A citation-based method for searching scientific literature

Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
Times Cited: 79







List of co-cited articles
790 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The N-end rule pathway and regulation by proteolysis.
Alexander Varshavsky. Protein Sci 2011
456
69

The N-end rule pathway.
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
254
58

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
102
58


N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
442
51

An essential role of N-terminal arginylation in cardiovascular development.
Yong Tae Kwon, Anna S Kashina, Ilia V Davydov, Rong-Gui Hu, Jee Young An, Jai Wha Seo, Fangyong Du, Alexander Varshavsky. Science 2002
248
46

Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
200
43

The N-terminal methionine of cellular proteins as a degradation signal.
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
121
40

The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators.
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
226
39


Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
61
44

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
Min Jae Lee, Takafumi Tasaki, Kayoko Moroi, Jee Young An, Sadao Kimura, Ilia V Davydov, Yong Tae Kwon. Proc Natl Acad Sci U S A 2005
186
32

The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions.
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
134
30

The degradation signal in a short-lived protein.
A Bachmair, A Varshavsky. Cell 1989
358
27

The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+proteases.
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
85
27


Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway.
Sang-Eun Park, Jeong-Mok Kim, Ok-Hee Seok, Hanna Cho, Brandon Wadas, Seon-Young Kim, Alexander Varshavsky, Cheol-Sang Hwang. Science 2015
95
25

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Hyunjoo Cha-Molstad, Ki Sa Sung, Joonsung Hwang, Kyoung A Kim, Ji Eun Yu, Young Dong Yoo, Jun Min Jang, Dong Hoon Han, Michael Molstad, Jung Gi Kim,[...]. Nat Cell Biol 2015
143
25

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
112
25

The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
51
37

Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases.
Woo Suk Choi, Byung-Cheon Jeong, Yoo Jin Joo, Myeong-Ryeol Lee, Joon Kim, Michael J Eck, Hyun Kyu Song. Nat Struct Mol Biol 2010
101
24

N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
221
24

The N-end rule in bacteria.
J W Tobias, T E Shrader, G Rocap, A Varshavsky. Science 1991
422
21

Structural basis of substrate recognition and specificity in the N-end rule pathway.
Edna Matta-Camacho, Guennadi Kozlov, Flora F Li, Kalle Gehring. Nat Struct Mol Biol 2010
75
22

PINK1 is degraded through the N-end rule pathway.
Koji Yamano, Richard J Youle. Autophagy 2013
385
21

Ubiquitin fusion technique and related methods.
Alexander Varshavsky. Methods Enzymol 2005
86
20

Glutamine-specific N-terminal amidase, a component of the N-end rule pathway.
Haiqing Wang, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Mol Cell 2009
68
23

Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen.
Emmanuelle Graciet, Rong-Gui Hu, Konstantin Piatkov, Joon Haeng Rhee, Erich M Schwarz, Alexander Varshavsky. Proc Natl Acad Sci U S A 2006
72
20

The N-end rule pathway is a sensor of heme.
Rong-Gui Hu, Haiqing Wang, Zanxian Xia, Alexander Varshavsky. Proc Natl Acad Sci U S A 2008
87
18


The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.
Cheol-Sang Hwang, Anna Shemorry, Daniel Auerbach, Alexander Varshavsky. Nat Cell Biol 2010
102
18

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.
Takafumi Tasaki, Lubbertus C F Mulder, Akihiro Iwamatsu, Min Jae Lee, Ilia V Davydov, Alexander Varshavsky, Mark Muesing, Yong Tae Kwon. Mol Cell Biol 2005
232
18


The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
265
17

Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes.
Min Jae Lee, Dong Eun Kim, Adriana Zakrzewska, Young Dong Yoo, Su-Hyeon Kim, Sung Tae Kim, Jai Wha Seo, Young Sook Lee, Gerald W Dorn, Uhtaek Oh,[...]. J Biol Chem 2012
38
36

Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome).
Martin Zenker, Julia Mayerle, Markus M Lerch, Andreas Tagariello, Klaus Zerres, Peter R Durie, Matthias Beier, Georg Hülskamp, Celina Guzman, Helga Rehder,[...]. Nat Genet 2005
175
17

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.
Mark Ditzel, Rebecca Wilson, Tencho Tenev, Anna Zachariou, Angela Paul, Emma Deas, Pascal Meier. Nat Cell Biol 2003
200
17

Discovery of cellular regulation by protein degradation.
Alexander Varshavsky. J Biol Chem 2008
74
17

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1.
Jarrod W Heck, Samantha K Cheung, Randolph Y Hampton. Proc Natl Acad Sci U S A 2010
206
16

Arginyltransferase is an ATP-independent self-regulating enzyme that forms distinct functional complexes in vivo.
Junling Wang, Xuemei Han, Sougata Saha, Tao Xu, Reena Rai, Fangliang Zhang, Yuri I Wolf, Alexey Wolfson, John R Yates, Anna Kashina. Chem Biol 2011
53
24


The substrate recognition domains of the N-end rule pathway.
Takafumi Tasaki, Adriana Zakrzewska, Drew D Dudgeon, Yonghua Jiang, John S Lazo, Yong Tae Kwon. J Biol Chem 2009
93
16


The N-end rule pathway for regulated proteolysis: prokaryotic and eukaryotic strategies.
Axel Mogk, Ronny Schmidt, Bernd Bukau. Trends Cell Biol 2007
193
15


Arginylation of beta-actin regulates actin cytoskeleton and cell motility.
Marina Karakozova, Marina Kozak, Catherine C L Wong, Aaron O Bailey, John R Yates, Alexander Mogilner, Henry Zebroski, Anna Kashina. Science 2006
196
15

Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Min Kyung Kim, Sun Joo Oh, Byung-Gil Lee, Hyun Kyu Song. Proc Natl Acad Sci U S A 2016
21
57

Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway.
Jang-Hyun Oh, Ju-Yeon Hyun, Alexander Varshavsky. Proc Natl Acad Sci U S A 2017
34
35

Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway.
Jeong-Mok Kim, Ok-Hee Seok, Shinyeong Ju, Ji-Eun Heo, Jeonghun Yeom, Da-Som Kim, Joo-Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol-Sang Hwang. Science 2018
48
25

Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases.
Qing Xiao, Feiran Zhang, Benjamin A Nacev, Jun O Liu, Dehua Pei. Biochemistry 2010
108
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.