Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan, H Christian Eberl, Anneloes Mensinga, Arie B Brinkman, Konstantin Lephikov, Udo Müller, Jörn Walter, Rolf Boelens, Hugo van Ingen, Heinrich Leonhardt, Thomas Carell, Michiel Vermeulen. Cell 2013
Times Cited: 677
Times Cited: 677
Times Cited
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Similarity
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
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5-Hydroxymethylcytosine is a predominantly stable DNA modification.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
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A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation.
Mario Iurlaro, Gabriella Ficz, David Oxley, Eun-Ang Raiber, Martin Bachman, Michael J Booth, Simon Andrews, Shankar Balasubramanian, Wolf Reik. Genome Biol 2013
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TET-mediated active DNA demethylation: mechanism, function and beyond.
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
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5-Formylcytosine can be a stable DNA modification in mammals.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Heather E Burgess, Mario Iurlaro, Wolf Reik, Adele Murrell, Shankar Balasubramanian. Nat Chem Biol 2015
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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
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Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.
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Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
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Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
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Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.
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Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.
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Human DNA methylomes at base resolution show widespread epigenomic differences.
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Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
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5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.
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Magnolia Bostick, Jong Kyong Kim, Pierre-Olivier Estève, Amander Clark, Sriharsa Pradhan, Steven E Jacobsen. Science 2007
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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
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TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.
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Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.
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Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.