Tania Tahtouh, Jonathan M Elkins, Panagis Filippakopoulos, Meera Soundararajan, Guillaume Burgy, Emilie Durieu, Claude Cochet, Ralf S Schmid, Donald C Lo, Florent Delhommel, Anselm E Oberholzer, Laurence H Pearl, François Carreaux, Jean-Pierre Bazureau, Stefan Knapp, Laurent Meijer. J Med Chem 2012
Times Cited: 141
Times Cited: 141
Times Cited
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Similarity
Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.
Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya,[...]. Nat Commun 2010
Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya,[...]. Nat Commun 2010
48
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Mansour Debdab, François Carreaux, Steven Renault, Meera Soundararajan, Oleg Fedorov, Panagis Filippakopoulos, Olivier Lozach, Lucie Babault, Tania Tahtouh, Blandine Baratte,[...]. J Med Chem 2011
Mansour Debdab, François Carreaux, Steven Renault, Meera Soundararajan, Oleg Fedorov, Panagis Filippakopoulos, Olivier Lozach, Lucie Babault, Tania Tahtouh, Blandine Baratte,[...]. J Med Chem 2011
35
Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?
Breland Smith, Federico Medda, Vijay Gokhale, Travis Dunckley, Christopher Hulme. ACS Chem Neurosci 2012
Breland Smith, Federico Medda, Vijay Gokhale, Travis Dunckley, Christopher Hulme. ACS Chem Neurosci 2012
33
The role of DYRK1A in neurodegenerative diseases.
Jerzy Wegiel, Cheng-Xin Gong, Yu-Wen Hwang. FEBS J 2011
Jerzy Wegiel, Cheng-Xin Gong, Yu-Wen Hwang. FEBS J 2011
30
The specificities of protein kinase inhibitors: an update.
Jenny Bain, Hilary McLauchlan, Matthew Elliott, Philip Cohen. Biochem J 2003
Jenny Bain, Hilary McLauchlan, Matthew Elliott, Philip Cohen. Biochem J 2003
28
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
27
10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.
Hannes Falke, Apirat Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Samira Abu Jhaisha, Walter Becker, Peter G Jones, Lutz Preu, Knut Baumann,[...]. J Med Chem 2015
Hannes Falke, Apirat Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Samira Abu Jhaisha, Walter Becker, Peter G Jones, Lutz Preu, Knut Baumann,[...]. J Med Chem 2015
45
Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.
Francis Giraud, Georges Alves, Eric Debiton, Lionel Nauton, Vincent Théry, Emilie Durieu, Yoan Ferandin, Olivier Lozach, Laurent Meijer, Fabrice Anizon,[...]. J Med Chem 2011
Francis Giraud, Georges Alves, Eric Debiton, Lionel Nauton, Vincent Théry, Emilie Durieu, Yoan Ferandin, Olivier Lozach, Laurent Meijer, Fabrice Anizon,[...]. J Med Chem 2011
30
Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing.
Oleg Fedorov, Kilian Huber, Andreas Eisenreich, Panagis Filippakopoulos, Oliver King, Alex N Bullock, Damian Szklarczyk, Lars J Jensen, Doriano Fabbro, Jörg Trappe,[...]. Chem Biol 2011
Oleg Fedorov, Kilian Huber, Andreas Eisenreich, Panagis Filippakopoulos, Oliver King, Alex N Bullock, Damian Szklarczyk, Lars J Jensen, Doriano Fabbro, Jörg Trappe,[...]. Chem Biol 2011
23
A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard,[...]. J Neurochem 2015
Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard,[...]. J Neurochem 2015
29
DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Soo-Ryoon Ryoo, Hey Kyeong Jeong, Chinzorig Radnaabazar, Jin-Ju Yoo, Hyun-Jeong Cho, Hye-Won Lee, In-Sook Kim, Young-Hee Cheon, Young Soo Ahn, Sul-Hee Chung,[...]. J Biol Chem 2007
Soo-Ryoon Ryoo, Hey Kyeong Jeong, Chinzorig Radnaabazar, Jin-Ju Yoo, Hyun-Jeong Cho, Hye-Won Lee, In-Sook Kim, Young-Hee Cheon, Young Soo Ahn, Sul-Hee Chung,[...]. J Biol Chem 2007
22
22
Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice.
Gaëlle Naert, Valentine Ferré, Johann Meunier, Emeline Keller, Susanna Malmström, Laurent Givalois, François Carreaux, Jean-Pierre Bazureau, Tangui Maurice. Eur Neuropsychopharmacol 2015
Gaëlle Naert, Valentine Ferré, Johann Meunier, Emeline Keller, Susanna Malmström, Laurent Givalois, François Carreaux, Jean-Pierre Bazureau, Tangui Maurice. Eur Neuropsychopharmacol 2015
59
Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, You-Qing Zhang, Anwesh Kamireddy, Austin Swafford, Andrew F Powers, John Walker,[...]. Nat Commun 2015
Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, You-Qing Zhang, Anwesh Kamireddy, Austin Swafford, Andrew F Powers, John Walker,[...]. Nat Commun 2015
22
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
Andrew S Rosenthal, Cordelle Tanega, Min Shen, Bryan T Mott, James M Bougie, Dac-Trung Nguyen, Tom Misteli, Douglas S Auld, David J Maloney, Craig J Thomas. Bioorg Med Chem Lett 2011
Andrew S Rosenthal, Cordelle Tanega, Min Shen, Bryan T Mott, James M Bougie, Dac-Trung Nguyen, Tom Misteli, Douglas S Auld, David J Maloney, Craig J Thomas. Bioorg Med Chem Lett 2011
38
Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M Burns, Tamara J Gilbert, David E Olson,[...]. Diabetes 2016
Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M Burns, Tamara J Gilbert, David E Olson,[...]. Diabetes 2016
21
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata,[...]. Hum Mol Genet 2007
Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata,[...]. Hum Mol Genet 2007
19
DYRK1A: a potential drug target for multiple Down syndrome neuropathologies.
Walter Becker, Ulf Soppa, Francisco J Tejedor. CNS Neurol Disord Drug Targets 2014
Walter Becker, Ulf Soppa, Francisco J Tejedor. CNS Neurol Disord Drug Targets 2014
28
The selectivity of protein kinase inhibitors: a further update.
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
19
Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.
Thu Lan Nguyen, Corinne Fruit, Yann Hérault, Laurent Meijer, Thierry Besson. Expert Opin Ther Pat 2017
Thu Lan Nguyen, Corinne Fruit, Yann Hérault, Laurent Meijer, Thierry Besson. Expert Opin Ther Pat 2017
52
A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Ocaña,[...]. Nat Med 2015
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Ocaña,[...]. Nat Med 2015
19
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung,[...]. J Neurochem 2008
Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung,[...]. J Neurochem 2008
18
β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites.
Danielle Frost, Bessie Meechoovet, Tong Wang, Stephen Gately, Marco Giorgetti, Irina Shcherbakova, Travis Dunckley. PLoS One 2011
Danielle Frost, Bessie Meechoovet, Tong Wang, Stephen Gately, Marco Giorgetti, Irina Shcherbakova, Travis Dunckley. PLoS One 2011
18
Development of DANDYs, new 3,5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity.
Stéphanie Gourdain, Julien Dairou, Clément Denhez, Linh Chi Bui, Fernando Rodrigues-Lima, Nathalie Janel, Jean M Delabar, Kevin Cariou, Robert H Dodd. J Med Chem 2013
Stéphanie Gourdain, Julien Dairou, Clément Denhez, Linh Chi Bui, Fernando Rodrigues-Lima, Nathalie Janel, Jean M Delabar, Kevin Cariou, Robert H Dodd. J Med Chem 2013
47
Hydroxybenzothiophene Ketones Are Efficient Pre-mRNA Splicing Modulators Due to Dual Inhibition of Dyrk1A and Clk1/4.
Christian Schmitt, Parisa Miralinaghi, Marica Mariano, Rolf W Hartmann, Matthias Engel. ACS Med Chem Lett 2014
Christian Schmitt, Parisa Miralinaghi, Marica Mariano, Rolf W Hartmann, Matthias Engel. ACS Med Chem Lett 2014
48
DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles.
Sergi Aranda, Ariadna Laguna, Susana de la Luna. FASEB J 2011
Sergi Aranda, Ariadna Laguna, Susana de la Luna. FASEB J 2011
18
DYRK1A kinase inhibitors with emphasis on cancer.
A Ionescu, F Dufrasne, M Gelbcke, I Jabin, R Kiss, D Lamoral-Theys. Mini Rev Med Chem 2012
A Ionescu, F Dufrasne, M Gelbcke, I Jabin, R Kiss, D Lamoral-Theys. Mini Rev Med Chem 2012
35
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models.
Isidro Ferrer, Marta Barrachina, Berta Puig, M Martínez de Lagrán, Eulalia Martí, Jesús Avila, Mara Dierssen. Neurobiol Dis 2005
Isidro Ferrer, Marta Barrachina, Berta Puig, M Martínez de Lagrán, Eulalia Martí, Jesús Avila, Mara Dierssen. Neurobiol Dis 2005
17
Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
17
Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues: a novel DYRK1A inhibitor class.
Cleopatra Neagoie, Emeline Vedrenne, Frédéric Buron, Jean-Yves Mérour, Sorin Rosca, Stéphane Bourg, Olivier Lozach, Laurent Meijer, Brigitte Baldeyrou, Amelie Lansiaux,[...]. Eur J Med Chem 2012
Cleopatra Neagoie, Emeline Vedrenne, Frédéric Buron, Jean-Yves Mérour, Sorin Rosca, Stéphane Bourg, Olivier Lozach, Laurent Meijer, Brigitte Baldeyrou, Amelie Lansiaux,[...]. Eur J Med Chem 2012
31
Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.
Aude Echalier, Karima Bettayeb, Yoan Ferandin, Olivier Lozach, Monique Clément, Annie Valette, François Liger, Bernard Marquet, Jonathan C Morris, Jane A Endicott,[...]. J Med Chem 2008
Aude Echalier, Karima Bettayeb, Yoan Ferandin, Olivier Lozach, Monique Clément, Annie Valette, François Liger, Bernard Marquet, Jonathan C Morris, Jane A Endicott,[...]. J Med Chem 2008
16
Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome.
Jianhua Shi, Tianyi Zhang, Chunlei Zhou, Muhammad Omar Chohan, Xiaosong Gu, Jerzy Wegiel, Jianhua Zhou, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal,[...]. J Biol Chem 2008
Jianhua Shi, Tianyi Zhang, Chunlei Zhou, Muhammad Omar Chohan, Xiaosong Gu, Jerzy Wegiel, Jianhua Zhou, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal,[...]. J Biol Chem 2008
16
Pyrido[2,3-d]pyrimidines: discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors.
Kevin Anderson, Yi Chen, Zhi Chen, Romyr Dominique, Kelli Glenn, Yang He, Cheryl Janson, Kin-Chun Luk, Christine Lukacs, Ann Polonskaia,[...]. Bioorg Med Chem Lett 2013
Kevin Anderson, Yi Chen, Zhi Chen, Romyr Dominique, Kelli Glenn, Yang He, Cheryl Janson, Kin-Chun Luk, Christine Lukacs, Ann Polonskaia,[...]. Bioorg Med Chem Lett 2013
44
Human CDC2-like kinase 1 (CLK1): a novel target for Alzheimer's disease.
Princi Jain, Chandrabose Karthikeyan, N S Hari Narayana Moorthy, Digambar Kumar Waiker, Arvind Kumar Jain, Piyush Trivedi. Curr Drug Targets 2014
Princi Jain, Chandrabose Karthikeyan, N S Hari Narayana Moorthy, Digambar Kumar Waiker, Arvind Kumar Jain, Piyush Trivedi. Curr Drug Targets 2014
25
DYRK1A inhibition as potential treatment for Alzheimer's disease.
Silvia Stotani, Fabrizio Giordanetto, Federico Medda. Future Med Chem 2016
Silvia Stotani, Fabrizio Giordanetto, Federico Medda. Future Med Chem 2016
42
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome.
Arnaud Duchon, Yann Herault. Front Behav Neurosci 2016
Arnaud Duchon, Yann Herault. Front Behav Neurosci 2016
16
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase.
Y L Woods, P Cohen, W Becker, R Jakes, M Goedert, X Wang, C G Proud. Biochem J 2001
Y L Woods, P Cohen, W Becker, R Jakes, M Goedert, X Wang, C G Proud. Biochem J 2001
15
Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
Young Shin Ryu, So Young Park, Min-Su Jung, Song-Hee Yoon, Mi-Yang Kwen, Sun-Young Lee, Sun-Hee Choi, Chinzorig Radnaabazar, Mi-Kyoung Kim, Hangun Kim,[...]. J Neurochem 2010
Young Shin Ryu, So Young Park, Min-Su Jung, Song-Hee Yoon, Mi-Yang Kwen, Sun-Young Lee, Sun-Hee Choi, Chinzorig Radnaabazar, Mi-Kyoung Kim, Hangun Kim,[...]. J Neurochem 2010
23
Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors.
Christian Schmitt, Dagmar Kail, Marica Mariano, Martin Empting, Nadja Weber, Tamara Paul, Rolf W Hartmann, Matthias Engel. PLoS One 2014
Christian Schmitt, Dagmar Kail, Marica Mariano, Martin Empting, Nadja Weber, Tamara Paul, Rolf W Hartmann, Matthias Engel. PLoS One 2014
44
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
Fei Liu, Zhihou Liang, Jerzy Wegiel, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Narayan Ramakrishna, Cheng-Xin Gong. FASEB J 2008
Fei Liu, Zhihou Liang, Jerzy Wegiel, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Narayan Ramakrishna, Cheng-Xin Gong. FASEB J 2008
15
Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker. PLoS One 2015
Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker. PLoS One 2015
40
Manipulation of alternative splicing by a newly developed inhibitor of Clks.
Michiko Muraki, Bisei Ohkawara, Takamitsu Hosoya, Hiroshi Onogi, Jun Koizumi, Tomonobu Koizumi, Kengo Sumi, Jun-ichiro Yomoda, Michael V Murray, Hiroshi Kimura,[...]. J Biol Chem 2004
Michiko Muraki, Bisei Ohkawara, Takamitsu Hosoya, Hiroshi Onogi, Jun Koizumi, Tomonobu Koizumi, Kengo Sumi, Jun-ichiro Yomoda, Michael V Murray, Hiroshi Kimura,[...]. J Biol Chem 2004
15
Selective inhibition of the kinase DYRK1A by targeting its folding process.
Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka,[...]. Nat Commun 2016
Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka,[...]. Nat Commun 2016
30
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
Dnyandev B Jarhad, Karishma K Mashelkar, Hong-Rae Kim, Minsoo Noh, Lak Shin Jeong. J Med Chem 2018
Dnyandev B Jarhad, Karishma K Mashelkar, Hong-Rae Kim, Minsoo Noh, Lak Shin Jeong. J Med Chem 2018
28
Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.
Fayçal Guedj, Catherine Sébrié, Isabelle Rivals, Aurelie Ledru, Evelyne Paly, Jean C Bizot, Desmond Smith, Edward Rubin, Brigitte Gillet, Mariona Arbones,[...]. PLoS One 2009
Fayçal Guedj, Catherine Sébrié, Isabelle Rivals, Aurelie Ledru, Evelyne Paly, Jean C Bizot, Desmond Smith, Edward Rubin, Brigitte Gillet, Mariona Arbones,[...]. PLoS One 2009
14
Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
Rafael De la Torre, Susana De Sola, Meritxell Pons, Arnaud Duchon, María Martínez de Lagran, Magí Farré, Montserrat Fitó, Bessy Benejam, Klaus Langohr, Joan Rodriguez,[...]. Mol Nutr Food Res 2014
Rafael De la Torre, Susana De Sola, Meritxell Pons, Arnaud Duchon, María Martínez de Lagran, Magí Farré, Montserrat Fitó, Bessy Benejam, Klaus Langohr, Joan Rodriguez,[...]. Mol Nutr Food Res 2014
14
DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis.
P Fernández-Martínez, C Zahonero, P Sánchez-Gómez. Mol Cell Oncol 2015
P Fernández-Martínez, C Zahonero, P Sánchez-Gómez. Mol Cell Oncol 2015
22
Dyrk1 inhibition improves Alzheimer's disease-like pathology.
Caterina Branca, Darren M Shaw, Ramona Belfiore, Vijay Gokhale, Arthur Y Shaw, Christopher Foley, Breland Smith, Christopher Hulme, Travis Dunckley, Bessie Meechoovet,[...]. Aging Cell 2017
Caterina Branca, Darren M Shaw, Ramona Belfiore, Vijay Gokhale, Arthur Y Shaw, Christopher Foley, Breland Smith, Christopher Hulme, Travis Dunckley, Bessie Meechoovet,[...]. Aging Cell 2017
25
Meridianins, a new family of protein kinase inhibitors isolated from the ascidian Aplidium meridianum.
Marie Gompel, Maryse Leost, Elisa Bal De Kier Joffe, Lydia Puricelli, Laura Hernandez Franco, Jorge Palermo, Laurent Meijer. Bioorg Med Chem Lett 2004
Marie Gompel, Maryse Leost, Elisa Bal De Kier Joffe, Lydia Puricelli, Laura Hernandez Franco, Jorge Palermo, Laurent Meijer. Bioorg Med Chem Lett 2004
13
Function and regulation of Dyrk1A: towards understanding Down syndrome.
Joongkyu Park, Woo-Joo Song, Kwang Chul Chung. Cell Mol Life Sci 2009
Joongkyu Park, Woo-Joo Song, Kwang Chul Chung. Cell Mol Life Sci 2009
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.