A citation-based method for searching scientific literature

Cendrine Tourette, Biao Li, Russell Bell, Shannon O'Hare, Linda S Kaltenbach, Sean D Mooney, Robert E Hughes. J Biol Chem 2014
Times Cited: 55







List of co-cited articles
629 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Network organization of the huntingtin proteomic interactome in mammalian brain.
Dyna I Shirasaki, Erin R Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A Loo,[...]. Neuron 2012
186
38

Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt,[...]. PLoS Genet 2007
290
29


Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis.
Brady P Culver, Jeffrey N Savas, Sung K Park, Jeong H Choi, Shuqiu Zheng, Scott O Zeitlin, John R Yates, Naoko Tanese. J Biol Chem 2012
85
25

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
409
25


Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
958
20

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
Heike Goehler, Maciej Lalowski, Ulrich Stelzl, Stephanie Waelter, Martin Stroedicke, Uwe Worm, Anja Droege, Katrin S Lindenberg, Maria Knoblich, Christian Haenig,[...]. Mol Cell 2004
316
16

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation.
Jieya Shao, William J Welch, Nicholas A Diprospero, Marc I Diamond. Mol Cell Biol 2008
124
14

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
199
14

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
M Ashburner, C A Ball, J A Blake, D Botstein, H Butler, J M Cherry, A P Davis, K Dolinski, S S Dwight, J T Eppig,[...]. Nat Genet 2000
12

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis.
Tamara Ratovitski, Ekaterine Chighladze, Nicolas Arbez, Tatiana Boronina, Shelley Herbrich, Robert N Cole, Christopher A Ross. Cell Cycle 2012
75
12

Huntingtin as an essential integrator of intracellular vesicular trafficking.
Juliane P Caviston, Erika L F Holzbaur. Trends Cell Biol 2009
177
12

Regional and cellular gene expression changes in human Huntington's disease brain.
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
533
10

A human protein-protein interaction network: a resource for annotating the proteome.
Ulrich Stelzl, Uwe Worm, Maciej Lalowski, Christian Haenig, Felix H Brembeck, Heike Goehler, Martin Stroedicke, Martina Zenkner, Anke Schoenherr, Susanne Koeppen,[...]. Cell 2005
10


Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease.
Lise Munsie, Nicholas Caron, Randy Singh Atwal, Ian Marsden, Edward J Wild, James R Bamburg, Sarah J Tabrizi, Ray Truant. Hum Mol Genet 2011
89
10

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
601
10

Cytoscape: a software environment for integrated models of biomolecular interaction networks.
Paul Shannon, Andrew Markiel, Owen Ozier, Nitin S Baliga, Jonathan T Wang, Daniel Ramage, Nada Amin, Benno Schwikowski, Trey Ideker. Genome Res 2003
9

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.
Sandrine Humbert, Elzbieta A Bryson, Fabrice P Cordelières, Nathan C Connors, Sandeep R Datta, Steven Finkbeiner, Michael E Greenberg, Frédéric Saudou. Dev Cell 2002
363
9

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
9

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
9

Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits.
Spencer U McKinstry, Yonca B Karadeniz, Atesh K Worthington, Volodya Y Hayrapetyan, M Ilcim Ozlu, Karol Serafin-Molina, W Christopher Risher, Tuna Ustunkaya, Ioannis Dragatsis, Scott Zeitlin,[...]. J Neurosci 2014
75
9

Dopamine D2 receptor stimulation potentiates PolyQ-Huntingtin-induced mouse striatal neuron dysfunctions via Rho/ROCK-II activation.
Carole Deyts, Beatriz Galan-Rodriguez, Elodie Martin, Nicolas Bouveyron, Emmanuel Roze, Delphine Charvin, Jocelyne Caboche, Sandrine Bétuing. PLoS One 2009
40
12

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
9


Huntington disease: pathogenesis and treatment.
Praveen Dayalu, Roger L Albin. Neurol Clin 2015
101
9

Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
Juliane P Caviston, Jennifer L Ross, Sheila M Antony, Mariko Tokito, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2007
204
9

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
9

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons.
M DiFiglia, E Sapp, K Chase, C Schwarz, A Meloni, C Young, E Martin, J P Vonsattel, R Carraway, S A Reeves. Neuron 1995
574
9


Huntingtin interacts with a family of WW domain proteins.
P W Faber, G T Barnes, J Srinidhi, J Chen, J F Gusella, M E MacDonald. Hum Mol Genet 1998
306
9

Abeta1-42 stimulates actin polymerization in hippocampal neurons through Rac1 and Cdc42 Rho GTPases.
Ariadna Mendoza-Naranjo, Christian Gonzalez-Billault, Ricardo B Maccioni. J Cell Sci 2007
79
7

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease.
Lars Tönges, Tobias Frank, Lars Tatenhorst, Kim A Saal, Jan C Koch, Éva M Szego, Mathias Bähr, Jochen H Weishaupt, Paul Lingor. Brain 2012
129
7

Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease.
Antonio Valencia, Ellen Sapp, Jeffrey S Kimm, Hollis McClory, Patrick B Reeves, Jonathan Alexander, Kwadwo A Ansong, Nicholas Masso, Matthew P Frosch, Kimberly B Kegel,[...]. Hum Mol Genet 2013
82
7

The beta-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism.
Steven Petratos, Qiao-Xin Li, Amee J George, Xu Hou, Megan L Kerr, Sharon E Unabia, Irene Hatzinisiriou, Danuta Maksel, Marie-Isabel Aguilar, David H Small. Brain 2008
148
7

Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis.
M Takata, H Tanaka, M Kimura, Y Nagahara, K Tanaka, K Kawasaki, M Seto, K Tsuruma, M Shimazawa, H Hara. Br J Pharmacol 2013
78
7

Network medicine: a network-based approach to human disease.
Albert-László Barabási, Natali Gulbahce, Joseph Loscalzo. Nat Rev Genet 2011
7

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing.
D Rigamonti, S Sipione, D Goffredo, C Zuccato, E Fossale, E Cattaneo. J Biol Chem 2001
114
7

Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
569
7

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
7

Huntingtin inhibits caspase-3 activation.
Yu Zhang, Blair R Leavitt, Jeremy M van Raamsdonk, Ioannis Dragatsis, Dan Goldowitz, Marcy E MacDonald, Michael R Hayden, Robert M Friedlander. EMBO J 2006
66
7

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
793
7

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
7

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.
Rona K Graham, Yu Deng, Elizabeth J Slow, Brendan Haigh, Nagat Bissada, Ge Lu, Jacqueline Pearson, Jacqueline Shehadeh, Lisa Bertram, Zoe Murphy,[...]. Cell 2006
472
7

Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus.
Simon C Warby, Crystal N Doty, Rona K Graham, Jeffrey B Carroll, Yu-Zhou Yang, Roshni R Singaraja, Christopher M Overall, Michael R Hayden. Hum Mol Genet 2008
94
7

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
Leslie Michels Thompson, Charity T Aiken, Linda S Kaltenbach, Namita Agrawal, Katalin Illes, Ali Khoshnan, Marta Martinez-Vincente, Montserrat Arrasate, Jacqueline Gire O'Rourke, Hasan Khashwji,[...]. J Cell Biol 2009
259
7

Huntingtin is associated with cytomatrix proteins at the presynaptic terminal.
Jia Yao, Shao-En Ong, Sandra Bajjalieh. Mol Cell Neurosci 2014
13
30


Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
562
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.