A citation-based method for searching scientific literature

Yanfang Fu, Jeffry D Sander, Deepak Reyon, Vincent M Cascio, J Keith Joung. Nat Biotechnol 2014
Times Cited: 1168







List of co-cited articles
1244 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
59

Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
44

Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
37

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
36

RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
35

Search-and-replace genome editing without double-strand breaks or donor DNA.
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
31

DNA targeting specificity of RNA-guided Cas9 nucleases.
Patrick D Hsu, David A Scott, Joshua A Weinstein, F Ann Ran, Silvana Konermann, Vineeta Agarwala, Yinqing Li, Eli J Fine, Xuebing Wu, Ophir Shalem,[...]. Nat Biotechnol 2013
31

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
27

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
26

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Bernd Zetsche, Jonathan S Gootenberg, Omar O Abudayyeh, Ian M Slaymaker, Kira S Makarova, Patrick Essletzbichler, Sara E Volz, Julia Joung, John van der Oost, Aviv Regev,[...]. Cell 2015
25

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
Janice S Chen, Yavuz S Dagdas, Benjamin P Kleinstiver, Moira M Welch, Alexander A Sousa, Lucas B Harrington, Samuel H Sternberg, J Keith Joung, Ahmet Yildiz, Jennifer A Doudna. Nature 2017
548
25

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
F Ann Ran, Patrick D Hsu, Chie-Yu Lin, Jonathan S Gootenberg, Silvana Konermann, Alexandro E Trevino, David A Scott, Azusa Inoue, Shogo Matoba, Yi Zhang,[...]. Cell 2013
24

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
24

CRISPR provides acquired resistance against viruses in prokaryotes.
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau, Melissa Richards, Patrick Boyaval, Sylvain Moineau, Dennis A Romero, Philippe Horvath. Science 2007
24

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins.
Sojung Kim, Daesik Kim, Seung Woo Cho, Jungeun Kim, Jin-Soo Kim. Genome Res 2014
956
22

In vivo genome editing using Staphylococcus aureus Cas9.
F Ann Ran, Le Cong, Winston X Yan, David A Scott, Jonathan S Gootenberg, Andrea J Kriz, Bernd Zetsche, Ophir Shalem, Xuebing Wu, Kira S Makarova,[...]. Nature 2015
21

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Johnny H Hu, Shannon M Miller, Maarten H Geurts, Weixin Tang, Liwei Chen, Ning Sun, Christina M Zeina, Xue Gao, Holly A Rees, Zhi Lin,[...]. Nature 2018
708
21

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
Shengdar Q Tsai, Zongli Zheng, Nhu T Nguyen, Matthew Liebers, Ved V Topkar, Vishal Thapar, Nicolas Wyvekens, Cyd Khayter, A John Iafrate, Long P Le,[...]. Nat Biotechnol 2015
21

Crystal structure of Cas9 in complex with guide RNA and target DNA.
Hiroshi Nishimasu, F Ann Ran, Patrick D Hsu, Silvana Konermann, Soraya I Shehata, Naoshi Dohmae, Ryuichiro Ishitani, Feng Zhang, Osamu Nureki. Cell 2014
945
20

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
20

Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Benjamin P Kleinstiver, Michelle S Prew, Shengdar Q Tsai, Ved V Topkar, Nhu T Nguyen, Zongli Zheng, Andrew P W Gonzales, Zhuyun Li, Randall T Peterson, Jing-Ruey Joanna Yeh,[...]. Nature 2015
894
19

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.
Luke A Gilbert, Matthew H Larson, Leonardo Morsut, Zairan Liu, Gloria A Brar, Sandra E Torres, Noam Stern-Ginossar, Onn Brandman, Evan H Whitehead, Jennifer A Doudna,[...]. Cell 2013
19

Improving CRISPR-Cas specificity with chemical modifications in single-guide RNAs.
Daniel E Ryan, David Taussig, Israel Steinfeld, Smruti M Phadnis, Benjamin D Lunstad, Madhurima Singh, Xuan Vuong, Kenji D Okochi, Ryan McCaffrey, Magdalena Olesiak,[...]. Nucleic Acids Res 2018
123
18

Increasing the specificity of CRISPR systems with engineered RNA secondary structures.
D Dewran Kocak, Eric A Josephs, Vidit Bhandarkar, Shaunak S Adkar, Jennifer B Kwon, Charles A Gersbach. Nat Biotechnol 2019
135
18

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
Giedrius Gasiunas, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys. Proc Natl Acad Sci U S A 2012
18

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.
Seung Woo Cho, Sojung Kim, Yongsub Kim, Jiyeon Kweon, Heon Seok Kim, Sangsu Bae, Jin-Soo Kim. Genome Res 2014
851
17

Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
16

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.
Hao Yin, Chun-Qing Song, Sneha Suresh, Suet-Yan Kwan, Qiongqiong Wu, Stephen Walsh, Junmei Ding, Roman L Bogorad, Lihua Julie Zhu, Scot A Wolfe,[...]. Nat Chem Biol 2018
119
16

Genome engineering using the CRISPR-Cas9 system.
F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang. Nat Protoc 2013
16

Genetic screens in human cells using the CRISPR-Cas9 system.
Tim Wang, Jenny J Wei, David M Sabatini, Eric S Lander. Science 2014
16

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
John G Doench, Nicolo Fusi, Meagan Sullender, Mudra Hegde, Emma W Vaimberg, Katherine F Donovan, Ian Smith, Zuzana Tothova, Craig Wilen, Robert Orchard,[...]. Nat Biotechnol 2016
15

A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Antonio Casini, Michele Olivieri, Gianluca Petris, Claudia Montagna, Giordano Reginato, Giulia Maule, Francesca Lorenzin, Davide Prandi, Alessandro Romanel, Francesca Demichelis,[...]. Nat Biotechnol 2018
208
15

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
John G Doench, Ella Hartenian, Daniel B Graham, Zuzana Tothova, Mudra Hegde, Ian Smith, Meagan Sullender, Benjamin L Ebert, Ramnik J Xavier, David E Root. Nat Biotechnol 2014
842
14

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
Hao Yin, Chun-Qing Song, Sneha Suresh, Qiongqiong Wu, Stephen Walsh, Luke Hyunsik Rhym, Esther Mintzer, Mehmet Fatih Bolukbasi, Lihua Julie Zhu, Kevin Kauffman,[...]. Nat Biotechnol 2017
223
14



A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells.
Christopher A Vakulskas, Daniel P Dever, Garrett R Rettig, Rolf Turk, Ashley M Jacobi, Michael A Collingwood, Nicole M Bode, Matthew S McNeill, Shuqi Yan, Joab Camarena,[...]. Nat Med 2018
308
14

Directed evolution of CRISPR-Cas9 to increase its specificity.
Jungjoon K Lee, Euihwan Jeong, Joonsun Lee, Minhee Jung, Eunji Shin, Young-Hoon Kim, Kangin Lee, Inyoung Jung, Daesik Kim, Seokjoong Kim,[...]. Nat Commun 2018
196
14

Development and applications of CRISPR-Cas9 for genome engineering.
Patrick D Hsu, Eric S Lander, Feng Zhang. Cell 2014
14


High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.
Vikram Pattanayak, Steven Lin, John P Guilinger, Enbo Ma, Jennifer A Doudna, David R Liu. Nat Biotechnol 2013
915
13

Off-target Effects in CRISPR/Cas9-mediated Genome Engineering.
Xiao-Hui Zhang, Louis Y Tee, Xiao-Gang Wang, Qun-Shan Huang, Shi-Hua Yang. Mol Ther Nucleic Acids 2015
481
13

Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
Kira S Makarova, Yuri I Wolf, Jaime Iranzo, Sergey A Shmakov, Omer S Alkhnbashi, Stan J J Brouns, Emmanuelle Charpentier, David Cheng, Daniel H Haft, Philippe Horvath,[...]. Nat Rev Microbiol 2020
477
13

Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements.
Francisco J M Mojica, César Díez-Villaseñor, Jesús García-Martínez, Elena Soria. J Mol Evol 2005
13

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III.
Elitza Deltcheva, Krzysztof Chylinski, Cynthia M Sharma, Karine Gonzales, Yanjie Chao, Zaid A Pirzada, Maria R Eckert, Jörg Vogel, Emmanuelle Charpentier. Nature 2011
12


Identification of preexisting adaptive immunity to Cas9 proteins in humans.
Carsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, Joab Camarena, Viktor T Lemgart, M Kyle Cromer, Christopher A Vakulskas, Michael A Collingwood, Liyang Zhang, Nicole M Bode,[...]. Nat Med 2019
356
12

Identification of genes that are associated with DNA repeats in prokaryotes.
Ruud Jansen, Jan D A van Embden, Wim Gaastra, Leo M Schouls. Mol Microbiol 2002
926
12

Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
437
12

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.
Carolin Anders, Ole Niewoehner, Alessia Duerst, Martin Jinek. Nature 2014
662
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.