Katrien De Bock, Maria Georgiadou, Sandra Schoors, Anna Kuchnio, Brian W Wong, Anna Rita Cantelmo, Annelies Quaegebeur, Bart Ghesquière, Sandra Cauwenberghs, Guy Eelen, Li-Kun Phng, Inge Betz, Bieke Tembuyser, Katleen Brepoels, Jonathan Welti, Ilse Geudens, Inmaculada Segura, Bert Cruys, Franscesco Bifari, Ilaria Decimo, Raquel Blanco, Sabine Wyns, Jeroen Vangindertael, Susana Rocha, Russel T Collins, Sebastian Munck, Dirk Daelemans, Hiromi Imamura, Roland Devlieger, Mark Rider, Paul P Van Veldhoven, Frans Schuit, Ramon Bartrons, Johan Hofkens, Peter Fraisl, Sucheta Telang, Ralph J Deberardinis, Luc Schoonjans, Stefan Vinckier, Jason Chesney, Holger Gerhardt, Mieke Dewerchin, Peter Carmeliet. Cell 2013
Times Cited: 722
Times Cited: 722
Times Cited
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Similarity
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.
Sandra Schoors, Katrien De Bock, Anna Rita Cantelmo, Maria Georgiadou, Bart Ghesquière, Sandra Cauwenberghs, Anna Kuchnio, Brian W Wong, Annelies Quaegebeur, Jermaine Goveia,[...]. Cell Metab 2014
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Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.
Anna Rita Cantelmo, Lena-Christin Conradi, Aleksandra Brajic, Jermaine Goveia, Joanna Kalucka, Andreas Pircher, Pallavi Chaturvedi, Johanna Hol, Bernard Thienpont, Laure-Anne Teuwen,[...]. Cancer Cell 2016
Anna Rita Cantelmo, Lena-Christin Conradi, Aleksandra Brajic, Jermaine Goveia, Joanna Kalucka, Andreas Pircher, Pallavi Chaturvedi, Johanna Hol, Bernard Thienpont, Laure-Anne Teuwen,[...]. Cancer Cell 2016
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Endothelial Cell Metabolism.
Guy Eelen, Pauline de Zeeuw, Lucas Treps, Ulrike Harjes, Brian W Wong, Peter Carmeliet. Physiol Rev 2018
Guy Eelen, Pauline de Zeeuw, Lucas Treps, Ulrike Harjes, Brian W Wong, Peter Carmeliet. Physiol Rev 2018
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Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Sandra Schoors, Ulrike Bruning, Rindert Missiaen, Karla Cs Queiroz, Gitte Borgers, Ilaria Elia, Annalisa Zecchin, Anna Rita Cantelmo, Stefan Christen, Jermaine Goveia,[...]. Nature 2015
Sandra Schoors, Ulrike Bruning, Rindert Missiaen, Karla Cs Queiroz, Gitte Borgers, Ilaria Elia, Annalisa Zecchin, Anna Rita Cantelmo, Stefan Christen, Jermaine Goveia,[...]. Nature 2015
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Role of endothelial cell metabolism in vessel sprouting.
Katrien De Bock, Maria Georgiadou, Peter Carmeliet. Cell Metab 2013
Katrien De Bock, Maria Georgiadou, Peter Carmeliet. Cell Metab 2013
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Endothelial PFKFB3 plays a critical role in angiogenesis.
Yiming Xu, Xiaofei An, Xin Guo, Tsadik Ghebreamlak Habtetsion, Yong Wang, Xizhen Xu, Sridhar Kandala, Qinkai Li, Honggui Li, Chunxiang Zhang,[...]. Arterioscler Thromb Vasc Biol 2014
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Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3.
Anuradha Doddaballapur, Katharina M Michalik, Yosif Manavski, Tina Lucas, Riekelt H Houtkooper, Xintian You, Wei Chen, Andreas M Zeiher, Michael Potente, Stefanie Dimmeler,[...]. Arterioscler Thromb Vasc Biol 2015
Anuradha Doddaballapur, Katharina M Michalik, Yosif Manavski, Tina Lucas, Riekelt H Houtkooper, Xintian You, Wei Chen, Andreas M Zeiher, Michael Potente, Stefanie Dimmeler,[...]. Arterioscler Thromb Vasc Biol 2015
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Glutamine fuels proliferation but not migration of endothelial cells.
Boa Kim, Jia Li, Cholsoon Jang, Zoltan Arany. EMBO J 2017
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Endothelial cell metabolism in normal and diseased vasculature.
Guy Eelen, Pauline de Zeeuw, Michael Simons, Peter Carmeliet. Circ Res 2015
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Basic and therapeutic aspects of angiogenesis.
Michael Potente, Holger Gerhardt, Peter Carmeliet. Cell 2011
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Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.
Joanna Kalucka, Laura Bierhansl, Nadine Vasconcelos Conchinha, Rindert Missiaen, Ilaria Elia, Ulrike Brüning, Samantha Scheinok, Lucas Treps, Anna Rita Cantelmo, Charlotte Dubois,[...]. Cell Metab 2018
Joanna Kalucka, Laura Bierhansl, Nadine Vasconcelos Conchinha, Rindert Missiaen, Ilaria Elia, Ulrike Brüning, Samantha Scheinok, Lucas Treps, Anna Rita Cantelmo, Charlotte Dubois,[...]. Cell Metab 2018
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Hallmarks of Endothelial Cell Metabolism in Health and Disease.
Xuri Li, Xiaodong Sun, Peter Carmeliet. Cell Metab 2019
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Single-Cell Transcriptome Atlas of Murine Endothelial Cells.
Joanna Kalucka, Laura P M H de Rooij, Jermaine Goveia, Katerina Rohlenova, Sébastien J Dumas, Elda Meta, Nadine V Conchinha, Federico Taverna, Laure-Anne Teuwen, Koen Veys,[...]. Cell 2020
Joanna Kalucka, Laura P M H de Rooij, Jermaine Goveia, Katerina Rohlenova, Sébastien J Dumas, Elda Meta, Nadine V Conchinha, Federico Taverna, Laure-Anne Teuwen, Koen Veys,[...]. Cell 2020
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PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension.
Yapeng Cao, Xiaoyu Zhang, Lina Wang, Qiuhua Yang, Qian Ma, Jiean Xu, Jingjing Wang, Laszlo Kovacs, Ramon J Ayon, Zhiping Liu,[...]. Proc Natl Acad Sci U S A 2019
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Role of glutamine and interlinked asparagine metabolism in vessel formation.
Hongling Huang, Saar Vandekeere, Joanna Kalucka, Laura Bierhansl, Annalisa Zecchin, Ulrike Brüning, Asjad Visnagri, Nadira Yuldasheva, Jermaine Goveia, Bert Cruys,[...]. EMBO J 2017
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HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium.
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Molecular mechanisms and clinical applications of angiogenesis.
Peter Carmeliet, Rakesh K Jain. Nature 2011
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FOXO1 couples metabolic activity and growth state in the vascular endothelium.
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Metabolism of exogenous substrates by coronary endothelial cells in culture.
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FGF-dependent metabolic control of vascular development.
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The role of fatty acid β-oxidation in lymphangiogenesis.
Brian W Wong, Xingwu Wang, Annalisa Zecchin, Bernard Thienpont, Ivo Cornelissen, Joanna Kalucka, Melissa García-Caballero, Rindert Missiaen, Hongling Huang, Ulrike Brüning,[...]. Nature 2017
Brian W Wong, Xingwu Wang, Annalisa Zecchin, Bernard Thienpont, Ivo Cornelissen, Joanna Kalucka, Melissa García-Caballero, Rindert Missiaen, Hongling Huang, Ulrike Brüning,[...]. Nature 2017
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Glycolytic regulation of cell rearrangement in angiogenesis.
Bert Cruys, Brian W Wong, Anna Kuchnio, Dries Verdegem, Anna Rita Cantelmo, Lena-Christin Conradi, Saar Vandekeere, Ann Bouché, Ivo Cornelissen, Stefan Vinckier,[...]. Nat Commun 2016
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Roles of PFKFB3 in cancer.
Linlin Shi, Hongming Pan, Zhen Liu, Jiansheng Xie, Weidong Han. Signal Transduct Target Ther 2017
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The Link Between Angiogenesis and Endothelial Metabolism.
Michael Potente, Peter Carmeliet. Annu Rev Physiol 2017
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Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer.
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Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites.
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Endothelial Cell Metabolism in Atherosclerosis.
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Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.
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Endothelial Cell Metabolism in Health and Disease.
Katerina Rohlenova, Koen Veys, Ines Miranda-Santos, Katrien De Bock, Peter Carmeliet. Trends Cell Biol 2018
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Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease.
Jermaine Goveia, Peter Stapor, Peter Carmeliet. EMBO Mol Med 2014
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Metabolic Pathways Fueling the Endothelial Cell Drive.
Xuri Li, Anil Kumar, Peter Carmeliet. Annu Rev Physiol 2019
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Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
Katerina Rohlenova, Jermaine Goveia, Melissa García-Caballero, Abhishek Subramanian, Joanna Kalucka, Lucas Treps, Kim D Falkenberg, Laura P M H de Rooij, Yingfeng Zheng, Lin Lin,[...]. Cell Metab 2020
Katerina Rohlenova, Jermaine Goveia, Melissa García-Caballero, Abhishek Subramanian, Joanna Kalucka, Lucas Treps, Kim D Falkenberg, Laura P M H de Rooij, Yingfeng Zheng, Lin Lin,[...]. Cell Metab 2020
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Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization.
Jing Zhang, Jonathan Muri, Gillian Fitzgerald, Tatiane Gorski, Roberto Gianni-Barrera, Evi Masschelein, Gommaar D'Hulst, Paola Gilardoni, Guillermo Turiel, Zheng Fan,[...]. Cell Metab 2020
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Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia.
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Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
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Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis.
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Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity.
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Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability.
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Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets.
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Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction.
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Michael Vanlandewijck, Liqun He, Maarja Andaloussi Mäe, Johanna Andrae, Koji Ando, Francesca Del Gaudio, Khayrun Nahar, Thibaud Lebouvier, Bàrbara Laviña, Leonor Gouveia,[...]. Nature 2018
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Endothelial pyruvate kinase M2 maintains vascular integrity.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.