Wan Seok Yang, Rohitha SriRamaratnam, Matthew E Welsch, Kenichi Shimada, Rachid Skouta, Vasanthi S Viswanathan, Jaime H Cheah, Paul A Clemons, Alykhan F Shamji, Clary B Clish, Lewis M Brown, Albert W Girotti, Virginia W Cornish, Stuart L Schreiber, Brent R Stockwell. Cell 2014
Times Cited: 1836
Times Cited: 1836
Times Cited
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Similarity
Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
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Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan,[...]. Cell 2017
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan,[...]. Cell 2017
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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Jose Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth, Yulia Y Tyurina, Vladimir A Tyurin, Victoria J Hammond, Nadja Herbach, Michaela Aichler, Axel Walch, Elke Eggenhofer,[...]. Nat Cell Biol 2014
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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.
Valerian E Kagan, Gaowei Mao, Feng Qu, Jose Pedro Friedmann Angeli, Sebastian Doll, Claudette St Croix, Haider Hussain Dar, Bing Liu, Vladimir A Tyurin, Vladimir B Ritov,[...]. Nat Chem Biol 2017
Valerian E Kagan, Gaowei Mao, Feng Qu, Jose Pedro Friedmann Angeli, Sebastian Doll, Claudette St Croix, Haider Hussain Dar, Bing Liu, Vladimir A Tyurin, Vladimir B Ritov,[...]. Nat Chem Biol 2017
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Ferroptosis as a p53-mediated activity during tumour suppression.
Le Jiang, Ning Kon, Tongyuan Li, Shang-Jui Wang, Tao Su, Hanina Hibshoosh, Richard Baer, Wei Gu. Nature 2015
Le Jiang, Ning Kon, Tongyuan Li, Shang-Jui Wang, Tao Su, Hanina Hibshoosh, Richard Baer, Wei Gu. Nature 2015
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FSP1 is a glutathione-independent ferroptosis suppressor.
Sebastian Doll, Florencio Porto Freitas, Ron Shah, Maceler Aldrovandi, Milene Costa da Silva, Irina Ingold, Andrea Goya Grocin, Thamara Nishida Xavier da Silva, Elena Panzilius, Christina H Scheel,[...]. Nature 2019
Sebastian Doll, Florencio Porto Freitas, Ron Shah, Maceler Aldrovandi, Milene Costa da Silva, Irina Ingold, Andrea Goya Grocin, Thamara Nishida Xavier da Silva, Elena Panzilius, Christina H Scheel,[...]. Nature 2019
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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
Sebastian Doll, Bettina Proneth, Yulia Y Tyurina, Elena Panzilius, Sho Kobayashi, Irina Ingold, Martin Irmler, Johannes Beckers, Michaela Aichler, Axel Walch,[...]. Nat Chem Biol 2017
Sebastian Doll, Bettina Proneth, Yulia Y Tyurina, Elena Panzilius, Sho Kobayashi, Irina Ingold, Martin Irmler, Johannes Beckers, Michaela Aichler, Axel Walch,[...]. Nat Chem Biol 2017
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Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells.
Xiaofang Sun, Zhanhui Ou, Ruochan Chen, Xiaohua Niu, De Chen, Rui Kang, Daolin Tang. Hepatology 2016
Xiaofang Sun, Zhanhui Ou, Ruochan Chen, Xiaohua Niu, De Chen, Rui Kang, Daolin Tang. Hepatology 2016
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Ferroptosis: process and function.
Y Xie, W Hou, X Song, Y Yu, J Huang, X Sun, R Kang, D Tang. Cell Death Differ 2016
Y Xie, W Hou, X Song, Y Yu, J Huang, X Sun, R Kang, D Tang. Cell Death Differ 2016
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Ferroptosis: Death by Lipid Peroxidation.
Wan Seok Yang, Brent R Stockwell. Trends Cell Biol 2016
Wan Seok Yang, Brent R Stockwell. Trends Cell Biol 2016
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Autophagy promotes ferroptosis by degradation of ferritin.
Wen Hou, Yangchun Xie, Xinxin Song, Xiaofang Sun, Michael T Lotze, Herbert J Zeh, Rui Kang, Daolin Tang. Autophagy 2016
Wen Hou, Yangchun Xie, Xinxin Song, Xiaofang Sun, Michael T Lotze, Herbert J Zeh, Rui Kang, Daolin Tang. Autophagy 2016
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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Kirill Bersuker, Joseph M Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter H Tang, Melissa A Roberts, Bingqi Tong, Thomas J Maimone, Roberto Zoncu,[...]. Nature 2019
Kirill Bersuker, Joseph M Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter H Tang, Melissa A Roberts, Bingqi Tong, Thomas J Maimone, Roberto Zoncu,[...]. Nature 2019
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Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.
Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher,[...]. Elife 2014
Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher,[...]. Elife 2014
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Glutaminolysis and Transferrin Regulate Ferroptosis.
Minghui Gao, Prashant Monian, Nosirudeen Quadri, Ravichandran Ramasamy, Xuejun Jiang. Mol Cell 2015
Minghui Gao, Prashant Monian, Nosirudeen Quadri, Ravichandran Ramasamy, Xuejun Jiang. Mol Cell 2015
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Ferroptosis: mechanisms, biology and role in disease.
Xuejun Jiang, Brent R Stockwell, Marcus Conrad. Nat Rev Mol Cell Biol 2021
Xuejun Jiang, Brent R Stockwell, Marcus Conrad. Nat Rev Mol Cell Biol 2021
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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.
Irina Ingold, Carsten Berndt, Sabine Schmitt, Sebastian Doll, Gereon Poschmann, Katalin Buday, Antonella Roveri, Xiaoxiao Peng, Florencio Porto Freitas, Tobias Seibt,[...]. Cell 2018
Irina Ingold, Carsten Berndt, Sabine Schmitt, Sebastian Doll, Gereon Poschmann, Katalin Buday, Antonella Roveri, Xiaoxiao Peng, Florencio Porto Freitas, Tobias Seibt,[...]. Cell 2018
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Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.
Wan Seok Yang, Brent R Stockwell. Chem Biol 2008
Wan Seok Yang, Brent R Stockwell. Chem Biol 2008
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FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.
Michael M Gaschler, Alexander A Andia, Hengrui Liu, Joleen M Csuka, Brisa Hurlocker, Christopher A Vaiana, Daniel W Heindel, Dylan S Zuckerman, Pieter H Bos, Eduard Reznik,[...]. Nat Chem Biol 2018
Michael M Gaschler, Alexander A Andia, Hengrui Liu, Joleen M Csuka, Brisa Hurlocker, Christopher A Vaiana, Daniel W Heindel, Dylan S Zuckerman, Pieter H Bos, Eduard Reznik,[...]. Nat Chem Biol 2018
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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.
Vasanthi S Viswanathan, Matthew J Ryan, Harshil D Dhruv, Shubhroz Gill, Ossia M Eichhoff, Brinton Seashore-Ludlow, Samuel D Kaffenberger, John K Eaton, Kenichi Shimada, Andrew J Aguirre,[...]. Nature 2017
Vasanthi S Viswanathan, Matthew J Ryan, Harshil D Dhruv, Shubhroz Gill, Ossia M Eichhoff, Brinton Seashore-Ludlow, Samuel D Kaffenberger, John K Eaton, Kenichi Shimada, Andrew J Aguirre,[...]. Nature 2017
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Ferroptosis as a target for protection against cardiomyopathy.
Xuexian Fang, Hao Wang, Dan Han, Enjun Xie, Xiang Yang, Jiayu Wei, Shanshan Gu, Feng Gao, Nali Zhu, Xiangju Yin,[...]. Proc Natl Acad Sci U S A 2019
Xuexian Fang, Hao Wang, Dan Han, Enjun Xie, Xiang Yang, Jiayu Wei, Shanshan Gu, Feng Gao, Nali Zhu, Xiangju Yin,[...]. Proc Natl Acad Sci U S A 2019
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CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy.
Weimin Wang, Michael Green, Jae Eun Choi, Miguel Gijón, Paul D Kennedy, Jeffrey K Johnson, Peng Liao, Xueting Lang, Ilona Kryczek, Amanda Sell,[...]. Nature 2019
Weimin Wang, Michael Green, Jae Eun Choi, Miguel Gijón, Paul D Kennedy, Jeffrey K Johnson, Peng Liao, Xueting Lang, Ilona Kryczek, Amanda Sell,[...]. Nature 2019
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Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.
Kenichi Shimada, Rachid Skouta, Anna Kaplan, Wan Seok Yang, Miki Hayano, Scott J Dixon, Lewis M Brown, Carlos A Valenzuela, Adam J Wolpaw, Brent R Stockwell. Nat Chem Biol 2016
Kenichi Shimada, Rachid Skouta, Anna Kaplan, Wan Seok Yang, Miki Hayano, Scott J Dixon, Lewis M Brown, Carlos A Valenzuela, Adam J Wolpaw, Brent R Stockwell. Nat Chem Biol 2016
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Recent Progress in Ferroptosis Inducers for Cancer Therapy.
Chen Liang, Xinglin Zhang, Mengsu Yang, Xiaochen Dong. Adv Mater 2019
Chen Liang, Xinglin Zhang, Mengsu Yang, Xiaochen Dong. Adv Mater 2019
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Targeting Ferroptosis to Iron Out Cancer.
Behrouz Hassannia, Peter Vandenabeele, Tom Vanden Berghe. Cancer Cell 2019
Behrouz Hassannia, Peter Vandenabeele, Tom Vanden Berghe. Cancer Cell 2019
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The role of iron and reactive oxygen species in cell death.
Scott J Dixon, Brent R Stockwell. Nat Chem Biol 2014
Scott J Dixon, Brent R Stockwell. Nat Chem Biol 2014
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RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels.
Nicholas Yagoda, Moritz von Rechenberg, Elma Zaganjor, Andras J Bauer, Wan Seok Yang, Daniel J Fridman, Adam J Wolpaw, Inese Smukste, John M Peltier, J Jay Boniface,[...]. Nature 2007
Nicholas Yagoda, Moritz von Rechenberg, Elma Zaganjor, Andras J Bauer, Wan Seok Yang, Daniel J Fridman, Adam J Wolpaw, Inese Smukste, John M Peltier, J Jay Boniface,[...]. Nature 2007
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Role of GPX4 in ferroptosis and its pharmacological implication.
Tobias M Seibt, Bettina Proneth, Marcus Conrad. Free Radic Biol Med 2019
Tobias M Seibt, Bettina Proneth, Marcus Conrad. Free Radic Biol Med 2019
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Ferroptosis, a new form of cell death: opportunities and challenges in cancer.
Yanhua Mou, Jun Wang, Jinchun Wu, Dan He, Chunfang Zhang, Chaojun Duan, Bin Li. J Hematol Oncol 2019
Yanhua Mou, Jun Wang, Jinchun Wu, Dan He, Chunfang Zhang, Chaojun Duan, Bin Li. J Hematol Oncol 2019
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Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells.
Sonam Dolma, Stephen L Lessnick, William C Hahn, Brent R Stockwell. Cancer Cell 2003
Sonam Dolma, Stephen L Lessnick, William C Hahn, Brent R Stockwell. Cancer Cell 2003
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews,[...]. Cell Death Differ 2018
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews,[...]. Cell Death Differ 2018
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Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.
Wan Seok Yang, Katherine J Kim, Michael M Gaschler, Milesh Patel, Mikhail S Shchepinov, Brent R Stockwell. Proc Natl Acad Sci U S A 2016
Wan Seok Yang, Katherine J Kim, Michael M Gaschler, Milesh Patel, Mikhail S Shchepinov, Brent R Stockwell. Proc Natl Acad Sci U S A 2016
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Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death.
Alexander Seiler, Manuela Schneider, Heidi Förster, Stephan Roth, Eva K Wirth, Carsten Culmsee, Nikolaus Plesnila, Elisabeth Kremmer, Olof Rådmark, Wolfgang Wurst,[...]. Cell Metab 2008
Alexander Seiler, Manuela Schneider, Heidi Förster, Stephan Roth, Eva K Wirth, Carsten Culmsee, Nikolaus Plesnila, Elisabeth Kremmer, Olof Rådmark, Wolfgang Wurst,[...]. Cell Metab 2008
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Ferroptosis: past, present and future.
Jie Li, Feng Cao, He-Liang Yin, Zi-Jian Huang, Zhi-Tao Lin, Ning Mao, Bei Sun, Gang Wang. Cell Death Dis 2020
Jie Li, Feng Cao, He-Liang Yin, Zi-Jian Huang, Zhi-Tao Lin, Ning Mao, Bei Sun, Gang Wang. Cell Death Dis 2020
12
Ferroptosis is an autophagic cell death process.
Minghui Gao, Prashant Monian, Qiuhui Pan, Wei Zhang, Jenny Xiang, Xuejun Jiang. Cell Res 2016
Minghui Gao, Prashant Monian, Qiuhui Pan, Wei Zhang, Jenny Xiang, Xuejun Jiang. Cell Res 2016
12
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.
Matthew J Hangauer, Vasanthi S Viswanathan, Matthew J Ryan, Dhruv Bole, John K Eaton, Alexandre Matov, Jacqueline Galeas, Harshil D Dhruv, Michael E Berens, Stuart L Schreiber,[...]. Nature 2017
Matthew J Hangauer, Vasanthi S Viswanathan, Matthew J Ryan, Dhruv Bole, John K Eaton, Alexandre Matov, Jacqueline Galeas, Harshil D Dhruv, Michael E Berens, Stuart L Schreiber,[...]. Nature 2017
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Role of Mitochondria in Ferroptosis.
Minghui Gao, Junmei Yi, Jiajun Zhu, Alexander M Minikes, Prashant Monian, Craig B Thompson, Xuejun Jiang. Mol Cell 2019
Minghui Gao, Junmei Yi, Jiajun Zhu, Alexander M Minikes, Prashant Monian, Craig B Thompson, Xuejun Jiang. Mol Cell 2019
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Energy-stress-mediated AMPK activation inhibits ferroptosis.
Hyemin Lee, Fereshteh Zandkarimi, Yilei Zhang, Jitendra Kumar Meena, Jongchan Kim, Li Zhuang, Siddhartha Tyagi, Li Ma, Thomas F Westbrook, Gregory R Steinberg,[...]. Nat Cell Biol 2020
Hyemin Lee, Fereshteh Zandkarimi, Yilei Zhang, Jitendra Kumar Meena, Jongchan Kim, Li Zhuang, Siddhartha Tyagi, Li Ma, Thomas F Westbrook, Gregory R Steinberg,[...]. Nat Cell Biol 2020
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NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis.
Matthew Dodson, Raul Castro-Portuguez, Donna D Zhang. Redox Biol 2019
Matthew Dodson, Raul Castro-Portuguez, Donna D Zhang. Redox Biol 2019
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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death.
Scott J Dixon, Georg E Winter, Leila S Musavi, Eric D Lee, Berend Snijder, Manuele Rebsamen, Giulio Superti-Furga, Brent R Stockwell. ACS Chem Biol 2015
Scott J Dixon, Georg E Winter, Leila S Musavi, Eric D Lee, Berend Snijder, Manuele Rebsamen, Giulio Superti-Furga, Brent R Stockwell. ACS Chem Biol 2015
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GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling.
Vanessa A N Kraft, Carla T Bezjian, Susanne Pfeiffer, Larissa Ringelstetter, Constanze Müller, Fereshteh Zandkarimi, Juliane Merl-Pham, Xuanwen Bao, Natasa Anastasov, Johanna Kössl,[...]. ACS Cent Sci 2020
Vanessa A N Kraft, Carla T Bezjian, Susanne Pfeiffer, Larissa Ringelstetter, Constanze Müller, Fereshteh Zandkarimi, Juliane Merl-Pham, Xuanwen Bao, Natasa Anastasov, Johanna Kössl,[...]. ACS Cent Sci 2020
10
The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression.
Guang Lei, Yilei Zhang, Pranavi Koppula, Xiaoguang Liu, Jie Zhang, Steven H Lin, Jaffer A Ajani, Qin Xiao, Zhongxing Liao, Hui Wang,[...]. Cell Res 2020
Guang Lei, Yilei Zhang, Pranavi Koppula, Xiaoguang Liu, Jie Zhang, Steven H Lin, Jaffer A Ajani, Qin Xiao, Zhongxing Liao, Hui Wang,[...]. Cell Res 2020
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Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion.
José Pedro Friedmann Angeli, Dmitri V Krysko, Marcus Conrad. Nat Rev Cancer 2019
José Pedro Friedmann Angeli, Dmitri V Krysko, Marcus Conrad. Nat Rev Cancer 2019
10
BAP1 links metabolic regulation of ferroptosis to tumour suppression.
Yilei Zhang, Jiejun Shi, Xiaoguang Liu, Li Feng, Zihua Gong, Pranavi Koppula, Kapil Sirohi, Xu Li, Yongkun Wei, Hyemin Lee,[...]. Nat Cell Biol 2018
Yilei Zhang, Jiejun Shi, Xiaoguang Liu, Li Feng, Zihua Gong, Pranavi Koppula, Kapil Sirohi, Xu Li, Yongkun Wei, Hyemin Lee,[...]. Nat Cell Biol 2018
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Lipid peroxidation and ferroptosis: The role of GSH and GPx4.
Fulvio Ursini, Matilde Maiorino. Free Radic Biol Med 2020
Fulvio Ursini, Matilde Maiorino. Free Radic Biol Med 2020
10
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Broadening horizons: the role of ferroptosis in cancer.
Xin Chen, Rui Kang, Guido Kroemer, Daolin Tang. Nat Rev Clin Oncol 2021
Xin Chen, Rui Kang, Guido Kroemer, Daolin Tang. Nat Rev Clin Oncol 2021
10
Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Michael A Badgley, Daniel M Kremer, H Carlo Maurer, Kathleen E DelGiorno, Ho-Joon Lee, Vinee Purohit, Irina R Sagalovskiy, Alice Ma, Jonathan Kapilian, Christina E M Firl,[...]. Science 2020
Michael A Badgley, Daniel M Kremer, H Carlo Maurer, Kathleen E DelGiorno, Ho-Joon Lee, Vinee Purohit, Irina R Sagalovskiy, Alice Ma, Jonathan Kapilian, Christina E M Firl,[...]. Science 2020
10
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.
Chao Mao, Xiaoguang Liu, Yilei Zhang, Guang Lei, Yuelong Yan, Hyemin Lee, Pranavi Koppula, Shiqi Wu, Li Zhuang, Bingliang Fang,[...]. Nature 2021
Chao Mao, Xiaoguang Liu, Yilei Zhang, Guang Lei, Yuelong Yan, Hyemin Lee, Pranavi Koppula, Shiqi Wu, Li Zhuang, Bingliang Fang,[...]. Nature 2021
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GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis.
Giovanni C Forcina, Scott J Dixon. Proteomics 2019
Giovanni C Forcina, Scott J Dixon. Proteomics 2019
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.