Derek S Welsbie, Zhiyong Yang, Yan Ge, Katherine L Mitchell, Xinrong Zhou, Scott E Martin, Cynthia A Berlinicke, Laszlo Hackler, John Fuller, Jie Fu, Li-hui Cao, Bing Han, Douglas Auld, Tian Xue, Syu-ichi Hirai, Lucie Germain, Caroline Simard-Bisson, Richard Blouin, Judy V Nguyen, Chung-ha O Davis, Raymond A Enke, Sanford L Boye, Shannath L Merbs, Nicholas Marsh-Armstrong, William W Hauswirth, Aaron DiAntonio, Robert W Nickells, James Inglese, Justin Hanes, King-Wai Yau, Harry A Quigley, Donald J Zack. Proc Natl Acad Sci U S A 2013
Times Cited: 153
Times Cited: 153
Times Cited
Times Co-cited
Similarity
DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury.
Trent A Watkins, Bei Wang, Sarah Huntwork-Rodriguez, Jing Yang, Zhiyu Jiang, Jeffrey Eastham-Anderson, Zora Modrusan, Joshua S Kaminker, Marc Tessier-Lavigne, Joseph W Lewcock. Proc Natl Acad Sci U S A 2013
Trent A Watkins, Bei Wang, Sarah Huntwork-Rodriguez, Jing Yang, Zhiyu Jiang, Jeffrey Eastham-Anderson, Zora Modrusan, Joshua S Kaminker, Marc Tessier-Lavigne, Joseph W Lewcock. Proc Natl Acad Sci U S A 2013
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A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration.
Bradley R Miller, Craig Press, Richard W Daniels, Yo Sasaki, Jeffrey Milbrandt, Aaron DiAntonio. Nat Neurosci 2009
Bradley R Miller, Craig Press, Richard W Daniels, Yo Sasaki, Jeffrey Milbrandt, Aaron DiAntonio. Nat Neurosci 2009
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DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity.
Arundhati Sengupta Ghosh, Bei Wang, Christine D Pozniak, Mark Chen, Ryan J Watts, Joseph W Lewcock. J Cell Biol 2011
Arundhati Sengupta Ghosh, Bei Wang, Christine D Pozniak, Mark Chen, Ryan J Watts, Joseph W Lewcock. J Cell Biol 2011
33
Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.
Derek S Welsbie, Katherine L Mitchell, Vinod Jaskula-Ranga, Valentin M Sluch, Zhiyong Yang, Jessica Kim, Eugen Buehler, Amit Patel, Scott E Martin, Ping-Wu Zhang,[...]. Neuron 2017
Derek S Welsbie, Katherine L Mitchell, Vinod Jaskula-Ranga, Valentin M Sluch, Zhiyong Yang, Jessica Kim, Eugen Buehler, Amit Patel, Scott E Martin, Ping-Wu Zhang,[...]. Neuron 2017
47
Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration.
Jung Eun Shin, Yongcheol Cho, Bogdan Beirowski, Jeffrey Milbrandt, Valeria Cavalli, Aaron DiAntonio. Neuron 2012
Jung Eun Shin, Yongcheol Cho, Bogdan Beirowski, Jeffrey Milbrandt, Valeria Cavalli, Aaron DiAntonio. Neuron 2012
29
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Claire E Le Pichon, William J Meilandt, Sara Dominguez, Hilda Solanoy, Han Lin, Hai Ngu, Alvin Gogineni, Arundhati Sengupta Ghosh, Zhiyu Jiang, Seung-Hye Lee,[...]. Sci Transl Med 2017
Claire E Le Pichon, William J Meilandt, Sara Dominguez, Hilda Solanoy, Han Lin, Hai Ngu, Alvin Gogineni, Arundhati Sengupta Ghosh, Zhiyu Jiang, Seung-Hye Lee,[...]. Sci Transl Med 2017
36
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death.
Kimberly A Fernandes, Jeffrey M Harder, Laura B Fornarola, Robert S Freeman, Abbot F Clark, Iok-Hou Pang, Simon W M John, Richard T Libby. Neurobiol Dis 2012
Kimberly A Fernandes, Jeffrey M Harder, Laura B Fornarola, Robert S Freeman, Abbot F Clark, Iok-Hou Pang, Simon W M John, Richard T Libby. Neurobiol Dis 2012
26
JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis.
Sarah Huntwork-Rodriguez, Bei Wang, Trent Watkins, Arundhati Sengupta Ghosh, Christine D Pozniak, Daisy Bustos, Kim Newton, Donald S Kirkpatrick, Joseph W Lewcock. J Cell Biol 2013
Sarah Huntwork-Rodriguez, Bei Wang, Trent Watkins, Arundhati Sengupta Ghosh, Christine D Pozniak, Daisy Bustos, Kim Newton, Donald S Kirkpatrick, Joseph W Lewcock. J Cell Biol 2013
27
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
Christine D Pozniak, Arundhati Sengupta Ghosh, Alvin Gogineni, Jesse E Hanson, Seung-Hye Lee, Jessica L Larson, Hilda Solanoy, Daisy Bustos, Hong Li, Hai Ngu,[...]. J Exp Med 2013
Christine D Pozniak, Arundhati Sengupta Ghosh, Alvin Gogineni, Jesse E Hanson, Seung-Hye Lee, Jessica L Larson, Hilda Solanoy, Daisy Bustos, Hong Li, Hai Ngu,[...]. J Exp Med 2013
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DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury.
Kimberly A Fernandes, Jeffrey M Harder, Simon W John, Peter Shrager, Richard T Libby. Neurobiol Dis 2014
Kimberly A Fernandes, Jeffrey M Harder, Simon W John, Peter Shrager, Richard T Libby. Neurobiol Dis 2014
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Pathological axonal death through a MAPK cascade that triggers a local energy deficit.
Jing Yang, Zhuhao Wu, Nicolas Renier, David J Simon, Kunihiro Uryu, David S Park, Peter A Greer, Cathy Tournier, Roger J Davis, Marc Tessier-Lavigne. Cell 2015
Jing Yang, Zhuhao Wu, Nicolas Renier, David J Simon, Kunihiro Uryu, David S Park, Peter A Greer, Cathy Tournier, Roger J Davis, Marc Tessier-Lavigne. Cell 2015
24
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway.
Kevin Kyungsuk Park, Kai Liu, Yang Hu, Patrice D Smith, Chen Wang, Bin Cai, Bengang Xu, Lauren Connolly, Ioannis Kramvis, Mustafa Sahin,[...]. Science 2008
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The DLK signalling pathway--a double-edged sword in neural development and regeneration.
Andrea Tedeschi, Frank Bradke. EMBO Rep 2013
Andrea Tedeschi, Frank Bradke. EMBO Rep 2013
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Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury.
Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A Collins. J Cell Biol 2010
Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A Collins. J Cell Biol 2010
22
Palmitoylation controls DLK localization, interactions and activity to ensure effective axonal injury signaling.
Sabrina M Holland, Kaitlin M Collura, Andrea Ketschek, Kentaro Noma, Toby A Ferguson, Yishi Jin, Gianluca Gallo, Gareth M Thomas. Proc Natl Acad Sci U S A 2016
Sabrina M Holland, Kaitlin M Collura, Andrea Ketschek, Kentaro Noma, Toby A Ferguson, Yishi Jin, Gianluca Gallo, Gareth M Thomas. Proc Natl Acad Sci U S A 2016
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Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.
Vera Valakh, Erin Frey, Elisabetta Babetto, Lauren J Walker, Aaron DiAntonio. Neurobiol Dis 2015
Vera Valakh, Erin Frey, Elisabetta Babetto, Lauren J Walker, Aaron DiAntonio. Neurobiol Dis 2015
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Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage.
Richard T Libby, Yan Li, Olga V Savinova, Joseph Barter, Richard S Smith, Robert W Nickells, Simon W M John. PLoS Genet 2005
Richard T Libby, Yan Li, Olga V Savinova, Joseph Barter, Richard S Smith, Robert W Nickells, Simon W M John. PLoS Genet 2005
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Axon regeneration requires a conserved MAP kinase pathway.
Marc Hammarlund, Paola Nix, Linda Hauth, Erik M Jorgensen, Michael Bastiani. Science 2009
Marc Hammarlund, Paola Nix, Linda Hauth, Erik M Jorgensen, Michael Bastiani. Science 2009
18
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3.
Fang Sun, Kevin K Park, Stephane Belin, Dongqing Wang, Tao Lu, Gang Chen, Kang Zhang, Cecil Yeung, Guoping Feng, Bruce A Yankner,[...]. Nature 2011
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17
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
Josiah Gerdts, Daniel W Summers, Jeffrey Milbrandt, Aaron DiAntonio. Neuron 2016
Josiah Gerdts, Daniel W Summers, Jeffrey Milbrandt, Aaron DiAntonio. Neuron 2016
17
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma.
Gareth R Howell, Richard T Libby, Tatjana C Jakobs, Richard S Smith, F Campbell Phalan, Joseph W Barter, Jessica M Barbay, Jeffrey K Marchant, Nagaraju Mahesh, Vittorio Porciatti,[...]. J Cell Biol 2007
Gareth R Howell, Richard T Libby, Tatjana C Jakobs, Richard S Smith, F Campbell Phalan, Joseph W Barter, Jessica M Barbay, Jeffrey K Marchant, Nagaraju Mahesh, Vittorio Porciatti,[...]. J Cell Biol 2007
16
Subtype-specific regeneration of retinal ganglion cells following axotomy: effects of osteopontin and mTOR signaling.
Xin Duan, Mu Qiao, Fengfeng Bei, In-Jung Kim, Zhigang He, Joshua R Sanes. Neuron 2015
Xin Duan, Mu Qiao, Fengfeng Bei, In-Jung Kim, Zhigang He, Joshua R Sanes. Neuron 2015
16
Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.
David J Simon, Jason Pitts, Nicholas T Hertz, Jing Yang, Yuya Yamagishi, Olav Olsen, Milica Tešić Mark, Henrik Molina, Marc Tessier-Lavigne. Cell 2016
David J Simon, Jason Pitts, Nicholas T Hertz, Jing Yang, Yuya Yamagishi, Olav Olsen, Milica Tešić Mark, Henrik Molina, Marc Tessier-Lavigne. Cell 2016
18
KLF family members regulate intrinsic axon regeneration ability.
Darcie L Moore, Murray G Blackmore, Ying Hu, Klaus H Kaestner, John L Bixby, Vance P Lemmon, Jeffrey L Goldberg. Science 2009
Darcie L Moore, Murray G Blackmore, Ying Hu, Klaus H Kaestner, John L Bixby, Vance P Lemmon, Jeffrey L Goldberg. Science 2009
14
JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells.
Kimberly A Fernandes, Jeffrey M Harder, Jessica Kim, Richard T Libby. Exp Eye Res 2013
Kimberly A Fernandes, Jeffrey M Harder, Jessica Kim, Richard T Libby. Exp Eye Res 2013
26
The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration.
Dong Yan, Zilu Wu, Andrew D Chisholm, Yishi Jin. Cell 2009
Dong Yan, Zilu Wu, Andrew D Chisholm, Yishi Jin. Cell 2009
14
SARM1 activation triggers axon degeneration locally via NAD⁺ destruction.
Josiah Gerdts, E J Brace, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt. Science 2015
Josiah Gerdts, E J Brace, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt. Science 2015
13
Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo.
Xiqun Chen, Margarita Rzhetskaya, Tatyana Kareva, Ross Bland, Matthew J During, A William Tank, Nikolai Kholodilov, Robert E Burke. J Neurosci 2008
Xiqun Chen, Margarita Rzhetskaya, Tatyana Kareva, Ross Bland, Matthew J During, A William Tank, Nikolai Kholodilov, Robert E Burke. J Neurosci 2008
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Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models.
Snahel Patel, Frederick Cohen, Brian J Dean, Kelly De La Torre, Gauri Deshmukh, Anthony A Estrada, Arundhati Sengupta Ghosh, Paul Gibbons, Amy Gustafson, Malcolm P Huestis,[...]. J Med Chem 2015
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27
Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult.
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Martin Larhammar, Sarah Huntwork-Rodriguez, Zhiyu Jiang, Hilda Solanoy, Arundhati Sengupta Ghosh, Bei Wang, Joshua S Kaminker, Kevin Huang, Jeffrey Eastham-Anderson, Michael Siu,[...]. Elife 2017
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Highwire restrains synaptic growth by attenuating a MAP kinase signal.
Catherine A Collins, Yogesh P Wairkar, Sylvia L Johnson, Aaron DiAntonio. Neuron 2006
Catherine A Collins, Yogesh P Wairkar, Sylvia L Johnson, Aaron DiAntonio. Neuron 2006
13
Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells.
Yang Hu, Kevin K Park, Liu Yang, Xin Wei, Qiang Yang, Kin-Sang Cho, Peter Thielen, Ann-Hwee Lee, Romain Cartoni, Laurie H Glimcher,[...]. Neuron 2012
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12
The number of people with glaucoma worldwide in 2010 and 2020.
H A Quigley, A T Broman. Br J Ophthalmol 2006
H A Quigley, A T Broman. Br J Ophthalmol 2006
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Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others.
Michael W Norsworthy, Fengfeng Bei, Riki Kawaguchi, Qing Wang, Nicholas M Tran, Yi Li, Benedikt Brommer, Yiming Zhang, Chen Wang, Joshua R Sanes,[...]. Neuron 2017
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14
Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons.
Meifan Chen, Cédric G Geoffroy, Hetty N Wong, Oliver Tress, Mallorie T Nguyen, Lawrence B Holzman, Yishi Jin, Binhai Zheng. Sci Rep 2016
Meifan Chen, Cédric G Geoffroy, Hetty N Wong, Oliver Tress, Mallorie T Nguyen, Lawrence B Holzman, Yishi Jin, Binhai Zheng. Sci Rep 2016
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SOCS3 deletion promotes optic nerve regeneration in vivo.
Patrice D Smith, Fang Sun, Kevin Kyungsuk Park, Bin Cai, Chen Wang, Kenichiro Kuwako, Irene Martinez-Carrasco, Lauren Connolly, Zhigang He. Neuron 2009
Patrice D Smith, Fang Sun, Kevin Kyungsuk Park, Bin Cai, Chen Wang, Kenichiro Kuwako, Irene Martinez-Carrasco, Lauren Connolly, Zhigang He. Neuron 2009
11
SCG10 is a JNK target in the axonal degeneration pathway.
Jung Eun Shin, Bradley R Miller, Elisabetta Babetto, Yongcheol Cho, Yo Sasaki, Shehzad Qayum, Emilie V Russler, Valeria Cavalli, Jeffrey Milbrandt, Aaron DiAntonio. Proc Natl Acad Sci U S A 2012
Jung Eun Shin, Bradley R Miller, Elisabetta Babetto, Yongcheol Cho, Yo Sasaki, Shehzad Qayum, Emilie V Russler, Valeria Cavalli, Jeffrey Milbrandt, Aaron DiAntonio. Proc Natl Acad Sci U S A 2012
11
An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK.
Yan Hao, Erin Frey, Choya Yoon, Hetty Wong, Douglas Nestorovski, Lawrence B Holzman, Roman J Giger, Aaron DiAntonio, Catherine Collins. Elife 2016
Yan Hao, Erin Frey, Choya Yoon, Hetty Wong, Douglas Nestorovski, Lawrence B Holzman, Roman J Giger, Aaron DiAntonio, Catherine Collins. Elife 2016
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The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex.
Syu-ichi Hirai, De Feng Cui, Takaki Miyata, Masaharu Ogawa, Hiroshi Kiyonari, Yoko Suda, Shinichi Aizawa, Yumi Banba, Shigeo Ohno. J Neurosci 2006
Syu-ichi Hirai, De Feng Cui, Takaki Miyata, Masaharu Ogawa, Hiroshi Kiyonari, Yoko Suda, Shinichi Aizawa, Yumi Banba, Shigeo Ohno. J Neurosci 2006
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ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion.
Yu-Wen Alvin Huang, Bo Zhou, Marius Wernig, Thomas C Südhof. Cell 2017
Yu-Wen Alvin Huang, Bo Zhou, Marius Wernig, Thomas C Südhof. Cell 2017
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MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.
Lauren J Walker, Daniel W Summers, Yo Sasaki, E J Brace, Jeffrey Milbrandt, Aaron DiAntonio. Elife 2017
Lauren J Walker, Daniel W Summers, Yo Sasaki, E J Brace, Jeffrey Milbrandt, Aaron DiAntonio. Elife 2017
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Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity.
Jeffrey L Goldberg, Juan S Espinosa, Youfeng Xu, Norman Davidson, Gregory T A Kovacs, Ben A Barres. Neuron 2002
Jeffrey L Goldberg, Juan S Espinosa, Youfeng Xu, Norman Davidson, Gregory T A Kovacs, Ben A Barres. Neuron 2002
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Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis.
Heather R Pelzel, Cassandra L Schlamp, Robert W Nickells. BMC Neurosci 2010
Heather R Pelzel, Cassandra L Schlamp, Robert W Nickells. BMC Neurosci 2010
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Neural activity promotes long-distance, target-specific regeneration of adult retinal axons.
Jung-Hwan A Lim, Benjamin K Stafford, Phong L Nguyen, Brian V Lien, Chen Wang, Katherine Zukor, Zhigang He, Andrew D Huberman. Nat Neurosci 2016
Jung-Hwan A Lim, Benjamin K Stafford, Phong L Nguyen, Brian V Lien, Chen Wang, Katherine Zukor, Zhigang He, Andrew D Huberman. Nat Neurosci 2016
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Bax-dependent and independent pathways of retinal ganglion cell death induced by different damaging stimuli.
Y Li, C L Schlamp, K P Poulsen, R W Nickells. Exp Eye Res 2000
Y Li, C L Schlamp, K P Poulsen, R W Nickells. Exp Eye Res 2000
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dSarm/Sarm1 is required for activation of an injury-induced axon death pathway.
Jeannette M Osterloh, Jing Yang, Timothy M Rooney, A Nicole Fox, Robert Adalbert, Eric H Powell, Amy E Sheehan, Michelle A Avery, Rachel Hackett, Mary A Logan,[...]. Science 2012
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Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.
Yih-Chung Tham, Xiang Li, Tien Y Wong, Harry A Quigley, Tin Aung, Ching-Yu Cheng. Ophthalmology 2014
Yih-Chung Tham, Xiang Li, Tien Y Wong, Harry A Quigley, Tin Aung, Ching-Yu Cheng. Ophthalmology 2014
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An axonal stress response pathway: degenerative and regenerative signaling by DLK.
Elham Asghari Adib, Laura J Smithson, Catherine A Collins. Curr Opin Neurobiol 2018
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Palmitoylation enables MAPK-dependent proteostasis of axon survival factors.
Daniel W Summers, Jeffrey Milbrandt, Aaron DiAntonio. Proc Natl Acad Sci U S A 2018
Daniel W Summers, Jeffrey Milbrandt, Aaron DiAntonio. Proc Natl Acad Sci U S A 2018
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Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning.
B A Barres, B E Silverstein, D P Corey, L L Chun. Neuron 1988
B A Barres, B E Silverstein, D P Corey, L L Chun. Neuron 1988
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.