Jonathan R Friedman, Jodi Nunnari. Nature 2014
Times Cited: 794
Times Cited: 794
Times Cited
Times Co-cited
Similarity
18
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
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ER tubules mark sites of mitochondrial division.
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Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
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Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.
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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
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Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.
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Mitochondrial fission facilitates the selective mitophagy of protein aggregates.
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Mitochondrial dynamics: overview of molecular mechanisms.
Lisa Tilokani, Shun Nagashima, Vincent Paupe, Julien Prudent. Essays Biochem 2018
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Circulating mitochondrial DAMPs cause inflammatory responses to injury.
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Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
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Mitochondrial fusion and fission in cell life and death.
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The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.
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MiD49 and MiD51, new components of the mitochondrial fission machinery.
Catherine S Palmer, Laura D Osellame, David Laine, Olga S Koutsopoulos, Ann E Frazier, Michael T Ryan. EMBO Rep 2011
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Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain.
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Essential role for Nix in autophagic maturation of erythroid cells.
Hector Sandoval, Perumal Thiagarajan, Swapan K Dasgupta, Armin Schumacher, Josef T Prchal, Min Chen, Jin Wang. Nature 2008
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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology.
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis. Nat Cell Biol 2018
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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations.
Hsiuchen Chen, Marc Vermulst, Yun E Wang, Anne Chomyn, Tomas A Prolla, J Michael McCaffery, David C Chan. Cell 2010
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Mitochondrial dynamics--mitochondrial fission and fusion in human diseases.
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An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2.
Farida Korobova, Vinay Ramabhadran, Henry N Higgs. Science 2013
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A role for myosin II in mammalian mitochondrial fission.
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ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells.
Samantha C Lewis, Lauren F Uchiyama, Jodi Nunnari. Science 2016
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Measuring In Vivo Mitophagy.
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.
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Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites.
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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
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Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy.
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OPA1 requires mitofusin 1 to promote mitochondrial fusion.
Sara Cipolat, Olga Martins de Brito, Barbara Dal Zilio, Luca Scorrano. Proc Natl Acad Sci U S A 2004
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
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Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells.
Hidenori Otera, Chunxin Wang, Megan M Cleland, Kiyoko Setoguchi, Sadaki Yokota, Richard J Youle, Katsuyoshi Mihara. J Cell Biol 2010
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STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism.
Hongxu Xian, Qiaoyun Yang, Lin Xiao, Han-Ming Shen, Yih-Cherng Liou. Nat Commun 2019
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Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.
Catherine S Palmer, Kirstin D Elgass, Robert G Parton, Laura D Osellame, Diana Stojanovski, Michael T Ryan. J Biol Chem 2013
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Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.