A citation-based method for searching scientific literature

Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan, Chung-Wei Lee, Di Hu, Bill Q Lian, Sonja Kleffel, Yijun Yang, James Neiswender, Abraham J Khorasani, Rui Fang, Cecilia Lezcano, Lyn M Duncan, Richard A Scolyer, John F Thompson, Hojabr Kakavand, Yariv Houvras, Leonard I Zon, Martin C Mihm, Ursula B Kaiser, Tobias Schatton, Bruce A Woda, George F Murphy, Yujiang G Shi. Cell 2012
Times Cited: 541







List of co-cited articles
960 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
39

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation.
H Yang, Y Liu, F Bai, J-Y Zhang, S-H Ma, J Liu, Z-D Xu, H-G Zhu, Z-Q Ling, D Ye,[...]. Oncogene 2013
403
31

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
31

5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations.
Seung-Gi Jin, Yong Jiang, Runxiang Qiu, Tibor A Rauch, Yinsheng Wang, Gabriele Schackert, Dietmar Krex, Qiang Lu, Gerd P Pfeifer. Cancer Res 2011
330
27

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
27

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.
Michael C Haffner, Alcides Chaux, Alan K Meeker, David M Esopi, Jonathan Gerber, Laxmi G Pellakuru, Antoun Toubaji, Pedram Argani, Christine Iacobuzio-Donahue, William G Nelson,[...]. Oncotarget 2011
314
26

Role of TET enzymes in DNA methylation, development, and cancer.
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
482
18


Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Wei Xu, Hui Yang, Ying Liu, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao,[...]. Cancer Cell 2011
17

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
17

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
942
15


Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian,[...]. Nat Biotechnol 2011
705
14

Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.
Yotaro Kudo, Keisuke Tateishi, Keisuke Yamamoto, Shinzo Yamamoto, Yoshinari Asaoka, Hideaki Ijichi, Genta Nagae, Haruhiko Yoshida, Hiroyuki Aburatani, Kazuhiko Koike. Cancer Sci 2012
206
14

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Maria E Figueroa, Omar Abdel-Wahab, Chao Lu, Patrick S Ward, Jay Patel, Alan Shih, Yushan Li, Neha Bhagwat, Aparna Vasanthakumar, Hugo F Fernandez,[...]. Cancer Cell 2010
13

5-Hydroxymethylcytosine is a predominantly stable DNA modification.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
304
12


Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.
Ruichuan Yin, Shi-Qing Mao, Bailin Zhao, Zechen Chong, Ying Yang, Chao Zhao, Dapeng Zhang, Hua Huang, Juan Gao, Zheng Li,[...]. J Am Chem Soc 2013
360
12

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.
Colm E Nestor, Raffaele Ottaviano, James Reddington, Duncan Sproul, Diana Reinhardt, Donncha Dunican, Elad Katz, J Michael Dixon, David J Harrison, Richard R Meehan. Genome Res 2012
282
12


Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Luisa Cimmino, Igor Dolgalev, Yubao Wang, Akihide Yoshimi, Gaëlle H Martin, Jingjing Wang, Victor Ng, Bo Xia, Matthew T Witkowski, Marisa Mitchell-Flack,[...]. Cell 2017
353
11

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
Gabriella Ficz, Miguel R Branco, Stefanie Seisenberger, Fátima Santos, Felix Krueger, Timothy A Hore, C Joana Marques, Simon Andrews, Wolf Reik. Nature 2011
804
11


Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
Bernard Thienpont, Jessica Steinbacher, Hui Zhao, Flora D'Anna, Anna Kuchnio, Athanasios Ploumakis, Bart Ghesquière, Laurien Van Dyck, Bram Boeckx, Luc Schoonjans,[...]. Nature 2016
320
11

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
Marian Mellén, Pinar Ayata, Scott Dewell, Skirmantas Kriaucionis, Nathaniel Heintz. Cell 2012
628
11

5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer.
Leonie I Kroeze, Bert A van der Reijden, Joop H Jansen. Biochim Biophys Acta 2015
69
15

Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1.
Chungang Liu, Limei Liu, Xuejiao Chen, Junjie Shen, Juanjuan Shan, Yanmin Xu, Zhi Yang, Lin Wu, Feng Xia, Ping Bie,[...]. PLoS One 2013
121
11

Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer.
Ke Chen, Jing Zhang, Zhongqiang Guo, Qin Ma, Zhengzheng Xu, Yuanyuan Zhou, Ziying Xu, Zhongwu Li, Yiqiang Liu, Xiongjun Ye,[...]. Cell Res 2016
92
11

5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages.
Chun-Xiao Song, Senlin Yin, Li Ma, Amanda Wheeler, Yu Chen, Yan Zhang, Bin Liu, Junjie Xiong, Weihan Zhang, Jiankun Hu,[...]. Cell Res 2017
107
11

Mutation in TET2 in myeloid cancers.
François Delhommeau, Sabrina Dupont, Véronique Della Valle, Chloé James, Severine Trannoy, Aline Massé, Olivier Kosmider, Jean-Pierre Le Couedic, Fabienne Robert, Antonio Alberdi,[...]. N Engl J Med 2009
11

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Keith E Szulwach, Xuekun Li, Yujing Li, Chun-Xiao Song, Hao Wu, Qing Dai, Hasan Irier, Anup K Upadhyay, Marla Gearing, Allan I Levey,[...]. Nat Neurosci 2011
551
10

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.
Brent A Orr, Michael C Haffner, William G Nelson, Srinivasan Yegnasubramanian, Charles G Eberhart. PLoS One 2012
128
10

TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases.
Chih-Hung Hsu, Kai-Lin Peng, Ming-Lun Kang, Yi-Ren Chen, Yu-Chih Yang, Chin-Hsien Tsai, Chi-Shen Chu, Yung-Ming Jeng, Yen-Ting Chen, Feng-Mao Lin,[...]. Cell Rep 2012
213
10

TET1 is a tumour suppressor that inhibits colon cancer growth by derepressing inhibitors of the WNT pathway.
F Neri, D Dettori, D Incarnato, A Krepelova, S Rapelli, M Maldotti, C Parlato, P Paliogiannis, S Oliviero. Oncogene 2015
127
10

The diverse roles of DNA methylation in mammalian development and disease.
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
543
10


5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients.
Kevin C Johnson, E Andres Houseman, Jessica E King, Katharine M von Herrmann, Camilo E Fadul, Brock C Christensen. Nat Commun 2016
69
13

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.
Kathryn Blaschke, Kevin T Ebata, Mohammad M Karimi, Jorge A Zepeda-Martínez, Preeti Goyal, Sahasransu Mahapatra, Angela Tam, Diana J Laird, Martin Hirst, Anjana Rao,[...]. Nature 2013
530
9

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription.
William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
558
9

Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.
Yufei Xu, Feizhen Wu, Li Tan, Lingchun Kong, Lijun Xiong, Jie Deng, Andrew J Barbera, Lijuan Zheng, Haikuo Zhang, Stephen Huang,[...]. Mol Cell 2011
442
9

Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.
Min-Zu Wu, Su-Feng Chen, Shin Nieh, Christopher Benner, Luo-Ping Ger, Chia-Ing Jan, Li Ma, Chien-Hung Chen, Tomoaki Hishida, Hong-Tai Chang,[...]. Cancer Res 2015
76
11

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
680
9

Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
Miao Yu, Gary C Hon, Keith E Szulwach, Chun-Xiao Song, Liang Zhang, Audrey Kim, Xuekun Li, Qing Dai, Yin Shen, Beomseok Park,[...]. Cell 2012
684
9

5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer.
Santiago Uribe-Lewis, Rory Stark, Thomas Carroll, Mark J Dunning, Martin Bachman, Yoko Ito, Lovorka Stojic, Silvia Halim, Sarah L Vowler, Andy G Lynch,[...]. Genome Biol 2015
48
18

Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas.
Tim Müller, Marco Gessi, Anke Waha, Lukas Jan Isselstein, Daniel Luxen, Dorothee Freihoff, Johannes Freihoff, Albert Becker, Matthias Simon, Jennifer Hammes,[...]. Am J Pathol 2012
85
10

5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers.
Wenshuai Li, Xu Zhang, Xingyu Lu, Lei You, Yanqun Song, Zhongguang Luo, Jun Zhang, Ji Nie, Wanwei Zheng, Diannan Xu,[...]. Cell Res 2017
138
9


Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.
Omar Abdel-Wahab, Ann Mullally, Cyrus Hedvat, Guillermo Garcia-Manero, Jay Patel, Martha Wadleigh, Sebastien Malinge, JinJuan Yao, Outi Kilpivaara, Rukhmi Bhat,[...]. Blood 2009
535
9

Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy.
Yan-Ping Xu, Lei Lv, Ying Liu, Matthew D Smith, Wen-Cai Li, Xian-Ming Tan, Meng Cheng, Zhijun Li, Michael Bovino, Jeffrey Aubé,[...]. J Clin Invest 2019
66
13

DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.