Brandon H Toyama, Jeffrey N Savas, Sung Kyu Park, Michael S Harris, Nicholas T Ingolia, John R Yates, Martin W Hetzer. Cell 2013
Times Cited: 311
Times Cited: 311
Times Cited
Times Co-cited
Similarity
Extremely long-lived nuclear pore proteins in the rat brain.
Jeffrey N Savas, Brandon H Toyama, Tao Xu, John R Yates, Martin W Hetzer. Science 2012
Jeffrey N Savas, Brandon H Toyama, Tao Xu, John R Yates, Martin W Hetzer. Science 2012
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Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.
Maximiliano A D'Angelo, Marcela Raices, Siler H Panowski, Martin W Hetzer. Cell 2009
Maximiliano A D'Angelo, Marcela Raices, Siler H Panowski, Martin W Hetzer. Cell 2009
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Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions.
Eugenio F Fornasiero, Sunit Mandad, Hanna Wildhagen, Mihai Alevra, Burkhard Rammner, Sarva Keihani, Felipe Opazo, Inga Urban, Till Ischebeck, M Sadman Sakib,[...]. Nat Commun 2018
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The nuclear pore complex: understanding its function through structural insight.
Martin Beck, Ed Hurt. Nat Rev Mol Cell Biol 2017
Martin Beck, Ed Hurt. Nat Rev Mol Cell Biol 2017
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Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells.
Brandon H Toyama, Rafael Arrojo E Drigo, Varda Lev-Ram, Ranjan Ramachandra, Thomas J Deerinck, Claude Lechene, Mark H Ellisman, Martin W Hetzer. J Cell Biol 2019
Brandon H Toyama, Rafael Arrojo E Drigo, Varda Lev-Ram, Ranjan Ramachandra, Thomas J Deerinck, Claude Lechene, Mark H Ellisman, Martin W Hetzer. J Cell Biol 2019
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Systematic analysis of protein turnover in primary cells.
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Toby Mathieson, Holger Franken, Jan Kosinski, Nils Kurzawa, Nico Zinn, Gavain Sweetman, Daniel Poeckel, Vikram S Ratnu, Maike Schramm, Isabelle Becher,[...]. Nat Commun 2018
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The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
Ke Zhang, Christopher J Donnelly, Aaron R Haeusler, Jonathan C Grima, James B Machamer, Peter Steinwald, Elizabeth L Daley, Sean J Miller, Kathleen M Cunningham, Svetlana Vidensky,[...]. Nature 2015
Ke Zhang, Christopher J Donnelly, Aaron R Haeusler, Jonathan C Grima, James B Machamer, Peter Steinwald, Elizabeth L Daley, Sean J Miller, Kathleen M Cunningham, Svetlana Vidensky,[...]. Nature 2015
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Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Bahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, Alyssa Coyne, Julia Schiantarelli, Yari Carlomagno, Casey Cook, Sean J Miller, Simon Dujardin, Ana S Amaral,[...]. Neuron 2018
Bahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, Alyssa Coyne, Julia Schiantarelli, Yari Carlomagno, Casey Cook, Sean J Miller, Simon Dujardin, Ana S Amaral,[...]. Neuron 2018
14
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.
Ana Jovičić, Jerome Mertens, Steven Boeynaems, Elke Bogaert, Noori Chai, Shizuka B Yamada, Joseph W Paul, Shuying Sun, Joseph R Herdy, Gregor Bieri,[...]. Nat Neurosci 2015
Ana Jovičić, Jerome Mertens, Steven Boeynaems, Elke Bogaert, Noori Chai, Shizuka B Yamada, Joseph W Paul, Shuying Sun, Joseph R Herdy, Gregor Bieri,[...]. Nat Neurosci 2015
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Analysis of proteome dynamics in the mouse brain.
John C Price, Shenheng Guan, Alma Burlingame, Stanley B Prusiner, Sina Ghaemmaghami. Proc Natl Acad Sci U S A 2010
John C Price, Shenheng Guan, Alma Burlingame, Stanley B Prusiner, Sina Ghaemmaghami. Proc Natl Acad Sci U S A 2010
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TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
Ching-Chieh Chou, Yi Zhang, Mfon E Umoh, Spencer W Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G Donlin-Asp, Yu Han Chen, Duc M Duong,[...]. Nat Neurosci 2018
Ching-Chieh Chou, Yi Zhang, Mfon E Umoh, Spencer W Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G Donlin-Asp, Yu Han Chen, Duc M Duong,[...]. Nat Neurosci 2018
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The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
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Protein homeostasis: live long, won't prosper.
Brandon H Toyama, Martin W Hetzer. Nat Rev Mol Cell Biol 2013
Brandon H Toyama, Martin W Hetzer. Nat Rev Mol Cell Biol 2013
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Global quantification of mammalian gene expression control.
Björn Schwanhäusser, Dorothea Busse, Na Li, Gunnar Dittmar, Johannes Schuchhardt, Jana Wolf, Wei Chen, Matthias Selbach. Nature 2011
Björn Schwanhäusser, Dorothea Busse, Na Li, Gunnar Dittmar, Johannes Schuchhardt, Jana Wolf, Wei Chen, Matthias Selbach. Nature 2011
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Surveillance of nuclear pore complex assembly by ESCRT-III/Vps4.
Brant M Webster, Paolo Colombi, Jens Jäger, C Patrick Lusk. Cell 2014
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11
Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
Jerome Mertens, Apuã C M Paquola, Manching Ku, Emily Hatch, Lena Böhnke, Shauheen Ladjevardi, Sean McGrath, Benjamin Campbell, Hyungjun Lee, Joseph R Herdy,[...]. Cell Stem Cell 2015
Jerome Mertens, Apuã C M Paquola, Manching Ku, Emily Hatch, Lena Böhnke, Shauheen Ladjevardi, Sean McGrath, Benjamin Campbell, Hyungjun Lee, Joseph R Herdy,[...]. Cell Stem Cell 2015
10
Mutant Huntingtin Disrupts the Nuclear Pore Complex.
Jonathan C Grima, J Gavin Daigle, Nicolas Arbez, Kathleen C Cunningham, Ke Zhang, Joseph Ochaba, Charlene Geater, Eva Morozko, Jennifer Stocksdale, Jenna C Glatzer,[...]. Neuron 2017
Jonathan C Grima, J Gavin Daigle, Nicolas Arbez, Kathleen C Cunningham, Ke Zhang, Joseph Ochaba, Charlene Geater, Eva Morozko, Jennifer Stocksdale, Jenna C Glatzer,[...]. Neuron 2017
10
Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.
Andreas C Woerner, Frédéric Frottin, Daniel Hornburg, Li R Feng, Felix Meissner, Maria Patra, Jörg Tatzelt, Matthias Mann, Konstanze F Winklhofer, F Ulrich Hartl,[...]. Science 2016
Andreas C Woerner, Frédéric Frottin, Daniel Hornburg, Li R Feng, Felix Meissner, Maria Patra, Jörg Tatzelt, Matthias Mann, Konstanze F Winklhofer, F Ulrich Hartl,[...]. Science 2016
10
Lost in Transportation: Nucleocytoplasmic Transport Defects in ALS and Other Neurodegenerative Diseases.
Hong Joo Kim, J Paul Taylor. Neuron 2017
Hong Joo Kim, J Paul Taylor. Neuron 2017
10
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.
Brian D Freibaum, Yubing Lu, Rodrigo Lopez-Gonzalez, Nam Chul Kim, Sandra Almeida, Kyung-Ha Lee, Nisha Badders, Marc Valentine, Bruce L Miller, Philip C Wong,[...]. Nature 2015
Brian D Freibaum, Yubing Lu, Rodrigo Lopez-Gonzalez, Nam Chul Kim, Sandra Almeida, Kyung-Ha Lee, Nisha Badders, Marc Valentine, Bruce L Miller, Philip C Wong,[...]. Nature 2015
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Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles.
H Broder Schmidt, Dirk Görlich. Trends Biochem Sci 2016
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10
Structure and Assembly of the Nuclear Pore Complex.
Bernhard Hampoelz, Amparo Andres-Pons, Panagiotis Kastritis, Martin Beck. Annu Rev Biophys 2019
Bernhard Hampoelz, Amparo Andres-Pons, Panagiotis Kastritis, Martin Beck. Annu Rev Biophys 2019
12
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
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Old Proteins in Man: A Field in its Infancy.
Roger J W Truscott, Kevin L Schey, Michael G Friedrich. Trends Biochem Sci 2016
Roger J W Truscott, Kevin L Schey, Michael G Friedrich. Trends Biochem Sci 2016
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Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover.
Seok Heo, Graham H Diering, Chan Hyun Na, Raja Sekhar Nirujogi, Julia L Bachman, Akhilesh Pandey, Richard L Huganir. Proc Natl Acad Sci U S A 2018
Seok Heo, Graham H Diering, Chan Hyun Na, Raja Sekhar Nirujogi, Julia L Bachman, Akhilesh Pandey, Richard L Huganir. Proc Natl Acad Sci U S A 2018
12
Mapping the dynamic organization of the nuclear pore complex inside single living cells.
Gwénaël Rabut, Valérie Doye, Jan Ellenberg. Nat Cell Biol 2004
Gwénaël Rabut, Valérie Doye, Jan Ellenberg. Nat Cell Biol 2004
9
A change in nuclear pore complex composition regulates cell differentiation.
Maximiliano A D'Angelo, J Sebastian Gomez-Cavazos, Arianna Mei, Daniel H Lackner, Martin W Hetzer. Dev Cell 2012
Maximiliano A D'Angelo, J Sebastian Gomez-Cavazos, Arianna Mei, Daniel H Lackner, Martin W Hetzer. Dev Cell 2012
9
Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover.
Sidney B Cambridge, Florian Gnad, Chuong Nguyen, Justo Lorenzo Bermejo, Marcus Krüger, Matthias Mann. J Proteome Res 2011
Sidney B Cambridge, Florian Gnad, Chuong Nguyen, Justo Lorenzo Bermejo, Marcus Krüger, Matthias Mann. J Proteome Res 2011
9
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport.
Fatima Gasset-Rosa, Carlos Chillon-Marinas, Alexander Goginashvili, Ranjit Singh Atwal, Jonathan W Artates, Ricardos Tabet, Vanessa C Wheeler, Anne G Bang, Don W Cleveland, Clotilde Lagier-Tourenne. Neuron 2017
Fatima Gasset-Rosa, Carlos Chillon-Marinas, Alexander Goginashvili, Ranjit Singh Atwal, Jonathan W Artates, Ricardos Tabet, Vanessa C Wheeler, Anne G Bang, Don W Cleveland, Clotilde Lagier-Tourenne. Neuron 2017
8
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
8
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification.
Jürgen Cox, Matthias Mann. Nat Biotechnol 2008
Jürgen Cox, Matthias Mann. Nat Biotechnol 2008
8
Local and global influences on protein turnover in neurons and glia.
Aline R Dörrbaum, Lisa Kochen, Julian D Langer, Erin M Schuman. Elife 2018
Aline R Dörrbaum, Lisa Kochen, Julian D Langer, Erin M Schuman. Elife 2018
8
Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export.
Kevin Y Shi, Eiichiro Mori, Zehra F Nizami, Yi Lin, Masato Kato, Siheng Xiang, Leeju C Wu, Ming Ding, Yonghao Yu, Joseph G Gall,[...]. Proc Natl Acad Sci U S A 2017
Kevin Y Shi, Eiichiro Mori, Zehra F Nizami, Yi Lin, Masato Kato, Siheng Xiang, Leeju C Wu, Ming Ding, Yonghao Yu, Joseph G Gall,[...]. Proc Natl Acad Sci U S A 2017
7
An ESCRT-LEM protein surveillance system is poised to directly monitor the nuclear envelope and nuclear transport system.
David J Thaller, Matteo Allegretti, Sapan Borah, Paolo Ronchi, Martin Beck, C Patrick Lusk. Elife 2019
David J Thaller, Matteo Allegretti, Sapan Borah, Paolo Ronchi, Martin Beck, C Patrick Lusk. Elife 2019
12
Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells.
N Daigle, J Beaudouin, L Hartnell, G Imreh, E Hallberg, J Lippincott-Schwartz, J Ellenberg. J Cell Biol 2001
N Daigle, J Beaudouin, L Hartnell, G Imreh, E Hallberg, J Lippincott-Schwartz, J Ellenberg. J Cell Biol 2001
7
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.
Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana M Mitrea, Mohona Sarkar, Brian D Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex,[...]. Cell 2016
Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana M Mitrea, Mohona Sarkar, Brian D Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex,[...]. Cell 2016
7
Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines.
Alessandro Ori, Niccolò Banterle, Murat Iskar, Amparo Andrés-Pons, Claudia Escher, Huy Khanh Bui, Lenore Sparks, Victor Solis-Mezarino, Oliver Rinner, Peer Bork,[...]. Mol Syst Biol 2013
Alessandro Ori, Niccolò Banterle, Murat Iskar, Amparo Andrés-Pons, Claudia Escher, Huy Khanh Bui, Lenore Sparks, Victor Solis-Mezarino, Oliver Rinner, Peer Bork,[...]. Mol Syst Biol 2013
7
Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life.
Niels Lynnerup, Henrik Kjeldsen, Steffen Heegaard, Christina Jacobsen, Jan Heinemeier. PLoS One 2008
Niels Lynnerup, Henrik Kjeldsen, Steffen Heegaard, Christina Jacobsen, Jan Heinemeier. PLoS One 2008
7
Age Mosaicism across Multiple Scales in Adult Tissues.
Rafael Arrojo E Drigo, Varda Lev-Ram, Swati Tyagi, Ranjan Ramachandra, Thomas Deerinck, Eric Bushong, Sebastien Phan, Victoria Orphan, Claude Lechene, Mark H Ellisman,[...]. Cell Metab 2019
Rafael Arrojo E Drigo, Varda Lev-Ram, Swati Tyagi, Ranjan Ramachandra, Thomas Deerinck, Eric Bushong, Sebastien Phan, Victoria Orphan, Claude Lechene, Mark H Ellisman,[...]. Cell Metab 2019
14
The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome.
Mario Niepel, Kelly R Molloy, Rosemary Williams, Julia C Farr, Anne C Meinema, Nicholas Vecchietti, Ileana M Cristea, Brian T Chait, Michael P Rout, Caterina Strambio-De-Castillia. Mol Biol Cell 2013
Mario Niepel, Kelly R Molloy, Rosemary Williams, Julia C Farr, Anne C Meinema, Nicholas Vecchietti, Ileana M Cristea, Brian T Chait, Michael P Rout, Caterina Strambio-De-Castillia. Mol Biol Cell 2013
10
Chm7 and Heh1 collaborate to link nuclear pore complex quality control with nuclear envelope sealing.
Brant M Webster, David J Thaller, Jens Jäger, Sarah E Ochmann, Sapan Borah, C Patrick Lusk. EMBO J 2016
Brant M Webster, David J Thaller, Jens Jäger, Sarah E Ochmann, Sapan Borah, C Patrick Lusk. EMBO J 2016
10
The roles of the nuclear pore complex in cellular dysfunction, aging and disease.
Stephen Sakuma, Maximiliano A D'Angelo. Semin Cell Dev Biol 2017
Stephen Sakuma, Maximiliano A D'Angelo. Semin Cell Dev Biol 2017
13
Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells.
Tomohisa Toda, Jonathan Y Hsu, Sara B Linker, Lauren Hu, Simon T Schafer, Jerome Mertens, Filipe V Jacinto, Martin W Hetzer, Fred H Gage. Cell Stem Cell 2017
Tomohisa Toda, Jonathan Y Hsu, Sara B Linker, Lauren Hu, Simon T Schafer, Jerome Mertens, Filipe V Jacinto, Martin W Hetzer, Fred H Gage. Cell Stem Cell 2017
11
The nuclear pore complex: bridging nuclear transport and gene regulation.
Caterina Strambio-De-Castillia, Mario Niepel, Michael P Rout. Nat Rev Mol Cell Biol 2010
Caterina Strambio-De-Castillia, Mario Niepel, Michael P Rout. Nat Rev Mol Cell Biol 2010
7
Selective autophagy degrades nuclear pore complexes.
Chia-Wei Lee, Florian Wilfling, Paolo Ronchi, Matteo Allegretti, Shyamal Mosalaganti, Stefan Jentsch, Martin Beck, Boris Pfander. Nat Cell Biol 2020
Chia-Wei Lee, Florian Wilfling, Paolo Ronchi, Matteo Allegretti, Shyamal Mosalaganti, Stefan Jentsch, Martin Beck, Boris Pfander. Nat Cell Biol 2020
15
The Structure of the Nuclear Pore Complex (An Update).
Daniel H Lin, André Hoelz. Annu Rev Biochem 2019
Daniel H Lin, André Hoelz. Annu Rev Biochem 2019
7
Integrative structure and functional anatomy of a nuclear pore complex.
Seung Joong Kim, Javier Fernandez-Martinez, Ilona Nudelman, Yi Shi, Wenzhu Zhang, Barak Raveh, Thurston Herricks, Brian D Slaughter, Joanna A Hogan, Paula Upla,[...]. Nature 2018
Seung Joong Kim, Javier Fernandez-Martinez, Ilona Nudelman, Yi Shi, Wenzhu Zhang, Barak Raveh, Thurston Herricks, Brian D Slaughter, Joanna A Hogan, Paula Upla,[...]. Nature 2018
6
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
Steven Boeynaems, Elke Bogaert, Emiel Michiels, Ilse Gijselinck, Anne Sieben, Ana Jovičić, Greet De Baets, Wendy Scheveneels, Jolien Steyaert, Ivy Cuijt,[...]. Sci Rep 2016
Steven Boeynaems, Elke Bogaert, Emiel Michiels, Ilse Gijselinck, Anne Sieben, Ana Jovičić, Greet De Baets, Wendy Scheveneels, Jolien Steyaert, Ivy Cuijt,[...]. Sci Rep 2016
6
FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties.
Steffen Frey, Ralf P Richter, Dirk Görlich. Science 2006
Steffen Frey, Ralf P Richter, Dirk Görlich. Science 2006
6
The Nuclear Pore Complex as a Flexible and Dynamic Gate.
Kevin E Knockenhauer, Thomas U Schwartz. Cell 2016
Kevin E Knockenhauer, Thomas U Schwartz. Cell 2016
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.