A citation-based method for searching scientific literature

Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
Times Cited: 553







List of co-cited articles
1016 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
72


Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
542
42

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
799
42

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
38


STING is a direct innate immune sensor of cyclic di-GMP.
Dara L Burdette, Kathryn M Monroe, Katia Sotelo-Troha, Jeff S Iwig, Barbara Eckert, Mamoru Hyodo, Yoshihiro Hayakawa, Russell E Vance. Nature 2011
897
30

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Guijun Shang, Conggang Zhang, Zhijian J Chen, Xiao-Chen Bai, Xuewu Zhang. Nature 2019
183
30

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Qi Chen, Lijun Sun, Zhijian J Chen. Nat Immunol 2016
822
30

Structural basis of STING binding with and phosphorylation by TBK1.
Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature 2019
228
29

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.
Elie J Diner, Dara L Burdette, Stephen C Wilson, Kathryn M Monroe, Colleen A Kellenberger, Mamoru Hyodo, Yoshihiro Hayakawa, Ming C Hammond, Russell E Vance. Cell Rep 2013
441
28

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du, Zhijian J Chen. Nature 2019
328
28


Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.
Pu Gao, Manuel Ascano, Thomas Zillinger, Weiyi Wang, Peihong Dai, Artem A Serganov, Barbara L Gaffney, Stewart Shuman, Roger A Jones, Liang Deng,[...]. Cell 2013
301
26

Structural mechanism of cytosolic DNA sensing by cGAS.
Filiz Civril, Tobias Deimling, Carina C de Oliveira Mann, Andrea Ablasser, Manuela Moldt, Gregor Witte, Veit Hornung, Karl-Peter Hopfner. Nature 2013
393
26

Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.
Lingyin Li, Qian Yin, Pia Kuss, Zoltan Maliga, José L Millán, Hao Wu, Timothy J Mitchison. Nat Chem Biol 2014
202
26

Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
Xin Li, Chang Shu, Guanghui Yi, Catherine T Chaton, Catherine L Shelton, Jiasheng Diao, Xiaobing Zuo, C Cheng Kao, Andrew B Herr, Pingwei Li. Immunity 2013
295
26

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
636
26

Activated STING in a vascular and pulmonary syndrome.
Y Liu, A A Jesus, B Marrero, D Yang, S E Ramsey, G A Montealegre Sanchez, K Tenbrock, H Wittkowski, O Y Jones, H S Kuehn,[...]. N Engl J Med 2014
697
21

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.
Leticia Corrales, Laura Hix Glickman, Sarah M McWhirter, David B Kanne, Kelsey E Sivick, George E Katibah, Seng-Ryong Woo, Edward Lemmens, Tamara Banda, Justin J Leong,[...]. Cell Rep 2015
658
21

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.
Siqi Liu, Xin Cai, Jiaxi Wu, Qian Cong, Xiang Chen, Tuo Li, Fenghe Du, Junyao Ren, You-Tong Wu, Nick V Grishin,[...]. Science 2015
790
21

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
Bo Zhong, Yan Yang, Shu Li, Yan-Yi Wang, Ying Li, Feici Diao, Caoqi Lei, Xiao He, Lu Zhang, Po Tien,[...]. Immunity 2008
911
20

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung,[...]. Nature 2017
204
20

Design of amidobenzimidazole STING receptor agonists with systemic activity.
Joshi M Ramanjulu, G Scott Pesiridis, Jingsong Yang, Nestor Concha, Robert Singhaus, Shu-Yun Zhang, Jean-Luc Tran, Patrick Moore, Stephanie Lehmann, H Christian Eberl,[...]. Nature 2018
242
19

Targeting STING with covalent small-molecule inhibitors.
Simone M Haag, Muhammet F Gulen, Luc Reymond, Antoine Gibelin, Laurence Abrami, Alexiane Decout, Michael Heymann, F Gisou van der Goot, Gerardo Turcatti, Rayk Behrendt,[...]. Nature 2018
279
19



STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition.
Sabrina L Ergun, Daniel Fernandez, Thomas M Weiss, Lingyin Li. Cell 2019
91
20

STING: infection, inflammation and cancer.
Glen N Barber. Nat Rev Immunol 2015
584
18

Activation of STING requires palmitoylation at the Golgi.
Kojiro Mukai, Hiroyasu Konno, Tatsuya Akiba, Takefumi Uemura, Satoshi Waguri, Toshihide Kobayashi, Glen N Barber, Hiroyuki Arai, Tomohiko Taguchi. Nat Commun 2016
224
18

Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding.
Songying Ouyang, Xianqiang Song, Yaya Wang, Heng Ru, Neil Shaw, Yan Jiang, Fengfeng Niu, Yanping Zhu, Weicheng Qiu, Kislay Parvatiyar,[...]. Immunity 2012
218
18

cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
677
18

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Selene Glück, Baptiste Guey, Muhammet Fatih Gulen, Katharina Wolter, Tae-Won Kang, Niklas Arndt Schmacke, Anne Bridgeman, Jan Rehwinkel, Lars Zender, Andrea Ablasser. Nat Cell Biol 2017
444
17

STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease.
Nicole Dobbs, Nikolay Burnaevskiy, Didi Chen, Vijay K Gonugunta, Neal M Alto, Nan Yan. Cell Host Microbe 2015
255
17

cGAS is essential for cellular senescence.
Hui Yang, Hanze Wang, Junyao Ren, Qi Chen, Zhijian J Chen. Proc Natl Acad Sci U S A 2017
420
17

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Daxing Gao, Tuo Li, Xiao-Dong Li, Xiang Chen, Quan-Zhen Li, Mary Wight-Carter, Zhijian J Chen. Proc Natl Acad Sci U S A 2015
339
17

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.
Daxing Gao, Jiaxi Wu, You-Tong Wu, Fenghe Du, Chukwuemika Aroh, Nan Yan, Lijun Sun, Zhijian J Chen. Science 2013
645
17

The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.
Xu Zhang, Jiaxi Wu, Fenghe Du, Hui Xu, Lijun Sun, Zhe Chen, Chad A Brautigam, Xuewu Zhang, Zhijian J Chen. Cell Rep 2014
231
17

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
283
17

SLC19A1 transports immunoreactive cyclic dinucleotides.
Rutger D Luteijn, Shivam A Zaver, Benjamin G Gowen, Stacia K Wyman, Nick E Garelis, Liberty Onia, Sarah M McWhirter, George E Katibah, Jacob E Corn, Joshua J Woodward,[...]. Nature 2019
119
16

Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
507
16

Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.
Chang Shu, Guanghui Yi, Tylan Watts, C Cheng Kao, Pingwei Li. Nat Struct Mol Biol 2012
178
16

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
Olivier Demaria, Aude De Gassart, Sanja Coso, Nicolas Gestermann, Jeremy Di Domizio, Lukas Flatz, Olivier Gaide, Olivier Michielin, Patrick Hwu, Tatiana V Petrova,[...]. Proc Natl Acad Sci U S A 2015
257
15

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization.
Wenxiang Sun, Yang Li, Lu Chen, Huihui Chen, Fuping You, Xiang Zhou, Yi Zhou, Zhonghe Zhai, Danying Chen, Zhengfan Jiang. Proc Natl Acad Sci U S A 2009
490
15

Cyclic di-GMP sensing via the innate immune signaling protein STING.
Qian Yin, Yuan Tian, Venkataraman Kabaleeswaran, Xiaomo Jiang, Daqi Tu, Michael J Eck, Zhijian J Chen, Hao Wu. Mol Cell 2012
164
15

Structural basis of nucleosome-dependent cGAS inhibition.
Joshua A Boyer, Cathy J Spangler, Joshua D Strauss, Andrew P Cesmat, Pengda Liu, Robert K McGinty, Qi Zhang. Science 2020
75
20

Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance.
Wen Zhou, Aaron T Whiteley, Carina C de Oliveira Mann, Benjamin R Morehouse, Radosław P Nowak, Eric S Fischer, Nathanael S Gray, John J Mekalanos, Philip J Kranzusch. Cell 2018
127
15

Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity.
Philip J Kranzusch, Amy Si-Ying Lee, James M Berger, Jennifer A Doudna. Cell Rep 2013
214
15

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.
Katherine C Barnett, Julia M Coronas-Serna, Wen Zhou, Michael J Ernandes, Anh Cao, Philip J Kranzusch, Jonathan C Kagan. Cell 2019
97
15

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling.
Xin Cai, Yu-Hsin Chiu, Zhijian J Chen. Mol Cell 2014
532
15


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.