William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
Times Cited: 551
Times Cited: 551
Times Cited
Times Co-cited
Similarity
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
40
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
30
TET-mediated active DNA demethylation: mechanism, function and beyond.
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
30
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
22
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
16
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
16
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
15
14
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6.
Qian Zhang, Kai Zhao, Qicong Shen, Yanmei Han, Yan Gu, Xia Li, Dezhi Zhao, Yiqi Liu, Chunmei Wang, Xiang Zhang,[...]. Nature 2015
Qian Zhang, Kai Zhao, Qicong Shen, Yanmei Han, Yan Gu, Xia Li, Dezhi Zhao, Yiqi Liu, Chunmei Wang, Xiang Zhang,[...]. Nature 2015
14
Role of TET enzymes in DNA methylation, development, and cancer.
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
13
Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility.
Chan-Wang Lio, Jiayuan Zhang, Edahí González-Avalos, Patrick G Hogan, Xing Chang, Anjana Rao. Elife 2016
Chan-Wang Lio, Jiayuan Zhang, Edahí González-Avalos, Patrick G Hogan, Xing Chang, Anjana Rao. Elife 2016
15
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Luisa Cimmino, Igor Dolgalev, Yubao Wang, Akihide Yoshimi, Gaëlle H Martin, Jingjing Wang, Victor Ng, Bo Xia, Matthew T Witkowski, Marisa Mitchell-Flack,[...]. Cell 2017
Luisa Cimmino, Igor Dolgalev, Yubao Wang, Akihide Yoshimi, Gaëlle H Martin, Jingjing Wang, Victor Ng, Bo Xia, Matthew T Witkowski, Marisa Mitchell-Flack,[...]. Cell 2017
13
Reversing DNA methylation: mechanisms, genomics, and biological functions.
Hao Wu, Yi Zhang. Cell 2014
Hao Wu, Yi Zhang. Cell 2014
13
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.
Kathryn Blaschke, Kevin T Ebata, Mohammad M Karimi, Jorge A Zepeda-Martínez, Preeti Goyal, Sahasransu Mahapatra, Angela Tam, Diana J Laird, Martin Hirst, Anjana Rao,[...]. Nature 2013
Kathryn Blaschke, Kevin T Ebata, Mohammad M Karimi, Jorge A Zepeda-Martínez, Preeti Goyal, Sahasransu Mahapatra, Angela Tam, Diana J Laird, Martin Hirst, Anjana Rao,[...]. Nature 2013
12
Control of Foxp3 stability through modulation of TET activity.
Xiaojing Yue, Sara Trifari, Tarmo Äijö, Ageliki Tsagaratou, William A Pastor, Jorge A Zepeda-Martínez, Chan-Wang J Lio, Xiang Li, Yun Huang, Pandurangan Vijayanand,[...]. J Exp Med 2016
Xiaojing Yue, Sara Trifari, Tarmo Äijö, Ageliki Tsagaratou, William A Pastor, Jorge A Zepeda-Martínez, Chan-Wang J Lio, Xiang Li, Yun Huang, Pandurangan Vijayanand,[...]. J Exp Med 2016
12
Mutation in TET2 in myeloid cancers.
François Delhommeau, Sabrina Dupont, Véronique Della Valle, Chloé James, Severine Trannoy, Aline Massé, Olivier Kosmider, Jean-Pierre Le Couedic, Fabienne Robert, Antonio Alberdi,[...]. N Engl J Med 2009
François Delhommeau, Sabrina Dupont, Véronique Della Valle, Chloé James, Severine Trannoy, Aline Massé, Olivier Kosmider, Jean-Pierre Le Couedic, Fabienne Robert, Antonio Alberdi,[...]. N Engl J Med 2009
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The DNA methyltransferase family: a versatile toolkit for epigenetic regulation.
Frank Lyko. Nat Rev Genet 2018
Frank Lyko. Nat Rev Genet 2018
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The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells.
Kenji Ichiyama, Tingting Chen, Xiaohu Wang, Xiaowei Yan, Byung-Seok Kim, Shinya Tanaka, Delphine Ndiaye-Lobry, Yuhua Deng, Yanli Zou, Pan Zheng,[...]. Immunity 2015
Kenji Ichiyama, Tingting Chen, Xiaohu Wang, Xiaowei Yan, Byung-Seok Kim, Shinya Tanaka, Delphine Ndiaye-Lobry, Yuhua Deng, Yanli Zou, Pan Zheng,[...]. Immunity 2015
11
Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis.
Ruili Yang, Cunye Qu, Yu Zhou, Joanne E Konkel, Shihong Shi, Yi Liu, Chider Chen, Shiyu Liu, Dawei Liu, Yibu Chen,[...]. Immunity 2015
Ruili Yang, Cunye Qu, Yu Zhou, Joanne E Konkel, Shihong Shi, Yi Liu, Chider Chen, Shiyu Liu, Dawei Liu, Yibu Chen,[...]. Immunity 2015
11
TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells.
Ageliki Tsagaratou, Edahí González-Avalos, Sini Rautio, James P Scott-Browne, Susan Togher, William A Pastor, Ellen V Rothenberg, Lukas Chavez, Harri Lähdesmäki, Anjana Rao. Nat Immunol 2017
Ageliki Tsagaratou, Edahí González-Avalos, Sini Rautio, James P Scott-Browne, Susan Togher, William A Pastor, Ellen V Rothenberg, Lukas Chavez, Harri Lähdesmäki, Anjana Rao. Nat Immunol 2017
14
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
11
DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
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Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice.
José J Fuster, Susan MacLauchlan, María A Zuriaga, Maya N Polackal, Allison C Ostriker, Raja Chakraborty, Chia-Ling Wu, Soichi Sano, Sujatha Muralidharan, Cristina Rius,[...]. Science 2017
José J Fuster, Susan MacLauchlan, María A Zuriaga, Maya N Polackal, Allison C Ostriker, Raja Chakraborty, Chia-Ling Wu, Soichi Sano, Sujatha Muralidharan, Cristina Rius,[...]. Science 2017
11
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.
Lulu Hu, Ze Li, Jingdong Cheng, Qinhui Rao, Wei Gong, Mengjie Liu, Yujiang Geno Shi, Jiayu Zhu, Ping Wang, Yanhui Xu. Cell 2013
Lulu Hu, Ze Li, Jingdong Cheng, Qinhui Rao, Wei Gong, Mengjie Liu, Yujiang Geno Shi, Jiayu Zhu, Ping Wang, Yanhui Xu. Cell 2013
10
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.
Yufei Xu, Feizhen Wu, Li Tan, Lingchun Kong, Lijun Xiong, Jie Deng, Andrew J Barbera, Lijuan Zheng, Haikuo Zhang, Stephen Huang,[...]. Mol Cell 2011
Yufei Xu, Feizhen Wu, Li Tan, Lingchun Kong, Lijun Xiong, Jie Deng, Andrew J Barbera, Lijuan Zheng, Haikuo Zhang, Stephen Huang,[...]. Mol Cell 2011
10
Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming.
Xiao Hu, Lei Zhang, Shi-Qing Mao, Zheng Li, Jiekai Chen, Run-Rui Zhang, Hai-Ping Wu, Juan Gao, Fan Guo, Wei Liu,[...]. Cell Stem Cell 2014
Xiao Hu, Lei Zhang, Shi-Qing Mao, Zheng Li, Jiekai Chen, Run-Rui Zhang, Hai-Ping Wu, Juan Gao, Fan Guo, Wei Liu,[...]. Cell Stem Cell 2014
10
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
10
TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the Aicda superenhancer.
Chan-Wang J Lio, Vipul Shukla, Daniela Samaniego-Castruita, Edahi González-Avalos, Abhijit Chakraborty, Xiaojing Yue, David G Schatz, Ferhat Ay, Anjana Rao. Sci Immunol 2019
Chan-Wang J Lio, Vipul Shukla, Daniela Samaniego-Castruita, Edahi González-Avalos, Abhijit Chakraborty, Xiaojing Yue, David G Schatz, Ferhat Ay, Anjana Rao. Sci Immunol 2019
28
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Kian Peng Koh, Akiko Yabuuchi, Sridhar Rao, Yun Huang, Kerrianne Cunniff, Julie Nardone, Asta Laiho, Mamta Tahiliani, Cesar A Sommer, Gustavo Mostoslavsky,[...]. Cell Stem Cell 2011
Kian Peng Koh, Akiko Yabuuchi, Sridhar Rao, Yun Huang, Kerrianne Cunniff, Julie Nardone, Asta Laiho, Mamta Tahiliani, Cesar A Sommer, Gustavo Mostoslavsky,[...]. Cell Stem Cell 2011
10
Functions of DNA methylation: islands, start sites, gene bodies and beyond.
Peter A Jones. Nat Rev Genet 2012
Peter A Jones. Nat Rev Genet 2012
10
The diverse roles of DNA methylation in mammalian development and disease.
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
10
TET proteins and 5-methylcytosine oxidation in hematological cancers.
Myunggon Ko, Jungeun An, William A Pastor, Sergei B Koralov, Klaus Rajewsky, Anjana Rao. Immunol Rev 2015
Myunggon Ko, Jungeun An, William A Pastor, Sergei B Koralov, Klaus Rajewsky, Anjana Rao. Immunol Rev 2015
9
TET Enzymes and 5hmC in Adaptive and Innate Immune Systems.
Chan-Wang J Lio, Anjana Rao. Front Immunol 2019
Chan-Wang J Lio, Anjana Rao. Front Immunol 2019
15
Loss of TET2 and TET3 in regulatory T cells unleashes effector function.
Xiaojing Yue, Chan-Wang J Lio, Daniela Samaniego-Castruita, Xiang Li, Anjana Rao. Nat Commun 2019
Xiaojing Yue, Chan-Wang J Lio, Daniela Samaniego-Castruita, Xiang Li, Anjana Rao. Nat Commun 2019
15
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
M Okano, D W Bell, D A Haber, E Li. Cell 1999
M Okano, D W Bell, D A Haber, E Li. Cell 1999
9
Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.
Meelad M Dawlaty, Achim Breiling, Thuc Le, M Inmaculada Barrasa, Günter Raddatz, Qing Gao, Benjamin E Powell, Albert W Cheng, Kym F Faull, Frank Lyko,[...]. Dev Cell 2014
Meelad M Dawlaty, Achim Breiling, Thuc Le, M Inmaculada Barrasa, Günter Raddatz, Qing Gao, Benjamin E Powell, Albert W Cheng, Kym F Faull, Frank Lyko,[...]. Dev Cell 2014
9
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids.
Lakshminarayan M Iyer, Mamta Tahiliani, Anjana Rao, L Aravind. Cell Cycle 2009
Lakshminarayan M Iyer, Mamta Tahiliani, Anjana Rao, L Aravind. Cell Cycle 2009
8
Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation.
Ageliki Tsagaratou, Tarmo Äijö, Chan-Wang J Lio, Xiaojing Yue, Yun Huang, Steven E Jacobsen, Harri Lähdesmäki, Anjana Rao. Proc Natl Acad Sci U S A 2014
Ageliki Tsagaratou, Tarmo Äijö, Chan-Wang J Lio, Xiaojing Yue, Yun Huang, Steven E Jacobsen, Harri Lähdesmäki, Anjana Rao. Proc Natl Acad Sci U S A 2014
8
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
8
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice.
Myunggon Ko, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Elizabeth C Thompson, Ryan Hastie, Angeliki Tsangaratou, Klaus Rajewsky, Sergei B Koralov, Anjana Rao. Proc Natl Acad Sci U S A 2011
Myunggon Ko, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Elizabeth C Thompson, Ryan Hastie, Angeliki Tsangaratou, Klaus Rajewsky, Sergei B Koralov, Anjana Rao. Proc Natl Acad Sci U S A 2011
8
Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.
Pietro Vella, Andrea Scelfo, Sriganesh Jammula, Fulvio Chiacchiera, Kristine Williams, Alessandro Cuomo, Alessandra Roberto, Jesper Christensen, Tiziana Bonaldi, Kristian Helin,[...]. Mol Cell 2013
Pietro Vella, Andrea Scelfo, Sriganesh Jammula, Fulvio Chiacchiera, Kristine Williams, Alessandro Cuomo, Alessandra Roberto, Jesper Christensen, Tiziana Bonaldi, Kristian Helin,[...]. Mol Cell 2013
8
WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.
Yiping Wang, Mengtao Xiao, Xiufei Chen, Leilei Chen, Yanping Xu, Lei Lv, Pu Wang, Hui Yang, Shenghong Ma, Huaipeng Lin,[...]. Mol Cell 2015
Yiping Wang, Mengtao Xiao, Xiufei Chen, Leilei Chen, Yanping Xu, Lei Lv, Pu Wang, Hui Yang, Shenghong Ma, Huaipeng Lin,[...]. Mol Cell 2015
8
TET2 promotes histone O-GlcNAcylation during gene transcription.
Qiang Chen, Yibin Chen, Chunjing Bian, Ryoji Fujiki, Xiaochun Yu. Nature 2013
Qiang Chen, Yibin Chen, Chunjing Bian, Ryoji Fujiki, Xiaochun Yu. Nature 2013
8
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.
Hao Wu, Ana C D'Alessio, Shinsuke Ito, Kai Xia, Zhibin Wang, Kairong Cui, Keji Zhao, Yi Eve Sun, Yi Zhang. Nature 2011
Hao Wu, Ana C D'Alessio, Shinsuke Ito, Kai Xia, Zhibin Wang, Kairong Cui, Keji Zhao, Yi Eve Sun, Yi Zhang. Nature 2011
8
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.
Meelad M Dawlaty, Kibibi Ganz, Benjamin E Powell, Yueh-Chiang Hu, Styliani Markoulaki, Albert W Cheng, Qing Gao, Jongpil Kim, Sang-Woon Choi, David C Page,[...]. Cell Stem Cell 2011
Meelad M Dawlaty, Kibibi Ganz, Benjamin E Powell, Yueh-Chiang Hu, Styliani Markoulaki, Albert W Cheng, Qing Gao, Jongpil Kim, Sang-Woon Choi, David C Page,[...]. Cell Stem Cell 2011
8
Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.
Ruichuan Yin, Shi-Qing Mao, Bailin Zhao, Zechen Chong, Ying Yang, Chao Zhao, Dapeng Zhang, Hua Huang, Juan Gao, Zheng Li,[...]. J Am Chem Soc 2013
Ruichuan Yin, Shi-Qing Mao, Bailin Zhao, Zechen Chong, Ying Yang, Chao Zhao, Dapeng Zhang, Hua Huang, Juan Gao, Zheng Li,[...]. J Am Chem Soc 2013
7
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian,[...]. Nat Biotechnol 2011
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian,[...]. Nat Biotechnol 2011
7
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
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Global epigenomic reconfiguration during mammalian brain development.
Ryan Lister, Eran A Mukamel, Joseph R Nery, Mark Urich, Clare A Puddifoot, Nicholas D Johnson, Jacinta Lucero, Yun Huang, Andrew J Dwork, Matthew D Schultz,[...]. Science 2013
Ryan Lister, Eran A Mukamel, Joseph R Nery, Mark Urich, Clare A Puddifoot, Nicholas D Johnson, Jacinta Lucero, Yun Huang, Andrew J Dwork, Matthew D Schultz,[...]. Science 2013
7
Model-based analysis of ChIP-Seq (MACS).
Yong Zhang, Tao Liu, Clifford A Meyer, Jérôme Eeckhoute, David S Johnson, Bradley E Bernstein, Chad Nusbaum, Richard M Myers, Myles Brown, Wei Li,[...]. Genome Biol 2008
Yong Zhang, Tao Liu, Clifford A Meyer, Jérôme Eeckhoute, David S Johnson, Bradley E Bernstein, Chad Nusbaum, Richard M Myers, Myles Brown, Wei Li,[...]. Genome Biol 2008
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.