Hemali P Phatnani, Paolo Guarnieri, Brad A Friedman, Monica A Carrasco, Michael Muratet, Sean O'Keeffe, Chiamaka Nwakeze, Florencia Pauli-Behn, Kimberly M Newberry, Sarah K Meadows, Juan Carlos Tapia, Richard M Myers, Tom Maniatis. Proc Natl Acad Sci U S A 2013
Times Cited: 90
Times Cited: 90
Times Cited
Times Co-cited
Similarity
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust,[...]. Nat Biotechnol 2011
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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
M E Gurney, H Pu, A Y Chiu, M C Dal Canto, C Y Polchow, D D Alexander, J Caliendo, A Hentati, Y W Kwon, H X Deng. Science 1994
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
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Onset and progression in inherited ALS determined by motor neurons and microglia.
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
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Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
A M Clement, M D Nguyen, E A Roberts, M L Garcia, S Boillée, M Rule, A P McMahon, W Doucette, D Siwek, R J Ferrante,[...]. Science 2003
A M Clement, M D Nguyen, E A Roberts, M L Garcia, S Boillée, M Rule, A P McMahon, W Doucette, D Siwek, R J Ferrante,[...]. Science 2003
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Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis.
Laura Ferraiuolo, Adrian Higginbottom, Paul R Heath, Sian Barber, David Greenald, Janine Kirby, Pamela J Shaw. Brain 2011
Laura Ferraiuolo, Adrian Higginbottom, Paul R Heath, Sian Barber, David Greenald, Janine Kirby, Pamela J Shaw. Brain 2011
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Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells.
Maria C N Marchetto, Alysson R Muotri, Yangling Mu, Alan M Smith, Gabriela G Cezar, Fred H Gage. Cell Stem Cell 2008
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Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
Sophia T Papadeas, Sarah E Kraig, Colin O'Banion, Angelo C Lepore, Nicholas J Maragakis. Proc Natl Acad Sci U S A 2011
Sophia T Papadeas, Sarah E Kraig, Colin O'Banion, Angelo C Lepore, Nicholas J Maragakis. Proc Natl Acad Sci U S A 2011
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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.
Hristelina Ilieva, Magdalini Polymenidou, Don W Cleveland. J Cell Biol 2009
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Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Andrea Serio, Bilada Bilican, Sami J Barmada, Dale Michael Ando, Chen Zhao, Rick Siller, Karen Burr, Ghazal Haghi, David Story, Agnes Lumi Nishimura,[...]. Proc Natl Acad Sci U S A 2013
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Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.
Lijun Wang, David H Gutmann, Raymond P Roos. Hum Mol Genet 2011
Lijun Wang, David H Gutmann, Raymond P Roos. Hum Mol Genet 2011
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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
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Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
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Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
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Neurotoxic reactive astrocytes are induced by activated microglia.
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Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
20
Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats.
Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou, Xu-Gang Xia. EMBO J 2013
Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou, Xu-Gang Xia. EMBO J 2013
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ALS: a disease of motor neurons and their nonneuronal neighbors.
Séverine Boillée, Christine Vande Velde, Don W Cleveland. Neuron 2006
Séverine Boillée, Christine Vande Velde, Don W Cleveland. Neuron 2006
18
Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
Ashley E Frakes, Laura Ferraiuolo, Amanda M Haidet-Phillips, Leah Schmelzer, Lyndsey Braun, Carlos J Miranda, Katherine J Ladner, Adam K Bevan, Kevin D Foust, Jonathan P Godbout,[...]. Neuron 2014
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18
Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells.
Fumito Endo, Okiru Komine, Noriko Fujimori-Tonou, Masahisa Katsuno, Shijie Jin, Seiji Watanabe, Gen Sobue, Mari Dezawa, Tony Wyss-Coray, Koji Yamanaka. Cell Rep 2015
Fumito Endo, Okiru Komine, Noriko Fujimori-Tonou, Masahisa Katsuno, Shijie Jin, Seiji Watanabe, Gen Sobue, Mari Dezawa, Tony Wyss-Coray, Koji Yamanaka. Cell Rep 2015
18
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
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17
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
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17
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.
Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragakis. Nat Neurosci 2008
Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragakis. Nat Neurosci 2008
16
Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis.
Pablo Díaz-Amarilla, Silvia Olivera-Bravo, Emiliano Trias, Andrea Cragnolini, Laura Martínez-Palma, Patricia Cassina, Joseph Beckman, Luis Barbeito. Proc Natl Acad Sci U S A 2011
Pablo Díaz-Amarilla, Silvia Olivera-Bravo, Emiliano Trias, Andrea Cragnolini, Laura Martínez-Palma, Patricia Cassina, Joseph Beckman, Luis Barbeito. Proc Natl Acad Sci U S A 2011
16
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).
David S Howland, Jian Liu, Yijin She, Beth Goad, Nicholas J Maragakis, Benjamin Kim, Jamie Erickson, John Kulik, Lisa DeVito, George Psaltis,[...]. Proc Natl Acad Sci U S A 2002
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15
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
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Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis.
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Genomic analysis of reactive astrogliosis.
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
14
A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.
Isaac M Chiu, Emiko T A Morimoto, Hani Goodarzi, Jennifer T Liao, Sean O'Keeffe, Hemali P Phatnani, Michael Muratet, Michael C Carroll, Shawn Levy, Saeed Tavazoie,[...]. Cell Rep 2013
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14
State of play in amyotrophic lateral sclerosis genetics.
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014
14
Necroptosis drives motor neuron death in models of both sporadic and familial ALS.
Diane B Re, Virginia Le Verche, Changhao Yu, Mackenzie W Amoroso, Kristin A Politi, Sudarshan Phani, Burcin Ikiz, Lucas Hoffmann, Martijn Koolen, Tetsuya Nagata,[...]. Neuron 2014
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14
Mutations of optineurin in amyotrophic lateral sclerosis.
Hirofumi Maruyama, Hiroyuki Morino, Hidefumi Ito, Yuishin Izumi, Hidemasa Kato, Yasuhito Watanabe, Yoshimi Kinoshita, Masaki Kamada, Hiroyuki Nodera, Hidenori Suzuki,[...]. Nature 2010
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13
Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
Patricia Cassina, Adriana Cassina, Mariana Pehar, Raquel Castellanos, Mandi Gandelman, Andrés de León, Kristine M Robinson, Ronald P Mason, Joseph S Beckman, Luis Barbeito,[...]. J Neurosci 2008
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Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease.
Thomas Philips, Wim Robberecht. Lancet Neurol 2011
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13
Altered astrocytic expression of TDP-43 does not influence motor neuron survival.
Amanda M Haidet-Phillips, Sarah K Gross, Timothy Williams, Alisha Tuteja, Alex Sherman, Myungsung Ko, Yun H Jeong, Philip C Wong, Nicholas J Maragakis. Exp Neurol 2013
Amanda M Haidet-Phillips, Sarah K Gross, Timothy Williams, Alisha Tuteja, Alex Sherman, Myungsung Ko, Yun H Jeong, Philip C Wong, Nicholas J Maragakis. Exp Neurol 2013
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Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis.
Marcelo R Vargas, Delinda A Johnson, Daniel W Sirkis, Albee Messing, Jeffrey A Johnson. J Neurosci 2008
Marcelo R Vargas, Delinda A Johnson, Daniel W Sirkis, Albee Messing, Jeffrey A Johnson. J Neurosci 2008
12
IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1.
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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
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12
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.
Koji Yamanaka, Severine Boillee, Elizabeth A Roberts, Michael L Garcia, Melissa McAlonis-Downes, Oliver R Mikse, Don W Cleveland, Lawrence S B Goldstein. Proc Natl Acad Sci U S A 2008
Koji Yamanaka, Severine Boillee, Elizabeth A Roberts, Michael L Garcia, Melissa McAlonis-Downes, Oliver R Mikse, Don W Cleveland, Lawrence S B Goldstein. Proc Natl Acad Sci U S A 2008
12
Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS.
Bing Liao, Weihua Zhao, David R Beers, Jenny S Henkel, Stanley H Appel. Exp Neurol 2012
Bing Liao, Weihua Zhao, David R Beers, Jenny S Henkel, Stanley H Appel. Exp Neurol 2012
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Heterogeneity of astrocytic form and function.
Nancy Ann Oberheim, Steven A Goldman, Maiken Nedergaard. Methods Mol Biol 2012
Nancy Ann Oberheim, Steven A Goldman, Maiken Nedergaard. Methods Mol Biol 2012
11
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
David R Beers, Jenny S Henkel, Qin Xiao, Weihua Zhao, Jinghong Wang, Albert A Yen, Laszlo Siklos, Scott R McKercher, Stanley H Appel. Proc Natl Acad Sci U S A 2006
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11
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS.
David R Beers, Jenny S Henkel, Weihua Zhao, Jinghong Wang, Stanley H Appel. Proc Natl Acad Sci U S A 2008
David R Beers, Jenny S Henkel, Weihua Zhao, Jinghong Wang, Stanley H Appel. Proc Natl Acad Sci U S A 2008
11
Oligodendroglia metabolically support axons and contribute to neurodegeneration.
Youngjin Lee, Brett M Morrison, Yun Li, Sylvain Lengacher, Mohamed H Farah, Paul N Hoffman, Yiting Liu, Akivaga Tsingalia, Lin Jin, Ping-Wu Zhang,[...]. Nature 2012
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11
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis.
Shin H Kang, Ying Li, Masahiro Fukaya, Ileana Lorenzini, Don W Cleveland, Lyle W Ostrow, Jeffrey D Rothstein, Dwight E Bergles. Nat Neurosci 2013
Shin H Kang, Ying Li, Masahiro Fukaya, Ileana Lorenzini, Don W Cleveland, Lyle W Ostrow, Jeffrey D Rothstein, Dwight E Bergles. Nat Neurosci 2013
11
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis.
Chi-Hong Wu, Claudia Fallini, Nicola Ticozzi, Pamela J Keagle, Peter C Sapp, Katarzyna Piotrowska, Patrick Lowe, Max Koppers, Diane McKenna-Yasek, Desiree M Baron,[...]. Nature 2012
Chi-Hong Wu, Claudia Fallini, Nicola Ticozzi, Pamela J Keagle, Peter C Sapp, Katarzyna Piotrowska, Patrick Lowe, Max Koppers, Diane McKenna-Yasek, Desiree M Baron,[...]. Nature 2012
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.