Yun Chen, Gerald W Dorn. Science 2013
Times Cited: 694
Times Cited: 694
Times Cited
Times Co-cited
Similarity
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
33
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
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Mitofusin 2 tethers endoplasmic reticulum to mitochondria.
Olga Martins de Brito, Luca Scorrano. Nature 2008
Olga Martins de Brito, Luca Scorrano. Nature 2008
26
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
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Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice.
Guohua Gong, Moshi Song, Gyorgy Csordas, Daniel P Kelly, Scot J Matkovich, Gerald W Dorn. Science 2015
Guohua Gong, Moshi Song, Gyorgy Csordas, Daniel P Kelly, Scot J Matkovich, Gerald W Dorn. Science 2015
20
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
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Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A.
Stephan Züchner, Irina V Mersiyanova, Maria Muglia, Nisrine Bissar-Tadmouri, Julie Rochelle, Elena L Dadali, Mario Zappia, Eva Nelis, Alessandra Patitucci, Jan Senderek,[...]. Nat Genet 2004
Stephan Züchner, Irina V Mersiyanova, Maria Muglia, Nisrine Bissar-Tadmouri, Julie Rochelle, Elena L Dadali, Mario Zappia, Eva Nelis, Alessandra Patitucci, Jan Senderek,[...]. Nat Genet 2004
17
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
17
Ubiquitin is phosphorylated by PINK1 to activate parkin.
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
17
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy.
Matthew E Gegg, J Mark Cooper, Kai-Yin Chau, Manuel Rojo, Anthony H V Schapira, Jan-Willem Taanman. Hum Mol Genet 2010
Matthew E Gegg, J Mark Cooper, Kai-Yin Chau, Manuel Rojo, Anthony H V Schapira, Jan-Willem Taanman. Hum Mol Genet 2010
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Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.
Yongjie Wei, Wei-Chung Chiang, Rhea Sumpter, Prashant Mishra, Beth Levine. Cell 2017
Yongjie Wei, Wei-Chung Chiang, Rhea Sumpter, Prashant Mishra, Beth Levine. Cell 2017
17
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.
Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto, Shungo Hikoso, Toshihiro Takeda, Takafumi Oka, Hiroki Yasui, Hiromichi Ueda, Yasuhiro Akazawa, Hiroyuki Nakayama,[...]. Nat Commun 2015
Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto, Shungo Hikoso, Toshihiro Takeda, Takafumi Oka, Hiroki Yasui, Hiromichi Ueda, Yasuhiro Akazawa, Hiroyuki Nakayama,[...]. Nat Commun 2015
16
Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain.
Yusuke Kageyama, Masahiko Hoshijima, Kinya Seo, Djahida Bedja, Polina Sysa-Shah, Shaida A Andrabi, Weiran Chen, Ahmet Höke, Valina L Dawson, Ted M Dawson,[...]. EMBO J 2014
Yusuke Kageyama, Masahiko Hoshijima, Kinya Seo, Djahida Bedja, Polina Sysa-Shah, Shaida A Andrabi, Weiran Chen, Ahmet Höke, Valina L Dawson, Ted M Dawson,[...]. EMBO J 2014
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A regulatory signaling loop comprising the PGAM5 phosphatase and CK2 controls receptor-mediated mitophagy.
Guo Chen, Zhe Han, Du Feng, Yanfang Chen, Linbo Chen, Hao Wu, Li Huang, Changqian Zhou, Xiangyu Cai, Changying Fu,[...]. Mol Cell 2014
Guo Chen, Zhe Han, Du Feng, Yanfang Chen, Linbo Chen, Hao Wu, Li Huang, Changqian Zhou, Xiangyu Cai, Changying Fu,[...]. Mol Cell 2014
16
Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
Alicia M Pickrell, Richard J Youle. Neuron 2015
16
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
Yvette C Wong, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2014
Yvette C Wong, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2014
15
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
14
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
14
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy.
Ming Chen, Ziheng Chen, Yueying Wang, Zheng Tan, Chongzhuo Zhu, Yanjun Li, Zhe Han, Linbo Chen, Ruize Gao, Lei Liu,[...]. Autophagy 2016
Ming Chen, Ziheng Chen, Yueying Wang, Zheng Tan, Chongzhuo Zhu, Yanjun Li, Zhe Han, Linbo Chen, Ruize Gao, Lei Liu,[...]. Autophagy 2016
14
13
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
13
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
13
Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress.
Yoshiyuki Ikeda, Akihiro Shirakabe, Yasuhiro Maejima, Peiyong Zhai, Sebastiano Sciarretta, Jessica Toli, Masatoshi Nomura, Katsuyoshi Mihara, Kensuke Egashira, Mitsuru Ohishi,[...]. Circ Res 2015
Yoshiyuki Ikeda, Akihiro Shirakabe, Yasuhiro Maejima, Peiyong Zhai, Sebastiano Sciarretta, Jessica Toli, Masatoshi Nomura, Katsuyoshi Mihara, Kensuke Egashira, Mitsuru Ohishi,[...]. Circ Res 2015
13
ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy.
Wenxian Wu, Weili Tian, Zhe Hu, Guo Chen, Lei Huang, Wen Li, Xingli Zhang, Peng Xue, Changqian Zhou, Lei Liu,[...]. EMBO Rep 2014
Wenxian Wu, Weili Tian, Zhe Hu, Guo Chen, Lei Huang, Wen Li, Xingli Zhang, Peng Xue, Changqian Zhou, Lei Liu,[...]. EMBO Rep 2014
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Microtubule-associated protein 1 light chain 3 (LC3) interacts with Bnip3 protein to selectively remove endoplasmic reticulum and mitochondria via autophagy.
Rita A Hanna, Melissa N Quinsay, Amabel M Orogo, Kayla Giang, Shivaji Rikka, Åsa B Gustafsson. J Biol Chem 2012
Rita A Hanna, Melissa N Quinsay, Amabel M Orogo, Kayla Giang, Shivaji Rikka, Åsa B Gustafsson. J Biol Chem 2012
13
Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
13
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
13
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.
Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J LaVoie, Thomas L Schwarz. Cell 2011
Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J LaVoie, Thomas L Schwarz. Cell 2011
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Mitochondrial fusion is essential for organelle function and cardiac homeostasis.
Yun Chen, Yingqiu Liu, Gerald W Dorn. Circ Res 2011
Yun Chen, Yingqiu Liu, Gerald W Dorn. Circ Res 2011
13
Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum-mitochondria tether.
Deborah Naon, Marta Zaninello, Marta Giacomello, Tatiana Varanita, Francesca Grespi, Sowmya Lakshminaranayan, Annalisa Serafini, Martina Semenzato, Stephanie Herkenne, Maria Isabel Hernández-Alvarez,[...]. Proc Natl Acad Sci U S A 2016
Deborah Naon, Marta Zaninello, Marta Giacomello, Tatiana Varanita, Francesca Grespi, Sowmya Lakshminaranayan, Annalisa Serafini, Martina Semenzato, Stephanie Herkenne, Maria Isabel Hernández-Alvarez,[...]. Proc Natl Acad Sci U S A 2016
13
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
13
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
Andrew W Greene, Karl Grenier, Miguel A Aguileta, Stephanie Muise, Rasoul Farazifard, M Emdadul Haque, Heidi M McBride, David S Park, Edward A Fon. EMBO Rep 2012
Andrew W Greene, Karl Grenier, Miguel A Aguileta, Stephanie Muise, Rasoul Farazifard, M Emdadul Haque, Heidi M McBride, David S Park, Edward A Fon. EMBO Rep 2012
13
Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts.
Moshi Song, Katsuyoshi Mihara, Yun Chen, Luca Scorrano, Gerald W Dorn. Cell Metab 2015
Moshi Song, Katsuyoshi Mihara, Yun Chen, Luca Scorrano, Gerald W Dorn. Cell Metab 2015
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Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
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Essential role for Nix in autophagic maturation of erythroid cells.
Hector Sandoval, Perumal Thiagarajan, Swapan K Dasgupta, Armin Schumacher, Josef T Prchal, Min Chen, Jin Wang. Nature 2008
Hector Sandoval, Perumal Thiagarajan, Swapan K Dasgupta, Armin Schumacher, Josef T Prchal, Min Chen, Jin Wang. Nature 2008
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FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
Wenxian Wu, Chunxia Lin, Keng Wu, Lei Jiang, Xiaojing Wang, Wen Li, Haixia Zhuang, Xingliang Zhang, Hao Chen, Shupeng Li,[...]. EMBO J 2016
Wenxian Wu, Chunxia Lin, Keng Wu, Lei Jiang, Xiaojing Wang, Wen Li, Haixia Zhuang, Xingliang Zhang, Hao Chen, Shupeng Li,[...]. EMBO J 2016
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Mitochondrial fission facilitates the selective mitophagy of protein aggregates.
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
12
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
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ER tubules mark sites of mitochondrial division.
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
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MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.
Agostinho G Rocha, Antonietta Franco, Andrzej M Krezel, Jeanne M Rumsey, Justin M Alberti, William C Knight, Nikolaos Biris, Emmanouil Zacharioudakis, James W Janetka, Robert H Baloh,[...]. Science 2018
Agostinho G Rocha, Antonietta Franco, Andrzej M Krezel, Jeanne M Rumsey, Justin M Alberti, William C Knight, Nikolaos Biris, Emmanouil Zacharioudakis, James W Janetka, Robert H Baloh,[...]. Science 2018
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The pathways of mitophagy for quality control and clearance of mitochondria.
G Ashrafi, T L Schwarz. Cell Death Differ 2013
G Ashrafi, T L Schwarz. Cell Death Differ 2013
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Mitochondrial dynamics, mitophagy and cardiovascular disease.
César Vásquez-Trincado, Ivonne García-Carvajal, Christian Pennanen, Valentina Parra, Joseph A Hill, Beverly A Rothermel, Sergio Lavandero. J Physiol 2016
César Vásquez-Trincado, Ivonne García-Carvajal, Christian Pennanen, Valentina Parra, Joseph A Hill, Beverly A Rothermel, Sergio Lavandero. J Physiol 2016
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Nix is a selective autophagy receptor for mitochondrial clearance.
Ivana Novak, Vladimir Kirkin, David G McEwan, Ji Zhang, Philipp Wild, Alexis Rozenknop, Vladimir Rogov, Frank Löhr, Doris Popovic, Angelo Occhipinti,[...]. EMBO Rep 2010
Ivana Novak, Vladimir Kirkin, David G McEwan, Ji Zhang, Philipp Wild, Alexis Rozenknop, Vladimir Rogov, Frank Löhr, Doris Popovic, Angelo Occhipinti,[...]. EMBO Rep 2010
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Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation.
Angelika S Rambold, Brenda Kostelecky, Natalie Elia, Jennifer Lippincott-Schwartz. Proc Natl Acad Sci U S A 2011
Angelika S Rambold, Brenda Kostelecky, Natalie Elia, Jennifer Lippincott-Schwartz. Proc Natl Acad Sci U S A 2011
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.