takahashi,[...]. Cell Metab 2016
239
27

High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.
Tsuyoshi Hirota, Jae Wook Lee, Warren G Lewis, Eric E Zhang, Ghislain Breton, Xianzhong Liu, Michael Garcia, Eric C Peters, Jean-Pierre Etchegaray, David Traver,[...]. PLoS Biol 2010
156
26

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.
Katja A Lamia, Stephanie J Papp, Ruth T Yu, Grant D Barish, N Henriette Uhlenhaut, Johan W Jonker, Michael Downes, Ronald M Evans. Nature 2011
357
25

Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems.
Zheng Chen, Seung-Hee Yoo, Joseph S Takahashi. Annu Rev Pharmacol Toxicol 2018
77
29

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.
Laura A Solt, Yongjun Wang, Subhashis Banerjee, Travis Hughes, Douglas J Kojetin, Thomas Lundasen, Youseung Shin, Jin Liu, Michael D Cameron, Romain Noel,[...]. Nature 2012
467
23

Isoform-selective regulation of mammalian cryptochromes.
Simon Miller, You Lee Son, Yoshiki Aikawa, Eri Makino, Yoshiko Nagai, Ashutosh Srivastava, Tsuyoshi Oshima, Akiko Sugiyama, Aya Hara, Kazuhiro Abe,[...]. Nat Chem Biol 2020
29
75

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta.
Tsuyoshi Hirota, Warren G Lewis, Andrew C Liu, Jae Wook Lee, Peter G Schultz, Steve A Kay. Proc Natl Acad Sci U S A 2008
206
21

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.
G T van der Horst, M Muijtjens, K Kobayashi, R Takano, S Kanno, M Takao, J de Wit, A Verkerk, A P Eker, D van Leenen,[...]. Nature 1999
976
20

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator.
Nicolas Preitner, Francesca Damiola, Luis Lopez-Molina, Joszef Zakany, Denis Duboule, Urs Albrecht, Ueli Schibler. Cell 2002
20


SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket.
Weiman Xing, Luca Busino, Thomas R Hinds, Samuel T Marionni, Nabiha H Saifee, Matthew F Bush, Michele Pagano, Ning Zheng. Nature 2013
146
20

Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.
Sandra M Siepka, Seung-Hee Yoo, Junghea Park, Weimin Song, Vivek Kumar, Yinin Hu, Choogon Lee, Joseph S Takahashi. Cell 2007
384
19

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.
Gabriele Sulli, Amy Rommel, Xiaojie Wang, Matthew J Kolar, Francesca Puca, Alan Saghatelian, Maksim V Plikus, Inder M Verma, Satchidananda Panda. Nature 2018
161
19

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.
Seung-Hee Yoo, Shin Yamazaki, Phillip L Lowrey, Kazuhiro Shimomura, Caroline H Ko, Ethan D Buhr, Sandra M Siepka, Hee-Kyung Hong, Won Jun Oh, Ook Joon Yoo,[...]. Proc Natl Acad Sci U S A 2004
18

SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.
Luca Busino, Florian Bassermann, Alessio Maiolica, Choogon Lee, Patrick M Nolan, Sofia I H Godinho, Giulio F Draetta, Michele Pagano. Science 2007
358
18

The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period.
Sofia I H Godinho, Elizabeth S Maywood, Linda Shaw, Valter Tucci, Alun R Barnard, Luca Busino, Michele Pagano, Rachel Kendall, Mohamed M Quwailid, M Rosario Romero,[...]. Science 2007
344
18

A synthetic cryptochrome inhibitor induces anti-proliferative effects and increases chemosensitivity in human breast cancer cells.
Sung Kook Chun, Sooyoung Chung, Hee-Dae Kim, Ju Hyung Lee, Jaebong Jang, Jeongah Kim, Doyeon Kim, Gi Hoon Son, Young J Oh, Young-Ger Suh,[...]. Biochem Biophys Res Commun 2015
26
69

Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder.
Alina Patke, Patricia J Murphy, Onur Emre Onat, Ana C Krieger, Tayfun Özçelik, Scott S Campbell, Michael W Young. Cell 2017
160
18

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock.
Zhen Dong, Guoxin Zhang, Meng Qu, Ryan C Gimple, Qiulian Wu, Zhixin Qiu, Briana C Prager, Xiuxing Wang, Leo J Y Kim, Andrew R Morton,[...]. Cancer Discov 2019
74
24

mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop.
K Kume, M J Zylka, S Sriram, L P Shearman, D R Weaver, X Jin, E S Maywood, M H Hastings, S M Reppert. Cell 1999
17

Diurnal transcriptome atlas of a primate across major neural and peripheral tissues.
Ludovic S Mure, Hiep D Le, Giorgia Benegiamo, Max W Chang, Luis Rios, Ngalla Jillani, Maina Ngotho, Thomas Kariuki, Ouria Dkhissi-Benyahya, Howard M Cooper,[...]. Science 2018
299
17

C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock.
Tsuyoshi Oshima, Iori Yamanaka, Anupriya Kumar, Junichiro Yamaguchi, Taeko Nishiwaki-Ohkawa, Kei Muto, Rika Kawamura, Tsuyoshi Hirota, Kazuhiro Yagita, Stephan Irle,[...]. Angew Chem Int Ed Engl 2015
40
40

Role of the CLOCK protein in the mammalian circadian mechanism.
N Gekakis, D Staknis, H B Nguyen, F C Davis, L D Wilsbacher, D P King, J S Takahashi, C J Weitz. Science 1998
16

GSK4112, a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.
Daniel Grant, Lei Yin, Jon L Collins, Derek J Parks, Lisa A Orband-Miller, G Bruce Wisely, Shree Joshi, Mitchell A Lazar, Timothy M Willson, William J Zuercher. ACS Chem Biol 2010
87
18

Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock.
Sung Kook Chun, Jaebong Jang, Sooyoung Chung, Hwayoung Yun, Nam-Jung Kim, Jong-Wha Jung, Gi Hoon Son, Young-Ger Suh, Kyungjin Kim. ACS Chem Biol 2014
38
42

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.
Tsuyoshi Oshima, Yoshimi Niwa, Keiko Kuwata, Ashutosh Srivastava, Tomoko Hyoda, Yoshiki Tsuchiya, Megumi Kumagai, Masato Tsuyuguchi, Teruya Tamaru, Akiko Sugiyama,[...]. Sci Adv 2019
53
30

CRY2 and FBXL3 Cooperatively Degrade c-MYC.
Anne-Laure Huber, Stephanie J Papp, Alanna B Chan, Emma Henriksson, Sabine D Jordan, Anna Kriebs, Madelena Nguyen, Martina Wallace, Zhizhong Li, Christian M Metallo,[...]. Mol Cell 2016
97
16

Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock.
Jae Wook Lee, Tsuyoshi Hirota, Anupriya Kumar, Nam-Jung Kim, Stephan Irle, Steve A Kay. ChemMedChem 2015
30
53

Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening.
Zheng Chen, Seung-Hee Yoo, Yong-Sung Park, Keon-Hee Kim, Shuguang Wei, Ethan Buhr, Zeng-You Ye, Hui-Lin Pan, Joseph S Takahashi. Proc Natl Acad Sci U S A 2012
124
16

Molecular architecture of the mammalian circadian clock.
Carrie L Partch, Carla B Green, Joseph S Takahashi. Trends Cell Biol 2014
729
16

Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.
M H Vitaterna, C P Selby, T Todo, H Niwa, C Thompson, E M Fruechte, K Hitomi, R J Thresher, T Ishikawa, J Miyazaki,[...]. Proc Natl Acad Sci U S A 1999
511
15

SIRT1 regulates circadian clock gene expression through PER2 deacetylation.
Gad Asher, David Gatfield, Markus Stratmann, Hans Reinke, Charna Dibner, Florian Kreppel, Raul Mostoslavsky, Frederick W Alt, Ueli Schibler. Cell 2008
913
15

Circadian time signatures of fitness and disease.
Joseph Bass, Mitchell A Lazar. Science 2016
283
15

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Biliana Marcheva, Kathryn Moynihan Ramsey, Ethan D Buhr, Yumiko Kobayashi, Hong Su, Caroline H Ko, Ganka Ivanova, Chiaki Omura, Shelley Mo, Martha H Vitaterna,[...]. Nature 2010
935
14


Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm.
Seung-Hee Yoo, Jennifer A Mohawk, Sandra M Siepka, Yongli Shan, Seong Kwon Huh, Hee-Kyung Hong, Izabela Kornblum, Vivek Kumar, Nobuya Koike, Ming Xu,[...]. Cell 2013
206
14

Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation.
Erik J Eide, Margaret F Woolf, Heeseog Kang, Peter Woolf, William Hurst, Fernando Camacho, Erica L Vielhaber, Andrew Giovanni, David M Virshup. Mol Cell Biol 2005
348
14

An evolutionary hotspot defines functional differences between CRYPTOCHROMES.
Clark Rosensweig, Kimberly A Reynolds, Peng Gao, Isara Laothamatas, Yongli Shan, Rama Ranganathan, Joseph S Takahashi, Carla B Green. Nat Commun 2018
41
34

CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.
Yasushi Isojima, Masato Nakajima, Hideki Ukai, Hiroshi Fujishima, Rikuhiro G Yamada, Koh-hei Masumoto, Reiko Kiuchi, Mayumi Ishida, Maki Ukai-Tadenuma, Yoichi Minami,[...]. Proc Natl Acad Sci U S A 2009
174
14

The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines.
Julie E Gibbs, John Blaikley, Stephen Beesley, Laura Matthews, Karen D Simpson, Susan H Boyce, Stuart N Farrow, Kathryn J Else, Dave Singh, David W Ray,[...]. Proc Natl Acad Sci U S A 2012
385
14

Coordinated transcription of key pathways in the mouse by the circadian clock.
Satchidananda Panda, Marina P Antoch, Brooke H Miller, Andrew I Su, Andrew B Schook, Marty Straume, Peter G Schultz, Steve A Kay, Joseph S Takahashi, John B Hogenesch. Cell 2002
13

FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes.
Arisa Hirano, Kanae Yumimoto, Ryosuke Tsunematsu, Masaki Matsumoto, Masaaki Oyama, Hiroko Kozuka-Hata, Tomoki Nakagawa, Darin Lanjakornsiripan, Keiichi I Nakayama, Yoshitaka Fukada. Cell 2013
159
13

AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.
Katja A Lamia, Uma M Sachdeva, Luciano DiTacchio, Elliot C Williams, Jacqueline G Alvarez, Daniel F Egan, Debbie S Vasquez, Henry Juguilon, Satchidananda Panda, Reuben J Shaw,[...]. Science 2009
577
13

Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1.
Alicia K Michael, Jennifer L Fribourgh, Yogarany Chelliah, Colby R Sandate, Greg L Hura, Dina Schneidman-Duhovny, Sarvind M Tripathi, Joseph S Takahashi, Carrie L Partch. Proc Natl Acad Sci U S A 2017
51
25

Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex.
Shannon N Nangle, Clark Rosensweig, Nobuya Koike, Hajime Tei, Joseph S Takahashi, Carla B Green, Ning Zheng. Elife 2014
64
20

A genome-wide RNAi screen for modifiers of the circadian clock in human cells.
Eric E Zhang, Andrew C Liu, Tsuyoshi Hirota, Loren J Miraglia, Genevieve Welch, Pagkapol Y Pongsawakul, Xianzhong Liu, Ann Atwood, Jon W Huss, Jeff Janes,[...]. Cell 2009
301
13

Optimized chemical probes for REV-ERBα.
Ryan P Trump, Stefano Bresciani, Anthony W J Cooper, James P Tellam, Justyna Wojno, John Blaikley, Lisa A Orband-Miller, Jennifer A Kashatus, Mohamed Boudjelal, Helen C Dawson,[...]. J Med Chem 2013
48
27


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.