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Times Cited: 97
Times Cited: 97
Times Cited
Times Co-cited
Similarity
An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
Devarati Mitra, Xi Luo, Ann Morgan, Jin Wang, Mai P Hoang, Jennifer Lo, Candace R Guerrero, Jochen K Lennerz, Martin C Mihm, Jennifer A Wargo,[...]. Nature 2012
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A landscape of driver mutations in melanoma.
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Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytes.
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alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes.
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Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans.
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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
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Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.
Ana Luisa Kadekaro, Sancy Leachman, Renny J Kavanagh, Viki Swope, Pamela Cassidy, Dorothy Supp, Maureen Sartor, Sandy Schwemberger, George Babcock, Kazumasa Wakamatsu,[...]. FASEB J 2010
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Central role of p53 in the suntan response and pathologic hyperpigmentation.
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WWP2 is an E3 ubiquitin ligase for PTEN.
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Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
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Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation.
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Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.
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Germline MC1R status influences somatic mutation burden in melanoma.
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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
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alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage.
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Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?
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MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.
Jose C García-Borrón, Zalfa Abdel-Malek, Celia Jiménez-Cervantes. Pigment Cell Melanoma Res 2014
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Ubiquitination regulates PTEN nuclear import and tumor suppression.
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Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.
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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
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NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.
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Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress.
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MC1R, eumelanin and pheomelanin: their role in determining the susceptibility to skin cancer.
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PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.
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MC1R signaling. Intracellular partners and pathophysiological implications.
Cecilia Herraiz, Jose C Garcia-Borron, Celia Jiménez-Cervantes, Conchi Olivares. Biochim Biophys Acta Mol Basis Dis 2017
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X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization.
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A secreted PTEN phosphatase that enters cells to alter signaling and survival.
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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.
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Comprehensive evaluation of allele frequency differences of MC1R variants across populations.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.