Selwyn S Jayakar, William P Dailey, Roderic G Eckenhoff, Jonathan B Cohen. J Biol Chem 2013
Times Cited: 63
Times Cited: 63
Times Cited
Times Co-cited
Similarity
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.
Hugues Nury, Catherine Van Renterghem, Yun Weng, Alphonso Tran, Marc Baaden, Virginie Dufresne, Jean-Pierre Changeux, James M Sonner, Marc Delarue, Pierre-Jean Corringer. Nature 2011
Hugues Nury, Catherine Van Renterghem, Yun Weng, Alphonso Tran, Marc Baaden, Virginie Dufresne, Jean-Pierre Changeux, James M Sonner, Marc Delarue, Pierre-Jean Corringer. Nature 2011
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Principles of activation and permeation in an anion-selective Cys-loop receptor.
Ryan E Hibbs, Eric Gouaux. Nature 2011
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A propofol binding site on mammalian GABAA receptors identified by photolabeling.
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Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Ludovic Sauguet, Rebecca J Howard, Laurie Malherbe, Ui S Lee, Pierre-Jean Corringer, R Adron Harris, Marc Delarue. Nat Commun 2013
Ludovic Sauguet, Rebecca J Howard, Laurie Malherbe, Ui S Lee, Pierre-Jean Corringer, R Adron Harris, Marc Delarue. Nat Commun 2013
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Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
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X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation.
Nicolas Bocquet, Hugues Nury, Marc Baaden, Chantal Le Poupon, Jean-Pierre Changeux, Marc Delarue, Pierre-Jean Corringer. Nature 2009
Nicolas Bocquet, Hugues Nury, Marc Baaden, Chantal Le Poupon, Jean-Pierre Changeux, Marc Delarue, Pierre-Jean Corringer. Nature 2009
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Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
Radovan Spurny, Bert Billen, Rebecca J Howard, Marijke Brams, Sarah Debaveye, Kerry L Price, David A Weston, Sergei V Strelkov, Jan Tytgat, Sonia Bertrand,[...]. J Biol Chem 2013
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Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector.
Selvanayagam Nirthanan, Galo Garcia, David C Chiara, S Shaukat Husain, Jonathan B Cohen. J Biol Chem 2008
Selvanayagam Nirthanan, Galo Garcia, David C Chiara, S Shaukat Husain, Jonathan B Cohen. J Biol Chem 2008
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Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog.
Selwyn S Jayakar, Xiaojuan Zhou, David C Chiara, Zuzana Dostalova, Pavel Y Savechenkov, Karol S Bruzik, William P Dailey, Keith W Miller, Roderic G Eckenhoff, Jonathan B Cohen. J Biol Chem 2014
Selwyn S Jayakar, Xiaojuan Zhou, David C Chiara, Zuzana Dostalova, Pavel Y Savechenkov, Karol S Bruzik, William P Dailey, Keith W Miller, Roderic G Eckenhoff, Jonathan B Cohen. J Biol Chem 2014
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Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane.
David C Chiara, Lawrence J Dangott, Roderic G Eckenhoff, Jonathan B Cohen. Biochemistry 2003
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Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel.
Ricarda J C Hilf, Raimund Dutzler. Nature 2009
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X-ray structure of a prokaryotic pentameric ligand-gated ion channel.
Ricarda J C Hilf, Raimund Dutzler. Nature 2008
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Multiple transmembrane binding sites for p-trifluoromethyldiazirinyl-etomidate, a photoreactive Torpedo nicotinic acetylcholine receptor allosteric inhibitor.
Ayman K Hamouda, Deirdre S Stewart, S Shaukat Husain, Jonathan B Cohen. J Biol Chem 2011
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Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue.
David C Chiara, Zuzana Dostalova, Selwyn S Jayakar, Xiaojuan Zhou, Keith W Miller, Jonathan B Cohen. Biochemistry 2012
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Photoaffinity labeling the propofol binding site in GLIC.
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X-ray structure of the mouse serotonin 5-HT3 receptor.
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Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel.
Yun Weng, Liya Yang, Pierre-Jean Corringer, James M Sonner. Anesth Analg 2010
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Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.
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Guo-Dong Li, David C Chiara, Gregory W Sawyer, S Shaukat Husain, Richard W Olsen, Jonathan B Cohen. J Neurosci 2006
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Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor.
David C Chiara, Selwyn S Jayakar, Xiaojuan Zhou, Xi Zhang, Pavel Y Savechenkov, Karol S Bruzik, Keith W Miller, Jonathan B Cohen. J Biol Chem 2013
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A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Marie S Prevost, Ludovic Sauguet, Hugues Nury, Catherine Van Renterghem, Christèle Huon, Frederic Poitevin, Marc Baaden, Marc Delarue, Pierre-Jean Corringer. Nat Struct Mol Biol 2012
Marie S Prevost, Ludovic Sauguet, Hugues Nury, Catherine Van Renterghem, Christèle Huon, Frederic Poitevin, Marc Baaden, Marc Delarue, Pierre-Jean Corringer. Nat Struct Mol Biol 2012
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General anesthetics predicted to block the GLIC pore with micromolar affinity.
David N LeBard, Jérôme Hénin, Roderic G Eckenhoff, Michael L Klein, Grace Brannigan. PLoS Comput Biol 2012
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Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels.
Stuart A Forman, Keith W Miller. Can J Anaesth 2011
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m-Azipropofol (AziPm) a photoactive analogue of the intravenous general anesthetic propofol.
Michael A Hall, Jin Xi, Chong Lor, Shuiping Dai, Robert Pearce, William P Dailey, Roderic G Eckenhoff. J Med Chem 2010
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Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavities.
Borna Ghosh, Kenneth A Satyshur, Cynthia Czajkowski. J Biol Chem 2013
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X-ray structure of the human α4β2 nicotinic receptor.
Claudio L Morales-Perez, Colleen M Noviello, Ryan E Hibbs. Nature 2016
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Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain.
Grace Brannigan, David N LeBard, Jérôme Hénin, Roderic G Eckenhoff, Michael L Klein. Proc Natl Acad Sci U S A 2010
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General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal.
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Identification of binding sites in the nicotinic acetylcholine receptor for [3H]azietomidate, a photoactivatable general anesthetic.
Michael R Ziebell, Selvanayagam Nirthanan, S Shaukat Husain, Keith W Miller, Jonathan B Cohen. J Biol Chem 2004
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Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study.
Enrique Arevalo, David C Chiara, Stuart A Forman, Jonathan B Cohen, Keith W Miller. J Biol Chem 2005
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Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine.
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Identification of sites of incorporation in the nicotinic acetylcholine receptor of a photoactivatible general anesthetic.
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Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.
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Glycine receptor mechanism elucidated by electron cryo-microscopy.
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Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.