Driss El Moustaine, Sébastien Granier, Etienne Doumazane, Pauline Scholler, Rita Rahmeh, Patrick Bron, Bernard Mouillac, Jean-Louis Banères, Philippe Rondard, Jean-Philippe Pin. Proc Natl Acad Sci U S A 2012
Times Cited: 120
Times Cited: 120
Times Cited
Times Co-cited
Similarity
A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
42
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan,[...]. Nature 2014
Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan,[...]. Nature 2014
36
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.
Huixian Wu, Chong Wang, Karen J Gregory, Gye Won Han, Hyekyung P Cho, Yan Xia, Colleen M Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov,[...]. Science 2014
Huixian Wu, Chong Wang, Karen J Gregory, Gye Won Han, Hyekyung P Cho, Yan Xia, Colleen M Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov,[...]. Science 2014
36
Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
Li Xue, Xavier Rovira, Pauline Scholler, Han Zhao, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Nat Chem Biol 2015
Li Xue, Xavier Rovira, Pauline Scholler, Han Zhao, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Nat Chem Biol 2015
36
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
N Kunishima, Y Shimada, Y Tsuji, T Sato, M Yamamoto, T Kumasaka, S Nakanishi, H Jingami, K Morikawa. Nature 2000
N Kunishima, Y Shimada, Y Tsuji, T Sato, M Yamamoto, T Kumasaka, S Nakanishi, H Jingami, K Morikawa. Nature 2000
34
Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
31
Structures of the extracellular regions of the group II/III metabotropic glutamate receptors.
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami. Proc Natl Acad Sci U S A 2007
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami. Proc Natl Acad Sci U S A 2007
29
Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Eric Trinquet, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2013
Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Eric Trinquet, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2013
40
Identification of a serotonin/glutamate receptor complex implicated in psychosis.
Javier González-Maeso, Rosalind L Ang, Tony Yuen, Pokman Chan, Noelia V Weisstaub, Juan F López-Giménez, Mingming Zhou, Yuuya Okawa, Luis F Callado, Graeme Milligan,[...]. Nature 2008
Javier González-Maeso, Rosalind L Ang, Tony Yuen, Pokman Chan, Noelia V Weisstaub, Juan F López-Giménez, Mingming Zhou, Yuuya Okawa, Luis F Callado, Graeme Milligan,[...]. Nature 2008
28
Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.
Joshua Levitz, Chris Habrian, Shashank Bharill, Zhu Fu, Reza Vafabakhsh, Ehud Y Isacoff. Neuron 2016
Joshua Levitz, Chris Habrian, Shashank Bharill, Zhu Fu, Reza Vafabakhsh, Ehud Y Isacoff. Neuron 2016
28
Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Søren G F Rasmussen, Brian T DeVree, Yaozhong Zou, Andrew C Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski,[...]. Nature 2011
Søren G F Rasmussen, Brian T DeVree, Yaozhong Zou, Andrew C Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski,[...]. Nature 2011
24
Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.
Shen Yin, Meredith J Noetzel, Kari A Johnson, Rocio Zamorano, Nidhi Jalan-Sakrikar, Karen J Gregory, P Jeffrey Conn, Colleen M Niswender. J Neurosci 2014
Shen Yin, Meredith J Noetzel, Kari A Johnson, Rocio Zamorano, Nidhi Jalan-Sakrikar, Karen J Gregory, P Jeffrey Conn, Colleen M Niswender. J Neurosci 2014
30
Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.
Julie Kniazeff, Anne-Sophie Bessis, Damien Maurel, Hervé Ansanay, Laurent Prézeau, Jean-Philippe Pin. Nat Struct Mol Biol 2004
Julie Kniazeff, Anne-Sophie Bessis, Damien Maurel, Hervé Ansanay, Laurent Prézeau, Jean-Philippe Pin. Nat Struct Mol Biol 2004
23
Metabotropic glutamate receptor 5 is a disulfide-linked dimer.
C Romano, W L Yang, K L O'Malley. J Biol Chem 1996
C Romano, W L Yang, K L O'Malley. J Biol Chem 1996
22
Conformational dynamics of a class C G-protein-coupled receptor.
Reza Vafabakhsh, Joshua Levitz, Ehud Y Isacoff. Nature 2015
Reza Vafabakhsh, Joshua Levitz, Ehud Y Isacoff. Nature 2015
22
Organization and functions of mGlu and GABAB receptor complexes.
Jean-Philippe Pin, Bernhard Bettler. Nature 2016
Jean-Philippe Pin, Bernhard Bettler. Nature 2016
22
Structural insights into the activation of metabotropic glutamate receptors.
Antoine Koehl, Hongli Hu, Dan Feng, Bingfa Sun, Yan Zhang, Michael J Robertson, Matthew Chu, Tong Sun Kobilka, Toon Laeremans, Jan Steyaert,[...]. Nature 2019
Antoine Koehl, Hongli Hu, Dan Feng, Bingfa Sun, Yan Zhang, Michael J Robertson, Matthew Chu, Tong Sun Kobilka, Toon Laeremans, Jan Steyaert,[...]. Nature 2019
22
Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Daisuke Tsuchiya, Naoki Kunishima, Narutoshi Kamiya, Hisato Jingami, Kosuke Morikawa. Proc Natl Acad Sci U S A 2002
Daisuke Tsuchiya, Naoki Kunishima, Narutoshi Kamiya, Hisato Jingami, Kosuke Morikawa. Proc Natl Acad Sci U S A 2002
20
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.
Damien Maurel, Laëtitia Comps-Agrar, Carsten Brock, Marie-Laure Rives, Emmanuel Bourrier, Mohammed Akli Ayoub, Hervé Bazin, Norbert Tinel, Thierry Durroux, Laurent Prézeau,[...]. Nat Methods 2008
Damien Maurel, Laëtitia Comps-Agrar, Carsten Brock, Marie-Laure Rives, Emmanuel Bourrier, Mohammed Akli Ayoub, Hervé Bazin, Norbert Tinel, Thierry Durroux, Laurent Prézeau,[...]. Nat Methods 2008
20
Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs.
Miguel Fribourg, José L Moreno, Terrell Holloway, Davide Provasi, Lia Baki, Rahul Mahajan, Gyu Park, Scott K Adney, Candice Hatcher, José M Eltit,[...]. Cell 2011
Miguel Fribourg, José L Moreno, Terrell Holloway, Davide Provasi, Lia Baki, Rahul Mahajan, Gyu Park, Scott K Adney, Candice Hatcher, José M Eltit,[...]. Cell 2011
18
Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile).
John A Christopher, Sarah J Aves, Kirstie A Bennett, Andrew S Doré, James C Errey, Ali Jazayeri, Fiona H Marshall, Krzysztof Okrasa, Maria J Serrano-Vega, Benjamin G Tehan,[...]. J Med Chem 2015
John A Christopher, Sarah J Aves, Kirstie A Bennett, Andrew S Doré, James C Errey, Ali Jazayeri, Fiona H Marshall, Krzysztof Okrasa, Maria J Serrano-Vega, Benjamin G Tehan,[...]. J Med Chem 2015
18
Dimers and beyond: The functional puzzles of class C GPCRs.
Julie Kniazeff, Laurent Prézeau, Philippe Rondard, Jean-Philippe Pin, Cyril Goudet. Pharmacol Ther 2011
Julie Kniazeff, Laurent Prézeau, Philippe Rondard, Jean-Philippe Pin, Cyril Goudet. Pharmacol Ther 2011
17
Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy.
Linnea Olofsson, Suren Felekyan, Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Philippe Rondard, Claus A M Seidel, Jean-Philippe Pin, Emmanuel Margeat. Nat Commun 2014
Linnea Olofsson, Suren Felekyan, Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Philippe Rondard, Claus A M Seidel, Jean-Philippe Pin, Emmanuel Margeat. Nat Commun 2014
26
Interdomain movements in metabotropic glutamate receptor activation.
Siluo Huang, Jianhua Cao, Ming Jiang, Gilles Labesse, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2011
Siluo Huang, Jianhua Cao, Ming Jiang, Gilles Labesse, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2011
27
Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
Cyril Goudet, Florence Gaven, Julie Kniazeff, Claire Vol, Jiangfeng Liu, Martin Cohen-Gonsaud, Francine Acher, Laurent Prézeau, Jean Philippe Pin. Proc Natl Acad Sci U S A 2004
Cyril Goudet, Florence Gaven, Julie Kniazeff, Claire Vol, Jiangfeng Liu, Martin Cohen-Gonsaud, Francine Acher, Laurent Prézeau, Jean Philippe Pin. Proc Natl Acad Sci U S A 2004
15
Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.
Veronika Hlavackova, Ulrike Zabel, Daniela Frankova, Julia Bätz, Carsten Hoffmann, Laurent Prezeau, Jean-Philippe Pin, Jaroslav Blahos, Martin J Lohse. Sci Signal 2012
Veronika Hlavackova, Ulrike Zabel, Daniela Frankova, Julia Bätz, Carsten Hoffmann, Laurent Prezeau, Jean-Philippe Pin, Jaroslav Blahos, Martin J Lohse. Sci Signal 2012
25
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
Jean-Philippe Pin, Thierry Galvez, Laurent Prézeau. Pharmacol Ther 2003
Jean-Philippe Pin, Thierry Galvez, Laurent Prézeau. Pharmacol Ther 2003
15
G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives.
Sergi Ferré, Vicent Casadó, Lakshmi A Devi, Marta Filizola, Ralf Jockers, Martin J Lohse, Graeme Milligan, Jean-Philippe Pin, Xavier Guitart. Pharmacol Rev 2014
Sergi Ferré, Vicent Casadó, Lakshmi A Devi, Marta Filizola, Ralf Jockers, Martin J Lohse, Graeme Milligan, Jean-Philippe Pin, Xavier Guitart. Pharmacol Rev 2014
15
Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization.
Davide Calebiro, Finn Rieken, Julia Wagner, Titiwat Sungkaworn, Ulrike Zabel, Alfio Borzi, Emanuele Cocucci, Alexander Zürn, Martin J Lohse. Proc Natl Acad Sci U S A 2013
Davide Calebiro, Finn Rieken, Julia Wagner, Titiwat Sungkaworn, Ulrike Zabel, Alfio Borzi, Emanuele Cocucci, Alexander Zürn, Martin J Lohse. Proc Natl Acad Sci U S A 2013
15
Structural mechanism of ligand activation in human GABA(B) receptor.
Yong Geng, Martin Bush, Lidia Mosyak, Feng Wang, Qing R Fan. Nature 2013
Yong Geng, Martin Bush, Lidia Mosyak, Feng Wang, Qing R Fan. Nature 2013
15
Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.
Cyril Goudet, Julie Kniazeff, Veronika Hlavackova, Fanny Malhaire, Damien Maurel, Francine Acher, Jaroslav Blahos, Laurent Prézeau, Jean-Philippe Pin. J Biol Chem 2005
Cyril Goudet, Julie Kniazeff, Veronika Hlavackova, Fanny Malhaire, Damien Maurel, Francine Acher, Jaroslav Blahos, Laurent Prézeau, Jean-Philippe Pin. J Biol Chem 2005
15
Structural diversity of G protein-coupled receptors and significance for drug discovery.
Malin C Lagerström, Helgi B Schiöth. Nat Rev Drug Discov 2008
Malin C Lagerström, Helgi B Schiöth. Nat Rev Drug Discov 2008
14
Functional and pharmacological characteristics of metabotropic glutamate receptors 2/4 heterodimers.
Paul J Kammermeier. Mol Pharmacol 2012
Paul J Kammermeier. Mol Pharmacol 2012
26
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.
Matthew R Whorton, Michael P Bokoch, Søren G F Rasmussen, Bo Huang, Richard N Zare, Brian Kobilka, Roger K Sunahara. Proc Natl Acad Sci U S A 2007
Matthew R Whorton, Michael P Bokoch, Søren G F Rasmussen, Bo Huang, Richard N Zare, Brian Kobilka, Roger K Sunahara. Proc Natl Acad Sci U S A 2007
14
Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.
David Moreno Delgado, Thor C Møller, Jeanne Ster, Jesús Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M Zwier, Julie Perroy, Thierry Durroux,[...]. Elife 2017
David Moreno Delgado, Thor C Møller, Jeanne Ster, Jesús Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M Zwier, Julie Perroy, Thierry Durroux,[...]. Elife 2017
33
Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1alpha.
Michihiro Tateyama, Hideki Abe, Hiroyasu Nakata, Osamu Saito, Yoshihiro Kubo. Nat Struct Mol Biol 2004
Michihiro Tateyama, Hideki Abe, Hiroyasu Nakata, Osamu Saito, Yoshihiro Kubo. Nat Struct Mol Biol 2004
13
Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.
Veronika Hlavackova, Cyril Goudet, Julie Kniazeff, Alice Zikova, Damien Maurel, Claire Vol, Johana Trojanova, Laurent Prézeau, Jean-Philippe Pin, Jaroslav Blahos. EMBO J 2005
Veronika Hlavackova, Cyril Goudet, Julie Kniazeff, Alice Zikova, Damien Maurel, Claire Vol, Johana Trojanova, Laurent Prézeau, Jean-Philippe Pin, Jaroslav Blahos. EMBO J 2005
13
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.
Aashish Manglik, Andrew C Kruse, Tong Sun Kobilka, Foon Sun Thian, Jesper M Mathiesen, Roger K Sunahara, Leonardo Pardo, William I Weis, Brian K Kobilka, Sébastien Granier. Nature 2012
Aashish Manglik, Andrew C Kruse, Tong Sun Kobilka, Foon Sun Thian, Jesper M Mathiesen, Roger K Sunahara, Leonardo Pardo, William I Weis, Brian K Kobilka, Sébastien Granier. Nature 2012
12
Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher-order oligomers in living cells.
Nuria Cabello, Jorge Gandía, Daniela C G Bertarelli, Masahiko Watanabe, Carme Lluís, Rafael Franco, Sergi Ferré, Rafael Luján, Francisco Ciruela. J Neurochem 2009
Nuria Cabello, Jorge Gandía, Daniela C G Bertarelli, Masahiko Watanabe, Carme Lluís, Rafael Franco, Sergi Ferré, Rafael Luján, Francisco Ciruela. J Neurochem 2009
12
Metabotropic glutamate receptors: from the workbench to the bedside.
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
12
The dynamic process of β(2)-adrenergic receptor activation.
Rie Nygaard, Yaozhong Zou, Ron O Dror, Thomas J Mildorf, Daniel H Arlow, Aashish Manglik, Albert C Pan, Corey W Liu, Juan José Fung, Michael P Bokoch,[...]. Cell 2013
Rie Nygaard, Yaozhong Zou, Ron O Dror, Thomas J Mildorf, Daniel H Arlow, Aashish Manglik, Albert C Pan, Corey W Liu, Juan José Fung, Michael P Bokoch,[...]. Cell 2013
12
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Vadim Cherezov, Daniel M Rosenbaum, Michael A Hanson, Søren G F Rasmussen, Foon Sun Thian, Tong Sun Kobilka, Hee-Jung Choi, Peter Kuhn, William I Weis, Brian K Kobilka,[...]. Science 2007
Vadim Cherezov, Daniel M Rosenbaum, Michael A Hanson, Søren G F Rasmussen, Foon Sun Thian, Tong Sun Kobilka, Hee-Jung Choi, Peter Kuhn, William I Weis, Brian K Kobilka,[...]. Science 2007
11
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Beili Wu, Ellen Y T Chien, Clifford D Mol, Gustavo Fenalti, Wei Liu, Vsevolod Katritch, Ruben Abagyan, Alexei Brooun, Peter Wells, F Christopher Bi,[...]. Science 2010
Beili Wu, Ellen Y T Chien, Clifford D Mol, Gustavo Fenalti, Wei Liu, Vsevolod Katritch, Ruben Abagyan, Alexei Brooun, Peter Wells, F Christopher Bi,[...]. Science 2010
11
Molecular signatures of G-protein-coupled receptors.
A J Venkatakrishnan, Xavier Deupi, Guillaume Lebon, Christopher G Tate, Gebhard F Schertler, M Madan Babu. Nature 2013
A J Venkatakrishnan, Xavier Deupi, Guillaume Lebon, Christopher G Tate, Gebhard F Schertler, M Madan Babu. Nature 2013
11
The structure and function of G-protein-coupled receptors.
Daniel M Rosenbaum, Søren G F Rasmussen, Brian K Kobilka. Nature 2009
Daniel M Rosenbaum, Søren G F Rasmussen, Brian K Kobilka. Nature 2009
10
Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.
Carsten Brock, Nadia Oueslati, Stéphan Soler, Laure Boudier, Philippe Rondard, Jean-Philippe Pin. J Biol Chem 2007
Carsten Brock, Nadia Oueslati, Stéphan Soler, Laure Boudier, Philippe Rondard, Jean-Philippe Pin. J Biol Chem 2007
11
The complexity of their activation mechanism opens new possibilities for the modulation of mGlu and GABAB class C G protein-coupled receptors.
Philippe Rondard, Cyril Goudet, Julie Kniazeff, Jean-Philippe Pin, Laurent Prézeau. Neuropharmacology 2011
Philippe Rondard, Cyril Goudet, Julie Kniazeff, Jean-Philippe Pin, Laurent Prézeau. Neuropharmacology 2011
18
Pharmacology and functions of metabotropic glutamate receptors.
P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
10
Cooperative signaling between homodimers of metabotropic glutamate receptors 1 and 5.
Tatyana N Sevastyanova, Paul J Kammermeier. Mol Pharmacol 2014
Tatyana N Sevastyanova, Paul J Kammermeier. Mol Pharmacol 2014
38
Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.
John A Christopher, Zoltán Orgován, Miles Congreve, Andrew S Doré, James C Errey, Fiona H Marshall, Jonathan S Mason, Krzysztof Okrasa, Prakash Rucktooa, Maria J Serrano-Vega,[...]. J Med Chem 2019
John A Christopher, Zoltán Orgován, Miles Congreve, Andrew S Doré, James C Errey, Fiona H Marshall, Jonathan S Mason, Krzysztof Okrasa, Prakash Rucktooa, Maria J Serrano-Vega,[...]. J Med Chem 2019
22
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.