John Kenneth Eykelenboom, Emma Christina Harte, Lynn Canavan, Ana Pastor-Peidro, Irene Calvo-Asensio, Marta Llorens-Agost, Noel Francis Lowndes. Cell Rep 2013
Times Cited: 66
Times Cited: 66
Times Cited
Times Co-cited
Similarity
ATR prohibits replication catastrophe by preventing global exhaustion of RPA.
Luis Ignacio Toledo, Matthias Altmeyer, Maj-Britt Rask, Claudia Lukas, Dorthe Helena Larsen, Lou Klitgaard Povlsen, Simon Bekker-Jensen, Niels Mailand, Jiri Bartek, Jiri Lukas. Cell 2013
Luis Ignacio Toledo, Matthias Altmeyer, Maj-Britt Rask, Claudia Lukas, Dorthe Helena Larsen, Lou Klitgaard Povlsen, Simon Bekker-Jensen, Niels Mailand, Jiri Bartek, Jiri Lukas. Cell 2013
45
Causes and consequences of replication stress.
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
42
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress.
Claudia Lukas, Velibor Savic, Simon Bekker-Jensen, Carsten Doil, Beate Neumann, Ronni Sølvhøj Pedersen, Merete Grøfte, Kok Lung Chan, Ian David Hickson, Jiri Bartek,[...]. Nat Cell Biol 2011
Claudia Lukas, Velibor Savic, Simon Bekker-Jensen, Carsten Doil, Beate Neumann, Ronni Sølvhøj Pedersen, Merete Grøfte, Kok Lung Chan, Ian David Hickson, Jiri Bartek,[...]. Nat Cell Biol 2011
33
Replication stress activates DNA repair synthesis in mitosis.
Sheroy Minocherhomji, Songmin Ying, Victoria A Bjerregaard, Sara Bursomanno, Aiste Aleliunaite, Wei Wu, Hocine W Mankouri, Huahao Shen, Ying Liu, Ian D Hickson. Nature 2015
Sheroy Minocherhomji, Songmin Ying, Victoria A Bjerregaard, Sara Bursomanno, Aiste Aleliunaite, Wei Wu, Hocine W Mankouri, Huahao Shen, Ying Liu, Ian D Hickson. Nature 2015
31
Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase.
Rémi Buisson, Jessica L Boisvert, Cyril H Benes, Lee Zou. Mol Cell 2015
Rémi Buisson, Jessica L Boisvert, Cyril H Benes, Lee Zou. Mol Cell 2015
30
ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis.
Valeria Naim, Therese Wilhelm, Michelle Debatisse, Filippo Rosselli. Nat Cell Biol 2013
Valeria Naim, Therese Wilhelm, Michelle Debatisse, Filippo Rosselli. Nat Cell Biol 2013
27
Replication stress and cancer.
Hélène Gaillard, Tatiana García-Muse, Andrés Aguilera. Nat Rev Cancer 2015
Hélène Gaillard, Tatiana García-Muse, Andrés Aguilera. Nat Rev Cancer 2015
27
An intrinsic S/G2 checkpoint enforced by ATR.
Joshua C Saldivar, Stephan Hamperl, Michael J Bocek, Mingyu Chung, Thomas E Bass, Fernanda Cisneros-Soberanis, Kumiko Samejima, Linfeng Xie, James R Paulson, William C Earnshaw,[...]. Science 2018
Joshua C Saldivar, Stephan Hamperl, Michael J Bocek, Mingyu Chung, Thomas E Bass, Fernanda Cisneros-Soberanis, Kumiko Samejima, Linfeng Xie, James R Paulson, William C Earnshaw,[...]. Science 2018
27
ATR disruption leads to chromosomal fragmentation and early embryonic lethality.
E J Brown, D Baltimore. Genes Dev 2000
E J Brown, D Baltimore. Genes Dev 2000
25
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
Randi G Syljuåsen, Claus Storgaard Sørensen, Lasse Tengbjerg Hansen, Kasper Fugger, Cecilia Lundin, Fredrik Johansson, Thomas Helleday, Maxwell Sehested, Jiri Lukas, Jiri Bartek. Mol Cell Biol 2005
Randi G Syljuåsen, Claus Storgaard Sørensen, Lasse Tengbjerg Hansen, Kasper Fugger, Cecilia Lundin, Fredrik Johansson, Thomas Helleday, Maxwell Sehested, Jiri Lukas, Jiri Bartek. Mol Cell Biol 2005
25
Nucleotide deficiency promotes genomic instability in early stages of cancer development.
Assaf C Bester, Maayan Roniger, Yifat S Oren, Michael M Im, Dan Sarni, Malka Chaoat, Aaron Bensimon, Gideon Zamir, Donna S Shewach, Batsheva Kerem. Cell 2011
Assaf C Bester, Maayan Roniger, Yifat S Oren, Michael M Im, Dan Sarni, Malka Chaoat, Aaron Bensimon, Gideon Zamir, Donna S Shewach, Batsheva Kerem. Cell 2011
25
The essential kinase ATR: ensuring faithful duplication of a challenging genome.
Joshua C Saldivar, David Cortez, Karlene A Cimprich. Nat Rev Mol Cell Biol 2017
Joshua C Saldivar, David Cortez, Karlene A Cimprich. Nat Rev Mol Cell Biol 2017
25
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.
Frank B Couch, Carol E Bansbach, Robert Driscoll, Jessica W Luzwick, Gloria G Glick, Rémy Bétous, Clinton M Carroll, Sung Yun Jung, Jun Qin, Karlene A Cimprich,[...]. Genes Dev 2013
Frank B Couch, Carol E Bansbach, Robert Driscoll, Jessica W Luzwick, Gloria G Glick, Rémy Bétous, Clinton M Carroll, Sung Yun Jung, Jun Qin, Karlene A Cimprich,[...]. Genes Dev 2013
24
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.
Lee Zou, Stephen J Elledge. Science 2003
Lee Zou, Stephen J Elledge. Science 2003
24
MUS81 promotes common fragile site expression.
Songmin Ying, Sheroy Minocherhomji, Kok Lung Chan, Timea Palmai-Pallag, Wai Kit Chu, Theresa Wass, Hocine W Mankouri, Ying Liu, Ian D Hickson. Nat Cell Biol 2013
Songmin Ying, Sheroy Minocherhomji, Kok Lung Chan, Timea Palmai-Pallag, Wai Kit Chu, Theresa Wass, Hocine W Mankouri, Ying Liu, Ian D Hickson. Nat Cell Biol 2013
24
Replication stress induces 53BP1-containing OPT domains in G1 cells.
Jeanine A Harrigan, Rimma Belotserkovskaya, Julia Coates, Daniela S Dimitrova, Sophie E Polo, Charles R Bradshaw, Peter Fraser, Stephen P Jackson. J Cell Biol 2011
Jeanine A Harrigan, Rimma Belotserkovskaya, Julia Coates, Daniela S Dimitrova, Sophie E Polo, Charles R Bradshaw, Peter Fraser, Stephen P Jackson. J Cell Biol 2011
22
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.
Kok Lung Chan, Timea Palmai-Pallag, Songmin Ying, Ian D Hickson. Nat Cell Biol 2009
Kok Lung Chan, Timea Palmai-Pallag, Songmin Ying, Ian D Hickson. Nat Cell Biol 2009
22
A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations.
Luis I Toledo, Matilde Murga, Rafal Zur, Rebeca Soria, Antonio Rodriguez, Sonia Martinez, Julen Oyarzabal, Joaquin Pastor, James R Bischoff, Oscar Fernandez-Capetillo. Nat Struct Mol Biol 2011
Luis I Toledo, Matilde Murga, Rafal Zur, Rebeca Soria, Antonio Rodriguez, Sonia Martinez, Julen Oyarzabal, Joaquin Pastor, James R Bischoff, Oscar Fernandez-Capetillo. Nat Struct Mol Biol 2011
21
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges.
Kok-Lung Chan, Phillip S North, Ian D Hickson. EMBO J 2007
Kok-Lung Chan, Phillip S North, Ian D Hickson. EMBO J 2007
19
Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR.
Philip M Reaper, Matthew R Griffiths, Joanna M Long, Jean-Damien Charrier, Somhairle Maccormick, Peter A Charlton, Julian M C Golec, John R Pollard. Nat Chem Biol 2011
Philip M Reaper, Matthew R Griffiths, Joanna M Long, Jean-Damien Charrier, Somhairle Maccormick, Peter A Charlton, Julian M C Golec, John R Pollard. Nat Chem Biol 2011
19
Chk1 promotes replication fork progression by controlling replication initiation.
Eva Petermann, Mick Woodcock, Thomas Helleday. Proc Natl Acad Sci U S A 2010
Eva Petermann, Mick Woodcock, Thomas Helleday. Proc Natl Acad Sci U S A 2010
19
RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress.
Rahul Bhowmick, Sheroy Minocherhomji, Ian D Hickson. Mol Cell 2016
Rahul Bhowmick, Sheroy Minocherhomji, Ian D Hickson. Mol Cell 2016
19
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C Zoumpourlis,[...]. Nature 2006
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C Zoumpourlis,[...]. Nature 2006
18
PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint.
Christoph Baumann, Roman Körner, Kay Hofmann, Erich A Nigg. Cell 2007
Christoph Baumann, Roman Körner, Kay Hofmann, Erich A Nigg. Cell 2007
18
Replication stress links structural and numerical cancer chromosomal instability.
Rebecca A Burrell, Sarah E McClelland, David Endesfelder, Petra Groth, Marie-Christine Weller, Nadeem Shaikh, Enric Domingo, Nnennaya Kanu, Sally M Dewhurst, Eva Gronroos,[...]. Nature 2013
Rebecca A Burrell, Sarah E McClelland, David Endesfelder, Petra Groth, Marie-Christine Weller, Nadeem Shaikh, Enric Domingo, Nnennaya Kanu, Sally M Dewhurst, Eva Gronroos,[...]. Nature 2013
18
An oncogene-induced DNA damage model for cancer development.
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
18
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Jirina Bartkova, Zuzana Horejsí, Karen Koed, Alwin Krämer, Frederic Tort, Karsten Zieger, Per Guldberg, Maxwell Sehested, Jahn M Nesland, Claudia Lukas,[...]. Nature 2005
Jirina Bartkova, Zuzana Horejsí, Karen Koed, Alwin Krämer, Frederic Tort, Karsten Zieger, Per Guldberg, Maxwell Sehested, Jahn M Nesland, Claudia Lukas,[...]. Nature 2005
18
DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis.
Valérie Bergoglio, Anne-Sophie Boyer, Erin Walsh, Valeria Naim, Gaëlle Legube, Marietta Y W T Lee, Laurie Rey, Filippo Rosselli, Christophe Cazaux, Kristin A Eckert,[...]. J Cell Biol 2013
Valérie Bergoglio, Anne-Sophie Boyer, Erin Walsh, Valeria Naim, Gaëlle Legube, Marietta Y W T Lee, Laurie Rey, Filippo Rosselli, Christophe Cazaux, Kristin A Eckert,[...]. J Cell Biol 2013
18
ATR regulates fragile site stability.
Anne M Casper, Paul Nghiem, Martin F Arlt, Thomas W Glover. Cell 2002
Anne M Casper, Paul Nghiem, Martin F Arlt, Thomas W Glover. Cell 2002
16
Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity.
Stéphane Koundrioukoff, Sandra Carignon, Hervé Técher, Anne Letessier, Olivier Brison, Michelle Debatisse. PLoS Genet 2013
Stéphane Koundrioukoff, Sandra Carignon, Hervé Técher, Anne Letessier, Olivier Brison, Michelle Debatisse. PLoS Genet 2013
16
DNA replication origin activation in space and time.
Michalis Fragkos, Olivier Ganier, Philippe Coulombe, Marcel Méchali. Nat Rev Mol Cell Biol 2015
Michalis Fragkos, Olivier Ganier, Philippe Coulombe, Marcel Méchali. Nat Rev Mol Cell Biol 2015
16
DNA replication stress as a hallmark of cancer.
Morgane Macheret, Thanos D Halazonetis. Annu Rev Pathol 2015
Morgane Macheret, Thanos D Halazonetis. Annu Rev Pathol 2015
16
DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.
Bennie Lemmens, Nadia Hegarat, Karen Akopyan, Joan Sala-Gaston, Jiri Bartek, Helfrid Hochegger, Arne Lindqvist. Mol Cell 2018
Bennie Lemmens, Nadia Hegarat, Karen Akopyan, Joan Sala-Gaston, Jiri Bartek, Helfrid Hochegger, Arne Lindqvist. Mol Cell 2018
20
Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.
Matilde Murga, Stefano Campaner, Andres J Lopez-Contreras, Luis I Toledo, Rebeca Soria, Maria F Montaña, Luana D' Artista, Thomas Schleker, Carmen Guerra, Elena Garcia,[...]. Nat Struct Mol Biol 2011
Matilde Murga, Stefano Campaner, Andres J Lopez-Contreras, Luis I Toledo, Rebeca Soria, Maria F Montaña, Luana D' Artista, Thomas Schleker, Carmen Guerra, Elena Garcia,[...]. Nat Struct Mol Biol 2011
15
The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities.
Valeria Naim, Filippo Rosselli. Nat Cell Biol 2009
Valeria Naim, Filippo Rosselli. Nat Cell Biol 2009
15
ATR: an essential regulator of genome integrity.
Karlene A Cimprich, David Cortez. Nat Rev Mol Cell Biol 2008
Karlene A Cimprich, David Cortez. Nat Rev Mol Cell Biol 2008
15
Replication stress and cancer: it takes two to tango.
Emilio Lecona, Oscar Fernández-Capetillo. Exp Cell Res 2014
Emilio Lecona, Oscar Fernández-Capetillo. Exp Cell Res 2014
15
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.
Tony S Byun, Marcin Pacek, Muh-ching Yee, Johannes C Walter, Karlene A Cimprich. Genes Dev 2005
Tony S Byun, Marcin Pacek, Muh-ching Yee, Johannes C Walter, Karlene A Cimprich. Genes Dev 2005
15
DNA replication and oncogene-induced replicative stress.
Stephanie A Hills, John F X Diffley. Curr Biol 2014
Stephanie A Hills, John F X Diffley. Curr Biol 2014
15
A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.
Sergio Ruiz, Cristina Mayor-Ruiz, Vanesa Lafarga, Matilde Murga, Maria Vega-Sendino, Sagrario Ortega, Oscar Fernandez-Capetillo. Mol Cell 2016
Sergio Ruiz, Cristina Mayor-Ruiz, Vanesa Lafarga, Matilde Murga, Maria Vega-Sendino, Sagrario Ortega, Oscar Fernandez-Capetillo. Mol Cell 2016
15
The impact of replication stress on replication dynamics and DNA damage in vertebrate cells.
Hervé Técher, Stéphane Koundrioukoff, Alain Nicolas, Michelle Debatisse. Nat Rev Genet 2017
Hervé Técher, Stéphane Koundrioukoff, Alain Nicolas, Michelle Debatisse. Nat Rev Genet 2017
15
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.
A de Klein, M Muijtjens, R van Os, Y Verhoeven, B Smit, A M Carr, A R Lehmann, J H Hoeijmakers. Curr Biol 2000
A de Klein, M Muijtjens, R van Os, Y Verhoeven, B Smit, A M Carr, A R Lehmann, J H Hoeijmakers. Curr Biol 2000
13
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging.
Matilde Murga, Samuel Bunting, Maria F Montaña, Rebeca Soria, Francisca Mulero, Marta Cañamero, Youngsoo Lee, Peter J McKinnon, Andre Nussenzweig, Oscar Fernandez-Capetillo. Nat Genet 2009
Matilde Murga, Samuel Bunting, Maria F Montaña, Rebeca Soria, Francisca Mulero, Marta Cañamero, Youngsoo Lee, Peter J McKinnon, Andre Nussenzweig, Oscar Fernandez-Capetillo. Nat Genet 2009
13
Break-induced replication repair of damaged forks induces genomic duplications in human cells.
Lorenzo Costantino, Sotirios K Sotiriou, Juha K Rantala, Simon Magin, Emil Mladenov, Thomas Helleday, James E Haber, George Iliakis, Olli P Kallioniemi, Thanos D Halazonetis. Science 2014
Lorenzo Costantino, Sotirios K Sotiriou, Juha K Rantala, Simon Magin, Emil Mladenov, Thomas Helleday, James E Haber, George Iliakis, Olli P Kallioniemi, Thanos D Halazonetis. Science 2014
13
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.
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13
Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption.
Halfdan Beck, Viola Nähse-Kumpf, Marie Sofie Yoo Larsen, Karen A O'Hanlon, Sebastian Patzke, Christian Holmberg, Jakob Mejlvang, Anja Groth, Olaf Nielsen, Randi G Syljuåsen,[...]. Mol Cell Biol 2012
Halfdan Beck, Viola Nähse-Kumpf, Marie Sofie Yoo Larsen, Karen A O'Hanlon, Sebastian Patzke, Christian Holmberg, Jakob Mejlvang, Anja Groth, Olaf Nielsen, Randi G Syljuåsen,[...]. Mol Cell Biol 2012
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ATR and ATRIP: partners in checkpoint signaling.
D Cortez, S Guntuku, J Qin, S J Elledge. Science 2001
D Cortez, S Guntuku, J Qin, S J Elledge. Science 2001
13
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease.
Raquel Domínguez-Kelly, Yusé Martín, Stephane Koundrioukoff, Marvin E Tanenbaum, Veronique A J Smits, René H Medema, Michelle Debatisse, Raimundo Freire. J Cell Biol 2011
Raquel Domínguez-Kelly, Yusé Martín, Stephane Koundrioukoff, Marvin E Tanenbaum, Veronique A J Smits, René H Medema, Michelle Debatisse, Raimundo Freire. J Cell Biol 2011
13
Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells.
Ralph Zellweger, Damian Dalcher, Karun Mutreja, Matteo Berti, Jonas A Schmid, Raquel Herrador, Alessandro Vindigni, Massimo Lopes. J Cell Biol 2015
Ralph Zellweger, Damian Dalcher, Karun Mutreja, Matteo Berti, Jonas A Schmid, Raquel Herrador, Alessandro Vindigni, Massimo Lopes. J Cell Biol 2015
13
The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability.
Huzefa Dungrawala, Kristie L Rose, Kamakoti P Bhat, Kareem N Mohni, Gloria G Glick, Frank B Couch, David Cortez. Mol Cell 2015
Huzefa Dungrawala, Kristie L Rose, Kamakoti P Bhat, Kareem N Mohni, Gloria G Glick, Frank B Couch, David Cortez. Mol Cell 2015
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.