Chutima Talchai, Shouhong Xuan, Hua V Lin, Lori Sussel, Domenico Accili. Cell 2012
Times Cited: 872
Times Cited: 872
Times Cited
Times Co-cited
Similarity
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes.
Francesca Cinti, Ryotaro Bouchi, Ja Young Kim-Muller, Yoshiaki Ohmura, P R Sandoval, Matilde Masini, Lorella Marselli, Mara Suleiman, Lloyd E Ratner, Piero Marchetti,[...]. J Clin Endocrinol Metab 2016
Francesca Cinti, Ryotaro Bouchi, Ja Young Kim-Muller, Yoshiaki Ohmura, P R Sandoval, Matilde Masini, Lorella Marselli, Mara Suleiman, Lloyd E Ratner, Piero Marchetti,[...]. J Clin Endocrinol Metab 2016
38
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.
Alexandra E Butler, Juliette Janson, Susan Bonner-Weir, Robert Ritzel, Robert A Rizza, Peter C Butler. Diabetes 2003
Alexandra E Butler, Juliette Janson, Susan Bonner-Weir, Robert Ritzel, Robert A Rizza, Peter C Butler. Diabetes 2003
22
Inactivation of specific β cell transcription factors in type 2 diabetes.
Shuangli Guo, Chunhua Dai, Min Guo, Brandon Taylor, Jamie S Harmon, Maike Sander, R Paul Robertson, Alvin C Powers, Roland Stein. J Clin Invest 2013
Shuangli Guo, Chunhua Dai, Min Guo, Brandon Taylor, Jamie S Harmon, Maike Sander, R Paul Robertson, Alvin C Powers, Roland Stein. J Clin Invest 2013
20
Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions.
Mohammed Bensellam, Jean-Christophe Jonas, D Ross Laybutt. J Endocrinol 2018
Mohammed Bensellam, Jean-Christophe Jonas, D Ross Laybutt. J Endocrinol 2018
20
Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy.
Zhiyu Wang, Nathaniel W York, Colin G Nichols, Maria S Remedi. Cell Metab 2014
Zhiyu Wang, Nathaniel W York, Colin G Nichols, Maria S Remedi. Cell Metab 2014
18
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss.
Fabrizio Thorel, Virginie Népote, Isabelle Avril, Kenji Kohno, Renaud Desgraz, Simona Chera, Pedro L Herrera. Nature 2010
Fabrizio Thorel, Virginie Népote, Isabelle Avril, Kenji Kohno, Renaud Desgraz, Simona Chera, Pedro L Herrera. Nature 2010
14
Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.
Melissa F Brereton, Michaela Iberl, Kenju Shimomura, Quan Zhang, Alice E Adriaenssens, Peter Proks, Ioannis I Spiliotis, William Dace, Katia K Mattis, Reshma Ramracheya,[...]. Nat Commun 2014
Melissa F Brereton, Michaela Iberl, Kenju Shimomura, Quan Zhang, Alice E Adriaenssens, Peter Proks, Ioannis I Spiliotis, William Dace, Katia K Mattis, Reshma Ramracheya,[...]. Nat Commun 2014
13
Pdx1 maintains β cell identity and function by repressing an α cell program.
Tao Gao, Brian McKenna, Changhong Li, Maximilian Reichert, James Nguyen, Tarjinder Singh, Chenghua Yang, Archana Pannikar, Nicolai Doliba, Tingting Zhang,[...]. Cell Metab 2014
Tao Gao, Brian McKenna, Changhong Li, Maximilian Reichert, James Nguyen, Tarjinder Singh, Chenghua Yang, Archana Pannikar, Nicolai Doliba, Tingting Zhang,[...]. Cell Metab 2014
12
Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3.
Barak Blum, Siniša Hrvatin, Christian Schuetz, Claire Bonal, Alireza Rezania, Douglas A Melton. Nat Biotechnol 2012
Barak Blum, Siniša Hrvatin, Christian Schuetz, Claire Bonal, Alireza Rezania, Douglas A Melton. Nat Biotechnol 2012
11
The Role of Inflammation in β-cell Dedifferentiation.
Thierry M Nordmann, Erez Dror, Friederike Schulze, Shuyang Traub, Ekaterine Berishvili, Charlotte Barbieux, Marianne Böni-Schnetzler, Marc Y Donath. Sci Rep 2017
Thierry M Nordmann, Erez Dror, Friederike Schulze, Shuyang Traub, Ekaterine Berishvili, Charlotte Barbieux, Marianne Böni-Schnetzler, Marc Y Donath. Sci Rep 2017
12
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation.
Yuval Dor, Juliana Brown, Olga I Martinez, Douglas A Melton. Nature 2004
Yuval Dor, Juliana Brown, Olga I Martinez, Douglas A Melton. Nature 2004
11
Five stages of evolving beta-cell dysfunction during progression to diabetes.
Gordon C Weir, Susan Bonner-Weir. Diabetes 2004
Gordon C Weir, Susan Bonner-Weir. Diabetes 2004
10
Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells.
Alireza Rezania, Jennifer E Bruin, Payal Arora, Allison Rubin, Irina Batushansky, Ali Asadi, Shannon O'Dwyer, Nina Quiskamp, Majid Mojibian, Tobias Albrecht,[...]. Nat Biotechnol 2014
Alireza Rezania, Jennifer E Bruin, Payal Arora, Allison Rubin, Irina Batushansky, Ali Asadi, Shannon O'Dwyer, Nina Quiskamp, Majid Mojibian, Tobias Albrecht,[...]. Nat Biotechnol 2014
10
Generation of functional human pancreatic β cells in vitro.
Felicia W Pagliuca, Jeffrey R Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer Hyoje Ryu, Quinn P Peterson, Dale Greiner, Douglas A Melton. Cell 2014
Felicia W Pagliuca, Jeffrey R Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer Hyoje Ryu, Quinn P Peterson, Dale Greiner, Douglas A Melton. Cell 2014
9
β-Cell Dedifferentiation in Patients With T2D With Adequate Glucose Control and Nondiabetic Chronic Pancreatitis.
Jiajun Sun, Qicheng Ni, Jing Xie, Min Xu, Jun Zhang, Jie Kuang, Yanqiu Wang, Guang Ning, Qidi Wang. J Clin Endocrinol Metab 2019
Jiajun Sun, Qicheng Ni, Jing Xie, Min Xu, Jun Zhang, Jie Kuang, Yanqiu Wang, Guang Ning, Qidi Wang. J Clin Endocrinol Metab 2019
18
Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in db/db Mice.
Emi Ishida, Ja Young Kim-Muller, Domenico Accili. Diabetes 2017
Emi Ishida, Ja Young Kim-Muller, Domenico Accili. Diabetes 2017
23
FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction.
Yukari Ido Kitamura, Tadahiro Kitamura, Jan-Philipp Kruse, Jeffrey C Raum, Roland Stein, Wei Gu, Domenico Accili. Cell Metab 2005
Yukari Ido Kitamura, Tadahiro Kitamura, Jan-Philipp Kruse, Jeffrey C Raum, Roland Stein, Wei Gu, Domenico Accili. Cell Metab 2005
9
Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes.
J C Jonas, A Sharma, W Hasenkamp, H Ilkova, G Patanè, R Laybutt, S Bonner-Weir, G C Weir. J Biol Chem 1999
J C Jonas, A Sharma, W Hasenkamp, H Ilkova, G Patanè, R Laybutt, S Bonner-Weir, G C Weir. J Biol Chem 1999
9
Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure.
Décio L Eizirik, Lorenzo Pasquali, Miriam Cnop. Nat Rev Endocrinol 2020
Décio L Eizirik, Lorenzo Pasquali, Miriam Cnop. Nat Rev Endocrinol 2020
9
When β-cells fail: lessons from dedifferentiation.
D Accili, S C Talchai, J Y Kim-Muller, F Cinti, E Ishida, A M Ordelheide, T Kuo, J Fan, J Son. Diabetes Obes Metab 2016
D Accili, S C Talchai, J Y Kim-Muller, F Cinti, E Ishida, A M Ordelheide, T Kuo, J Fan, J Son. Diabetes Obes Metab 2016
14
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Åsa Segerstolpe, Athanasia Palasantza, Pernilla Eliasson, Eva-Marie Andersson, Anne-Christine Andréasson, Xiaoyan Sun, Simone Picelli, Alan Sabirsh, Maryam Clausen, Magnus K Bjursell,[...]. Cell Metab 2016
Åsa Segerstolpe, Athanasia Palasantza, Pernilla Eliasson, Eva-Marie Andersson, Anne-Christine Andréasson, Xiaoyan Sun, Simone Picelli, Alan Sabirsh, Maryam Clausen, Magnus K Bjursell,[...]. Cell Metab 2016
8
Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.
Simona Chera, Delphine Baronnier, Luiza Ghila, Valentina Cigliola, Jan N Jensen, Guoqiang Gu, Kenichiro Furuyama, Fabrizio Thorel, Fiona M Gribble, Frank Reimann,[...]. Nature 2014
Simona Chera, Delphine Baronnier, Luiza Ghila, Valentina Cigliola, Jan N Jensen, Guoqiang Gu, Kenichiro Furuyama, Fabrizio Thorel, Fiona M Gribble, Frank Reimann,[...]. Nature 2014
8
MafA is a key regulator of glucose-stimulated insulin secretion.
Chuan Zhang, Takashi Moriguchi, Miwako Kajihara, Ritsuko Esaki, Ayako Harada, Homare Shimohata, Hisashi Oishi, Michito Hamada, Naoki Morito, Kazuteru Hasegawa,[...]. Mol Cell Biol 2005
Chuan Zhang, Takashi Moriguchi, Miwako Kajihara, Ritsuko Esaki, Ayako Harada, Homare Shimohata, Hisashi Oishi, Michito Hamada, Naoki Morito, Kazuteru Hasegawa,[...]. Mol Cell Biol 2005
8
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.
Natalie R Johnston, Ryan K Mitchell, Elizabeth Haythorne, Maria Paiva Pessoa, Francesca Semplici, Jorge Ferrer, Lorenzo Piemonti, Piero Marchetti, Marco Bugliani, Domenico Bosco,[...]. Cell Metab 2016
Natalie R Johnston, Ryan K Mitchell, Elizabeth Haythorne, Maria Paiva Pessoa, Francesca Semplici, Jorge Ferrer, Lorenzo Piemonti, Piero Marchetti, Marco Bugliani, Domenico Bosco,[...]. Cell Metab 2016
8
Pancreatic beta-cell mass in European subjects with type 2 diabetes.
J Rahier, Y Guiot, R M Goebbels, C Sempoux, J C Henquin. Diabetes Obes Metab 2008
J Rahier, Y Guiot, R M Goebbels, C Sempoux, J C Henquin. Diabetes Obes Metab 2008
8
Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice.
Ja Young Kim-Muller, Shangang Zhao, Shekhar Srivastava, Yves Mugabo, Hye-Lim Noh, YoungJung R Kim, S R Murthy Madiraju, Anthony W Ferrante, Edward Y Skolnik, Marc Prentki,[...]. Cell Metab 2014
Ja Young Kim-Muller, Shangang Zhao, Shekhar Srivastava, Yves Mugabo, Hye-Lim Noh, YoungJung R Kim, S R Murthy Madiraju, Anthony W Ferrante, Edward Y Skolnik, Marc Prentki,[...]. Cell Metab 2014
12
Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes.
Cristina Aguayo-Mazzucato, Joshua Andle, Terrence B Lee, Ayush Midha, Lindsay Talemal, Vaja Chipashvili, Jennifer Hollister-Lock, Jan van Deursen, Gordon Weir, Susan Bonner-Weir. Cell Metab 2019
Cristina Aguayo-Mazzucato, Joshua Andle, Terrence B Lee, Ayush Midha, Lindsay Talemal, Vaja Chipashvili, Jennifer Hollister-Lock, Jan van Deursen, Gordon Weir, Susan Bonner-Weir. Cell Metab 2019
8
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
Barak Blum, Adam N Roose, Ornella Barrandon, René Maehr, Anthony C Arvanites, Lance S Davidow, Jeffrey C Davis, Quinn P Peterson, Lee L Rubin, Douglas A Melton. Elife 2014
Barak Blum, Adam N Roose, Ornella Barrandon, René Maehr, Anthony C Arvanites, Lance S Davidow, Jeffrey C Davis, Quinn P Peterson, Lee L Rubin, Douglas A Melton. Elife 2014
9
Metabolic Stress and Compromised Identity of Pancreatic Beta Cells.
Avital Swisa, Benjamin Glaser, Yuval Dor. Front Genet 2017
Avital Swisa, Benjamin Glaser, Yuval Dor. Front Genet 2017
12
Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.
Brandon L Taylor, Fen-Fen Liu, Maike Sander. Cell Rep 2013
Brandon L Taylor, Fen-Fen Liu, Maike Sander. Cell Rep 2013
8
Conversion of mature human β-cells into glucagon-producing α-cells.
H Siebe Spijker, Raimond B G Ravelli, A Mieke Mommaas-Kienhuis, Aart A van Apeldoorn, Marten A Engelse, Arnaud Zaldumbide, Susan Bonner-Weir, Ton J Rabelink, Rob C Hoeben, Hans Clevers,[...]. Diabetes 2013
H Siebe Spijker, Raimond B G Ravelli, A Mieke Mommaas-Kienhuis, Aart A van Apeldoorn, Marten A Engelse, Arnaud Zaldumbide, Susan Bonner-Weir, Ton J Rabelink, Rob C Hoeben, Hans Clevers,[...]. Diabetes 2013
8
Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis.
Chunguang Chen, Christian M Cohrs, Julia Stertmann, Robert Bozsak, Stephan Speier. Mol Metab 2017
Chunguang Chen, Christian M Cohrs, Julia Stertmann, Robert Bozsak, Stephan Speier. Mol Metab 2017
8
Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes.
Cristina Aguayo-Mazzucato, Susan Bonner-Weir. Cell Metab 2018
Cristina Aguayo-Mazzucato, Susan Bonner-Weir. Cell Metab 2018
7
β Cell Aging Markers Have Heterogeneous Distribution and Are Induced by Insulin Resistance.
Cristina Aguayo-Mazzucato, Mark van Haaren, Magdalena Mruk, Terence B Lee, Caitlin Crawford, Jennifer Hollister-Lock, Brooke A Sullivan, James W Johnson, Aref Ebrahimi, Jonathan M Dreyfuss,[...]. Cell Metab 2017
Cristina Aguayo-Mazzucato, Mark van Haaren, Magdalena Mruk, Terence B Lee, Caitlin Crawford, Jennifer Hollister-Lock, Brooke A Sullivan, James W Johnson, Aref Ebrahimi, Jonathan M Dreyfuss,[...]. Cell Metab 2017
7
7
Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.
Xiangwei Xiao, Ping Guo, Chiyo Shiota, Ting Zhang, Gina M Coudriet, Shane Fischbach, Krishna Prasadan, Joseph Fusco, Sabarinathan Ramachandran, Piotr Witkowski,[...]. Cell Stem Cell 2018
Xiangwei Xiao, Ping Guo, Chiyo Shiota, Ting Zhang, Gina M Coudriet, Shane Fischbach, Krishna Prasadan, Joseph Fusco, Sabarinathan Ramachandran, Piotr Witkowski,[...]. Cell Stem Cell 2018
8
Cellular and molecular mechanisms coordinating pancreas development.
Aimée Bastidas-Ponce, Katharina Scheibner, Heiko Lickert, Mostafa Bakhti. Development 2017
Aimée Bastidas-Ponce, Katharina Scheibner, Heiko Lickert, Mostafa Bakhti. Development 2017
8
The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.
Monica Courtney, Elisabet Gjernes, Noémie Druelle, Christophe Ravaud, Andhira Vieira, Nouha Ben-Othman, Anja Pfeifer, Fabio Avolio, Gunter Leuckx, Sandra Lacas-Gervais,[...]. PLoS Genet 2013
Monica Courtney, Elisabet Gjernes, Noémie Druelle, Christophe Ravaud, Andhira Vieira, Nouha Ben-Othman, Anja Pfeifer, Fabio Avolio, Gunter Leuckx, Sandra Lacas-Gervais,[...]. PLoS Genet 2013
7
Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.
Juris J Meier, Alexandra E Butler, Yoshifumi Saisho, Travis Monchamp, Ryan Galasso, Anil Bhushan, Robert A Rizza, Peter C Butler. Diabetes 2008
Juris J Meier, Alexandra E Butler, Yoshifumi Saisho, Travis Monchamp, Ryan Galasso, Anil Bhushan, Robert A Rizza, Peter C Butler. Diabetes 2008
7
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function.
Over Cabrera, Dora M Berman, Norma S Kenyon, Camillo Ricordi, Per-Olof Berggren, Alejandro Caicedo. Proc Natl Acad Sci U S A 2006
Over Cabrera, Dora M Berman, Norma S Kenyon, Camillo Ricordi, Per-Olof Berggren, Alejandro Caicedo. Proc Natl Acad Sci U S A 2006
7
Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.
Chad S Hunter, Roland W Stein. Front Genet 2017
Chad S Hunter, Roland W Stein. Front Genet 2017
15
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.
Elizabeth Haythorne, Maria Rohm, Martijn van de Bunt, Melissa F Brereton, Andrei I Tarasov, Thomas S Blacker, Gregor Sachse, Mariana Silva Dos Santos, Raul Terron Exposito, Simon Davis,[...]. Nat Commun 2019
Elizabeth Haythorne, Maria Rohm, Martijn van de Bunt, Melissa F Brereton, Andrei I Tarasov, Thomas S Blacker, Gregor Sachse, Mariana Silva Dos Santos, Raul Terron Exposito, Simon Davis,[...]. Nat Commun 2019
7
Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes.
Maria Lytrivi, Anne-Laure Castell, Vincent Poitout, Miriam Cnop. J Mol Biol 2020
Maria Lytrivi, Anne-Laure Castell, Vincent Poitout, Miriam Cnop. J Mol Biol 2020
7
Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.
E L Lim, K G Hollingsworth, B S Aribisala, M J Chen, J C Mathers, R Taylor. Diabetologia 2011
E L Lim, K G Hollingsworth, B S Aribisala, M J Chen, J C Mathers, R Taylor. Diabetologia 2011
7
Natural history of β-cell adaptation and failure in type 2 diabetes.
Emilyn U Alejandro, Brigid Gregg, Manuel Blandino-Rosano, Corentin Cras-Méneur, Ernesto Bernal-Mizrachi. Mol Aspects Med 2015
Emilyn U Alejandro, Brigid Gregg, Manuel Blandino-Rosano, Corentin Cras-Méneur, Ernesto Bernal-Mizrachi. Mol Aspects Med 2015
6
RNA-Seq Analysis of Islets to Characterise the Dedifferentiation in Type 2 Diabetes Model Mice db/db.
Abraham Neelankal John, Ramesh Ram, Fang-Xu Jiang. Endocr Pathol 2018
Abraham Neelankal John, Ramesh Ram, Fang-Xu Jiang. Endocr Pathol 2018
16
β-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity.
Teresa Mezza, Francesca Cinti, Chiara Maria Assunta Cefalo, Alfredo Pontecorvi, Rohit N Kulkarni, Andrea Giaccari. Diabetes 2019
Teresa Mezza, Francesca Cinti, Chiara Maria Assunta Cefalo, Alfredo Pontecorvi, Rohit N Kulkarni, Andrea Giaccari. Diabetes 2019
10
β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
Philippe A Halban, Kenneth S Polonsky, Donald W Bowden, Meredith A Hawkins, Charlotte Ling, Kieren J Mather, Alvin C Powers, Christopher J Rhodes, Lori Sussel, Gordon C Weir. Diabetes Care 2014
Philippe A Halban, Kenneth S Polonsky, Donald W Bowden, Meredith A Hawkins, Charlotte Ling, Kieren J Mather, Alvin C Powers, Christopher J Rhodes, Lori Sussel, Gordon C Weir. Diabetes Care 2014
6
Type 2 Diabetes: The Pathologic Basis of Reversible β-Cell Dysfunction.
Michael G White, James A M Shaw, Roy Taylor. Diabetes Care 2016
Michael G White, James A M Shaw, Roy Taylor. Diabetes Care 2016
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.