A citation-based method for searching scientific literature

Tomohiro Koga, Kunihiro Ichinose, Masayuki Mizui, José C Crispín, George C Tsokos. J Immunol 2012
Times Cited: 61







List of co-cited articles
668 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Systemic lupus erythematosus.
George C Tsokos. N Engl J Med 2011
47

CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance.
Tomohiro Koga, Christian M Hedrich, Masayuki Mizui, Nobuya Yoshida, Kotaro Otomo, Linda A Lieberman, Thomas Rauen, José C Crispín, George C Tsokos. J Clin Invest 2014
108
47

Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV.
Kunihiro Ichinose, Yuang-Taung Juang, José C Crispín, Katalin Kis-Toth, George C Tsokos. Arthritis Rheum 2011
60
43

Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV.
Yuang-Taung Juang, Ying Wang, Elena E Solomou, Yansong Li, Christian Mawrin, Klaus Tenbrock, Vasileios C Kyttaris, George C Tsokos. J Clin Invest 2005
153
40

KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3⁺ regulatory T cells in MRL/lpr mice.
Tomohiro Koga, Masayuki Mizui, Nobuya Yoshida, Kotaro Otomo, Linda A Lieberman, José C Crispín, George C Tsokos. Autoimmunity 2014
47
48

Cutting edge: Calcium/Calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis.
Kunihiro Ichinose, Thomas Rauen, Yuang-Taung Juang, Katalin Kis-Toth, Masayuki Mizui, Tomohiro Koga, George C Tsokos. J Immunol 2011
43
48


Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys.
José C Crispín, Mohamed Oukka, George Bayliss, Robert A Cohen, Christine A Van Beek, Isaac E Stillman, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Immunol 2008
477
29

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
194
27


Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.
David Fernandez, Eduardo Bonilla, Naureen Mirza, Brian Niland, Andras Perl. Arthritis Rheum 2006
200
22

cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus.
Christian M Hedrich, Jose C Crispin, Thomas Rauen, Christina Ioannidis, Sokratis A Apostolidis, Mindy S Lo, Vasileios C Kyttaris, George C Tsokos. Proc Natl Acad Sci U S A 2012
59
23


Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.
Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone,[...]. J Immunol 2013
75
21


Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
288
19

IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells.
Masayuki Mizui, Tomohiro Koga, Linda A Lieberman, Jessica Beltran, Nobuya Yoshida, Mark C Johnson, Roland Tisch, George C Tsokos. J Immunol 2014
65
18

cAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3+CD4-CD8- T cells in health and disease.
Christian M Hedrich, Thomas Rauen, Jose C Crispin, Tomohiro Koga, Christina Ioannidis, Melissa Zajdel, Vasileios C Kyttaris, George C Tsokos. J Biol Chem 2013
34
32

Lupus Nephritis IgG Induction of Calcium/Calmodulin-Dependent Protein Kinase IV Expression in Podocytes and Alteration of Their Function.
Kunihiro Ichinose, Takeshi Ushigusa, Ayako Nishino, Yosikazu Nakashima, Takahisa Suzuki, Yoshiro Horai, Tomohiro Koga, Shin-ya Kawashiri, Naoki Iwamoto, Mami Tamai,[...]. Arthritis Rheumatol 2016
33
33

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
David R Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A Middleton, Paul E Phillips, Mary K Crow, Stefanie Oess, Werner Muller-Esterl,[...]. J Immunol 2009
148
16

Calcium/Calmodulin-Dependent Kinase IV Facilitates the Recruitment of Interleukin-17-Producing Cells to Target Organs Through the CCR6/CCL20 Axis in Th17 Cell-Driven Inflammatory Diseases.
Tomohiro Koga, Kotaro Otomo, Masayuki Mizui, Nobuya Yoshida, Masataka Umeda, Kunihiro Ichinose, Atsushi Kawakami, George C Tsokos. Arthritis Rheumatol 2016
28
35

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus.
Caroline von Spee-Mayer, Elise Siegert, Dimas Abdirama, Angelika Rose, Anika Klaus, Tobias Alexander, Philipp Enghard, Birgit Sawitzki, Falk Hiepe, Andreas Radbruch,[...]. Ann Rheum Dis 2016
173
16

Phosphatase PP2A is requisite for the function of regulatory T cells.
Sokratis A Apostolidis, Noé Rodríguez-Rodríguez, Abel Suárez-Fueyo, Nikolina Dioufa, Esra Ozcan, José C Crispín, Maria G Tsokos, George C Tsokos. Nat Immunol 2016
115
16

Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
Jing He, Xia Zhang, Yunbo Wei, Xiaolin Sun, Yaping Chen, Jun Deng, Yuebo Jin, Yuzhou Gan, Xin Hu, Rulin Jia,[...]. Nat Med 2016
253
16


cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells.
Christian M Hedrich, José C Crispín, Thomas Rauen, Christina Ioannidis, Tomohiro Koga, Noe Rodriguez Rodriguez, Sokratis A Apostolidis, Vasileios C Kyttaris, George C Tsokos. J Biol Chem 2014
42
21

Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus.
Xavier Valencia, Cheryl Yarboro, Gabor Illei, Peter E Lipsky. J Immunol 2007
429
14

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.
Arian Laurence, Cristina M Tato, Todd S Davidson, Yuka Kanno, Zhi Chen, Zhengju Yao, Rebecca B Blank, Françoise Meylan, Richard Siegel, Lothar Hennighausen,[...]. Immunity 2007
14

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Greg M Delgoffe, Kristen N Pollizzi, Adam T Waickman, Emily Heikamp, David J Meyers, Maureen R Horton, Bo Xiao, Paul F Worley, Jonathan D Powell. Nat Immunol 2011
704
14

IL-17 and Th17 Cells.
Thomas Korn, Estelle Bettelli, Mohamed Oukka, Vijay K Kuchroo. Annu Rev Immunol 2009
14

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.
Partha S Biswas, Sanjay Gupta, Emily Chang, Li Song, Roslynn A Stirzaker, James K Liao, Govind Bhagat, Alessandra B Pernis. J Clin Invest 2010
148
14


Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
147
14

Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice.
Vasileios C Kyttaris, Zheng Zhang, Vijay K Kuchroo, Mohamed Oukka, George C Tsokos. J Immunol 2010
125
13

Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus.
Christina G Katsiari, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Clin Invest 2005
98
13

Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.
Yansong Li, Tatsuhiro Harada, Yuang-Taung Juang, Vasileios C Kyttaris, Ying Wang, Michael Zidanic, Kenneth Tung, George C Tsokos. J Immunol 2007
122
13


Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism.
José C Crispín, Sokratis A Apostolidis, Florencia Rosetti, Marton Keszei, Ninghai Wang, Cox Terhorst, Tanya N Mayadas, George C Tsokos. J Immunol 2012
37
21

Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodeling.
Sokratis A Apostolidis, Thomas Rauen, Christian M Hedrich, George C Tsokos, José C Crispín. J Biol Chem 2013
44
18

Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells.
Noé Rodríguez-Rodríguez, Sokratis A Apostolidis, Pablo Penaloza-MacMaster, José Manuel Martín Villa, Dan H Barouch, George C Tsokos, José C Crispín. J Immunol 2015
29
27

ICER is requisite for Th17 differentiation.
Nobuya Yoshida, Denis Comte, Masayuki Mizui, Kotaro Otomo, Florencia Rosetti, Tanya N Mayadas, José C Crispín, Sean J Bradley, Tomohiro Koga, Michihito Kono,[...]. Nat Commun 2016
31
25

Cutting Edge: Nanogel-Based Delivery of an Inhibitor of CaMK4 to CD4+ T Cells Suppresses Experimental Autoimmune Encephalomyelitis and Lupus-like Disease in Mice.
Kotaro Otomo, Tomohiro Koga, Masayuki Mizui, Nobuya Yoshida, Christina Kriegel, Sean Bickerton, Tarek M Fahmy, George C Tsokos. J Immunol 2015
29
27

The role of IL-23/IL-17 axis in lupus nephritis.
Zheng Zhang, Vasileios C Kyttaris, George C Tsokos. J Immunol 2009
207
11


Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.
David Saadoun, Michelle Rosenzwajg, Florence Joly, Adrien Six, Fabrice Carrat, Vincent Thibault, Damien Sene, Patrice Cacoub, David Klatzmann. N Engl J Med 2011
505
11

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.
Jens Y Humrich, Henner Morbach, Reinmar Undeutsch, Philipp Enghard, Stefan Rosenberger, Olivia Weigert, Lutz Kloke, Juliane Heimann, Timo Gaber, Susan Brandenburg,[...]. Proc Natl Acad Sci U S A 2010
99
11

Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity.
José C Crispín, Brendan T Keenan, Michele D Finnell, Bonnie L Bermas, Peter Schur, Elena Massarotti, Elizabeth W Karlson, Lisa M Fitzgerald, Sukran Ergin, Vasileios C Kyttaris,[...]. Arthritis Rheum 2010
42
16

Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus.
E E Solomou, Y T Juang, M F Gourley, G M Kammer, G C Tsokos. J Immunol 2001
140
11

Enhanced rho-associated protein kinase activation in patients with systemic lupus erythematosus.
Josephine Isgro, Sanjay Gupta, Elzbieta Jacek, Tanya Pavri, Roland Duculan, Mimi Kim, Kyriakos A Kirou, Jane E Salmon, Alessandra B Pernis. Arthritis Rheum 2013
40
17

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
John P Ray, Matthew M Staron, Justin A Shyer, Ping-Chih Ho, Heather D Marshall, Simon M Gray, Brian J Laidlaw, Koichi Araki, Rafi Ahmed, Susan M Kaech,[...]. Immunity 2015
167
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.