Po-Hao Chang, Wendy W Hwang-Verslues, Yi-Cheng Chang, Chun-Chin Chen, Michael Hsiao, Yung-Ming Jeng, King-Jen Chang, Eva Y-H P Lee, Jin-Yuh Shew, Wen-Hwa Lee. Cancer Res 2012
Times Cited: 102
Times Cited: 102
Times Cited
Times Co-cited
Similarity
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion.
Akira Orimo, Piyush B Gupta, Dennis C Sgroi, Fernando Arenzana-Seisdedos, Thierry Delaunay, Rizwan Naeem, Vincent J Carey, Andrea L Richardson, Robert A Weinberg. Cell 2005
Akira Orimo, Piyush B Gupta, Dennis C Sgroi, Fernando Arenzana-Seisdedos, Thierry Delaunay, Rizwan Naeem, Vincent J Carey, Andrea L Richardson, Robert A Weinberg. Cell 2005
19
SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers.
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
16
SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium.
Rebecca Marlow, Phyllis Strickland, Ji Shin Lee, Xinyan Wu, Milana Pebenito, Mikhail Binnewies, Elizabeth K Le, Angel Moran, Hector Macias, Robert D Cardiff,[...]. Cancer Res 2008
Rebecca Marlow, Phyllis Strickland, Ji Shin Lee, Xinyan Wu, Milana Pebenito, Mikhail Binnewies, Elizabeth K Le, Angel Moran, Hector Macias, Robert D Cardiff,[...]. Cancer Res 2008
16
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Berna C Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L Carstens, Xiaofeng Zheng, Chia-Chin Wu, Tyler R Simpson, Hanane Laklai, Hikaru Sugimoto, Christoph Kahlert, Sergey V Novitskiy,[...]. Cancer Cell 2014
Berna C Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L Carstens, Xiaofeng Zheng, Chia-Chin Wu, Tyler R Simpson, Hanane Laklai, Hikaru Sugimoto, Christoph Kahlert, Sergey V Novitskiy,[...]. Cancer Cell 2014
16
SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
15
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Andrew D Rhim, Paul E Oberstein, Dafydd H Thomas, Emily T Mirek, Carmine F Palermo, Stephen A Sastra, Erin N Dekleva, Tyler Saunders, Claudia P Becerra, Ian W Tattersall,[...]. Cancer Cell 2014
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15
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.
Neta Erez, Morgan Truitt, Peter Olson, Sarah Tuttleton Arron, Douglas Hanahan. Cancer Cell 2010
Neta Erez, Morgan Truitt, Peter Olson, Sarah Tuttleton Arron, Douglas Hanahan. Cancer Cell 2010
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Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
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Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S Almeida, Mariano Ponz-Sarvise, Vincenzo Corbo, Tobiloba E Oni, Stephen A Hearn, Eun Jung Lee,[...]. J Exp Med 2017
Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S Almeida, Mariano Ponz-Sarvise, Vincenzo Corbo, Tobiloba E Oni, Stephen A Hearn, Eun Jung Lee,[...]. J Exp Med 2017
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Axon guidance factor SLIT2 inhibits neural invasion and metastasis in pancreatic cancer.
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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing.
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Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.
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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.
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Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.
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11
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
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Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells.
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Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
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11
Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts.
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Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer.
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11
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
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10
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
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10
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
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10
SLIT/ROBO1 signaling suppresses mammary branching morphogenesis by limiting basal cell number.
Hector Macias, Angel Moran, Yazeed Samara, Melissa Moreno, Jennifer E Compton, Gwyndolen Harburg, Phyllis Strickland, Lindsay Hinck. Dev Cell 2011
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14
The neuronal guidance cue Slit2 induces targeted migration and may play a role in brain metastasis of breast cancer cells.
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Identification of fibroblast heterogeneity in the tumor microenvironment.
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Matrix crosslinking forces tumor progression by enhancing integrin signaling.
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10
Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells.
Pravin J Mishra, Prasun J Mishra, Rita Humeniuk, Daniel J Medina, Gabriela Alexe, Jill P Mesirov, Sridhar Ganesan, John W Glod, Debabrata Banerjee. Cancer Res 2008
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10
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia.
Neil A Bhowmick, Anna Chytil, David Plieth, Agnieszka E Gorska, Nancy Dumont, Scott Shappell, M Kay Washington, Eric G Neilson, Harold L Moses. Science 2004
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10
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.
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10
The SLIT-ROBO pathway: a regulator of cell function with implications for the reproductive system.
Rachel E Dickinson, W Colin Duncan. Reproduction 2010
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10
SLIT2 axon guidance molecule is frequently inactivated in colorectal cancer and suppresses growth of colorectal carcinoma cells.
Ashraf Dallol, Dion Morton, Eamonn R Maher, Farida Latif. Cancer Res 2003
Ashraf Dallol, Dion Morton, Eamonn R Maher, Farida Latif. Cancer Res 2003
9
Novel roles for Slits and netrins: axon guidance cues as anticancer targets?
Patrick Mehlen, Céline Delloye-Bourgeois, Alain Chédotal. Nat Rev Cancer 2011
Patrick Mehlen, Céline Delloye-Bourgeois, Alain Chédotal. Nat Rev Cancer 2011
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The Slit/Robo system suppresses hepatocyte growth factor-dependent invasion and morphogenesis.
Maria Cristina Stella, Livio Trusolino, Paolo M Comoglio. Mol Biol Cell 2009
Maria Cristina Stella, Livio Trusolino, Paolo M Comoglio. Mol Biol Cell 2009
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Inactivation of SLIT2-ROBO1/2 pathway in premalignant lesions of uterine cervix: clinical and prognostic significances.
Sraboni Mitra, Dipanjana Mazumder-Indra, Ranajit K Mondal, Partha S Basu, Anup Roy, Susanta Roychoudhury, Chinmay K Panda. PLoS One 2012
Sraboni Mitra, Dipanjana Mazumder-Indra, Ranajit K Mondal, Partha S Basu, Anup Roy, Susanta Roychoudhury, Chinmay K Panda. PLoS One 2012
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Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling.
Y Yu, C-H Xiao, L-D Tan, Q-S Wang, X-Q Li, Y-M Feng. Br J Cancer 2014
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Carcinoma-associated fibroblasts: orchestrating the composition of malignancy.
Philippe Gascard, Thea D Tlsty. Genes Dev 2016
Philippe Gascard, Thea D Tlsty. Genes Dev 2016
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
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A framework for advancing our understanding of cancer-associated fibroblasts.
Erik Sahai, Igor Astsaturov, Edna Cukierman, David G DeNardo, Mikala Egeblad, Ronald M Evans, Douglas Fearon, Florian R Greten, Sunil R Hingorani, Tony Hunter,[...]. Nat Rev Cancer 2020
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9
Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells.
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
8
Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts.
Elisabeth M Zeisberg, Scott Potenta, Liang Xie, Michael Zeisberg, Raghu Kalluri. Cancer Res 2007
Elisabeth M Zeisberg, Scott Potenta, Liang Xie, Michael Zeisberg, Raghu Kalluri. Cancer Res 2007
8
Pten in stromal fibroblasts suppresses mammary epithelial tumours.
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8
Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.
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8
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells.
Cedric Gaggioli, Steven Hooper, Cristina Hidalgo-Carcedo, Robert Grosse, John F Marshall, Kevin Harrington, Erik Sahai. Nat Cell Biol 2007
Cedric Gaggioli, Steven Hooper, Cristina Hidalgo-Carcedo, Robert Grosse, John F Marshall, Kevin Harrington, Erik Sahai. Nat Cell Biol 2007
8
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.
Ravid Straussman, Teppei Morikawa, Kevin Shee, Michal Barzily-Rokni, Zhi Rong Qian, Jinyan Du, Ashli Davis, Margaret M Mongare, Joshua Gould, Dennie T Frederick,[...]. Nature 2012
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8
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Kenneth P Olive, Michael A Jacobetz, Christian J Davidson, Aarthi Gopinathan, Dominick McIntyre, Davina Honess, Basetti Madhu, Mae A Goldgraben, Meredith E Caldwell, David Allard,[...]. Science 2009
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8
Knockdown of Slit2 promotes growth and motility in gastric cancer cells via activation of AKT/β-catenin.
Rongliang Shi, Zhen Yang, Weiyan Liu, Bingya Liu, Ziping Xu, Ziping Zhang. Oncol Rep 2014
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Distinct epigenetic changes in the stromal cells of breast cancers.
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.