A citation-based method for searching scientific literature

Tania Tahtouh, Jonathan M Elkins, Panagis Filippakopoulos, Meera Soundararajan, Guillaume Burgy, Emilie Durieu, Claude Cochet, Ralf S Schmid, Donald C Lo, Florent Delhommel, Anselm E Oberholzer, Laurence H Pearl, François Carreaux, Jean-Pierre Bazureau, Stefan Knapp, Laurent Meijer. J Med Chem 2012
Times Cited: 141







List of co-cited articles
948 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.
Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya,[...]. Nat Commun 2010
183
48

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Mansour Debdab, François Carreaux, Steven Renault, Meera Soundararajan, Oleg Fedorov, Panagis Filippakopoulos, Olivier Lozach, Lucie Babault, Tania Tahtouh, Blandine Baratte,[...]. J Med Chem 2011
97
35


The role of DYRK1A in neurodegenerative diseases.
Jerzy Wegiel, Cheng-Xin Gong, Yu-Wen Hwang. FEBS J 2011
170
30

The specificities of protein kinase inhibitors: an update.
Jenny Bain, Hilary McLauchlan, Matthew Elliott, Philip Cohen. Biochem J 2003
28

Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
169
27

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.
Hannes Falke, Apirat Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Samira Abu Jhaisha, Walter Becker, Peter G Jones, Lutz Preu, Knut Baumann,[...]. J Med Chem 2015
57
45

Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.
Francis Giraud, Georges Alves, Eric Debiton, Lionel Nauton, Vincent Théry, Emilie Durieu, Yoan Ferandin, Olivier Lozach, Laurent Meijer, Fabrice Anizon,[...]. J Med Chem 2011
78
30

Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing.
Oleg Fedorov, Kilian Huber, Andreas Eisenreich, Panagis Filippakopoulos, Oliver King, Alex N Bullock, Damian Szklarczyk, Lars J Jensen, Doriano Fabbro, Jörg Trappe,[...]. Chem Biol 2011
145
23

A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard,[...]. J Neurochem 2015
78
29

DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Soo-Ryoon Ryoo, Hey Kyeong Jeong, Chinzorig Radnaabazar, Jin-Ju Yoo, Hyun-Jeong Cho, Hye-Won Lee, In-Sook Kim, Young-Hee Cheon, Young Soo Ahn, Sul-Hee Chung,[...]. J Biol Chem 2007
172
22

Activation, regulation, and inhibition of DYRK1A.
Walter Becker, Wolfgang Sippl. FEBS J 2011
142
22

Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice.
Gaëlle Naert, Valentine Ferré, Johann Meunier, Emeline Keller, Susanna Malmström, Laurent Givalois, François Carreaux, Jean-Pierre Bazureau, Tangui Maurice. Eur Neuropsychopharmacol 2015
37
59

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, You-Qing Zhang, Anwesh Kamireddy, Austin Swafford, Andrew F Powers, John Walker,[...]. Nat Commun 2015
128
22

Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
Andrew S Rosenthal, Cordelle Tanega, Min Shen, Bryan T Mott, James M Bougie, Dac-Trung Nguyen, Tom Misteli, Douglas S Auld, David J Maloney, Craig J Thomas. Bioorg Med Chem Lett 2011
55
38

Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M Burns, Tamara J Gilbert, David E Olson,[...]. Diabetes 2016
119
21

The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata,[...]. Hum Mol Genet 2007
184
19

DYRK1A: a potential drug target for multiple Down syndrome neuropathologies.
Walter Becker, Ulf Soppa, Francisco J Tejedor. CNS Neurol Disord Drug Targets 2014
67
28

The selectivity of protein kinase inhibitors: a further update.
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
19

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.
Thu Lan Nguyen, Corinne Fruit, Yann Hérault, Laurent Meijer, Thierry Besson. Expert Opin Ther Pat 2017
36
52

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Ocaña,[...]. Nat Med 2015
235
19

Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung,[...]. J Neurochem 2008
140
18

β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites.
Danielle Frost, Bessie Meechoovet, Tong Wang, Stephen Gately, Marco Giorgetti, Irina Shcherbakova, Travis Dunckley. PLoS One 2011
107
18

Development of DANDYs, new 3,5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity.
Stéphanie Gourdain, Julien Dairou, Clément Denhez, Linh Chi Bui, Fernando Rodrigues-Lima, Nathalie Janel, Jean M Delabar, Kevin Cariou, Robert H Dodd. J Med Chem 2013
38
47

Hydroxybenzothiophene Ketones Are Efficient Pre-mRNA Splicing Modulators Due to Dual Inhibition of Dyrk1A and Clk1/4.
Christian Schmitt, Parisa Miralinaghi, Marica Mariano, Rolf W Hartmann, Matthias Engel. ACS Med Chem Lett 2014
37
48


DYRK1A kinase inhibitors with emphasis on cancer.
A Ionescu, F Dufrasne, M Gelbcke, I Jabin, R Kiss, D Lamoral-Theys. Mini Rev Med Chem 2012
51
35

Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models.
Isidro Ferrer, Marta Barrachina, Berta Puig, M Martínez de Lagrán, Eulalia Martí, Jesús Avila, Mara Dierssen. Neurobiol Dis 2005
123
17

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
97
17

Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues: a novel DYRK1A inhibitor class.
Cleopatra Neagoie, Emeline Vedrenne, Frédéric Buron, Jean-Yves Mérour, Sorin Rosca, Stéphane Bourg, Olivier Lozach, Laurent Meijer, Brigitte Baldeyrou, Amelie Lansiaux,[...]. Eur J Med Chem 2012
54
31

Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.
Aude Echalier, Karima Bettayeb, Yoan Ferandin, Olivier Lozach, Monique Clément, Annie Valette, François Liger, Bernard Marquet, Jonathan C Morris, Jane A Endicott,[...]. J Med Chem 2008
107
16

Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome.
Jianhua Shi, Tianyi Zhang, Chunlei Zhou, Muhammad Omar Chohan, Xiaosong Gu, Jerzy Wegiel, Jianhua Zhou, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal,[...]. J Biol Chem 2008
115
16

Pyrido[2,3-d]pyrimidines: discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors.
Kevin Anderson, Yi Chen, Zhi Chen, Romyr Dominique, Kelli Glenn, Yang He, Cheryl Janson, Kin-Chun Luk, Christine Lukacs, Ann Polonskaia,[...]. Bioorg Med Chem Lett 2013
36
44

Human CDC2-like kinase 1 (CLK1): a novel target for Alzheimer's disease.
Princi Jain, Chandrabose Karthikeyan, N S Hari Narayana Moorthy, Digambar Kumar Waiker, Arvind Kumar Jain, Piyush Trivedi. Curr Drug Targets 2014
63
25

DYRK1A inhibition as potential treatment for Alzheimer's disease.
Silvia Stotani, Fabrizio Giordanetto, Federico Medda. Future Med Chem 2016
38
42



Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
Young Shin Ryu, So Young Park, Min-Su Jung, Song-Hee Yoon, Mi-Yang Kwen, Sun-Young Lee, Sun-Hee Choi, Chinzorig Radnaabazar, Mi-Kyoung Kim, Hangun Kim,[...]. J Neurochem 2010
65
23

Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors.
Christian Schmitt, Dagmar Kail, Marica Mariano, Martin Empting, Nadja Weber, Tamara Paul, Rolf W Hartmann, Matthias Engel. PLoS One 2014
34
44

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
Fei Liu, Zhihou Liang, Jerzy Wegiel, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Narayan Ramakrishna, Cheng-Xin Gong. FASEB J 2008
162
15

Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker. PLoS One 2015
37
40

Manipulation of alternative splicing by a newly developed inhibitor of Clks.
Michiko Muraki, Bisei Ohkawara, Takamitsu Hosoya, Hiroshi Onogi, Jun Koizumi, Tomonobu Koizumi, Kengo Sumi, Jun-ichiro Yomoda, Michael V Murray, Hiroshi Kimura,[...]. J Biol Chem 2004
225
15

Selective inhibition of the kinase DYRK1A by targeting its folding process.
Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka,[...]. Nat Commun 2016
49
30

Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
Dnyandev B Jarhad, Karishma K Mashelkar, Hong-Rae Kim, Minsoo Noh, Lak Shin Jeong. J Med Chem 2018
53
28

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.
Fayçal Guedj, Catherine Sébrié, Isabelle Rivals, Aurelie Ledru, Evelyne Paly, Jean C Bizot, Desmond Smith, Edward Rubin, Brigitte Gillet, Mariona Arbones,[...]. PLoS One 2009
142
14

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
Rafael De la Torre, Susana De Sola, Meritxell Pons, Arnaud Duchon, María Martínez de Lagran, Magí Farré, Montserrat Fitó, Bessy Benejam, Klaus Langohr, Joan Rodriguez,[...]. Mol Nutr Food Res 2014
178
14

DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis.
P Fernández-Martínez, C Zahonero, P Sánchez-Gómez. Mol Cell Oncol 2015
61
22

Dyrk1 inhibition improves Alzheimer's disease-like pathology.
Caterina Branca, Darren M Shaw, Ramona Belfiore, Vijay Gokhale, Arthur Y Shaw, Christopher Foley, Breland Smith, Christopher Hulme, Travis Dunckley, Bessie Meechoovet,[...]. Aging Cell 2017
56
25

Meridianins, a new family of protein kinase inhibitors isolated from the ascidian Aplidium meridianum.
Marie Gompel, Maryse Leost, Elisa Bal De Kier Joffe, Lydia Puricelli, Laura Hernandez Franco, Jorge Palermo, Laurent Meijer. Bioorg Med Chem Lett 2004
129
13

Function and regulation of Dyrk1A: towards understanding Down syndrome.
Joongkyu Park, Woo-Joo Song, Kwang Chul Chung. Cell Mol Life Sci 2009
137
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.