Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen, Juha M Yrjänheikki, Bruno Buisson, David Howland, Vahri Beaumont, Ignacio Munoz-Sanjuan, Larry C Park. PLoS One 2012
Times Cited: 147
Times Cited: 147
Times Cited
Times Co-cited
Similarity
Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
72
62
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
44
Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
30
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
26
Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease.
Tim Indersmitten, Conny H Tran, Carlos Cepeda, Michael S Levine. J Neurophysiol 2015
Tim Indersmitten, Conny H Tran, Carlos Cepeda, Michael S Levine. J Neurophysiol 2015
56
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
26
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
23
Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
23
Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease.
Gaynor A Smith, Emily M Rocha, Jesse R McLean, Melissa A Hayes, Sarah C Izen, Ole Isacson, Penelope J Hallett. Hum Mol Genet 2014
Gaynor A Smith, Emily M Rocha, Jesse R McLean, Melissa A Hayes, Sarah C Izen, Ole Isacson, Penelope J Hallett. Hum Mol Genet 2014
35
Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
21
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
19
Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
18
Differential loss of striatal projection neurons in Huntington disease.
A Reiner, R L Albin, K D Anderson, C J D'Amato, J B Penney, A B Young. Proc Natl Acad Sci U S A 1988
A Reiner, R L Albin, K D Anderson, C J D'Amato, J B Penney, A B Young. Proc Natl Acad Sci U S A 1988
18
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.
L A Raymond, V M André, C Cepeda, C M Gladding, A J Milnerwood, M S Levine. Neuroscience 2011
L A Raymond, V M André, C Cepeda, C M Gladding, A J Milnerwood, M S Levine. Neuroscience 2011
17
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
17
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
16
Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington's Disease.
Qi Peng, Bin Wu, Mali Jiang, Jing Jin, Zhipeng Hou, Jennifer Zheng, Jiangyang Zhang, Wenzhen Duan. PLoS One 2016
Qi Peng, Bin Wu, Mali Jiang, Jing Jin, Zhipeng Hou, Jennifer Zheng, Jiangyang Zhang, Wenzhen Duan. PLoS One 2016
53
Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
15
Multiple sources of striatal inhibition are differentially affected in Huntington's disease mouse models.
Carlos Cepeda, Laurie Galvan, Sandra M Holley, Shilpa P Rao, Véronique M André, Elian P Botelho, Jane Y Chen, Joseph B Watson, Karl Deisseroth, Michael S Levine. J Neurosci 2013
Carlos Cepeda, Laurie Galvan, Sandra M Holley, Shilpa P Rao, Véronique M André, Elian P Botelho, Jane Y Chen, Joseph B Watson, Karl Deisseroth, Michael S Levine. J Neurosci 2013
18
The corticostriatal pathway in Huntington's disease.
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
15
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
15
Alterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease.
Damian M Cummings, Véronique M André, Besim O Uzgil, Steven M Gee, Yvette E Fisher, Carlos Cepeda, Michael S Levine. J Neurosci 2009
Damian M Cummings, Véronique M André, Besim O Uzgil, Steven M Gee, Yvette E Fisher, Carlos Cepeda, Michael S Levine. J Neurosci 2009
14
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.
Carlos Cepeda, Raymond S Hurst, Christopher R Calvert, Elizabeth Hernández-Echeagaray, Oanh K Nguyen, Emily Jocoy, Lindsey J Christian, Marjorie A Ariano, Michael S Levine. J Neurosci 2003
Carlos Cepeda, Raymond S Hurst, Christopher R Calvert, Elizabeth Hernández-Echeagaray, Oanh K Nguyen, Emily Jocoy, Lindsey J Christian, Marjorie A Ariano, Michael S Levine. J Neurosci 2003
14
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
V C Wheeler, J K White, C A Gutekunst, V Vrbanac, M Weaver, X J Li, S H Li, H Yi, J P Vonsattel, J F Gusella,[...]. Hum Mol Genet 2000
V C Wheeler, J K White, C A Gutekunst, V Vrbanac, M Weaver, X J Li, S H Li, H Yi, J P Vonsattel, J F Gusella,[...]. Hum Mol Genet 2000
14
Choosing an animal model for the study of Huntington's disease.
Mahmoud A Pouladi, A Jennifer Morton, Michael R Hayden. Nat Rev Neurosci 2013
Mahmoud A Pouladi, A Jennifer Morton, Michael R Hayden. Nat Rev Neurosci 2013
13
Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures.
H Diana Rosas, David S Tuch, Nathanael D Hevelone, Alexandra K Zaleta, Mark Vangel, Steven M Hersch, David H Salat. Mov Disord 2006
H Diana Rosas, David S Tuch, Nathanael D Hevelone, Alexandra K Zaleta, Mark Vangel, Steven M Hersch, David H Salat. Mov Disord 2006
13
Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease.
Prasad R Joshi, Nan-Ping Wu, Véronique M André, Damian M Cummings, Carlos Cepeda, John A Joyce, Jeffrey B Carroll, Blair R Leavitt, Michael R Hayden, Michael S Levine,[...]. J Neurosci 2009
Prasad R Joshi, Nan-Ping Wu, Véronique M André, Damian M Cummings, Carlos Cepeda, John A Joyce, Jeffrey B Carroll, Blair R Leavitt, Michael R Hayden, Michael S Levine,[...]. J Neurosci 2009
13
Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease.
Joshua L Plotkin, Michelle Day, Jayms D Peterson, Zhong Xie, Geraldine J Kress, Igor Rafalovich, Jyothisri Kondapalli, Tracy S Gertler, Marc Flajolet, Paul Greengard,[...]. Neuron 2014
Joshua L Plotkin, Michelle Day, Jayms D Peterson, Zhong Xie, Geraldine J Kress, Igor Rafalovich, Jyothisri Kondapalli, Tracy S Gertler, Marc Flajolet, Paul Greengard,[...]. Neuron 2014
13
Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease.
Mary Y Heng, Sara J Tallaksen-Greene, Peter J Detloff, Roger L Albin. J Neurosci 2007
Mary Y Heng, Sara J Tallaksen-Greene, Peter J Detloff, Roger L Albin. J Neurosci 2007
13
Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study.
Nikisha Carty, Nadège Berson, Karsten Tillack, Christina Thiede, Diana Scholz, Karsten Kottig, Yalda Sedaghat, Christina Gabrysiak, George Yohrling, Heinz von der Kammer,[...]. PLoS One 2015
Nikisha Carty, Nadège Berson, Karsten Tillack, Christina Thiede, Diana Scholz, Karsten Kottig, Yalda Sedaghat, Christina Gabrysiak, George Yohrling, Heinz von der Kammer,[...]. PLoS One 2015
37
Differential electrophysiological changes in striatal output neurons in Huntington's disease.
Véronique M André, Carlos Cepeda, Yvette E Fisher, My Huynh, Nora Bardakjian, Sumedha Singh, X William Yang, Michael S Levine. J Neurosci 2011
Véronique M André, Carlos Cepeda, Yvette E Fisher, My Huynh, Nora Bardakjian, Sumedha Singh, X William Yang, Michael S Levine. J Neurosci 2011
13
Genetic mouse models of Huntington's disease: focus on electrophysiological mechanisms.
Carlos Cepeda, Damian M Cummings, Véronique M André, Sandra M Holley, Michael S Levine. ASN Neuro 2010
Carlos Cepeda, Damian M Cummings, Véronique M André, Sandra M Holley, Michael S Levine. ASN Neuro 2010
19
Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
12
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
12
Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
12
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
12
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
12
Dysregulated information processing by medium spiny neurons in striatum of freely behaving mouse models of Huntington's disease.
Benjamin R Miller, Adam G Walker, Anand S Shah, Scott J Barton, George V Rebec. J Neurophysiol 2008
Benjamin R Miller, Adam G Walker, Anand S Shah, Scott J Barton, George V Rebec. J Neurophysiol 2008
13
The Neuropathology of Huntington's Disease.
Henry J Waldvogel, Eric H Kim, Lynette J Tippett, Jean-Paul G Vonsattel, Richard L M Faull. Curr Top Behav Neurosci 2015
Henry J Waldvogel, Eric H Kim, Lynette J Tippett, Jean-Paul G Vonsattel, Richard L M Faull. Curr Top Behav Neurosci 2015
15
Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis.
H D Rosas, W J Koroshetz, Y I Chen, C Skeuse, M Vangel, M E Cudkowicz, K Caplan, K Marek, L J Seidman, N Makris,[...]. Neurology 2003
H D Rosas, W J Koroshetz, Y I Chen, C Skeuse, M Vangel, M E Cudkowicz, K Caplan, K Marek, L J Seidman, N Makris,[...]. Neurology 2003
11
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
11
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice.
Xiaoping Tong, Yan Ao, Guido C Faas, Sinifunanya E Nwaobi, Ji Xu, Martin D Haustein, Mark A Anderson, Istvan Mody, Michelle L Olsen, Michael V Sofroniew,[...]. Nat Neurosci 2014
Xiaoping Tong, Yan Ao, Guido C Faas, Sinifunanya E Nwaobi, Ji Xu, Martin D Haustein, Mark A Anderson, Istvan Mody, Michelle L Olsen, Michael V Sofroniew,[...]. Nat Neurosci 2014
11
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice.
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
11
Corticostriatal synaptic adaptations in Huntington's disease.
Joshua L Plotkin, D James Surmeier. Curr Opin Neurobiol 2015
Joshua L Plotkin, D James Surmeier. Curr Opin Neurobiol 2015
15
Regional and cellular gene expression changes in human Huntington's disease brain.
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.