A citation-based method for searching scientific literature

Shuo-Chien Ling, Magdalini Polymenidou, Don W Cleveland. Neuron 2013
Times Cited: 1015







List of co-cited articles
1454 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
50

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
26

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
25

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
23

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
Magdalini Polymenidou, Clotilde Lagier-Tourenne, Kasey R Hutt, Stephanie C Huelga, Jacqueline Moran, Tiffany Y Liang, Shuo-Chien Ling, Eveline Sun, Edward Wancewicz, Curt Mazur,[...]. Nat Neurosci 2011
807
21

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Avinash Patel, Hyun O Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann,[...]. Cell 2015
19

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
19

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.
Jonathan P Ling, Olga Pletnikova, Juan C Troncoso, Philip C Wong. Science 2015
248
18

Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.
Ze'ev Melamed, Jone López-Erauskin, Michael W Baughn, Ouyang Zhang, Kevin Drenner, Ying Sun, Fernande Freyermuth, Moira A McMahon, Melinda S Beccari, Jon W Artates,[...]. Nat Neurosci 2019
160
18

Decoding ALS: from genes to mechanism.
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016
16

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
16

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
T J Kwiatkowski, D A Bosco, A L Leclerc, E Tamrazian, C R Vanderburg, C Russ, A Davis, J Gilchrist, E J Kasarskis, T Munsat,[...]. Science 2009
16

The Overlapping Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Yevgeniya A Abramzon, Pietro Fratta, Bryan J Traynor, Ruth Chia. Front Neurosci 2020
93
17

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
James R Tollervey, Tomaž Curk, Boris Rogelj, Michael Briese, Matteo Cereda, Melis Kayikci, Julian König, Tibor Hortobágyi, Agnes L Nishimura, Vera Zupunski,[...]. Nat Neurosci 2011
717
15

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair.
Joseph R Klim, Luis A Williams, Francesco Limone, Irune Guerra San Juan, Brandi N Davis-Dusenbery, Daniel A Mordes, Aaron Burberry, Michael J Steinbaugh, Kanchana K Gamage, Rory Kirchner,[...]. Nat Neurosci 2019
169
15

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Patrick G Needham, Katie E Copley, Bryan Hurtle, Bede Portz, Noah J Pyles,[...]. Neuron 2019
212
14

Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization.
Amandine Molliex, Jamshid Temirov, Jihun Lee, Maura Coughlin, Anderson P Kanagaraj, Hong Joo Kim, Tanja Mittag, J Paul Taylor. Cell 2015
13

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis.
Edor Kabashi, Paul N Valdmanis, Patrick Dion, Dan Spiegelman, Brendan J McConkey, Christine Vande Velde, Jean-Pierre Bouchard, Lucette Lacomblez, Ksenia Pochigaeva, Francois Salachas,[...]. Nat Genet 2008
13

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
Ching-Chieh Chou, Yi Zhang, Mfon E Umoh, Spencer W Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G Donlin-Asp, Yu Han Chen, Duc M Duong,[...]. Nat Neurosci 2018
263
13

Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019
185
13

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A Scarborough, Jennifer Moore, Zamia Diaz, Kyle S MacLea, Brian Freibaum, Songqing Li, Amandine Molliex,[...]. Nature 2013
943
12

Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration.
Edward B Lee, Virginia M-Y Lee, John Q Trojanowski. Nat Rev Neurosci 2011
443
12

C9orf72-mediated ALS and FTD: multiple pathways to disease.
Rubika Balendra, Adrian M Isaacs. Nat Rev Neurol 2018
272
12

Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Dylan T Murray, Masato Kato, Yi Lin, Kent R Thurber, Ivan Hung, Steven L McKnight, Robert Tycko. Cell 2017
376
11

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
Ke Zhang, Christopher J Donnelly, Aaron R Haeusler, Jonathan C Grima, James B Machamer, Peter Steinwald, Elizabeth L Daley, Sean J Miller, Kathleen M Cunningham, Svetlana Vidensky,[...]. Nature 2015
621
11

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Lin Guo, Hong Joo Kim, Hejia Wang, John Monaghan, Fernande Freyermuth, Julie C Sung, Kevin O'Donovan, Charlotte M Fare, Zamia Diaz, Nikita Singh,[...]. Cell 2018
249
11

Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.
Tariq Afroz, Eva-Maria Hock, Patrick Ernst, Chiara Foglieni, Melanie Jambeau, Larissa A B Gilhespy, Florent Laferriere, Zuzanna Maniecka, Andreas Plückthun, Peer Mittl,[...]. Nat Commun 2017
159
11

ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Alexander E Conicella, Gül H Zerze, Jeetain Mittal, Nicolas L Fawzi. Structure 2016
403
11

ALS Genetics: Gains, Losses, and Implications for Future Therapies.
Garam Kim, Olivia Gautier, Eduardo Tassoni-Tsuchida, X Rosa Ma, Aaron D Gitler. Neuron 2020
110
11

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis.
Archana Prasad, Vidhya Bharathi, Vishwanath Sivalingam, Amandeep Girdhar, Basant K Patel. Front Mol Neurosci 2019
253
10

ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43.
Eveline S Arnold, Shuo-Chien Ling, Stephanie C Huelga, Clotilde Lagier-Tourenne, Magdalini Polymenidou, Dara Ditsworth, Holly B Kordasiewicz, Melissa McAlonis-Downes, Oleksandr Platoshyn, Philippe A Parone,[...]. Proc Natl Acad Sci U S A 2013
280
10

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
10

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Ian R A Mackenzie, Eileen H Bigio, Paul G Ince, Felix Geser, Manuela Neumann, Nigel J Cairns, Linda K Kwong, Mark S Forman, John Ravits, Heather Stewart,[...]. Ann Neurol 2007
678
10

A new subtype of frontotemporal lobar degeneration with FUS pathology.
Manuela Neumann, Rosa Rademakers, Sigrun Roeber, Matt Baker, Hans A Kretzschmar, Ian R A Mackenzie. Brain 2009
517
10

Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
Zachary Monahan, Veronica H Ryan, Abigail M Janke, Kathleen A Burke, Shannon N Rhoads, Gül H Zerze, Robert O'Meally, Gregory L Dignon, Alexander E Conicella, Wenwei Zheng,[...]. EMBO J 2017
349
10

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
Joy Mitra, Erika N Guerrero, Pavana M Hegde, Nicole F Liachko, Haibo Wang, Velmarini Vasquez, Junling Gao, Arvind Pandey, J Paul Taylor, Brian C Kraemer,[...]. Proc Natl Acad Sci U S A 2019
125
10

Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Takuya Yoshizawa, Rustam Ali, Jenny Jiou, Ho Yee Joyce Fung, Kathleen A Burke, Seung Joong Kim, Yuan Lin, William B Peeples, Daniel Saltzberg, Michael Soniat,[...]. Cell 2018
175
10

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu,[...]. Nature 2010
836
10

TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
X Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C Vatsavayai, Garam Kim, Fred Harbinski, Adam Briner, Caitlin M Rodriguez, Caiwei Guo, Tetsuya Akiyama,[...]. Nature 2022
40
25

TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.
Brian S Johnson, David Snead, Jonathan J Lee, J Michael McCaffery, James Shorter, Aaron D Gitler. J Biol Chem 2009
505
10

TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
Alexander E Conicella, Gregory L Dignon, Gül H Zerze, Hermann Broder Schmidt, Alexandra M D'Ordine, Young C Kim, Rajat Rohatgi, Yuna M Ayala, Jeetain Mittal, Nicolas L Fawzi. Proc Natl Acad Sci U S A 2020
118
10

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Mario Hofweber, Saskia Hutten, Benjamin Bourgeois, Emil Spreitzer, Annika Niedner-Boblenz, Martina Schifferer, Marc-David Ruepp, Mikael Simons, Dierk Niessing, Tobias Madl,[...]. Cell 2018
316
9

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.
Tetsuro Murakami, Seema Qamar, Julie Qiaojin Lin, Gabriele S Kaminski Schierle, Eric Rees, Akinori Miyashita, Ana R Costa, Roger B Dodd, Fiona T S Chan, Claire H Michel,[...]. Neuron 2015
490
9

RNA-binding proteins with prion-like domains in health and disease.
Alice Ford Harrison, James Shorter. Biochem J 2017
233
9

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia.
Han-Xiang Deng, Wenjie Chen, Seong-Tshool Hong, Kym M Boycott, George H Gorrie, Nailah Siddique, Yi Yang, Faisal Fecto, Yong Shi, Hong Zhai,[...]. Nature 2011
824
9

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies.
Manuela Neumann, Linda K Kwong, Edward B Lee, Elisabeth Kremmer, Andrew Flatley, Yan Xu, Mark S Forman, Dirk Troost, Hans A Kretzschmar, John Q Trojanowski,[...]. Acta Neuropathol 2009
362
9


RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Shovamayee Maharana, Jie Wang, Dimitrios K Papadopoulos, Doris Richter, Andrey Pozniakovsky, Ina Poser, Marc Bickle, Sandra Rizk, Jordina Guillén-Boixet, Titus M Franzmann,[...]. Science 2018
495
9


HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells.
Haiyang Yu, Shan Lu, Kelsey Gasior, Digvijay Singh, Sonia Vazquez-Sanchez, Olga Tapia, Divek Toprani, Melinda S Beccari, John R Yates, Sandrine Da Cruz,[...]. Science 2021
86
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.