Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
Times Cited: 101
Times Cited: 101
Times Cited
Times Co-cited
Similarity
Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures.
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
48
34
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
32
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells.
Bastian Zimmer, Gabsang Lee, Nina V Balmer, Kesavan Meganathan, Agapios Sachinidis, Lorenz Studer, Marcel Leist. Environ Health Perspect 2012
Bastian Zimmer, Gabsang Lee, Nina V Balmer, Kesavan Meganathan, Agapios Sachinidis, Lorenz Studer, Marcel Leist. Environ Health Perspect 2012
41
Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line.
Diana Scholz, Dominik Pöltl, Andreas Genewsky, Matthias Weng, Tanja Waldmann, Stefan Schildknecht, Marcel Leist. J Neurochem 2011
Diana Scholz, Dominik Pöltl, Andreas Genewsky, Matthias Weng, Tanja Waldmann, Stefan Schildknecht, Marcel Leist. J Neurochem 2011
28
Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
34
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
26
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
26
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
31
Neurobehavioural effects of developmental toxicity.
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
25
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
26
Compound selection for in vitro modeling of developmental neurotoxicity.
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
40
Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts.
Christoph van Thriel, Remco H S Westerink, Christian Beste, Ambuja S Bale, Pamela J Lein, Marcel Leist. Neurotoxicology 2012
Christoph van Thriel, Remco H S Westerink, Christian Beste, Ambuja S Bale, Pamela J Lein, Marcel Leist. Neurotoxicology 2012
33
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome.
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
30
Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity.
Kristen R Ryan, Oksana Sirenko, Fred Parham, Jui-Hua Hsieh, Evan F Cromwell, Raymond R Tice, Mamta Behl. Neurotoxicology 2016
Kristen R Ryan, Oksana Sirenko, Fred Parham, Jui-Hua Hsieh, Evan F Cromwell, Raymond R Tice, Mamta Behl. Neurotoxicology 2016
26
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+).
A K Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, S Jagtap, J Meiser, G Leparc,[...]. Cell Death Dis 2014
A K Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, S Jagtap, J Meiser, G Leparc,[...]. Cell Death Dis 2014
29
The dawning of a new age of toxicology.
Marcel Leist, Thomas Hartung, Pierluigi Nicotera. ALTEX 2008
Marcel Leist, Thomas Hartung, Pierluigi Nicotera. ALTEX 2008
21
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, S Julien, K H Krause, C van Thriel, J G Hengstler,[...]. Arch Toxicol 2014
B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, S Julien, K H Krause, C van Thriel, J G Hengstler,[...]. Arch Toxicol 2014
36
Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro.
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
25
Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases.
Stefan Schildknecht, Christiaan Karreman, Dominik Pöltl, Liudmila Efrémova, Cornelius Kullmann, Simon Gutbier, Anne Krug, Diana Scholz, Hanne R Gerding, Marcel Leist. ALTEX 2013
Stefan Schildknecht, Christiaan Karreman, Dominik Pöltl, Liudmila Efrémova, Cornelius Kullmann, Simon Gutbier, Anne Krug, Diana Scholz, Hanne R Gerding, Marcel Leist. ALTEX 2013
40
Consensus report on the future of animal-free systemic toxicity testing.
Marcel Leist, Nina Hasiwa, Costanza Rovida, Mardas Daneshian, David Basketter, Ian Kimber, Harvey Clewell, Tilman Gocht, Alan Goldberg, Francois Busquet,[...]. ALTEX 2014
Marcel Leist, Nina Hasiwa, Costanza Rovida, Mardas Daneshian, David Basketter, Ian Kimber, Harvey Clewell, Tilman Gocht, Alan Goldberg, Francois Busquet,[...]. ALTEX 2014
18
OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
31
Developmental neurotoxicity testing in vitro: models for assessing chemical effects on neurite outgrowth.
Nicholas M Radio, William R Mundy. Neurotoxicology 2008
Nicholas M Radio, William R Mundy. Neurotoxicology 2008
17
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
17
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
D Rice, S Barone. Environ Health Perspect 2000
D Rice, S Barone. Environ Health Perspect 2000
17
Putative adverse outcome pathways relevant to neurotoxicity.
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
24
Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants.
Lisa Hoelting, Stefanie Klima, Christiaan Karreman, Marianna Grinberg, Johannes Meisig, Margit Henry, Tamara Rotshteyn, Jörg Rahnenführer, Nils Blüthgen, Agapios Sachinidis,[...]. Stem Cells Transl Med 2016
Lisa Hoelting, Stefanie Klima, Christiaan Karreman, Marianna Grinberg, Johannes Meisig, Margit Henry, Tamara Rotshteyn, Jörg Rahnenführer, Nils Blüthgen, Agapios Sachinidis,[...]. Stem Cells Transl Med 2016
37
Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events.
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
33
Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H Piersma,[...]. ALTEX 2018
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H Piersma,[...]. ALTEX 2018
20
Food for thought ... considerations and guidelines for basic test method descriptions in toxicology.
Marcel Leist, Liudmila Efremova, Christiaan Karreman. ALTEX 2010
Marcel Leist, Liudmila Efremova, Christiaan Karreman. ALTEX 2010
36
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing.
Philipp B Kuegler, Bastian Zimmer, Tanja Waldmann, Birte Baudis, Sten Ilmjärv, Jürgen Hescheler, Phil Gaughwin, Patrik Brundin, William Mundy, Anna K Bal-Price,[...]. ALTEX 2010
Philipp B Kuegler, Bastian Zimmer, Tanja Waldmann, Birte Baudis, Sten Ilmjärv, Jürgen Hescheler, Phil Gaughwin, Patrik Brundin, William Mundy, Anna K Bal-Price,[...]. ALTEX 2010
19
Developmental neurotoxicity testing: a path forward.
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
22
Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis.
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
21
mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach.
Helena T Hogberg, Agnieszka Kinsner-Ovaskainen, Sandra Coecke, Thomas Hartung, Anna K Bal-Price. Toxicol Sci 2010
Helena T Hogberg, Agnieszka Kinsner-Ovaskainen, Sandra Coecke, Thomas Hartung, Anna K Bal-Price. Toxicol Sci 2010
24
Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth.
Joshua A Harrill, Theresa M Freudenrich, Brian L Robinette, William R Mundy. Toxicol Appl Pharmacol 2011
Joshua A Harrill, Theresa M Freudenrich, Brian L Robinette, William R Mundy. Toxicol Appl Pharmacol 2011
30
Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons.
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
34
Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.
Tanja Waldmann, Eugen Rempel, Nina V Balmer, André König, Raivo Kolde, John Antonydas Gaspar, Margit Henry, Jürgen Hescheler, Agapios Sachinidis, Jörg Rahnenführer,[...]. Chem Res Toxicol 2014
Tanja Waldmann, Eugen Rempel, Nina V Balmer, André König, Raivo Kolde, John Antonydas Gaspar, Margit Henry, Jürgen Hescheler, Agapios Sachinidis, Jörg Rahnenführer,[...]. Chem Res Toxicol 2014
18
Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
34
A high-throughput approach to identify specific neurotoxicants/ developmental toxicants in human neuronal cell function assays.
Johannes Delp, Simon Gutbier, Stefanie Klima, Lisa Hoelting, Kevin Pinto-Gil, Jui-Hua Hsieh, Michael Aichem, Karsten Klein, Falk Schreiber, Raymond R Tice,[...]. ALTEX 2018
Johannes Delp, Simon Gutbier, Stefanie Klima, Lisa Hoelting, Kevin Pinto-Gil, Jui-Hua Hsieh, Michael Aichem, Karsten Klein, Falk Schreiber, Raymond R Tice,[...]. ALTEX 2018
53
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing.
B Zimmer, P B Kuegler, B Baudis, A Genewsky, V Tanavde, W Koh, B Tan, T Waldmann, S Kadereit, M Leist. Cell Death Differ 2011
B Zimmer, P B Kuegler, B Baudis, A Genewsky, V Tanavde, W Koh, B Tan, T Waldmann, S Kadereit, M Leist. Cell Death Differ 2011
18
Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway.
Julie Lotharius, Jeppe Falsig, Johan van Beek, Sarah Payne, Ralf Dringen, Patrik Brundin, Marcel Leist. J Neurosci 2005
Julie Lotharius, Jeppe Falsig, Johan van Beek, Sarah Payne, Ralf Dringen, Patrik Brundin, Marcel Leist. J Neurosci 2005
14
Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling.
Nadine Dreser, Bastian Zimmer, Christian Dietz, Elena Sügis, Giorgia Pallocca, Johanna Nyffeler, Johannes Meisig, Nils Blüthgen, Michael R Berthold, Tanja Waldmann,[...]. Neurotoxicology 2015
Nadine Dreser, Bastian Zimmer, Christian Dietz, Elena Sügis, Giorgia Pallocca, Johanna Nyffeler, Johannes Meisig, Nils Blüthgen, Michael R Berthold, Tanja Waldmann,[...]. Neurotoxicology 2015
66
In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities.
Béla Z Schmidt, Martin Lehmann, Simon Gutbier, Erastus Nembo, Sabrina Noel, Lena Smirnova, Anna Forsby, Jürgen Hescheler, Hasan X Avci, Thomas Hartung,[...]. Arch Toxicol 2017
Béla Z Schmidt, Martin Lehmann, Simon Gutbier, Erastus Nembo, Sabrina Noel, Lena Smirnova, Anna Forsby, Jürgen Hescheler, Hasan X Avci, Thomas Hartung,[...]. Arch Toxicol 2017
16
Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice.
Marcel Leist, Thomas Hartung. Arch Toxicol 2013
Marcel Leist, Thomas Hartung. Arch Toxicol 2013
13
Meeting report: alternatives for developmental neurotoxicity testing.
Pamela Lein, Paul Locke, Alan Goldberg. Environ Health Perspect 2007
Pamela Lein, Paul Locke, Alan Goldberg. Environ Health Perspect 2007
16
Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells.
Stefan Schildknecht, Dominik Pöltl, Daniel M Nagel, Florian Matt, Diana Scholz, Julie Lotharius, Nathalie Schmieg, Alberto Salvo-Vargas, Marcel Leist. Toxicol Appl Pharmacol 2009
Stefan Schildknecht, Dominik Pöltl, Daniel M Nagel, Florian Matt, Diana Scholz, Julie Lotharius, Nathalie Schmieg, Alberto Salvo-Vargas, Marcel Leist. Toxicol Appl Pharmacol 2009
17
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.
Nina V Balmer, Stefanie Klima, Eugen Rempel, Violeta N Ivanova, Raivo Kolde, Matthias K Weng, Kesavan Meganathan, Margit Henry, Agapios Sachinidis, Michael R Berthold,[...]. Arch Toxicol 2014
Nina V Balmer, Stefanie Klima, Eugen Rempel, Violeta N Ivanova, Raivo Kolde, Matthias K Weng, Kesavan Meganathan, Margit Henry, Agapios Sachinidis, Michael R Berthold,[...]. Arch Toxicol 2014
21
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors.
Eugen Rempel, Lisa Hoelting, Tanja Waldmann, Nina V Balmer, Stefan Schildknecht, Marianna Grinberg, John Antony Das Gaspar, Vaibhav Shinde, Regina Stöber, Rosemarie Marchan,[...]. Arch Toxicol 2015
Eugen Rempel, Lisa Hoelting, Tanja Waldmann, Nina V Balmer, Stefan Schildknecht, Marianna Grinberg, John Antony Das Gaspar, Vaibhav Shinde, Regina Stöber, Rosemarie Marchan,[...]. Arch Toxicol 2015
19
Expanding the test set: Chemicals with potential to disrupt mammalian brain development.
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
23
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.