A citation-based method for searching scientific literature

Naoko Takebe, Dat Nguyen, Sherry X Yang. Pharmacol Ther 2014
Times Cited: 264







List of co-cited articles
1014 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Notch signalling in solid tumours: a little bit of everything but not all the time.
Prathibha Ranganathan, Kelly L Weaver, Anthony J Capobianco. Nat Rev Cancer 2011
561
16

The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
280
15

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
516
15

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
13

Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
314
12

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update.
Naoko Takebe, Lucio Miele, Pamela Jo Harris, Woondong Jeong, Hideaki Bando, Michael Kahn, Sherry X Yang, S Percy Ivy. Nat Rev Clin Oncol 2015
735
12

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
11

Aberrant activation of notch signaling in human breast cancer.
Spyros Stylianou, Rob B Clarke, Keith Brennan. Cancer Res 2006
412
11

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival.
Michael Reedijk, Silvia Odorcic, Lynn Chang, Hui Zhang, Naomi Miller, David R McCready, Gina Lockwood, Sean E Egan. Cancer Res 2005
560
11

Notch Signaling in Development, Tissue Homeostasis, and Disease.
Chris Siebel, Urban Lendahl. Physiol Rev 2017
352
10

Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors.
Anthony W Tolcher, Wells A Messersmith, Stanislaw M Mikulski, Kyriakos P Papadopoulos, Eunice L Kwak, Darlene G Gibbon, Amita Patnaik, Gerald S Falchook, Arvind Dasari, Geoffrey I Shapiro,[...]. J Clin Oncol 2012
175
9


Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy.
Shannon M McAuliffe, Stefanie L Morgan, Gregory A Wyant, Lieu T Tran, Katherine W Muto, Yu Sarah Chen, Kenneth T Chin, Justin C Partridge, Barish B Poole, Kuang-Hung Cheng,[...]. Proc Natl Acad Sci U S A 2012
226
8

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H van Es, Marielle E van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J Winton, Freddy Radtke,[...]. Nature 2005
8

Notch signaling: an emerging therapeutic target for cancer treatment.
Xun Yuan, Hua Wu, Hanxiao Xu, Huihua Xiong, Qian Chu, Shiying Yu, Gen Sheng Wu, Kongming Wu. Cancer Lett 2015
228
8

Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
559
8

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.
Bruno M Simões, Ciara S O'Brien, Rachel Eyre, Andreia Silva, Ling Yu, Aida Sarmiento-Castro, Denis G Alférez, Kath Spence, Angélica Santiago-Gómez, Francesca Chemi,[...]. Cell Rep 2015
114
8

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
8

Notch signaling: simplicity in design, versatility in function.
Emma R Andersson, Rickard Sandberg, Urban Lendahl. Development 2011
617
7

A phase II study of RO4929097 in metastatic colorectal cancer.
Jonathan R Strosberg, Timothy Yeatman, Jill Weber, Domenico Coppola, Michael J Schell, Gang Han, Khaldoun Almhanna, Richard Kim, Tiffany Valone, Helen Jump,[...]. Eur J Cancer 2012
91
7

Hypoxia requires notch signaling to maintain the undifferentiated cell state.
Maria V Gustafsson, Xiaowei Zheng, Teresa Pereira, Katarina Gradin, Shaobo Jin, Johan Lundkvist, Jorge L Ruas, Lorenz Poellinger, Urban Lendahl, Maria Bondesson. Dev Cell 2005
806
7

Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors.
Ian Krop, Tim Demuth, Tina Guthrie, Patrick Y Wen, Warren P Mason, Prakash Chinnaiyan, Nicholas Butowski, Morris D Groves, Santosh Kesari, Steven J Freedman,[...]. J Clin Oncol 2012
214
7

Gamma secretase inhibitors of Notch signaling.
Roma Olsauskas-Kuprys, Andrei Zlobin, Clodia Osipo. Onco Targets Ther 2013
108
7

A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014.
Wells A Messersmith, Geoffrey I Shapiro, James M Cleary, Antonio Jimeno, Arvind Dasari, Bo Huang, M Naveed Shaik, Rossano Cesari, Xianxian Zheng, Jennifer M Reynolds,[...]. Clin Cancer Res 2015
126
7

A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors.
Elena Gabriela Chiorean, Patricia LoRusso, Robert Matthew Strother, Jennifer R Diamond, Anne Younger, Wells A Messersmith, Lieve Adriaens, Liming Liu, Richard J Kao, Albert Thomas DiCioccio,[...]. Clin Cancer Res 2015
79
8

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.
Irene Noguera-Troise, Christopher Daly, Nicholas J Papadopoulos, Sandra Coetzee, Pat Boland, Nicholas W Gale, Hsin Chieh Lin, George D Yancopoulos, Gavin Thurston. Nature 2006
774
7

Notch signalling in context.
Sarah J Bray. Nat Rev Mol Cell Biol 2016
479
7

Notch3 overexpression as potential therapeutic target in advanced stage chemoresistant ovarian cancer.
Mohammed Tanjimur Rahman, Kentaro Nakayama, Munmun Rahman, Hiroshi Katagiri, Atsuko Katagiri, Tomoka Ishibashi, Masako Ishikawa, Kouji Iida, Satoru Nakayama, Yoshiro Otsuki,[...]. Am J Clin Pathol 2012
48
12

Notch signalling: a simple pathway becomes complex.
Sarah J Bray. Nat Rev Mol Cell Biol 2006
6

Notch inhibitors for cancer treatment.
Ingrid Espinoza, Lucio Miele. Pharmacol Ther 2013
199
6

Notch signaling in human development and disease.
Andrea L Penton, Laura D Leonard, Nancy B Spinner. Semin Cell Dev Biol 2012
206
6

Notch signaling at a glance.
Kazuya Hori, Anindya Sen, Spyros Artavanis-Tsakonas. J Cell Sci 2013
348
6

Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses.
Diana J Azzam, Dekuang Zhao, Jun Sun, Andy J Minn, Prathibha Ranganathan, Katherine Drews-Elger, Xiaoqing Han, Manuel Picon-Ruiz, Candace A Gilbert, Seth A Wander,[...]. EMBO Mol Med 2013
52
11

A Role for Notch Signalling in Breast Cancer and Endocrine Resistance.
Ahmet Acar, Bruno M Simões, Robert B Clarke, Keith Brennan. Stem Cells Int 2016
38
15

Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis).
Shivaani Kummar, Geraldine O'Sullivan Coyne, Khanh T Do, Baris Turkbey, Paul S Meltzer, Eric Polley, Peter L Choyke, Robert Meehan, Rasa Vilimas, Yvonne Horneffer,[...]. J Clin Oncol 2017
81
7

Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways.
Mirjam C Boelens, Tony J Wu, Barzin Y Nabet, Bihui Xu, Yu Qiu, Taewon Yoon, Diana J Azzam, Christina Twyman-Saint Victor, Brianne Z Wiemann, Hemant Ishwaran,[...]. Cell 2014
499
6

Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.
Hannah Harrison, Gillian Farnie, Sacha J Howell, Rebecca E Rock, Spyros Stylianou, Keith R Brennan, Nigel J Bundred, Robert B Clarke. Cancer Res 2010
366
6

PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor.
Kai Wang, Qin Zhang, Danan Li, Keith Ching, Cathy Zhang, Xianxian Zheng, Mark Ozeck, Stephanie Shi, Xiaorong Li, Hui Wang,[...]. Clin Cancer Res 2015
91
6

A monoclonal antibody against human Notch1 ligand-binding domain depletes subpopulation of putative breast cancer stem-like cells.
Ankur Sharma, Anurag N Paranjape, Annapoorni Rangarajan, Rajan R Dighe. Mol Cancer Ther 2012
71
8

NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype.
Mizuki Yamamoto, Yuu Taguchi, Taku Ito-Kureha, Kentaro Semba, Noritaka Yamaguchi, Jun-ichiro Inoue. Nat Commun 2013
121
6

Notch as a tumour suppressor.
Craig S Nowell, Freddy Radtke. Nat Rev Cancer 2017
192
6

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Mats Hellström, Li-Kun Phng, Jennifer J Hofmann, Elisabet Wallgard, Leigh Coultas, Per Lindblom, Jackelyn Alva, Ann-Katrin Nilsson, Linda Karlsson, Nicholas Gaiano,[...]. Nature 2007
6

Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer.
Pasquale Sansone, Claudio Ceccarelli, Marjan Berishaj, Qing Chang, Vinagolu K Rajasekhar, Fabiana Perna, Robert L Bowman, Michele Vidone, Laura Daly, Jennifer Nnoli,[...]. Nat Commun 2016
109
6

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
494
6

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
592
6

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
6

The role of Notch and gamma-secretase inhibition in an ovarian cancer model.
Monjri M Shah, Marielba Zerlin, Blake Y Li, Thomas J Herzog, Jan K Kitajewski, Jason D Wright. Anticancer Res 2013
19
26

Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study.
Charles M Rudin, M Catherine Pietanza, Todd M Bauer, Neal Ready, Daniel Morgensztern, Bonnie S Glisson, Lauren A Byers, Melissa L Johnson, Howard A Burris, Francisco Robert,[...]. Lancet Oncol 2017
280
5

Notch3 overexpression is related to the recurrence of ovarian cancer and confers resistance to carboplatin.
Joon Tae Park, Xu Chen, Claes G Tropè, Ben Davidson, Ie-Ming Shih, Tian-Li Wang. Am J Pathol 2010
129
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.