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Times Cited: 487
Times Cited: 487
Times Cited
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Similarity
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
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Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
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Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
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Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
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Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.
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Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
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Itaconic acid is a mammalian metabolite induced during macrophage activation.
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Itaconate: the poster child of metabolic reprogramming in macrophage function.
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Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages.
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Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.
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The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
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S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate.
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The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.
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The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
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4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects.
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Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.
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Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.
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Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.
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TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
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Itaconate, an isocitrate lyase-directed inhibitor in Pseudomonas indigofera.
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Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.
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9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.