A citation-based method for searching scientific literature

Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang, Ya'an Kang, Jason B Fleming, Nabeel Bardeesy, John M Asara, Marcia C Haigis, Ronald A DePinho, Lewis C Cantley, Alec C Kimmelman. Nature 2013
Times Cited: 1099







List of co-cited articles
1197 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
27

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
26

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
732
18

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
17

Glutamine addiction: a new therapeutic target in cancer.
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
16

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
David R Wise, Ralph J DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B McMahon,[...]. Proc Natl Acad Sci U S A 2008
16

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
900
15

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
15

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
14

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Christian M Metallo, Paulo A Gameiro, Eric L Bell, Katherine R Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M Jewell, Zachary R Johnson, Darrell J Irvine, Leonard Guarente,[...]. Nature 2011
13

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
13

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
529
12

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
Jurre J Kamphorst, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, George Miller, Jeffrey A Drebin, Dafna Bar-Sagi,[...]. Cancer Res 2015
420
12

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.
Jurre J Kamphorst, Justin R Cross, Jing Fan, Elisa de Stanchina, Robin Mathew, Eileen P White, Craig B Thompson, Joshua D Rabinowitz. Proc Natl Acad Sci U S A 2013
412
11

On the origin of cancer cells.
O WARBURG. Science 1956
11

Glutamine and cancer: cell biology, physiology, and clinical opportunities.
Christopher T Hensley, Ajla T Wasti, Ralph J DeBerardinis. J Clin Invest 2013
668
10


Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
10

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Shawn M Davidson, Thales Papagiannakopoulos, Benjamin A Olenchock, Julia E Heyman, Mark A Keibler, Alba Luengo, Matthew R Bauer, Abhishek K Jha, James P O'Brien, Kerry A Pierce,[...]. Cell Metab 2016
430
10

Pancreatic cancers require autophagy for tumor growth.
Shenghong Yang, Xiaoxu Wang, Gianmarco Contino, Marc Liesa, Ergun Sahin, Haoqiang Ying, Alexandra Bause, Yinghua Li, Jayne M Stommel, Giacomo Dell'antonio,[...]. Genes Dev 2011
929
10

Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Michael A Badgley, Daniel M Kremer, H Carlo Maurer, Kathleen E DelGiorno, Ho-Joon Lee, Vinee Purohit, Irina R Sagalovskiy, Alice Ma, Jonathan Kapilian, Christina E M Firl,[...]. Science 2020
237
10

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Lucas B Sullivan, Dan Y Gui, Aaron M Hosios, Lauren N Bush, Elizaveta Freinkman, Matthew G Vander Heiden. Cell 2015
551
9

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
625
9

Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.
Alex J Bott, Jianliang Shen, Claudia Tonelli, Le Zhan, Nithya Sivaram, Ya-Ping Jiang, Xufen Yu, Vrushank Bhatt, Eric Chiles, Hua Zhong,[...]. Cell Rep 2019
36
25

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
525
9

Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
555
9


A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells.
Hee Chan Yoo, Seung Joon Park, Miso Nam, Juwon Kang, Kibum Kim, Joo Hye Yeo, Joon-Ki Kim, Yunkyung Heo, Hee Seung Lee, Myeong Youl Lee,[...]. Cell Metab 2020
87
10

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Amanda Truong, Sophia S Schuman, Jill E Shea, Michael T Seipp, Jeffrey T Yap,[...]. Nat Med 2019
265
8

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Kirsten L Bryant, Clint A Stalnecker, Daniel Zeitouni, Jennifer E Klomp, Sen Peng, Andrey P Tikunov, Venugopal Gunda, Mariaelena Pierobon, Andrew M Waters, Samuel D George,[...]. Nat Med 2019
266
8

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
David R Wise, Patrick S Ward, Jessica E S Shay, Justin R Cross, Joshua J Gruber, Uma M Sachdeva, Jesse M Platt, Raymond G DeMatteo, M Celeste Simon, Craig B Thompson. Proc Natl Acad Sci U S A 2011
656
8

Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Andrew R Mullen, William W Wheaton, Eunsook S Jin, Pei-Hsuan Chen, Lucas B Sullivan, Tzuling Cheng, Youfeng Yang, W Marston Linehan, Navdeep S Chandel, Ralph J DeBerardinis. Nature 2011
810
8

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.
Douglas E Biancur, Joao A Paulo, Beata Małachowska, Maria Quiles Del Rey, Cristovão M Sousa, Xiaoxu Wang, Albert S W Sohn, Gerald C Chu, Steven P Gygi, J Wade Harper,[...]. Nat Commun 2017
137
8

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
Anne Le, Andrew N Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J Rojas, Barbara S Slusher, Haixia Zhang,[...]. Cell Metab 2012
683
8

Glutamine Metabolism in Cancer: Understanding the Heterogeneity.
Ahmad A Cluntun, Michael J Lukey, Richard A Cerione, Jason W Locasale. Trends Cancer 2017
240
8

α-Ketoglutarate links p53 to cell fate during tumour suppression.
John P Morris, Jossie J Yashinskie, Richard Koche, Rohit Chandwani, Sha Tian, Chi-Chao Chen, Timour Baslan, Zoran S Marinkovic, Francisco J Sánchez-Rivera, Steven D Leach,[...]. Nature 2019
85
9

Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer.
Christopher J Halbrook, Costas A Lyssiotis. Cancer Cell 2017
180
8

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Andrea Viale, Piergiorgio Pettazzoni, Costas A Lyssiotis, Haoqiang Ying, Nora Sánchez, Matteo Marchesini, Alessandro Carugo, Tessa Green, Sahil Seth, Virginia Giuliani,[...]. Nature 2014
706
8

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.
Daniela Gaglio, Christian M Metallo, Paulo A Gameiro, Karsten Hiller, Lara Sala Danna, Chiara Balestrieri, Lilia Alberghina, Gregory Stephanopoulos, Ferdinando Chiaradonna. Mol Syst Biol 2011
324
8

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Ralph J DeBerardinis, Julian J Lum, Georgia Hatzivassiliou, Craig B Thompson. Cell Metab 2008
8

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Gina M DeNicola, Florian A Karreth, Timothy J Humpton, Aarthi Gopinathan, Cong Wei, Kristopher Frese, Dipti Mangal, Kenneth H Yu, Charles J Yeo, Eric S Calhoun,[...]. Nature 2011
8

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
7

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
7

Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.
Jian-Bin Wang, Jon W Erickson, Reina Fuji, Sekar Ramachandran, Ping Gao, Ramani Dinavahi, Kristin F Wilson, Andre L B Ambrosio, Sandra M G Dias, Chi V Dang,[...]. Cancer Cell 2010
551
7

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
517
7

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
994
7

KRAS: feeding pancreatic cancer proliferation.
Kirsten L Bryant, Joseph D Mancias, Alec C Kimmelman, Channing J Der. Trends Biochem Sci 2014
402
7

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
268
7

Glutaminolysis: A Hallmark of Cancer Metabolism.
Lifeng Yang, Sriram Venneti, Deepak Nagrath. Annu Rev Biomed Eng 2017
230
7

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Jared R Mayers, Margaret E Torrence, Laura V Danai, Thales Papagiannakopoulos, Shawn M Davidson, Matthew R Bauer, Allison N Lau, Brian W Ji, Purushottam D Dixit, Aaron M Hosios,[...]. Science 2016
300
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.