Nadiya Kazachkova, Amanda Ramos, Cristina Santos, Manuela Lima. Aging Dis 2013
Times Cited: 41
Times Cited: 41
Times Cited
Times Co-cited
Similarity
Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
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14
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
14
Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage.
Scott R Kennedy, Jesse J Salk, Michael W Schmitt, Lawrence A Loeb. PLoS Genet 2013
Scott R Kennedy, Jesse J Salk, Michael W Schmitt, Lawrence A Loeb. PLoS Genet 2013
12
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
Andreas Bender, Kim J Krishnan, Christopher M Morris, Geoffrey A Taylor, Amy K Reeve, Robert H Perry, Evelyn Jaros, Joshua S Hersheson, Joanne Betts, Thomas Klopstock,[...]. Nat Genet 2006
Andreas Bender, Kim J Krishnan, Christopher M Morris, Geoffrey A Taylor, Amy K Reeve, Robert H Perry, Evelyn Jaros, Joshua S Hersheson, Joanne Betts, Thomas Klopstock,[...]. Nat Genet 2006
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12
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.
Yevgenya Kraytsberg, Elena Kudryavtseva, Ann C McKee, Changiz Geula, Neil W Kowall, Konstantin Khrapko. Nat Genet 2006
Yevgenya Kraytsberg, Elena Kudryavtseva, Ann C McKee, Changiz Geula, Neil W Kowall, Konstantin Khrapko. Nat Genet 2006
12
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA.
Christian Kukat, Christian A Wurm, Henrik Spåhr, Maria Falkenberg, Nils-Göran Larsson, Stefan Jakobs. Proc Natl Acad Sci U S A 2011
Christian Kukat, Christian A Wurm, Henrik Spåhr, Maria Falkenberg, Nils-Göran Larsson, Stefan Jakobs. Proc Natl Acad Sci U S A 2011
12
Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations.
Leslie S Itsara, Scott R Kennedy, Edward J Fox, Selina Yu, Joshua J Hewitt, Monica Sanchez-Contreras, Fernando Cardozo-Pelaez, Leo J Pallanck. PLoS Genet 2014
Leslie S Itsara, Scott R Kennedy, Edward J Fox, Selina Yu, Joshua J Hewitt, Monica Sanchez-Contreras, Fernando Cardozo-Pelaez, Leo J Pallanck. PLoS Genet 2014
12
The role of mitochondrial DNA mutations and free radicals in disease and ageing.
M Lagouge, N-G Larsson. J Intern Med 2013
M Lagouge, N-G Larsson. J Intern Med 2013
12
Quantitative change in mitochondrial DNA content in various mouse tissues during aging.
Mika Masuyama, Reiko Iida, Hisakazu Takatsuka, Toshihiro Yasuda, Takasumi Matsuki. Biochim Biophys Acta 2005
Mika Masuyama, Reiko Iida, Hisakazu Takatsuka, Toshihiro Yasuda, Takasumi Matsuki. Biochim Biophys Acta 2005
9
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
Adam Ameur, James B Stewart, Christoph Freyer, Erik Hagström, Max Ingman, Nils-Göran Larsson, Ulf Gyllensten. PLoS Genet 2011
Adam Ameur, James B Stewart, Christoph Freyer, Erik Hagström, Max Ingman, Nils-Göran Larsson, Ulf Gyllensten. PLoS Genet 2011
9
Mitochondrial point mutations do not limit the natural lifespan of mice.
Marc Vermulst, Jason H Bielas, Gregory C Kujoth, Warren C Ladiges, Peter S Rabinovitch, Tomas A Prolla, Lawrence A Loeb. Nat Genet 2007
Marc Vermulst, Jason H Bielas, Gregory C Kujoth, Warren C Ladiges, Peter S Rabinovitch, Tomas A Prolla, Lawrence A Loeb. Nat Genet 2007
9
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging.
G C Kujoth, A Hiona, T D Pugh, S Someya, K Panzer, S E Wohlgemuth, T Hofer, A Y Seo, R Sullivan, W A Jobling,[...]. Science 2005
G C Kujoth, A Hiona, T D Pugh, S Someya, K Panzer, S E Wohlgemuth, T Hofer, A Y Seo, R Sullivan, W A Jobling,[...]. Science 2005
9
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.
Aleksandra Trifunovic, Anna Hansson, Anna Wredenberg, Anja T Rovio, Eric Dufour, Ivan Khvorostov, Johannes N Spelbrink, Rolf Wibom, Howard T Jacobs, Nils-Göran Larsson. Proc Natl Acad Sci U S A 2005
Aleksandra Trifunovic, Anna Hansson, Anna Wredenberg, Anja T Rovio, Eric Dufour, Ivan Khvorostov, Johannes N Spelbrink, Rolf Wibom, Howard T Jacobs, Nils-Göran Larsson. Proc Natl Acad Sci U S A 2005
9
The relationship between leukocyte mitochondrial DNA copy number and telomere length in community-dwelling elderly women.
Jung-Ha Kim, Hye Kyung Kim, Jae-Hong Ko, Hyoweon Bang, Duk-Chul Lee. PLoS One 2013
Jung-Ha Kim, Hye Kyung Kim, Jae-Hong Ko, Hyoweon Bang, Duk-Chul Lee. PLoS One 2013
9
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.
G A Cortopassi, D Shibata, N W Soong, N Arnheim. Proc Natl Acad Sci U S A 1992
G A Cortopassi, D Shibata, N W Soong, N Arnheim. Proc Natl Acad Sci U S A 1992
9
Human mitochondrial DNA: roles of inherited and somatic mutations.
Eric A Schon, Salvatore DiMauro, Michio Hirano. Nat Rev Genet 2012
Eric A Schon, Salvatore DiMauro, Michio Hirano. Nat Rev Genet 2012
9
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.
N G Larsson, J Wang, H Wilhelmsson, A Oldfors, P Rustin, M Lewandoski, G S Barsh, D A Clayton. Nat Genet 1998
N G Larsson, J Wang, H Wilhelmsson, A Oldfors, P Rustin, M Lewandoski, G S Barsh, D A Clayton. Nat Genet 1998
9
Extending life span by increasing oxidative stress.
Michael Ristow, Sebastian Schmeisser. Free Radic Biol Med 2011
Michael Ristow, Sebastian Schmeisser. Free Radic Biol Med 2011
7
7
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis.
Feng Li, Yunyue Wang, Karen I Zeller, James J Potter, Diane R Wonsey, Kathryn A O'Donnell, Jung-Whan Kim, Jason T Yustein, Linda A Lee, Chi V Dang. Mol Cell Biol 2005
Feng Li, Yunyue Wang, Karen I Zeller, James J Potter, Diane R Wonsey, Kathryn A O'Donnell, Jung-Whan Kim, Jason T Yustein, Linda A Lee, Chi V Dang. Mol Cell Biol 2005
7
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Ana P Gomes, Nathan L Price, Alvin J Y Ling, Javid J Moslehi, Magdalene K Montgomery, Luis Rajman, James P White, João S Teodoro, Christiane D Wrann, Basil P Hubbard,[...]. Cell 2013
Ana P Gomes, Nathan L Price, Alvin J Y Ling, Javid J Moslehi, Magdalene K Montgomery, Luis Rajman, James P White, João S Teodoro, Christiane D Wrann, Basil P Hubbard,[...]. Cell 2013
7
Mitochondrial threshold effects.
Rodrigue Rossignol, Benjamin Faustin, Christophe Rocher, Monique Malgat, Jean-Pierre Mazat, Thierry Letellier. Biochem J 2003
Rodrigue Rossignol, Benjamin Faustin, Christophe Rocher, Monique Malgat, Jean-Pierre Mazat, Thierry Letellier. Biochem J 2003
7
Normal oxidative damage to mitochondrial and nuclear DNA is extensive.
C Richter, J W Park, B N Ames. Proc Natl Acad Sci U S A 1988
C Richter, J W Park, B N Ames. Proc Natl Acad Sci U S A 1988
7
Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers.
Entela Bua, Jody Johnson, Allen Herbst, Bridget Delong, Debbie McKenzie, Shahriar Salamat, Judd M Aiken. Am J Hum Genet 2006
Entela Bua, Jody Johnson, Allen Herbst, Bridget Delong, Debbie McKenzie, Shahriar Salamat, Judd M Aiken. Am J Hum Genet 2006
7
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.
Marc Vermulst, Jonathan Wanagat, Gregory C Kujoth, Jason H Bielas, Peter S Rabinovitch, Tomas A Prolla, Lawrence A Loeb. Nat Genet 2008
Marc Vermulst, Jonathan Wanagat, Gregory C Kujoth, Jason H Bielas, Peter S Rabinovitch, Tomas A Prolla, Lawrence A Loeb. Nat Genet 2008
7
Is the oxidative stress theory of aging dead?
Viviana I Pérez, Alex Bokov, Holly Van Remmen, James Mele, Qitao Ran, Yuji Ikeno, Arlan Richardson. Biochim Biophys Acta 2009
Viviana I Pérez, Alex Bokov, Holly Van Remmen, James Mele, Qitao Ran, Yuji Ikeno, Arlan Richardson. Biochim Biophys Acta 2009
7
Germline mitochondrial DNA mutations aggravate ageing and can impair brain development.
Jaime M Ross, James B Stewart, Erik Hagström, Stefan Brené, Arnaud Mourier, Giuseppe Coppotelli, Christoph Freyer, Marie Lagouge, Barry J Hoffer, Lars Olson,[...]. Nature 2013
Jaime M Ross, James B Stewart, Erik Hagström, Stefan Brené, Arnaud Mourier, Giuseppe Coppotelli, Christoph Freyer, Marie Lagouge, Barry J Hoffer, Lars Olson,[...]. Nature 2013
7
7
Precise determination of mitochondrial DNA copy number in human skeletal and cardiac muscle by a PCR-based assay: lack of change of copy number with age.
Francis J Miller, Franklin L Rosenfeldt, Chunfang Zhang, Anthony W Linnane, Phillip Nagley. Nucleic Acids Res 2003
Francis J Miller, Franklin L Rosenfeldt, Chunfang Zhang, Anthony W Linnane, Phillip Nagley. Nucleic Acids Res 2003
7
Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner.
Magdalena Frank, Stéphane Duvezin-Caubet, Sebastian Koob, Angelo Occhipinti, Ravi Jagasia, Anton Petcherski, Mika O Ruonala, Muriel Priault, Bénédicte Salin, Andreas S Reichert. Biochim Biophys Acta 2012
Magdalena Frank, Stéphane Duvezin-Caubet, Sebastian Koob, Angelo Occhipinti, Ravi Jagasia, Anton Petcherski, Mika O Ruonala, Muriel Priault, Bénédicte Salin, Andreas S Reichert. Biochim Biophys Acta 2012
7
Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice.
Adeel Safdar, Jacqueline M Bourgeois, Daniel I Ogborn, Jonathan P Little, Bart P Hettinga, Mahmood Akhtar, James E Thompson, Simon Melov, Nicholas J Mocellin, Gregory C Kujoth,[...]. Proc Natl Acad Sci U S A 2011
Adeel Safdar, Jacqueline M Bourgeois, Daniel I Ogborn, Jonathan P Little, Bart P Hettinga, Mahmood Akhtar, James E Thompson, Simon Melov, Nicholas J Mocellin, Gregory C Kujoth,[...]. Proc Natl Acad Sci U S A 2011
7
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals.
G Barja, A Herrero. FASEB J 2000
G Barja, A Herrero. FASEB J 2000
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Number matters: control of mammalian mitochondrial DNA copy number.
Laura L Clay Montier, Janice J Deng, Yidong Bai. J Genet Genomics 2009
Laura L Clay Montier, Janice J Deng, Yidong Bai. J Genet Genomics 2009
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Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing.
J M Cooper, V M Mann, A H Schapira. J Neurol Sci 1992
J M Cooper, V M Mann, A H Schapira. J Neurol Sci 1992
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Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging.
Yau-Huei Wei, Hsin-Chen Lee. Exp Biol Med (Maywood) 2002
Yau-Huei Wei, Hsin-Chen Lee. Exp Biol Med (Maywood) 2002
7
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress.
F M Yakes, B Van Houten. Proc Natl Acad Sci U S A 1997
F M Yakes, B Van Houten. Proc Natl Acad Sci U S A 1997
7
In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice.
Angela Logan, Irina G Shabalina, Tracy A Prime, Sebastian Rogatti, Anastasia V Kalinovich, Richard C Hartley, Ralph C Budd, Barbara Cannon, Michael P Murphy. Aging Cell 2014
Angela Logan, Irina G Shabalina, Tracy A Prime, Sebastian Rogatti, Anastasia V Kalinovich, Richard C Hartley, Ralph C Budd, Barbara Cannon, Michael P Murphy. Aging Cell 2014
7
Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice.
Daniel Edgar, Irina Shabalina, Yolanda Camara, Anna Wredenberg, Maria Antonietta Calvaruso, Leo Nijtmans, Jan Nedergaard, Barbara Cannon, Nils-Göran Larsson, Aleksandra Trifunovic. Cell Metab 2009
Daniel Edgar, Irina Shabalina, Yolanda Camara, Anna Wredenberg, Maria Antonietta Calvaruso, Leo Nijtmans, Jan Nedergaard, Barbara Cannon, Nils-Göran Larsson, Aleksandra Trifunovic. Cell Metab 2009
7
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
G A Cortopassi, N Arnheim. Nucleic Acids Res 1990
G A Cortopassi, N Arnheim. Nucleic Acids Res 1990
7
Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging.
Gudmundur L Norddahl, Cornelis J Pronk, Martin Wahlestedt, Gerd Sten, Jens M Nygren, Amol Ugale, Mikael Sigvardsson, David Bryder. Cell Stem Cell 2011
Gudmundur L Norddahl, Cornelis J Pronk, Martin Wahlestedt, Gerd Sten, Jens M Nygren, Amol Ugale, Mikael Sigvardsson, David Bryder. Cell Stem Cell 2011
7
Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid.
Christian Kukat, Karen M Davies, Christian A Wurm, Henrik Spåhr, Nina A Bonekamp, Inge Kühl, Friederike Joos, Paola Loguercio Polosa, Chan Bae Park, Viktor Posse,[...]. Proc Natl Acad Sci U S A 2015
Christian Kukat, Karen M Davies, Christian A Wurm, Henrik Spåhr, Nina A Bonekamp, Inge Kühl, Friederike Joos, Paola Loguercio Polosa, Chan Bae Park, Viktor Posse,[...]. Proc Natl Acad Sci U S A 2015
7
Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons.
Hirokazu Fukui, Carlos T Moraes. Hum Mol Genet 2009
Hirokazu Fukui, Carlos T Moraes. Hum Mol Genet 2009
7
The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease.
James B Stewart, Patrick F Chinnery. Nat Rev Genet 2015
James B Stewart, Patrick F Chinnery. Nat Rev Genet 2015
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.