A citation-based method for searching scientific literature

Aniruddha J Deshpande, Liying Chen, Maurizio Fazio, Amit U Sinha, Kathrin M Bernt, Deepti Banka, Stuart Dias, Jenny Chang, Edward J Olhava, Scott R Daigle, Victoria M Richon, Roy M Pollock, Scott A Armstrong. Blood 2013
Times Cited: 118







List of co-cited articles
1644 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Aravind Basavapathruni, Lei Jin, P Ann Boriack-Sjodin, Christina J Allain, Christine R Klaus, Alejandra Raimondi, Margaret Porter Scott,[...]. Blood 2013
464
68

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Christina R Majer, Christopher J Sneeringer, Jeffrey Song, L Danielle Johnston, Margaret Porter Scott, Jesse J Smith, Yonghong Xiao,[...]. Cancer Cell 2011
644
64

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Kathrin M Bernt, Nan Zhu, Amit U Sinha, Sridhar Vempati, Joerg Faber, Andrei V Krivtsov, Zhaohui Feng, Natalie Punt, Amanda Daigle, Lars Bullinger,[...]. Cancer Cell 2011
596
64

hDOT1L links histone methylation to leukemogenesis.
Yuki Okada, Qin Feng, Yihui Lin, Qi Jiang, Yaqiang Li, Vernon M Coffield, Lishan Su, Guoliang Xu, Yi Zhang. Cell 2005
592
45

Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.
L Chen, A J Deshpande, D Banka, K M Bernt, S Dias, C Buske, E J Olhava, S R Daigle, V M Richon, R M Pollock,[...]. Leukemia 2013
100
41

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Anh Tram Nguyen, Olena Taranova, Jin He, Yi Zhang. Blood 2011
179
40

H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Andrei V Krivtsov, Zhaohui Feng, Madeleine E Lemieux, Joerg Faber, Sridhar Vempati, Amit U Sinha, Xiaobo Xia, Jonathan Jesneck, Adrian P Bracken, Lewis B Silverman,[...]. Cancer Cell 2008
392
31

A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification.
Dorothee Mueller, Christian Bach, Deniz Zeisig, Maria-Paz Garcia-Cuellar, Sara Monroe, Arun Sreekumar, Rong Zhou, Alexey Nesvizhskii, Arul Chinnaiyan, Jay L Hess,[...]. Blood 2007
281
30

MLL translocations, histone modifications and leukaemia stem-cell development.
Andrei V Krivtsov, Scott A Armstrong. Nat Rev Cancer 2007
797
29

Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
Ming-Jin Chang, Hongyu Wu, Nicholas J Achille, Mary Rose Reisenauer, Chau-Wen Chou, Nancy J Zeleznik-Le, Charles S Hemenway, Wenzheng Zhang. Cancer Res 2010
123
27

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Wenyu Yu, Emma J Chory, Amy K Wernimont, Wolfram Tempel, Alex Scopton, Alexander Federation, Jason J Marineau, Jun Qi, Dalia Barsyte-Lovejoy, Joanna Yi,[...]. Nat Commun 2012
188
27

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Qin Feng, Hengbin Wang, Huck Hui Ng, Hediye Erdjument-Bromage, Paul Tempst, Kevin Struhl, Yi Zhang. Curr Biol 2002
571
25

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Aniruddha J Deshpande, Anagha Deshpande, Amit U Sinha, Liying Chen, Jenny Chang, Ali Cihan, Maurizio Fazio, Chun-Wei Chen, Nan Zhu, Richard Koche,[...]. Cancer Cell 2014
108
25

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Stephanie Y Jo, Eric M Granowicz, Ivan Maillard, Dafydd Thomas, Jay L Hess. Blood 2011
148
24

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Johannes Zuber, Junwei Shi, Eric Wang, Amy R Rappaport, Harald Herrmann, Edward A Sison, Daniel Magoon, Jun Qi, Katharina Blatt, Mark Wunderlich,[...]. Nature 2011
24

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Andrei V Krivtsov, David Twomey, Zhaohui Feng, Matthew C Stubbs, Yingzi Wang, Joerg Faber, Jason E Levine, Jing Wang, William C Hahn, D Gary Gilliland,[...]. Nature 2006
24

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Chun-Wei Chen, Richard P Koche, Amit U Sinha, Aniruddha J Deshpande, Nan Zhu, Rowena Eng, John G Doench, Haiming Xu, Scott H Chu, Jun Qi,[...]. Nat Med 2015
142
24

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Akihiko Yokoyama, Tim C P Somervaille, Kevin S Smith, Orit Rozenblatt-Rosen, Matthew Meyerson, Michael L Cleary. Cell 2005
378
23

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.
Akihiko Yokoyama, Min Lin, Alpana Naresh, Issay Kitabayashi, Michael L Cleary. Cancer Cell 2010
252
23

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Mark A Dawson, Rab K Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C Robson, Chun-wa Chung, Carsten Hopf, Mikhail M Savitski,[...]. Nature 2011
21

MLL targets SET domain methyltransferase activity to Hox gene promoters.
Thomas A Milne, Scott D Briggs, Hugh W Brock, Mary Ellen Martin, Denise Gibbs, C David Allis, Jay L Hess. Mol Cell 2002
788
21

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.
Michael T McCabe, Heidi M Ott, Gopinath Ganji, Susan Korenchuk, Christine Thompson, Glenn S Van Aller, Yan Liu, Alan P Graves, Anthony Della Pietra, Elsie Diaz,[...]. Nature 2012
20

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).
Man Mohan, Hans-Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P Washburn, Laurence Florens, Ali Shilatifard. Genes Dev 2010
210
20

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.
Dmitry Borkin, Shihan He, Hongzhi Miao, Katarzyna Kempinska, Jonathan Pollock, Jennifer Chase, Trupta Purohit, Bhavna Malik, Ting Zhao, Jingya Wang,[...]. Cancer Cell 2015
207
20


DOT1L inhibitor EPZ-5676 displays synergistic antiproliferative activity in combination with standard of care drugs and hypomethylating agents in MLL-rearranged leukemia cells.
Christine R Klaus, Dorothy Iwanowicz, Danielle Johnston, Carly A Campbell, Jesse J Smith, Mikel P Moyer, Robert A Copeland, Edward J Olhava, Margaret Porter Scott, Roy M Pollock,[...]. J Pharmacol Exp Ther 2014
76
25

The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.
Eytan M Stein, Guillermo Garcia-Manero, David A Rizzieri, Raoul Tibes, Jesus G Berdeja, Michael R Savona, Mojca Jongen-Lavrenic, Jessica K Altman, Blythe Thomson, Stephen J Blakemore,[...]. Blood 2018
191
19

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.
Ryan D Morin, Nathalie A Johnson, Tesa M Severson, Andrew J Mungall, Jianghong An, Rodrigo Goya, Jessica E Paul, Merrill Boyle, Bruce W Woolcock, Florian Kuchenbauer,[...]. Nat Genet 2010
18

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
Sarah K Knutson, Tim J Wigle, Natalie M Warholic, Christopher J Sneeringer, Christina J Allain, Christine R Klaus, Joelle D Sacks, Alejandra Raimondi, Christina R Majer, Jeffrey Song,[...]. Nat Chem Biol 2012
556
17

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
David J Steger, Martina I Lefterova, Lei Ying, Aaron J Stonestrom, Michael Schupp, David Zhuo, Adam L Vakoc, Ja-Eun Kim, Junjie Chen, Mitchell A Lazar,[...]. Mol Cell Biol 2008
323
17

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
Yujiang Shi, Fei Lan, Caitlin Matson, Peter Mulligan, Johnathan R Whetstine, Philip A Cole, Robert A Casero, Yang Shi. Cell 2004
16

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
Matthew G Guenther, Lee N Lawton, Tatiana Rozovskaia, Garrett M Frampton, Stuart S Levine, Thomas L Volkert, Carlo M Croce, Tatsuya Nakamura, Eli Canaani, Richard A Young. Genes Dev 2008
201
16


The pathogenesis of mixed-lineage leukemia.
Andrew G Muntean, Jay L Hess. Annu Rev Pathol 2012
224
16

MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition.
Michael W M Kühn, Michael J Hadler, Scott R Daigle, Richard P Koche, Andrei V Krivtsov, Edward J Olhava, Michael A Caligiuri, Gang Huang, James E Bradner, Roy M Pollock,[...]. Haematologica 2015
37
43

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders.
Thomas Ernst, Andrew J Chase, Joannah Score, Claire E Hidalgo-Curtis, Catherine Bryant, Amy V Jones, Katherine Waghorn, Katerina Zoi, Fiona M Ross, Andreas Reiter,[...]. Nat Genet 2010
836
15

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.
Jolanta Grembecka, Shihan He, Aibin Shi, Trupta Purohit, Andrew G Muntean, Roderick J Sorenson, Hollis D Showalter, Marcelo J Murai, Amalia M Belcher, Thomas Hartley,[...]. Nat Chem Biol 2012
255
15

DNMT3A mutations in acute myeloid leukemia.
Timothy J Ley, Li Ding, Matthew J Walter, Michael D McLellan, Tamara Lamprecht, David E Larson, Cyriac Kandoth, Jacqueline E Payton, Jack Baty, John Welch,[...]. N Engl J Med 2010
15

The diverse functions of Dot1 and H3K79 methylation.
Anh Tram Nguyen, Yi Zhang. Genes Dev 2011
366
15

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Debabrata Biswas, Thomas A Milne, Venkatesha Basrur, Jaehoon Kim, Kojo S J Elenitoba-Johnson, C David Allis, Robert G Roeder. Proc Natl Acad Sci U S A 2011
125
15

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
Timothy J Ley, Christopher Miller, Li Ding, Benjamin J Raphael, Andrew J Mungall, A Gordon Robertson, Katherine Hoadley, Timothy J Triche, Peter W Laird, Jack D Baty,[...]. N Engl J Med 2013
15

The MLL recombinome of acute leukemias in 2013.
C Meyer, J Hofmann, T Burmeister, D Gröger, T S Park, M Emerenciano, M Pombo de Oliveira, A Renneville, P Villarese, E Macintyre,[...]. Leukemia 2013
307
15


The MLL recombinome of acute leukemias in 2017.
C Meyer, T Burmeister, D Gröger, G Tsaur, L Fechina, A Renneville, R Sutton, N C Venn, M Emerenciano, M S Pombo-de-Oliveira,[...]. Leukemia 2018
311
15

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.
Liran I Shlush, Sasan Zandi, Amanda Mitchell, Weihsu Claire Chen, Joseph M Brandwein, Vikas Gupta, James A Kennedy, Aaron D Schimmer, Andre C Schuh, Karen W Yee,[...]. Nature 2014
947
14

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Tino Schenk, Weihsu Claire Chen, Stefanie Göllner, Louise Howell, Liqing Jin, Katja Hebestreit, Hans-Ulrich Klein, Andreea C Popescu, Alan Burnett, Ken Mills,[...]. Nat Med 2012
462
14

Altered Hox expression and segmental identity in Mll-mutant mice.
B D Yu, J L Hess, S E Horning, G A Brown, S J Korsmeyer. Nature 1995
685
14

The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.
William J Harris, Xu Huang, James T Lynch, Gary J Spencer, James R Hitchin, Yaoyong Li, Filippo Ciceri, Julian G Blaser, Brigit F Greystoke, Allan M Jordan,[...]. Cancer Cell 2012
395
14

Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Tobias Neff, Amit U Sinha, Michael J Kluk, Nan Zhu, Mohamed H Khattab, Lauren Stein, Huafeng Xie, Stuart H Orkin, Scott A Armstrong. Proc Natl Acad Sci U S A 2012
160
14

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
Jay P Patel, Mithat Gönen, Maria E Figueroa, Hugo Fernandez, Zhuoxin Sun, Janis Racevskis, Pieter Van Vlierberghe, Igor Dolgalev, Sabrena Thomas, Olga Aminova,[...]. N Engl J Med 2012
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.