A citation-based method for searching scientific literature

A Christine Könner, Jens C Brüning. Cell Metab 2012
Times Cited: 175







List of co-cited articles
717 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus.
M A Cowley, J L Smart, M Rubinstein, M G Cerdán, S Diano, T L Horvath, R D Cone, M J Low. Nature 2001
11

Obesity is associated with hypothalamic injury in rodents and humans.
Joshua P Thaler, Chun-Xia Yi, Ellen A Schur, Stephan J Guyenet, Bang H Hwang, Marcelo O Dietrich, Xiaolin Zhao, David A Sarruf, Vitaly Izgur, Kenneth R Maravilla,[...]. J Clin Invest 2012
11

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.
A Christine Könner, Ruth Janoschek, Leona Plum, Sabine D Jordan, Eva Rother, Xiaosong Ma, Chun Xu, Pablo Enriori, Brigitte Hampel, Gregory S Barsh,[...]. Cell Metab 2007
446
10

Positional cloning of the mouse obese gene and its human homologue.
Y Zhang, R Proenca, M Maffei, M Barone, L Leopold, J M Friedman. Nature 1994
9

Leptin and the regulation of body weight in mammals.
J M Friedman, J L Halaas. Nature 1998
8

Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance.
Eva Tsaousidou, Lars Paeger, Bengt F Belgardt, Martin Pal, Claudia M Wunderlich, Hella Brönneke, Ursel Collienne, Brigitte Hampel, F Thomas Wunderlich, Marc Schmidt-Supprian,[...]. Cell Rep 2014
64
12

Central nervous system control of food intake.
M W Schwartz, S C Woods, D Porte, R J Seeley, D G Baskin. Nature 2000
7

Central nervous system control of food intake and body weight.
G J Morton, D E Cummings, D G Baskin, G S Barsh, M W Schwartz. Nature 2006
7

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.
Sophie M Steculorum, Johan Ruud, Ismene Karakasilioti, Heiko Backes, Linda Engström Ruud, Katharina Timper, Martin E Hess, Eva Tsaousidou, Jan Mauer, Merly C Vogt,[...]. Cell 2016
133
7

Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.
Marianne B Ernst, Claudia M Wunderlich, Simon Hess, Moritz Paehler, Andrea Mesaros, Sergei B Koralov, André Kleinridders, Andreas Husch, Heike Münzberg, Brigitte Hampel,[...]. J Neurosci 2009
115
7

High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
Tim Klöckener, Simon Hess, Bengt F Belgardt, Lars Paeger, Linda A W Verhagen, Andreas Husch, Jong-Woo Sohn, Brigitte Hampel, Harveen Dhillon, Jeffrey M Zigman,[...]. Nat Neurosci 2011
159
7


Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake.
Tadahiro Kitamura, Yun Feng, Yukari Ido Kitamura, Streamson C Chua, Allison W Xu, Gregory S Barsh, Luciano Rossetti, Domenico Accili. Nat Med 2006
314
6

NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates.
Serge Luquet, Francisco A Perez, Thomas S Hnasko, Richard D Palmiter. Science 2005
714
6

Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity.
Marciane Milanski, Giovanna Degasperi, Andressa Coope, Joseane Morari, Raphael Denis, Dennys E Cintra, Daniela M L Tsukumo, Gabriel Anhe, Maria E Amaral, Hilton K Takahashi,[...]. J Neurosci 2009
641
6

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.
Laura E Parton, Chian Ping Ye, Roberto Coppari, Pablo J Enriori, Brian Choi, Chen-Yu Zhang, Chun Xu, Claudia R Vianna, Nina Balthasar, Charlotte E Lee,[...]. Nature 2007
474
6

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity.
Xiaoqing Zhang, Guo Zhang, Hai Zhang, Michael Karin, Hua Bai, Dongsheng Cai. Cell 2008
908
6


Congenital leptin deficiency is associated with severe early-onset obesity in humans.
C T Montague, I S Farooqi, J P Whitehead, M A Soos, H Rau, N J Wareham, C P Sewter, J E Digby, S N Mohammed, J A Hurst,[...]. Nature 1997
5

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.
Umut Ozcan, Qiong Cao, Erkan Yilmaz, Ann-Hwee Lee, Neal N Iwakoshi, Esra Ozdelen, Gürol Tuncman, Cem Görgün, Laurie H Glimcher, Gökhan S Hotamisligil. Science 2004
5

Hypothalamic UDP Increases in Obesity and Promotes Feeding via P2Y6-Dependent Activation of AgRP Neurons.
Sophie M Steculorum, Lars Paeger, Stephan Bremser, Nadine Evers, Yvonne Hinze, Marco Idzko, Peter Kloppenburg, Jens C Brüning. Cell 2015
37
13

Agouti-related peptide-expressing neurons are mandatory for feeding.
Eva Gropp, Marya Shanabrough, Erzsebet Borok, Allison W Xu, Ruth Janoschek, Thorsten Buch, Leona Plum, Nina Balthasar, Brigitte Hampel, Ari Waisman,[...]. Nat Neurosci 2005
505
5

CNS leptin and insulin action in the control of energy homeostasis.
Bengt F Belgardt, Jens C Brüning. Ann N Y Acad Sci 2010
183
5

The catabolic action of insulin in the brain is mediated by melanocortins.
Stephen C Benoit, Ellen L Air, Lique M Coolen, Richelle Strauss, Alana Jackman, Deborah J Clegg, Randy J Seeley, Stephen C Woods. J Neurosci 2002
265
5



Rapid, reversible activation of AgRP neurons drives feeding behavior in mice.
Michael J Krashes, Shuichi Koda, ChianPing Ye, Sarah C Rogan, Andrew C Adams, Daniel S Cusher, Eleftheria Maratos-Flier, Bryan L Roth, Bradford B Lowell. J Clin Invest 2011
752
5

Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility.
Jennifer W Hill, Carol F Elias, Makoto Fukuda, Kevin W Williams, Eric D Berglund, William L Holland, You-Ree Cho, Jen-Chieh Chuang, Yong Xu, Michelle Choi,[...]. Cell Metab 2010
249
5

Inhibition of hypothalamic neuropeptide Y gene expression by insulin.
M W Schwartz, A J Sipols, J L Marks, G Sanacora, J D White, A Scheurink, S E Kahn, D G Baskin, S C Woods, D P Figlewicz. Endocrinology 1992
457
5

Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
Marc Schneeberger, Marcelo O Dietrich, David Sebastián, Mónica Imbernón, Carlos Castaño, Ainhoa Garcia, Yaiza Esteban, Alba Gonzalez-Franquesa, Ignacio Castrillón Rodríguez, Analía Bortolozzi,[...]. Cell 2013
330
5


Neurobiology of food intake in health and disease.
Gregory J Morton, Thomas H Meek, Michael W Schwartz. Nat Rev Neurosci 2014
327
5

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.
I S Farooqi, S A Jebb, G Langmack, E Lawrence, C H Cheetham, A M Prentice, I A Hughes, M A McCamish, S O'Rahilly. N Engl J Med 1999
5

Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.
Sabrina Diano, Zhong-Wu Liu, Jin Kwon Jeong, Marcelo O Dietrich, Hai-Bin Ruan, Esther Kim, Shigetomo Suyama, Kaitlin Kelly, Erika Gyengesi, Jack L Arbiser,[...]. Nat Med 2011
190
5

Leptin and insulin act on POMC neurons to promote the browning of white fat.
Garron T Dodd, Stephanie Decherf, Kim Loh, Stephanie E Simonds, Florian Wiede, Eglantine Balland, Troy L Merry, Heike Münzberg, Zhong-Yin Zhang, Barbara B Kahn,[...]. Cell 2015
213
5

Selective leptin resistance revisited.
Allyn L Mark. Am J Physiol Regul Integr Comp Physiol 2013
110
4

From mice to men: insights into the insulin resistance syndromes.
Sudha B Biddinger, C Ronald Kahn. Annu Rev Physiol 2006
489
4

Critical nodes in signalling pathways: insights into insulin action.
Cullen M Taniguchi, Brice Emanuelli, C Ronald Kahn. Nat Rev Mol Cell Biol 2006
4

Identification and expression cloning of a leptin receptor, OB-R.
L A Tartaglia, M Dembski, X Weng, N Deng, J Culpepper, R Devos, G J Richards, L A Campfield, F T Clark, J Deeds,[...]. Cell 1995
4

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB.
Dongsheng Cai, Minsheng Yuan, Daniel F Frantz, Peter A Melendez, Lone Hansen, Jongsoon Lee, Steven E Shoelson. Nat Med 2005
4

Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα.
Yan Lu, Xing Liu, Yang Jiao, Xuelian Xiong, E Wang, Xiaolin Wang, Zhijian Zhang, Huijie Zhang, Lingling Pan, Youfei Guan,[...]. J Clin Invest 2014
81
4

FoxO1 target Gpr17 activates AgRP neurons to regulate food intake.
Hongxia Ren, Ian J Orozco, Ya Su, Shigetomo Suyama, Roger Gutiérrez-Juárez, Tamas L Horvath, Sharon L Wardlaw, Leona Plum, Ottavio Arancio, Domenico Accili. Cell 2012
123
4

Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis.
Min-Seon Kim, Youngmi K Pak, Pil-Geum Jang, Cherl Namkoong, Yon-Sik Choi, Jong-Chul Won, Kyung-Sup Kim, Seung-Whan Kim, Hyo-Soo Kim, Joong-Yeol Park,[...]. Nat Neurosci 2006
228
4

Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.
Cláudio T De Souza, Eliana P Araujo, Silvana Bordin, Rika Ashimine, Ricardo L Zollner, Antonio C Boschero, Mário J A Saad, Lício A Velloso. Endocrinology 2005
677
4

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome.
W Fan, B A Boston, R A Kesterson, V J Hruby, R D Cone. Nature 1997
4

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet.
Kelly A Posey, Deborah J Clegg, Richard L Printz, Jaeman Byun, Gregory J Morton, Anuradha Vivekanandan-Giri, Subramaniam Pennathur, Denis G Baskin, Jay W Heinecke, Stephen C Woods,[...]. Am J Physiol Endocrinol Metab 2009
374
4


Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.
William L Holland, Benjamin T Bikman, Li-Ping Wang, Guan Yuguang, Katherine M Sargent, Sarada Bulchand, Trina A Knotts, Guanghou Shui, Deborah J Clegg, Markus R Wenk,[...]. J Clin Invest 2011
407
4

Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis.
Kevin W Williams, Tiemin Liu, Xingxing Kong, Makoto Fukuda, Yingfeng Deng, Eric D Berglund, Zhuo Deng, Yong Gao, Tianya Liu, Jong-Woo Sohn,[...]. Cell Metab 2014
158
4

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training.
Yexica Aponte, Deniz Atasoy, Scott M Sternson. Nat Neurosci 2011
627
4


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.