Luke A Gilbert, Matthew H Larson, Leonardo Morsut, Zairan Liu, Gloria A Brar, Sandra E Torres, Noam Stern-Ginossar, Onn Brandman, Evan H Whitehead, Jennifer A Doudna, Wendell A Lim, Jonathan S Weissman, Lei S Qi. Cell 2013
Times Cited: 1930
Times Cited: 1930
Times Cited
Times Co-cited
Similarity
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
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A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Highly efficient Cas9-mediated transcriptional programming.
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Alejandro Chavez, Jonathan Scheiman, Suhani Vora, Benjamin W Pruitt, Marcelle Tuttle, Eswar P R Iyer, Shuailiang Lin, Samira Kiani, Christopher D Guzman, Daniel J Wiegand,[...]. Nat Methods 2015
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Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
Luke A Gilbert, Max A Horlbeck, Britt Adamson, Jacqueline E Villalta, Yuwen Chen, Evan H Whitehead, Carla Guimaraes, Barbara Panning, Hidde L Ploegh, Michael C Bassik,[...]. Cell 2014
Luke A Gilbert, Max A Horlbeck, Britt Adamson, Jacqueline E Villalta, Yuwen Chen, Evan H Whitehead, Carla Guimaraes, Barbara Panning, Hidde L Ploegh, Michael C Bassik,[...]. Cell 2014
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.
Isaac B Hilton, Anthony M D'Ippolito, Christopher M Vockley, Pratiksha I Thakore, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach. Nat Biotechnol 2015
Isaac B Hilton, Anthony M D'Ippolito, Christopher M Vockley, Pratiksha I Thakore, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach. Nat Biotechnol 2015
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
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In vivo genome editing using Staphylococcus aureus Cas9.
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Search-and-replace genome editing without double-strand breaks or donor DNA.
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
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CRISPR RNA-guided activation of endogenous human genes.
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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
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Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
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A protein-tagging system for signal amplification in gene expression and fluorescence imaging.
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RNA-guided gene activation by CRISPR-Cas9-based transcription factors.
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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
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RNA editing with CRISPR-Cas13.
David B T Cox, Jonathan S Gootenberg, Omar O Abudayyeh, Brian Franklin, Max J Kellner, Julia Joung, Feng Zhang. Science 2017
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RNA targeting with CRISPR-Cas13.
Omar O Abudayyeh, Jonathan S Gootenberg, Patrick Essletzbichler, Shuo Han, Julia Joung, Joseph J Belanto, Vanessa Verdine, David B T Cox, Max J Kellner, Aviv Regev,[...]. Nature 2017
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Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
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Genome-scale CRISPR-Cas9 knockout screening in human cells.
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DNA targeting specificity of RNA-guided Cas9 nucleases.
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CRISPR provides acquired resistance against viruses in prokaryotes.
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Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.
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Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
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CRISPR-Cas systems for editing, regulating and targeting genomes.
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Crystal structure of Cas9 in complex with guide RNA and target DNA.
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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.
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Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
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Functional annotation of native enhancers with a Cas9-histone demethylase fusion.
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Nicola A Kearns, Hannah Pham, Barbara Tabak, Ryan M Genga, Noah J Silverstein, Manuel Garber, René Maehr. Nat Methods 2015
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Development and applications of CRISPR-Cas9 for genome engineering.
Patrick D Hsu, Eric S Lander, Feng Zhang. Cell 2014
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Editing DNA Methylation in the Mammalian Genome.
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11
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
Pratiksha I Thakore, Anthony M D'Ippolito, Lingyun Song, Alexias Safi, Nishkala K Shivakumar, Ami M Kabadi, Timothy E Reddy, Gregory E Crawford, Charles A Gersbach. Nat Methods 2015
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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
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Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements.
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In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni.
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Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
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Genetic screens in human cells using the CRISPR-Cas9 system.
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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.
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Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.
Silvana Konermann, Peter Lotfy, Nicholas J Brideau, Jennifer Oki, Maxim N Shokhirev, Patrick D Hsu. Cell 2018
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
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Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
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An enhanced CRISPR repressor for targeted mammalian gene regulation.
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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
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Genome engineering using the CRISPR-Cas9 system.
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Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.
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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.