A citation-based method for searching scientific literature

Jianxiong Jiang, Yi Quan, Thota Ganesh, Wendy A Pouliot, F Edward Dudek, Raymond Dingledine. Proc Natl Acad Sci U S A 2013
Times Cited: 117







List of co-cited articles
1058 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2.
Jianxiong Jiang, Thota Ganesh, Yuhong Du, Yi Quan, Geidy Serrano, Min Qui, Iris Speigel, Asheebo Rojas, Nadia Lelutiu, Raymond Dingledine. Proc Natl Acad Sci U S A 2012
82
47

Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus.
Jianxiong Jiang, Myung-Soon Yang, Yi Quan, Paoula Gueorguieva, Thota Ganesh, Raymond Dingledine. Neurobiol Dis 2015
60
61

Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus.
G E Serrano, N Lelutiu, A Rojas, S Cochi, R Shaw, C D Makinson, D Wang, G A FitzGerald, R Dingledine. J Neurosci 2011
111
35

Cyclooxygenase-2 in epilepsy.
Asheebo Rojas, Jianxiong Jiang, Thota Ganesh, Myung-Soon Yang, Nadia Lelutiu, Paoula Gueorguieva, Raymond Dingledine. Epilepsia 2014
111
35

EP2 receptor signaling pathways regulate classical activation of microglia.
Yi Quan, Jianxiong Jiang, Ray Dingledine. J Biol Chem 2013
79
40


The role of inflammation in epilepsy.
Annamaria Vezzani, Jacqueline French, Tamas Bartfai, Tallie Z Baram. Nat Rev Neurol 2011
27


Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.
Jenny U Johansson, Suraj Pradhan, Ludmila A Lokteva, Nathaniel S Woodling, Novie Ko, Holden D Brown, Qian Wang, Christina Loh, Egle Cekanaviciute, Marion Buckwalter,[...]. J Neurosci 2013
63
38

Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus-induced deficits in the novel object recognition task in rats.
Asheebo Rojas, Thota Ganesh, Zahra Manji, Theon O'neill, Raymond Dingledine. Neuropharmacology 2016
51
47

Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.
Jianxiong Jiang, Thota Ganesh, Yuhong Du, Pahk Thepchatri, Asheebo Rojas, Iestyn Lewis, Serdar Kurtkaya, Lian Li, Min Qui, Geidy Serrano,[...]. Proc Natl Acad Sci U S A 2010
62
35

Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus.
Keun-Hwa Jung, Kon Chu, Soon-Tae Lee, Juhyun Kim, Dong-In Sinn, Jeong-Min Kim, Dong-Kyu Park, Jung-Ju Lee, Seung U Kim, Manho Kim,[...]. Neurobiol Dis 2006
220
22


Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.
Louise McCullough, Liejun Wu, Norman Haughey, Xibin Liang, Tracey Hand, Qian Wang, Richard M Breyer, Katrin Andreasson. J Neurosci 2004
296
21


Emerging roles of PGE2 receptors in models of neurological disease.
Katrin Andreasson. Prostaglandins Other Lipid Mediat 2010
138
20

Lead optimization studies of cinnamic amide EP2 antagonists.
Thota Ganesh, Jianxiong Jiang, Myung-Soon Yang, Ray Dingledine. J Med Chem 2014
34
55

Development of second generation EP2 antagonists with high selectivity.
Thota Ganesh, Jianxiong Jiang, Ray Dingledine. Eur J Med Chem 2014
26
73

Candidate drug targets for prevention or modification of epilepsy.
Nicholas H Varvel, Jianxiong Jiang, Raymond Dingledine. Annu Rev Pharmacol Toxicol 2015
48
37

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures.
Mattia Maroso, Silvia Balosso, Teresa Ravizza, Jaron Liu, Eleonora Aronica, Anand M Iyer, Carlo Rossetti, Monica Molteni, Maura Casalgrandi, Angelo A Manfredi,[...]. Nat Med 2010
587
17

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.
Xibin Liang, Qian Wang, Tracey Hand, Liejun Wu, Richard M Breyer, Thomas J Montine, Katrin Andreasson. J Neurosci 2005
188
17

The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis.
Xibin Liang, Qian Wang, Ju Shi, Ludmila Lokteva, Richard M Breyer, Thomas J Montine, Katrin Andreasson. Ann Neurol 2008
98
17

Effects of SC58236, a selective COX-2 inhibitor, on epileptogenesis and spontaneous seizures in a rat model for temporal lobe epilepsy.
L Holtman, E A van Vliet, R van Schaik, C M Queiroz, E Aronica, J A Gorter. Epilepsy Res 2009
81
20

Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists.
Thota Ganesh, Jianxiong Jiang, Rangaiah Shashidharamurthy, Ray Dingledine. ACS Med Chem Lett 2013
21
76

The role of inflammation in epileptogenesis.
Annamaria Vezzani, Alon Friedman, Raymond J Dingledine. Neuropharmacology 2013
296
16

Interleukin-1β biosynthesis inhibition reduces acute seizures and drug resistant chronic epileptic activity in mice.
Mattia Maroso, Silvia Balosso, Teresa Ravizza, Valentina Iori, Christopher Ian Wright, Jacqueline French, Annamaria Vezzani. Neurotherapeutics 2011
203
16

EP2 Receptor Signaling Regulates Microglia Death.
Yujiao Fu, Myung-Soon Yang, Jianxiong Jiang, Thota Ganesh, Eunhye Joe, Raymond Dingledine. Mol Pharmacol 2015
30
53

Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.
Jenny U Johansson, Nathaniel S Woodling, Qian Wang, Maharshi Panchal, Xibin Liang, Angel Trueba-Saiz, Holden D Brown, Siddhita D Mhatre, Taylor Loui, Katrin I Andreasson. J Clin Invest 2015
99
15

Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside.
Avijit Dey, Xu Kang, Jiange Qiu, Yifeng Du, Jianxiong Jiang. Trends Pharmacol Sci 2016
104
15

Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury.
Jianxiong Jiang, Ying Yu, Erika Reime Kinjo, Yifeng Du, Hoang Phuong Nguyen, Ray Dingledine. Neuropharmacology 2019
28
53

Interleukin-1beta contributes to the generation of experimental febrile seizures.
Celine Dubé, Annamaria Vezzani, Marga Behrens, Tamas Bartfai, Tallie Z Baram. Ann Neurol 2005
306
14

Cox-2 inhibition can lead to adverse effects in a rat model for temporal lobe epilepsy.
Linda Holtman, Erwin A van Vliet, Peter M Edelbroek, Eleonora Aronica, Jan A Gorter. Epilepsy Res 2010
62
22


Inflammation in epilepsy: clinical observations.
Eleonora Aronica, Peter B Crino. Epilepsia 2011
200
13

Neuroinflammatory targets and treatments for epilepsy validated in experimental models.
Eleonora Aronica, Sebastian Bauer, Yuri Bozzi, Matteo Caleo, Raymond Dingledine, Jan A Gorter, David C Henshall, Daniela Kaufer, Sookyong Koh, Wolfgang Löscher,[...]. Epilepsia 2017
90
14

Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype.
Xu Kang, Jiange Qiu, Qianqian Li, Katherine A Bell, Yifeng Du, Da Woon Jung, Jae Yeol Lee, Jiukuan Hao, Jianxiong Jiang. Sci Rep 2017
30
43

Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus.
M G De Simoni, C Perego, T Ravizza, D Moneta, M Conti, F Marchesi, A De Luigi, S Garattini, A Vezzani. Eur J Neurosci 2000
372
12

Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein.
Jinghua Jin, Feng-Shiun Shie, Jun Liu, Yan Wang, Jeanne Davis, Aimee M Schantz, Kathleen S Montine, Thomas J Montine, Jing Zhang. J Neuroinflammation 2007
89
13

Cyclooxygenase-2/PGE2 pathway facilitates pentylenetetrazol-induced seizures.
Mauro Schneider Oliveira, Ana Flávia Furian, Luiz Fernando Freire Royes, Michele Rechia Fighera, Natália Gindri Fiorenza, Marcelo Castelli, Pablo Machado, Denise Bohrer, Marlei Veiga, Juliano Ferreira,[...]. Epilepsy Res 2008
70
17


Prostaglandin E2 produced by late induced COX-2 stimulates hippocampal neuron loss after seizure in the CA3 region.
Takako Takemiya, Michiyo Maehara, Kiyoshi Matsumura, Shin Yasuda, Hiroko Sugiura, Kanato Yamagata. Neurosci Res 2006
86
13

COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats.
Erwin A van Vliet, Guido Zibell, Anton Pekcec, Juli Schlichtiger, Peter M Edelbroek, Linda Holtman, Eleonora Aronica, Jan A Gorter, Heidrun Potschka. Neuropharmacology 2010
100
12



Pharmacological blockade of IL-1β/IL-1 receptor type 1 axis during epileptogenesis provides neuroprotection in two rat models of temporal lobe epilepsy.
F M Noe, N Polascheck, F Frigerio, M Bankstahl, T Ravizza, S Marchini, L Beltrame, C Reschke Banderó, W Löscher, A Vezzani. Neurobiol Dis 2013
117
12

Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.
Karin Borges, Marla Gearing, Dayna L McDermott, Amy B Smith, Antoine G Almonte, Bruce H Wainer, Raymond Dingledine. Exp Neurol 2003
297
12



The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus.
Asheebo Rojas, Paoula Gueorguieva, Nadia Lelutiu, Yi Quan, Renee Shaw, Raymond Dingledine. Neurobiol Dis 2014
22
54

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy.
Teresa Ravizza, Barbara Gagliardi, Francesco Noé, Karin Boer, Eleonora Aronica, Annamaria Vezzani. Neurobiol Dis 2008
455
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.