A citation-based method for searching scientific literature

Shannon E Boye, Sanford L Boye, Alfred S Lewin, William W Hauswirth. Mol Ther 2013
Times Cited: 194







List of co-cited articles
1045 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Safety and efficacy of gene transfer for Leber's congenital amaurosis.
Albert M Maguire, Francesca Simonelli, Eric A Pierce, Edward N Pugh, Federico Mingozzi, Jeannette Bennicelli, Sandro Banfi, Kathleen A Marshall, Francesco Testa, Enrico M Surace,[...]. N Engl J Med 2008
27

Effect of gene therapy on visual function in Leber's congenital amaurosis.
James W B Bainbridge, Alexander J Smith, Susie S Barker, Scott Robbie, Robert Henderson, Kamaljit Balaggan, Ananth Viswanathan, Graham E Holder, Andrew Stockman, Nick Tyler,[...]. N Engl J Med 2008
22

Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial.
Robert E MacLaren, Markus Groppe, Alun R Barnard, Charles L Cottriall, Tanya Tolmachova, Len Seymour, K Reed Clark, Matthew J During, Frans P M Cremers, Graeme C M Black,[...]. Lancet 2014
522
17

Retinitis pigmentosa.
Dyonne T Hartong, Eliot L Berson, Thaddeus P Dryja. Lancet 2006
15

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial.
William W Hauswirth, Tomas S Aleman, Shalesh Kaushal, Artur V Cideciyan, Sharon B Schwartz, Lili Wang, Thomas J Conlon, Sanford L Boye, Terence R Flotte, Barry J Byrne,[...]. Hum Gene Ther 2008
726
15

Clinical applications of retinal gene therapy.
Daniel M Lipinski, Miriam Thake, Robert E MacLaren. Prog Retin Eye Res 2013
88
14

Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.
Samuel G Jacobson, Artur V Cideciyan, Ramakrishna Ratnakaram, Elise Heon, Sharon B Schwartz, Alejandro J Roman, Marc C Peden, Tomas S Aleman, Sanford L Boye, Alexander Sumaroka,[...]. Arch Ophthalmol 2012
440
13

Long-term effect of gene therapy on Leber's congenital amaurosis.
James W B Bainbridge, Manjit S Mehat, Venki Sundaram, Scott J Robbie, Susie E Barker, Caterina Ripamonti, Anastasios Georgiadis, Freya M Mowat, Stuart G Beattie, Peter J Gardner,[...]. N Engl J Med 2015
456
13

In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous.
Deniz Dalkara, Leah C Byrne, Ryan R Klimczak, Meike Visel, Lu Yin, William H Merigan, John G Flannery, David V Schaffer. Sci Transl Med 2013
401
12

In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa.
Benjamin Bakondi, Wenjian Lv, Bin Lu, Melissa K Jones, Yuchun Tsai, Kevin J Kim, Rachelle Levy, Aslam Abbasi Akhtar, Joshua J Breunig, Clive N Svendsen,[...]. Mol Ther 2016
189
11

Vector platforms for gene therapy of inherited retinopathies.
Ivana Trapani, Agostina Puppo, Alberto Auricchio. Prog Retin Eye Res 2014
88
12

Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial.
Stephen Russell, Jean Bennett, Jennifer A Wellman, Daniel C Chung, Zi-Fan Yu, Amy Tillman, Janet Wittes, Julie Pappas, Okan Elci, Sarah McCague,[...]. Lancet 2017
725
11

DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.
Zongchao Han, Shannon M Conley, Rasha S Makkia, Mark J Cooper, Muna I Naash. J Clin Invest 2012
101
10

Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapy.
J Kong, S-R Kim, K Binley, I Pata, K Doi, J Mannik, J Zernant-Rajang, O Kan, S Iqball, S Naylor,[...]. Gene Ther 2008
150
9

Retinal gene delivery by adeno-associated virus (AAV) vectors: Strategies and applications.
Christian Schön, Martin Biel, Stylianos Michalakis. Eur J Pharm Biopharm 2015
46
19

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial.
Albert M Maguire, Katherine A High, Alberto Auricchio, J Fraser Wright, Eric A Pierce, Francesco Testa, Federico Mingozzi, Jeannette L Bennicelli, Gui-shuang Ying, Settimio Rossi,[...]. Lancet 2009
592
9

Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement.
Artur V Cideciyan, Samuel G Jacobson, William A Beltran, Alexander Sumaroka, Malgorzata Swider, Simone Iwabe, Alejandro J Roman, Melani B Olivares, Sharon B Schwartz, András M Komáromy,[...]. Proc Natl Acad Sci U S A 2013
301
9

In vivo genome editing using Staphylococcus aureus Cas9.
F Ann Ran, Le Cong, Winston X Yan, David A Scott, Jonathan S Gootenberg, Andrea J Kriz, Bernd Zetsche, Ophir Shalem, Xuebing Wu, Kira S Makarova,[...]. Nature 2015
9

Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa.
Volker Busskamp, Jens Duebel, David Balya, Mathias Fradot, Tim James Viney, Sandra Siegert, Anna C Groner, Erik Cabuy, Valérie Forster, Mathias Seeliger,[...]. Science 2010
399
9

Leber congenital amaurosis: genes, proteins and disease mechanisms.
Anneke I den Hollander, Ronald Roepman, Robert K Koenekoop, Frans P M Cremers. Prog Retin Eye Res 2008
544
8

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.
Artur V Cideciyan, Tomas S Aleman, Sanford L Boye, Sharon B Schwartz, Shalesh Kaushal, Alejandro J Roman, Ji-Jing Pang, Alexander Sumaroka, Elizabeth A M Windsor, James M Wilson,[...]. Proc Natl Acad Sci U S A 2008
538
8

Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
8

Therapeutic genome editing: prospects and challenges.
David Benjamin Turitz Cox, Randall Jeffrey Platt, Feng Zhang. Nat Med 2015
684
8

Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies.
Steven D Schwartz, Carl D Regillo, Byron L Lam, Dean Eliott, Philip J Rosenfeld, Ninel Z Gregori, Jean-Pierre Hubschman, Janet L Davis, Gad Heilwell, Marc Spirn,[...]. Lancet 2015
720
8

Three-year follow-up after unilateral subretinal delivery of adeno-associated virus in patients with Leber congenital Amaurosis type 2.
Francesco Testa, Albert M Maguire, Settimio Rossi, Eric A Pierce, Paolo Melillo, Kathleen Marshall, Sandro Banfi, Enrico M Surace, Junwei Sun, Carmela Acerra,[...]. Ophthalmology 2013
225
8

Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial.
Jean Bennett, Jennifer Wellman, Kathleen A Marshall, Sarah McCague, Manzar Ashtari, Julie DiStefano-Pappas, Okan U Elci, Daniel C Chung, Junwei Sun, J Fraser Wright,[...]. Lancet 2016
261
8

Engineering adeno-associated viruses for clinical gene therapy.
Melissa A Kotterman, David V Schaffer. Nat Rev Genet 2014
460
8

Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.
Christine N Kay, Renee C Ryals, George V Aslanidi, Seok Hong Min, Qing Ruan, Jingfen Sun, Frank M Dyka, Daniel Kasuga, Andrea E Ayala, Kim Van Vliet,[...]. PLoS One 2013
122
7

Non-viral ocular gene therapy: potential ocular therapeutic avenues.
C Bloquel, J L Bourges, E Touchard, M Berdugo, D BenEzra, F Behar-Cohen. Adv Drug Deliv Rev 2006
60
11

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
7

Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year.
Artur V Cideciyan, William W Hauswirth, Tomas S Aleman, Shalesh Kaushal, Sharon B Schwartz, Sanford L Boye, Elizabeth A M Windsor, Thomas J Conlon, Alexander Sumaroka, Ji-Jing Pang,[...]. Hum Gene Ther 2009
247
7

Genes and mutations causing retinitis pigmentosa.
S P Daiger, L S Sullivan, S J Bowne. Clin Genet 2013
339
7

Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial.
Elizabeth P Rakoczy, Chooi-May Lai, Aaron L Magno, Matthew E Wikstrom, Martyn A French, Cora M Pierce, Steven D Schwartz, Mark S Blumenkranz, Thomas W Chalberg, Mariapia A Degli-Esposti,[...]. Lancet 2015
113
7

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors.
Hilda Petrs-Silva, Astra Dinculescu, Qiuhong Li, Seok-Hong Min, Vince Chiodo, Ji-Jing Pang, Li Zhong, Sergei Zolotukhin, Arun Srivastava, Alfred S Lewin,[...]. Mol Ther 2009
289
7

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.
Hilda Petrs-Silva, Astra Dinculescu, Qiuhong Li, Wen-Tao Deng, Ji-Jing Pang, Seok-Hong Min, Vince Chiodo, Andy W Neeley, Lakshmanan Govindasamy, Antonette Bennett,[...]. Mol Ther 2011
183
7

Improvement and decline in vision with gene therapy in childhood blindness.
Samuel G Jacobson, Artur V Cideciyan, Alejandro J Roman, Alexander Sumaroka, Sharon B Schwartz, Elise Heon, William W Hauswirth. N Engl J Med 2015
243
7

A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells.
Ryan R Klimczak, James T Koerber, Deniz Dalkara, John G Flannery, David V Schaffer. PLoS One 2009
129
7

Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
6

Effective delivery of large genes to the retina by dual AAV vectors.
Ivana Trapani, Pasqualina Colella, Andrea Sommella, Carolina Iodice, Giulia Cesi, Sonia de Simone, Elena Marrocco, Settimio Rossi, Massimo Giunti, Arpad Palfi,[...]. EMBO Mol Med 2014
141
6

Effect of genome size on AAV vector packaging.
Zhijian Wu, Hongyan Yang, Peter Colosi. Mol Ther 2010
463
6

Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65.
A Georgiadis, Y Duran, J Ribeiro, L Abelleira-Hervas, S J Robbie, B Sünkel-Laing, S Fourali, A Gonzalez-Cordero, E Cristante, M Michaelides,[...]. Gene Ther 2016
48
12

Preclinical safety evaluation of AAV2-sFLT01- a gene therapy for age-related macular degeneration.
Timothy K Maclachlan, Michael Lukason, Margaret Collins, Robert Munger, Elisabete Isenberger, Cindy Rogers, Shana Malatos, Elizabeth Dufresne, James Morris, Roberto Calcedo,[...]. Mol Ther 2011
115
6

Transduction of photoreceptors with equine infectious anemia virus lentiviral vectors: safety and biodistribution of StarGen for Stargardt disease.
Katie Binley, Peter Widdowson, Julie Loader, Michelle Kelleher, Sharifah Iqball, Georgina Ferrige, Jackie de Belin, Marie Carlucci, Diana Angell-Manning, Felicity Hurst,[...]. Invest Ophthalmol Vis Sci 2013
79
7

Long-term safety and efficacy of factor IX gene therapy in hemophilia B.
Amit C Nathwani, Ulreke M Reiss, Edward G D Tuddenham, Cecilia Rosales, Pratima Chowdary, Jenny McIntosh, Marco Della Peruta, Elsa Lheriteau, Nishal Patel, Deepak Raj,[...]. N Engl J Med 2014
762
6

Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey.
Luk H Vandenberghe, Peter Bell, Albert M Maguire, Cassia N Cearley, Ru Xiao, Roberto Calcedo, Lili Wang, Michael J Castle, Alexandra C Maguire, Rebecca Grant,[...]. Sci Transl Med 2011
142
6

DNA targeting specificity of RNA-guided Cas9 nucleases.
Patrick D Hsu, David A Scott, Joshua A Weinstein, F Ann Ran, Silvana Konermann, Vineeta Agarwala, Yinqing Li, Eli J Fine, Xuebing Wu, Ophir Shalem,[...]. Nat Biotechnol 2013
6

AAV2 gene therapy readministration in three adults with congenital blindness.
Jean Bennett, Manzar Ashtari, Jennifer Wellman, Kathleen A Marshall, Laura L Cyckowski, Daniel C Chung, Sarah McCague, Eric A Pierce, Yifeng Chen, Jeannette L Bennicelli,[...]. Sci Transl Med 2012
282
6

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni.
Eunji Kim, Taeyoung Koo, Sung Wook Park, Daesik Kim, Kyoungmi Kim, Hee-Yeon Cho, Dong Woo Song, Kyu Jun Lee, Min Hee Jung, Seokjoong Kim,[...]. Nat Commun 2017
333
6

Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice.
Wenhan Yu, Suddhasil Mookherjee, Vijender Chaitankar, Suja Hiriyanna, Jung-Woong Kim, Matthew Brooks, Yasaman Ataeijannati, Xun Sun, Lijin Dong, Tiansen Li,[...]. Nat Commun 2017
164
6

Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.
Deniz Dalkara, Kathleen D Kolstad, Natalia Caporale, Meike Visel, Ryan R Klimczak, David V Schaffer, John G Flannery. Mol Ther 2009
192
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.