A Persson, S C Sim, S Virding, N Onishchenko, G Schulte, M Ingelman-Sundberg. Mol Psychiatry 2014
Times Cited: 37
Times Cited: 37
Times Cited
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J C Stingl, J Brockmöller, R Viviani. Mol Psychiatry 2013
35
Association between CYP2C19 polymorphism and depressive symptoms.
Sarah C Sim, Linn Nordin, Therese M-L Andersson, Susanne Virding, Marita Olsson, Nancy L Pedersen, Magnus Ingelman-Sundberg. Am J Med Genet B Neuropsychiatr Genet 2010
Sarah C Sim, Linn Nordin, Therese M-L Andersson, Susanne Virding, Marita Olsson, Nancy L Pedersen, Magnus Ingelman-Sundberg. Am J Med Genet B Neuropsychiatr Genet 2010
36
Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function.
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Fabien Dutheil, Sandrine Dauchy, Monique Diry, Véronique Sazdovitch, Olivier Cloarec, Lucille Mellottée, Ivan Bièche, Magnus Ingelman-Sundberg, Jean-Pierre Flinois, Isabelle de Waziers,[...]. Drug Metab Dispos 2009
18
Genetic variation in CYP2D6 impacts neural activation during cognitive tasks in humans.
Julia C Stingl, Christine Esslinger, Heike Tost, Edda Bilek, Peter Kirsch, Barbara Ohmle, Roberto Viviani, Henrik Walter, Marcella Rietschel, Andreas Meyer-Lindenberg. Neuroimage 2012
Julia C Stingl, Christine Esslinger, Heike Tost, Edda Bilek, Peter Kirsch, Barbara Ohmle, Roberto Viviani, Henrik Walter, Marcella Rietschel, Andreas Meyer-Lindenberg. Neuroimage 2012
23
Cytochrome P450 mediates dopamine formation in the brain in vivo.
Ewa Bromek, Anna Haduch, Krystyna Gołembiowska, Władysława A Daniel. J Neurochem 2011
Ewa Bromek, Anna Haduch, Krystyna Gołembiowska, Władysława A Daniel. J Neurochem 2011
16
Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment.
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M M Jukić, N Opel, J Ström, T Carrillo-Roa, S Miksys, M Novalen, A Renblom, S C Sim, E M Peñas-Lledó, P Courtet,[...]. Mol Psychiatry 2017
31
CYP2D6 in the brain: genotype effects on resting brain perfusion.
J Kirchheiner, A Seeringer, A L Godoy, B Ohmle, C Maier, P Beschoner, E-J Sim, R Viviani. Mol Psychiatry 2011
J Kirchheiner, A Seeringer, A L Godoy, B Ohmle, C Maier, P Beschoner, E-J Sim, R Viviani. Mol Psychiatry 2011
13
Cytochrome P450 enzymes in the brain: emerging evidence of biological significance.
Charmaine S Ferguson, Rachel F Tyndale. Trends Pharmacol Sci 2011
Charmaine S Ferguson, Rachel F Tyndale. Trends Pharmacol Sci 2011
13
Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects.
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Magnus Ingelman-Sundberg, Sarah C Sim, Alvin Gomez, Cristina Rodriguez-Antona. Pharmacol Ther 2007
13
Potential role of CYP2D6 in the central nervous system.
Jie Cheng, Yueying Zhen, Sharon Miksys, Diren Beyoğlu, Kristopher W Krausz, Rachel F Tyndale, Aiming Yu, Jeffrey R Idle, Frank J Gonzalez. Xenobiotica 2013
Jie Cheng, Yueying Zhen, Sharon Miksys, Diren Beyoğlu, Kristopher W Krausz, Rachel F Tyndale, Aiming Yu, Jeffrey R Idle, Frank J Gonzalez. Xenobiotica 2013
13
CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics-guided clinical trials.
Eva M Peñas-Lledó, Adrián Llerena. Br J Clin Pharmacol 2014
Eva M Peñas-Lledó, Adrián Llerena. Br J Clin Pharmacol 2014
16
High frequency of occurrence of CYP2D6 gene duplication/multiduplication indicating ultrarapid metabolism among suicide cases.
A L Zackrisson, B Lindblom, J Ahlner. Clin Pharmacol Ther 2010
A L Zackrisson, B Lindblom, J Ahlner. Clin Pharmacol Ther 2010
13
Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics.
Sharon Miksys, Yushu Rao, Ewa Hoffmann, Deborah C Mash, Rachel F Tyndale. J Neurochem 2002
Sharon Miksys, Yushu Rao, Ewa Hoffmann, Deborah C Mash, Rachel F Tyndale. J Neurochem 2002
13
Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment.
Amandeep Mann, Sharon Miksys, Anna Lee, Deborah C Mash, Rachel F Tyndale. Neuropharmacology 2008
Amandeep Mann, Sharon Miksys, Anna Lee, Deborah C Mash, Rachel F Tyndale. Neuropharmacology 2008
13
Cytochrome P450-mediated drug metabolism in the brain.
Sharon Miksys, Rachel F Tyndale. J Psychiatry Neurosci 2013
Sharon Miksys, Rachel F Tyndale. J Psychiatry Neurosci 2013
13
Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6.
Ai-Ming Yu, Jeffrey R Idle, Linda G Byrd, Kristopher W Krausz, Adrian Küpfer, Frank J Gonzalez. Pharmacogenetics 2003
Ai-Ming Yu, Jeffrey R Idle, Linda G Byrd, Kristopher W Krausz, Adrian Küpfer, Frank J Gonzalez. Pharmacogenetics 2003
10
Dopamine formation from tyramine by CYP2D6.
T Hiroi, S Imaoka, Y Funae. Biochem Biophys Res Commun 1998
T Hiroi, S Imaoka, Y Funae. Biochem Biophys Res Commun 1998
10
Drug-metabolizing cytochrome P450s in the brain.
Sharon L Miksys, Rachel F Tyndale. J Psychiatry Neurosci 2002
Sharon L Miksys, Rachel F Tyndale. J Psychiatry Neurosci 2002
10
The unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics.
Sharon Miksys, Rachel F Tyndale. Drug Metab Rev 2004
Sharon Miksys, Rachel F Tyndale. Drug Metab Rev 2004
10
The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6.
Natasha T Snider, Matthew J Sikora, Chitra Sridar, Thomas J Feuerstein, James M Rae, Paul F Hollenberg. J Pharmacol Exp Ther 2008
Natasha T Snider, Matthew J Sikora, Chitra Sridar, Thomas J Feuerstein, James M Rae, Paul F Hollenberg. J Pharmacol Exp Ther 2008
10
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity.
M Ingelman-Sundberg. Pharmacogenomics J 2005
M Ingelman-Sundberg. Pharmacogenomics J 2005
10
Debrisoquine hydroxylation polymorphism and personality.
L Bertilsson, C Alm, C De Las Carreras, J Widen, G Edman, D Schalling. Lancet 1989
L Bertilsson, C Alm, C De Las Carreras, J Widen, G Edman, D Schalling. Lancet 1989
10
Cytochrome P-450 activities in human and rat brain microsomes.
P Voirol, M Jonzier-Perey, F Porchet, M J Reymond, R C Janzer, C Bouras, H W Strobel, M Kosel, C B Eap, P Baumann. Brain Res 2000
P Voirol, M Jonzier-Perey, F Porchet, M J Reymond, R C Janzer, C Bouras, H W Strobel, M Kosel, C B Eap, P Baumann. Brain Res 2000
10
Cytochrome P4502D4 in the brain: specific neuronal regulation by clozapine and toluene.
E Hedlund, A Wyss, T Kainu, M Backlund, C Köhler, M Pelto-Huikko, J A Gustafsson, M Warner. Mol Pharmacol 1996
E Hedlund, A Wyss, T Kainu, M Backlund, C Köhler, M Pelto-Huikko, J A Gustafsson, M Warner. Mol Pharmacol 1996
10
Regional and cellular distribution of CYP2D subfamily members in rat brain.
S Miksys, Y Rao, E M Sellers, M Kwan, D Mendis, R F Tyndale. Xenobiotica 2000
S Miksys, Y Rao, E M Sellers, M Kwan, D Mendis, R F Tyndale. Xenobiotica 2000
10
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.
Sarah C Sim, Carl Risinger, Marja-Liisa Dahl, Eleni Aklillu, Magnus Christensen, Leif Bertilsson, Magnus Ingelman-Sundberg. Clin Pharmacol Ther 2006
Sarah C Sim, Carl Risinger, Marja-Liisa Dahl, Eleni Aklillu, Magnus Christensen, Leif Bertilsson, Magnus Ingelman-Sundberg. Clin Pharmacol Ther 2006
10
Polymorphic expression of CYP2C19 and CYP2D6 in the developing and adult human brain causing variability in cognition, risk for depression and suicide: the search for the endogenous substrates.
Magnus Ingelman-Sundberg, Anna Persson, Marin M Jukic. Pharmacogenomics 2014
Magnus Ingelman-Sundberg, Anna Persson, Marin M Jukic. Pharmacogenomics 2014
25
Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells.
Amandeep Mann, Rachel F Tyndale. Eur J Neurosci 2010
Amandeep Mann, Rachel F Tyndale. Eur J Neurosci 2010
8
Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response.
J Kirchheiner, K Nickchen, M Bauer, M-L Wong, J Licinio, I Roots, J Brockmöller. Mol Psychiatry 2004
J Kirchheiner, K Nickchen, M Bauer, M-L Wong, J Licinio, I Roots, J Brockmöller. Mol Psychiatry 2004
8
High risk of lifetime history of suicide attempts among CYP2D6 ultrarapid metabolizers with eating disorders.
E M Peñas-Lledó, P Dorado, Z Agüera, M Gratacós, X Estivill, F Fernández-Aranda, A Llerena. Mol Psychiatry 2011
E M Peñas-Lledó, P Dorado, Z Agüera, M Gratacós, X Estivill, F Fernández-Aranda, A Llerena. Mol Psychiatry 2011
8
CYP2C19 variation and citalopram response.
David A Mrazek, Joanna M Biernacka, Dennis J O'Kane, John L Black, Julie M Cunningham, Maureen S Drews, Karen A Snyder, Susanna R Stevens, Augustus John Rush, Richard M Weinshilboum. Pharmacogenet Genomics 2011
David A Mrazek, Joanna M Biernacka, Dennis J O'Kane, John L Black, Julie M Cunningham, Maureen S Drews, Karen A Snyder, Susanna R Stevens, Augustus John Rush, Richard M Weinshilboum. Pharmacogenet Genomics 2011
8
Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response.
Ming-Hsien Tsai, Keh-Ming Lin, Mei-Chun Hsiao, Winston W Shen, Mong-Liang Lu, Hwa-Sheng Tang, Chun-Kai Fang, Chi-Shin Wu, Shao-Chun Lu, Shu Chih Liu,[...]. Pharmacogenomics 2010
Ming-Hsien Tsai, Keh-Ming Lin, Mei-Chun Hsiao, Winston W Shen, Mong-Liang Lu, Hwa-Sheng Tang, Chun-Kai Fang, Chi-Shin Wu, Shao-Chun Lu, Shu Chih Liu,[...]. Pharmacogenomics 2010
8
Impact of the ultrarapid CYP2C19*17 allele on serum concentration of escitalopram in psychiatric patients.
I Rudberg, B Mohebi, M Hermann, H Refsum, E Molden. Clin Pharmacol Ther 2008
I Rudberg, B Mohebi, M Hermann, H Refsum, E Molden. Clin Pharmacol Ther 2008
8
CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study.
Thomas Rau, Gerlinde Wohlleben, Henrike Wuttke, Norbert Thuerauf, Jens Lunkenheimer, Mario Lanczik, Thomas Eschenhagen. Clin Pharmacol Ther 2004
Thomas Rau, Gerlinde Wohlleben, Henrike Wuttke, Norbert Thuerauf, Jens Lunkenheimer, Mario Lanczik, Thomas Eschenhagen. Clin Pharmacol Ther 2004
8
Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain.
Shankar J Chinta, Harish V Pai, Sudarshan C Upadhya, Michael R Boyd, Vijayalakshmi Ravindranath. Brain Res Mol Brain Res 2002
Shankar J Chinta, Harish V Pai, Sudarshan C Upadhya, Michael R Boyd, Vijayalakshmi Ravindranath. Brain Res Mol Brain Res 2002
8
Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain.
I Siegle, P Fritz, K Eckhardt, U M Zanger, M Eichelbaum. Pharmacogenetics 2001
I Siegle, P Fritz, K Eckhardt, U M Zanger, M Eichelbaum. Pharmacogenetics 2001
8
Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6.
A Llerena, G Edman, J Cobaleda, J Benítez, D Schalling, L Bertilsson. Acta Psychiatr Scand 1993
A Llerena, G Edman, J Cobaleda, J Benítez, D Schalling, L Bertilsson. Acta Psychiatr Scand 1993
8
Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.
Rongrong Jiang, Satoshi Yamaori, Shuso Takeda, Ikuo Yamamoto, Kazuhito Watanabe. Life Sci 2011
Rongrong Jiang, Satoshi Yamaori, Shuso Takeda, Ikuo Yamamoto, Kazuhito Watanabe. Life Sci 2011
8
Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor.
Paul Berghuis, Marton B Dobszay, Xinyu Wang, Sabrina Spano, Fernanda Ledda, Kyle M Sousa, Gunnar Schulte, Patrik Ernfors, Ken Mackie, Gustavo Paratcha,[...]. Proc Natl Acad Sci U S A 2005
Paul Berghuis, Marton B Dobszay, Xinyu Wang, Sabrina Spano, Fernanda Ledda, Kyle M Sousa, Gunnar Schulte, Patrik Ernfors, Ken Mackie, Gustavo Paratcha,[...]. Proc Natl Acad Sci U S A 2005
8
Relation between CYP2D6 phenotype and genotype and personality in healthy volunteers.
Idilio González, Eva M Peñas-Lledó, Bárbaro Pérez, Pedro Dorado, Mayra Alvarez, Adrián LLerena. Pharmacogenomics 2008
Idilio González, Eva M Peñas-Lledó, Bárbaro Pérez, Pedro Dorado, Mayra Alvarez, Adrián LLerena. Pharmacogenomics 2008
8
The positive and negative syndrome scale (PANSS) for schizophrenia.
S R Kay, A Fiszbein, L A Opler. Schizophr Bull 1987
S R Kay, A Fiszbein, L A Opler. Schizophr Bull 1987
8
Nicotine Increases Codeine Analgesia Through the Induction of Brain CYP2D and Central Activation of Codeine to Morphine.
Douglas M McMillan, Rachel F Tyndale. Neuropsychopharmacology 2015
Douglas M McMillan, Rachel F Tyndale. Neuropsychopharmacology 2015
10
CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease.
Alexis Elbaz, Clotilde Levecque, Jacqueline Clavel, Jean-Sébastien Vidal, Florence Richard, Philippe Amouyel, Annick Alpérovitch, Marie-Christine Chartier-Harlin, Christophe Tzourio. Ann Neurol 2004
Alexis Elbaz, Clotilde Levecque, Jacqueline Clavel, Jean-Sébastien Vidal, Florence Richard, Philippe Amouyel, Annick Alpérovitch, Marie-Christine Chartier-Harlin, Christophe Tzourio. Ann Neurol 2004
8
Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys.
Charmaine S Ferguson, Sharon Miksys, Roberta M Palmour, Rachel F Tyndale. Neuropharmacology 2013
Charmaine S Ferguson, Sharon Miksys, Roberta M Palmour, Rachel F Tyndale. Neuropharmacology 2013
15
Anti-epileptic drug phenytoin enhances androgen metabolism and androgen receptor expression in murine hippocampus.
Ralf Peter Meyer, Christoph Eugen Hagemeyer, Rolf Knoth, Michel Rene Kaufmann, Benedikt Volk. J Neurochem 2006
Ralf Peter Meyer, Christoph Eugen Hagemeyer, Rolf Knoth, Michel Rene Kaufmann, Benedikt Volk. J Neurochem 2006
11
First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.
Kaidi Zhou, Jibran Y Khokhar, Bin Zhao, Rachel F Tyndale. Biochem Pharmacol 2013
Kaidi Zhou, Jibran Y Khokhar, Bin Zhao, Rachel F Tyndale. Biochem Pharmacol 2013
9
Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment.
S Miksys, E Hoffmann, R F Tyndale. Biochem Pharmacol 2000
S Miksys, E Hoffmann, R F Tyndale. Biochem Pharmacol 2000
8
Distribution of mRNAs encoding the arylhydrocarbon receptor, arylhydrocarbon receptor nuclear translocator, and arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem.
S L Petersen, M A Curran, S A Marconi, C D Carpenter, L S Lubbers, M D McAbee. J Comp Neurol 2000
S L Petersen, M A Curran, S A Marconi, C D Carpenter, L S Lubbers, M D McAbee. J Comp Neurol 2000
8
Drug metabolism within the brain changes drug response: selective manipulation of brain CYP2B alters propofol effects.
Jibran Y Khokhar, Rachel F Tyndale. Neuropsychopharmacology 2011
Jibran Y Khokhar, Rachel F Tyndale. Neuropsychopharmacology 2011
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.