Yanfang Fu, Jeffry D Sander, Deepak Reyon, Vincent M Cascio, J Keith Joung. Nat Biotechnol 2014
Times Cited: 1168
Times Cited: 1168
Times Cited
Times Co-cited
Similarity
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Multiplex genome engineering using CRISPR/Cas systems.
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Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
37
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Search-and-replace genome editing without double-strand breaks or donor DNA.
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DNA targeting specificity of RNA-guided Cas9 nucleases.
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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
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Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
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CRISPR provides acquired resistance against viruses in prokaryotes.
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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins.
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In vivo genome editing using Staphylococcus aureus Cas9.
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
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Crystal structure of Cas9 in complex with guide RNA and target DNA.
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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
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Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
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Improving CRISPR-Cas specificity with chemical modifications in single-guide RNAs.
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Increasing the specificity of CRISPR systems with engineered RNA secondary structures.
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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.
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Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
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Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.
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Genome engineering using the CRISPR-Cas9 system.
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Genetic screens in human cells using the CRISPR-Cas9 system.
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16
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
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15
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
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15
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
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14
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
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14
Base editing: precision chemistry on the genome and transcriptome of living cells.
Holly A Rees, David R Liu. Nat Rev Genet 2018
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14
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification.
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14
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells.
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Directed evolution of CRISPR-Cas9 to increase its specificity.
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Development and applications of CRISPR-Cas9 for genome engineering.
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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.
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Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
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12
Identification of preexisting adaptive immunity to Cas9 proteins in humans.
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Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
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12
Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.
Carolin Anders, Ole Niewoehner, Alessia Duerst, Martin Jinek. Nature 2014
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11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.