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Times Cited: 910
Times Cited: 910
Times Cited
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Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor.
William J Zacharias, David B Frank, Jarod A Zepp, Michael P Morley, Farrah A Alkhaleel, Jun Kong, Su Zhou, Edward Cantu, Edward E Morrisey. Nature 2018
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Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis.
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Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells.
Ahmad N Nabhan, Douglas G Brownfield, Pehr B Harbury, Mark A Krasnow, Tushar J Desai. Science 2018
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Alveolar progenitor and stem cells in lung development, renewal and cancer.
Tushar J Desai, Douglas G Brownfield, Mark A Krasnow. Nature 2014
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Basal cells as stem cells of the mouse trachea and human airway epithelium.
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Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury.
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Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration.
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Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.
Yoshihiko Kobayashi, Aleksandra Tata, Arvind Konkimalla, Hiroaki Katsura, Rebecca F Lee, Jianhong Ou, Nicholas E Banovich, Jonathan A Kropski, Purushothama Rao Tata. Nat Cell Biol 2020
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Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function.
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Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis.
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Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis.
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Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition.
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The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future.
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Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis.
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The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.
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Local lung hypoxia determines epithelial fate decisions during alveolar regeneration.
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Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.
Hiroaki Katsura, Vishwaraj Sontake, Aleksandra Tata, Yoshihiko Kobayashi, Caitlin E Edwards, Brook E Heaton, Arvind Konkimalla, Takanori Asakura, Yu Mikami, Ethan J Fritch,[...]. Cell Stem Cell 2020
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p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.
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Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.
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Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung.
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Identification of bronchioalveolar stem cells in normal lung and lung cancer.
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Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection.
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Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung.
Jarod A Zepp, William J Zacharias, David B Frank, Christina A Cavanaugh, Su Zhou, Michael P Morley, Edward E Morrisey. Cell 2017
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Senescence of Alveolar Type 2 Cells Drives Progressive Pulmonary Fibrosis.
Changfu Yao, Xiangrong Guan, Gianni Carraro, Tanyalak Parimon, Xue Liu, Guanling Huang, Apoorva Mulay, Harmik J Soukiasian, Gregory David, Stephen S Weigt,[...]. Am J Respir Crit Care Med 2021
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Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation.
Mei-I Chung, Melissa Bujnis, Christina E Barkauskas, Yoshihiko Kobayashi, Brigid L M Hogan. Development 2018
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Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells.
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Jaymin J Kathiriya, Chaoqun Wang, Minqi Zhou, Alexis Brumwell, Monica Cassandras, Claude Jourdan Le Saux, Max Cohen, Kostantinos-Dionysios Alysandratos, Bruce Wang, Paul Wolters,[...]. Nat Cell Biol 2022
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Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis.
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13
Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.
Qiaozhen Liu, Kuo Liu, Guizhong Cui, Xiuzhen Huang, Shun Yao, Wenke Guo, Zhen Qin, Yan Li, Rui Yang, Wenjuan Pu,[...]. Nat Genet 2019
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13
Pulmonary alveolar type I cell population consists of two distinct subtypes that differ in cell fate.
Yanjie Wang, Zan Tang, Huanwei Huang, Jiao Li, Zheng Wang, Yuanyuan Yu, Chengwei Zhang, Juan Li, Huaping Dai, Fengchao Wang,[...]. Proc Natl Acad Sci U S A 2018
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Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration.
Jaymin J Kathiriya, Alexis N Brumwell, Julia R Jackson, Xiaodan Tang, Harold A Chapman. Cell Stem Cell 2020
Jaymin J Kathiriya, Alexis N Brumwell, Julia R Jackson, Xiaodan Tang, Harold A Chapman. Cell Stem Cell 2020
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A molecular cell atlas of the human lung from single-cell RNA sequencing.
Kyle J Travaglini, Ahmad N Nabhan, Lolita Penland, Rahul Sinha, Astrid Gillich, Rene V Sit, Stephen Chang, Stephanie D Conley, Yasuo Mori, Jun Seita,[...]. Nature 2020
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Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation.
David B Frank, Tien Peng, Jarod A Zepp, Melinda Snitow, Tiffaney L Vincent, Ian J Penkala, Zheng Cui, Michael J Herriges, Michael P Morley, Su Zhou,[...]. Cell Rep 2016
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Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2.
Jeonghwan Youk, Taewoo Kim, Kelly V Evans, Young-Il Jeong, Yongsuk Hur, Seon Pyo Hong, Je Hyoung Kim, Kijong Yi, Su Yeon Kim, Kwon Joong Na,[...]. Cell Stem Cell 2020
Jeonghwan Youk, Taewoo Kim, Kelly V Evans, Young-Il Jeong, Yongsuk Hur, Seon Pyo Hong, Je Hyoung Kim, Kijong Yi, Su Yeon Kim, Kwon Joong Na,[...]. Cell Stem Cell 2020
12
A molecular single-cell lung atlas of lethal COVID-19.
Johannes C Melms, Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore, Igor Katsyv, André F Rendeiro, Amit Dipak Amin, Denis Schapiro,[...]. Nature 2021
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Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling.
Katherine B McCauley, Finn Hawkins, Maria Serra, Dylan C Thomas, Anjali Jacob, Darrell N Kotton. Cell Stem Cell 2017
Katherine B McCauley, Finn Hawkins, Maria Serra, Dylan C Thomas, Anjali Jacob, Darrell N Kotton. Cell Stem Cell 2017
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Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling.
Jason R Rock, Scott H Randell, Brigid L M Hogan. Dis Model Mech 2010
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Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells.
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Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice.
Harold A Chapman, Xiaopeng Li, Jonathan P Alexander, Alexis Brumwell, Walter Lorizio, Kevin Tan, Arnoud Sonnenberg, Ying Wei, Thiennu H Vu. J Clin Invest 2011
Harold A Chapman, Xiaopeng Li, Jonathan P Alexander, Alexis Brumwell, Walter Lorizio, Kevin Tan, Arnoud Sonnenberg, Ying Wei, Thiennu H Vu. J Clin Invest 2011
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Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.
Paul A Reyfman, James M Walter, Nikita Joshi, Kishore R Anekalla, Alexandra C McQuattie-Pimentel, Stephen Chiu, Ramiro Fernandez, Mahzad Akbarpour, Ching-I Chen, Ziyou Ren,[...]. Am J Respir Crit Care Med 2019
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Cellular crosstalk in the development and regeneration of the respiratory system.
Jarod A Zepp, Edward E Morrisey. Nat Rev Mol Cell Biol 2019
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Spatial-Temporal Lineage Restrictions of Embryonic p63+ Progenitors Establish Distinct Stem Cell Pools in Adult Airways.
Ying Yang, Paul Riccio, Michael Schotsaert, Munemasa Mori, Jining Lu, Dong-Kee Lee, Adolfo García-Sastre, Jianming Xu, Wellington V Cardoso. Dev Cell 2018
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Ineffectual Type 2-to-Type 1 Alveolar Epithelial Cell Differentiation in Idiopathic Pulmonary Fibrosis: Persistence of the KRT8hi Transitional State.
Peng Jiang, Rafael Gil de Rubio, Steven M Hrycaj, Stephen J Gurczynski, Kent A Riemondy, Bethany B Moore, M Bishr Omary, Karen M Ridge, Rachel L Zemans. Am J Respir Crit Care Med 2020
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Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration.
Ian J Penkala, Derek C Liberti, Joshua Pankin, Aravind Sivakumar, Madison M Kremp, Sowmya Jayachandran, Jeremy Katzen, John P Leach, Rebecca Windmueller, Katharine Stolz,[...]. Cell Stem Cell 2021
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A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.
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Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6.
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Lung organoids: current uses and future promise.
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Long-term expanding human airway organoids for disease modeling.
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Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung.
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Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung.
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Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury.
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14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.