Igor Dikiy, David Eliezer. J Biol Chem 2014
Times Cited: 116
Times Cited: 116
Times Cited
Times Co-cited
Similarity
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease.
John P Anderson, Donald E Walker, Jason M Goldstein, Rian de Laat, Kelly Banducci, Russell J Caccavello, Robin Barbour, Jiping Huang, Kristin Kling, Michael Lee,[...]. J Biol Chem 2006
John P Anderson, Donald E Walker, Jason M Goldstein, Rian de Laat, Kelly Banducci, Russell J Caccavello, Robin Barbour, Jiping Huang, Kristin Kling, Michael Lee,[...]. J Biol Chem 2006
37
Impact of N-terminal acetylation of α-synuclein on its random coil and lipid binding properties.
Alexander S Maltsev, Jinfa Ying, Ad Bax. Biochemistry 2012
Alexander S Maltsev, Jinfa Ying, Ad Bax. Biochemistry 2012
36
N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer.
Lijuan Kang, Gina M Moriarty, Lucy A Woods, Alison E Ashcroft, Sheena E Radford, Jean Baum. Protein Sci 2012
Lijuan Kang, Gina M Moriarty, Lucy A Woods, Alison E Ashcroft, Sheena E Radford, Jean Baum. Protein Sci 2012
33
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans.
Thomas Arnesen, Petra Van Damme, Bogdan Polevoda, Kenny Helsens, Rune Evjenth, Niklaas Colaert, Jan Erik Varhaug, Joël Vandekerckhove, Johan R Lillehaug, Fred Sherman,[...]. Proc Natl Acad Sci U S A 2009
Thomas Arnesen, Petra Van Damme, Bogdan Polevoda, Kenny Helsens, Rune Evjenth, Niklaas Colaert, Jan Erik Varhaug, Joël Vandekerckhove, Johan R Lillehaug, Fred Sherman,[...]. Proc Natl Acad Sci U S A 2009
33
α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation.
Tim Bartels, Joanna G Choi, Dennis J Selkoe. Nature 2011
Tim Bartels, Joanna G Choi, Dennis J Selkoe. Nature 2011
32
Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein.
Bruno Fauvet, Mohamed-Bilal Fares, Filsy Samuel, Igor Dikiy, Anurag Tandon, David Eliezer, Hilal A Lashuel. J Biol Chem 2012
Bruno Fauvet, Mohamed-Bilal Fares, Filsy Samuel, Igor Dikiy, Anurag Tandon, David Eliezer, Hilal A Lashuel. J Biol Chem 2012
29
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.
Jacqueline Burré, Manu Sharma, Theodoros Tsetsenis, Vladimir Buchman, Mark R Etherton, Thomas C Südhof. Science 2010
Jacqueline Burré, Manu Sharma, Theodoros Tsetsenis, Vladimir Buchman, Mark R Etherton, Thomas C Südhof. Science 2010
28
N-alpha-acetylation of α-synuclein increases its helical folding propensity, GM1 binding specificity and resistance to aggregation.
Tim Bartels, Nora C Kim, Eric S Luth, Dennis J Selkoe. PLoS One 2014
Tim Bartels, Nora C Kim, Eric S Luth, Dennis J Selkoe. PLoS One 2014
26
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Daniel C Scott, Julie K Monda, Eric J Bennett, J Wade Harper, Brenda A Schulman. Science 2011
Daniel C Scott, Julie K Monda, Eric J Bennett, J Wade Harper, Brenda A Schulman. Science 2011
25
Conformational properties of alpha-synuclein in its free and lipid-associated states.
D Eliezer, E Kutluay, R Bussell, G Browne. J Mol Biol 2001
D Eliezer, E Kutluay, R Bussell, G Browne. J Mol Biol 2001
25
Structural disorder of monomeric α-synuclein persists in mammalian cells.
Francois-Xavier Theillet, Andres Binolfi, Beata Bekei, Andrea Martorana, Honor May Rose, Marchel Stuiver, Silvia Verzini, Dorothea Lorenz, Marleen van Rossum, Daniella Goldfarb,[...]. Nature 2016
Francois-Xavier Theillet, Andres Binolfi, Beata Bekei, Andrea Martorana, Honor May Rose, Marchel Stuiver, Silvia Verzini, Dorothea Lorenz, Marleen van Rossum, Daniella Goldfarb,[...]. Nature 2016
25
First Things First: Vital Protein Marks by N-Terminal Acetyltransferases.
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
24
Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
23
N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
22
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex.
Glen Liszczak, Jacob M Goldberg, Håvard Foyn, E James Petersson, Thomas Arnesen, Ronen Marmorstein. Nat Struct Mol Biol 2013
Glen Liszczak, Jacob M Goldberg, Håvard Foyn, E James Petersson, Thomas Arnesen, Ronen Marmorstein. Nat Struct Mol Biol 2013
22
N-Terminal acetylation is critical for forming α-helical oligomer of α-synuclein.
Adam J Trexler, Elizabeth Rhoades. Protein Sci 2012
Adam J Trexler, Elizabeth Rhoades. Protein Sci 2012
21
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes.
W S Davidson, A Jonas, D F Clayton, J M George. J Biol Chem 1998
W S Davidson, A Jonas, D F Clayton, J M George. J Biol Chem 1998
21
Alpha-synuclein in Lewy bodies.
M G Spillantini, M L Schmidt, V M Lee, J Q Trojanowski, R Jakes, M Goedert. Nature 1997
M G Spillantini, M L Schmidt, V M Lee, J Q Trojanowski, R Jakes, M Goedert. Nature 1997
21
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
21
Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding.
William M Holmes, Brian K Mannakee, Ryan N Gutenkunst, Tricia R Serio. Nat Commun 2014
William M Holmes, Brian K Mannakee, Ryan N Gutenkunst, Tricia R Serio. Nat Commun 2014
28
Structure and dynamics of micelle-bound human alpha-synuclein.
Tobias S Ulmer, Ad Bax, Nelson B Cole, Robert L Nussbaum. J Biol Chem 2005
Tobias S Ulmer, Ad Bax, Nelson B Cole, Robert L Nussbaum. J Biol Chem 2005
20
Multiple tight phospholipid-binding modes of alpha-synuclein revealed by solution NMR spectroscopy.
Christina R Bodner, Christopher M Dobson, Ad Bax. J Mol Biol 2009
Christina R Bodner, Christopher M Dobson, Ad Bax. J Mol Biol 2009
20
The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides.
Matthias Gautschi, Sören Just, Andrej Mun, Suzanne Ross, Peter Rücknagel, Yves Dubaquié, Ann Ehrenhofer-Murray, Sabine Rospert. Mol Cell Biol 2003
Matthias Gautschi, Sören Just, Andrej Mun, Suzanne Ross, Peter Rücknagel, Yves Dubaquié, Ann Ehrenhofer-Murray, Sabine Rospert. Mol Cell Biol 2003
19
Golgi targeting of ARF-like GTPase Arl3p requires its Nalpha-acetylation and the integral membrane protein Sys1p.
Subba Rao Gangi Setty, Todd I Strochlic, Amy Hin Yan Tong, Charles Boone, Christopher G Burd. Nat Cell Biol 2004
Subba Rao Gangi Setty, Todd I Strochlic, Amy Hin Yan Tong, Charles Boone, Christopher G Burd. Nat Cell Biol 2004
19
NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation.
Petra Van Damme, Kristine Hole, Ana Pimenta-Marques, Kenny Helsens, Joël Vandekerckhove, Rui G Martinho, Kris Gevaert, Thomas Arnesen. PLoS Genet 2011
Petra Van Damme, Kristine Hole, Ana Pimenta-Marques, Kenny Helsens, Joël Vandekerckhove, Rui G Martinho, Kris Gevaert, Thomas Arnesen. PLoS Genet 2011
19
Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p.
Rudy Behnia, Bojana Panic, James R C Whyte, Sean Munro. Nat Cell Biol 2004
Rudy Behnia, Bojana Panic, James R C Whyte, Sean Munro. Nat Cell Biol 2004
19
The many faces of α-synuclein: from structure and toxicity to therapeutic target.
Hilal A Lashuel, Cassia R Overk, Abid Oueslati, Eliezer Masliah. Nat Rev Neurosci 2013
Hilal A Lashuel, Cassia R Overk, Abid Oueslati, Eliezer Masliah. Nat Rev Neurosci 2013
18
Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis.
Venu M Nemani, Wei Lu, Victoria Berge, Ken Nakamura, Bibiana Onoa, Michael K Lee, Farrukh A Chaudhry, Roger A Nicoll, Robert H Edwards. Neuron 2010
Venu M Nemani, Wei Lu, Victoria Berge, Ken Nakamura, Bibiana Onoa, Michael K Lee, Farrukh A Chaudhry, Roger A Nicoll, Robert H Edwards. Neuron 2010
17
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia.
Juan J Zarranz, Javier Alegre, Juan C Gómez-Esteban, Elena Lezcano, Raquel Ros, Israel Ampuero, Lídice Vidal, Janet Hoenicka, Olga Rodriguez, Begoña Atarés,[...]. Ann Neurol 2004
Juan J Zarranz, Javier Alegre, Juan C Gómez-Esteban, Elena Lezcano, Raquel Ros, Israel Ampuero, Lídice Vidal, Janet Hoenicka, Olga Rodriguez, Begoña Atarés,[...]. Ann Neurol 2004
17
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions.
Katerina E Paleologou, Abid Oueslati, Gideon Shakked, Carla C Rospigliosi, Hai-Young Kim, Gonzalo R Lamberto, Claudio O Fernandez, Adrian Schmid, Fariba Chegini, Wei Ping Gai,[...]. J Neurosci 2010
Katerina E Paleologou, Abid Oueslati, Gideon Shakked, Carla C Rospigliosi, Hai-Young Kim, Gonzalo R Lamberto, Claudio O Fernandez, Adrian Schmid, Fariba Chegini, Wei Ping Gai,[...]. J Neurosci 2010
17
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
Bruno Fauvet, Martial K Mbefo, Mohamed-Bilal Fares, Carole Desobry, Sarah Michael, Mustafa T Ardah, Elpida Tsika, Philippe Coune, Michel Prudent, Niels Lion,[...]. J Biol Chem 2012
Bruno Fauvet, Martial K Mbefo, Mohamed-Bilal Fares, Carole Desobry, Sarah Michael, Mustafa T Ardah, Elpida Tsika, Philippe Coune, Michel Prudent, Niels Lion,[...]. J Biol Chem 2012
17
An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.
Henriette Aksnes, Petra Van Damme, Marianne Goris, Kristian K Starheim, Michaël Marie, Svein Isungset Støve, Camilla Hoel, Thomas Vikestad Kalvik, Kristine Hole, Nina Glomnes,[...]. Cell Rep 2015
Henriette Aksnes, Petra Van Damme, Marianne Goris, Kristian K Starheim, Michaël Marie, Svein Isungset Støve, Camilla Hoel, Thomas Vikestad Kalvik, Kristine Hole, Nina Glomnes,[...]. Cell Rep 2015
24
The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation.
Thomas Arnesen, Kristian K Starheim, Petra Van Damme, Rune Evjenth, Huyen Dinh, Matthew J Betts, Anita Ryningen, Joël Vandekerckhove, Kris Gevaert, Dave Anderson. Mol Cell Biol 2010
Thomas Arnesen, Kristian K Starheim, Petra Van Damme, Rune Evjenth, Huyen Dinh, Matthew J Betts, Anita Ryningen, Joël Vandekerckhove, Kris Gevaert, Dave Anderson. Mol Cell Biol 2010
19
Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects.
Line M Myklebust, Petra Van Damme, Svein I Støve, Max J Dörfel, Angèle Abboud, Thomas V Kalvik, Cedric Grauffel, Veronique Jonckheere, Yiyang Wu, Jeffrey Swensen,[...]. Hum Mol Genet 2015
Line M Myklebust, Petra Van Damme, Svein I Støve, Max J Dörfel, Angèle Abboud, Thomas V Kalvik, Cedric Grauffel, Veronique Jonckheere, Yiyang Wu, Jeffrey Swensen,[...]. Hum Mol Genet 2015
25
Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency.
Alan F Rope, Kai Wang, Rune Evjenth, Jinchuan Xing, Jennifer J Johnston, Jeffrey J Swensen, W Evan Johnson, Barry Moore, Chad D Huff, Lynne M Bird,[...]. Am J Hum Genet 2011
Alan F Rope, Kai Wang, Rune Evjenth, Jinchuan Xing, Jennifer J Johnston, Jeffrey J Swensen, W Evan Johnson, Barry Moore, Chad D Huff, Lynne M Bird,[...]. Am J Hum Genet 2011
17
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Petra Van Damme, Marta Lasa, Bogdan Polevoda, Cristina Gazquez, Alberto Elosegui-Artola, Duk Soo Kim, Elena De Juan-Pardo, Kimberly Demeyer, Kristine Hole, Esther Larrea,[...]. Proc Natl Acad Sci U S A 2012
Petra Van Damme, Marta Lasa, Bogdan Polevoda, Cristina Gazquez, Alberto Elosegui-Artola, Duk Soo Kim, Elena De Juan-Pardo, Kimberly Demeyer, Kristine Hole, Esther Larrea,[...]. Proc Natl Acad Sci U S A 2012
17
The Impact of N-terminal Acetylation of α-Synuclein on Phospholipid Membrane Binding and Fibril Structure.
Aditya Iyer, Steven J Roeters, Nathalie Schilderink, Bob Hommersom, Ron M A Heeren, Sander Woutersen, Mireille M A E Claessens, Vinod Subramaniam. J Biol Chem 2016
Aditya Iyer, Steven J Roeters, Nathalie Schilderink, Bob Hommersom, Ron M A Heeren, Sander Woutersen, Mireille M A E Claessens, Vinod Subramaniam. J Biol Chem 2016
29
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation.
Céline Galvagnion, Alexander K Buell, Georg Meisl, Thomas C T Michaels, Michele Vendruscolo, Tuomas P J Knowles, Christopher M Dobson. Nat Chem Biol 2015
Céline Galvagnion, Alexander K Buell, Georg Meisl, Thomas C T Michaels, Michele Vendruscolo, Tuomas P J Knowles, Christopher M Dobson. Nat Chem Biol 2015
16
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal.
L Maroteaux, J T Campanelli, R H Scheller. J Neurosci 1988
L Maroteaux, J T Campanelli, R H Scheller. J Neurosci 1988
16
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
R Krüger, W Kuhn, T Müller, D Woitalla, M Graeber, S Kösel, H Przuntek, J T Epplen, L Schöls, O Riess. Nat Genet 1998
R Krüger, W Kuhn, T Müller, D Woitalla, M Graeber, S Kösel, H Przuntek, J T Epplen, L Schöls, O Riess. Nat Genet 1998
16
Protein N-terminal acetyltransferases: when the start matters.
Kristian K Starheim, Kris Gevaert, Thomas Arnesen. Trends Biochem Sci 2012
Kristian K Starheim, Kris Gevaert, Thomas Arnesen. Trends Biochem Sci 2012
16
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour.
Giuliana Fusco, Alfonso De Simone, Tata Gopinath, Vitaly Vostrikov, Michele Vendruscolo, Christopher M Dobson, Gianluigi Veglia. Nat Commun 2014
Giuliana Fusco, Alfonso De Simone, Tata Gopinath, Vitaly Vostrikov, Michele Vendruscolo, Christopher M Dobson, Gianluigi Veglia. Nat Commun 2014
16
Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase.
Petra Van Damme, Rune Evjenth, Håvard Foyn, Kimberly Demeyer, Pieter-Jan De Bock, Johan R Lillehaug, Joël Vandekerckhove, Thomas Arnesen, Kris Gevaert. Mol Cell Proteomics 2011
Petra Van Damme, Rune Evjenth, Håvard Foyn, Kimberly Demeyer, Pieter-Jan De Bock, Johan R Lillehaug, Joël Vandekerckhove, Thomas Arnesen, Kris Gevaert. Mol Cell Proteomics 2011
16
Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation.
Glen Liszczak, Thomas Arnesen, Ronen Marmorstein. J Biol Chem 2011
Glen Liszczak, Thomas Arnesen, Ronen Marmorstein. J Biol Chem 2011
23
alpha-Synuclein is phosphorylated in synucleinopathy lesions.
Hideo Fujiwara, Masato Hasegawa, Naoshi Dohmae, Akiko Kawashima, Eliezer Masliah, Matthew S Goldberg, Jie Shen, Koji Takio, Takeshi Iwatsubo. Nat Cell Biol 2002
Hideo Fujiwara, Masato Hasegawa, Naoshi Dohmae, Akiko Kawashima, Eliezer Masliah, Matthew S Goldberg, Jie Shen, Koji Takio, Takeshi Iwatsubo. Nat Cell Biol 2002
15
A soluble α-synuclein construct forms a dynamic tetramer.
Wei Wang, Iva Perovic, Johnathan Chittuluru, Alice Kaganovich, Linh T T Nguyen, Jingling Liao, Jared R Auclair, Derrick Johnson, Anuradha Landeru, Alana K Simorellis,[...]. Proc Natl Acad Sci U S A 2011
Wei Wang, Iva Perovic, Johnathan Chittuluru, Alice Kaganovich, Linh T T Nguyen, Jingling Liao, Jared R Auclair, Derrick Johnson, Anuradha Landeru, Alana K Simorellis,[...]. Proc Natl Acad Sci U S A 2011
15
alpha-Synuclein locus triplication causes Parkinson's disease.
A B Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum,[...]. Science 2003
A B Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum,[...]. Science 2003
15
N-terminal acetylation inhibits protein targeting to the endoplasmic reticulum.
Gabriella M A Forte, Martin R Pool, Colin J Stirling. PLoS Biol 2011
Gabriella M A Forte, Martin R Pool, Colin J Stirling. PLoS Biol 2011
15
Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.
Thomas Arnesen, Dave Anderson, Christian Baldersheim, Michel Lanotte, Jan E Varhaug, Johan R Lillehaug. Biochem J 2005
Thomas Arnesen, Dave Anderson, Christian Baldersheim, Michel Lanotte, Jan E Varhaug, Johan R Lillehaug. Biochem J 2005
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.