A citation-based method for searching scientific literature

Karen E Murphy, Amanda M Gysbers, Sarah K Abbott, Nahid Tayebi, Woojin S Kim, Ellen Sidransky, Antony Cooper, Brett Garner, Glenda M Halliday. Brain 2014
Times Cited: 324







List of co-cited articles
1750 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies.
Joseph R Mazzulli, You-Hai Xu, Ying Sun, Adam L Knight, Pamela J McLean, Guy A Caldwell, Ellen Sidransky, Gregory A Grabowski, Dimitri Krainc. Cell 2011
887
51

Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains.
Matthew E Gegg, Derek Burke, Simon J R Heales, J Mark Cooper, John Hardy, Nicholas W Wood, Anthony H V Schapira. Ann Neurol 2012
383
51

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.
E Sidransky, M A Nalls, J O Aasly, J Aharon-Peretz, G Annesi, E R Barbosa, A Bar-Shira, D Berg, J Bras, A Brice,[...]. N Engl J Med 2009
49

Glucocerebrosidase activity in Parkinson's disease with and without GBA mutations.
Roy N Alcalay, Oren A Levy, Cheryl C Waters, Stanley Fahn, Blair Ford, Sheng-Han Kuo, Pietro Mazzoni, Michael W Pauciulo, William C Nichols, Ziv Gan-Or,[...]. Brain 2015
233
33

iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis.
David C Schöndorf, Massimo Aureli, Fiona E McAllister, Christopher J Hindley, Florian Mayer, Benjamin Schmid, S Pablo Sardi, Manuela Valsecchi, Susanna Hoffmann, Lukas Kristoffer Schwarz,[...]. Nat Commun 2014
331
23

Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies.
Davide Chiasserini, Silvia Paciotti, Paolo Eusebi, Emanuele Persichetti, Anna Tasegian, Marzena Kurzawa-Akanbi, Patrick F Chinnery, Christopher M Morris, Paolo Calabresi, Lucilla Parnetti,[...]. Mol Neurodegener 2015
95
23

Alpha-synuclein in Lewy bodies.
M G Spillantini, M L Schmidt, V M Lee, J Q Trojanowski, R Jakes, M Goedert. Nature 1997
22

CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy.
S Pablo Sardi, Jennifer Clarke, Cathrine Kinnecom, Thomas J Tamsett, Lingyun Li, Lisa M Stanek, Marco A Passini, Gregory A Grabowski, Michael G Schlossmacher, Richard L Sidman,[...]. Proc Natl Acad Sci U S A 2011
222
22

Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease.
Yumiko V Taguchi, Jun Liu, Jiapeng Ruan, Joshua Pacheco, Xiaokui Zhang, Justin Abbasi, Joan Keutzer, Pramod K Mistry, Sreeganga S Chandra. J Neurosci 2017
127
21

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease.
Juliane Neumann, Jose Bras, Emma Deas, Sean S O'Sullivan, Laura Parkkinen, Robin H Lachmann, Abi Li, Janice Holton, Rita Guerreiro, Reema Paudel,[...]. Brain 2009
460
21

Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations: A Nonrandomized, Noncontrolled Trial.
Stephen Mullin, Laura Smith, Katherine Lee, Gayle D'Souza, Philip Woodgate, Josh Elflein, Jenny Hällqvist, Marco Toffoli, Adam Streeter, Joanne Hosking,[...]. JAMA Neurol 2020
130
20

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
Ana Maria Cuervo, Leonidas Stefanis, Ross Fredenburg, Peter T Lansbury, David Sulzer. Science 2004
19

Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide.
Friederike Zunke, Alexandra C Moise, Nandkishore R Belur, Eilrayna Gelyana, Iva Stojkovska, Haris Dzaferbegovic, Nicholas J Toker, Sohee Jeon, Kristina Fredriksen, Joseph R Mazzulli. Neuron 2018
125
19

Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice.
Anna Migdalska-Richards, Liam Daly, Erwan Bezard, Anthony H V Schapira. Ann Neurol 2016
114
18

Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.
Joseph R Mazzulli, Friederike Zunke, Taiji Tsunemi, Nicholas J Toker, Sohee Jeon, Lena F Burbulla, Samarjit Patnaik, Ellen Sidransky, Juan J Marugan, Carolyn M Sue,[...]. J Neurosci 2016
162
18

Progressive decline of glucocerebrosidase in aging and Parkinson's disease.
Emily M Rocha, Gaynor A Smith, Eric Park, Hongmei Cao, Eilish Brown, Penelope Hallett, Ole Isacson. Ann Clin Transl Neurol 2015
124
18

Survival and dementia in GBA-associated Parkinson's disease: The mutation matters.
Roberto Cilia, Sara Tunesi, Giorgio Marotta, Emanuele Cereda, Chiara Siri, Silvana Tesei, Anna L Zecchinelli, Margherita Canesi, Claudio B Mariani, Nicoletta Meucci,[...]. Ann Neurol 2016
205
18

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.
S Pablo Sardi, Catherine Viel, Jennifer Clarke, Christopher M Treleaven, Amy M Richards, Hyejung Park, Maureen A Olszewski, James C Dodge, John Marshall, Elina Makino,[...]. Proc Natl Acad Sci U S A 2017
121
17

No evidence for substrate accumulation in Parkinson brains with GBA mutations.
Matthew E Gegg, Lindsay Sweet, Bing H Wang, Lamya S Shihabuddin, Sergio Pablo Sardi, Anthony H V Schapira. Mov Disord 2015
94
18

Chaperone-mediated autophagy markers in Parkinson disease brains.
Lydia Alvarez-Erviti, Maria C Rodriguez-Oroz, J Mark Cooper, Cristina Caballero, Isidro Ferrer, Jose A Obeso, Anthony H V Schapira. Arch Neurol 2010
352
17

Staging of brain pathology related to sporadic Parkinson's disease.
Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak. Neurobiol Aging 2003
17

A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies.
Michael A Nalls, Raquel Duran, Grisel Lopez, Marzena Kurzawa-Akanbi, Ian G McKeith, Patrick F Chinnery, Christopher M Morris, Jessie Theuns, David Crosiers, Patrick Cras,[...]. JAMA Neurol 2013
273
17

Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA).
Kathleen S Hruska, Mary E LaMarca, C Ronald Scott, Ellen Sidransky. Hum Mutat 2008
408
17

Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson's Disease and Dementia with Lewy Bodies.
Tim E Moors, Silvia Paciotti, Angela Ingrassia, Marialuisa Quadri, Guido Breedveld, Anna Tasegian, Davide Chiasserini, Paolo Eusebi, Gonzalo Duran-Pacheco, Thomas Kremer,[...]. Mol Neurobiol 2019
69
23

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.
Hugo J R Fernandes, Elizabeth M Hartfield, Helen C Christian, Evangelia Emmanoulidou, Ying Zheng, Heather Booth, Helle Bogetofte, Charmaine Lang, Brent J Ryan, S Pablo Sardi,[...]. Stem Cell Reports 2016
200
16

The link between the GBA gene and parkinsonism.
Ellen Sidransky, Grisel Lopez. Lancet Neurol 2012
348
16

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
Mike A Nalls, Nathan Pankratz, Christina M Lill, Chuong B Do, Dena G Hernandez, Mohamad Saad, Anita L DeStefano, Eleanna Kara, Jose Bras, Manu Sharma,[...]. Nat Genet 2014
15

Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models.
Alvaro Sanchez-Martinez, Michelle Beavan, Matthew E Gegg, Kai-Yin Chau, Alexander J Whitworth, Anthony H V Schapira. Sci Rep 2016
94
15

Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies.
S Pablo Sardi, Jennifer Clarke, Catherine Viel, Monyrath Chan, Thomas J Tamsett, Christopher M Treleaven, Jie Bu, Lindsay Sweet, Marco A Passini, James C Dodge,[...]. Proc Natl Acad Sci U S A 2013
165
15

Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease.
Laurie A Robak, Iris E Jansen, Jeroen van Rooij, André G Uitterlinden, Robert Kraaij, Joseph Jankovic, Peter Heutink, Joshua M Shulman. Brain 2017
213
15

Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells.
Alisdair McNeill, Joana Magalhaes, Chengguo Shen, Kai-Yin Chau, Derralyn Hughes, Atul Mehta, Tom Foltynie, J Mark Cooper, Andrey Y Abramov, Matthew Gegg,[...]. Brain 2014
210
15

GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers.
Sangjune Kim, Seung Pil Yun, Saebom Lee, George Essien Umanah, Veera Venkata Ratnam Bandaru, Xiling Yin, Peter Rhee, Senthilkumar S Karuppagounder, Seung-Hwan Kwon, Hojae Lee,[...]. Proc Natl Acad Sci U S A 2018
115
15

Glucocerebrosidase and its relevance to Parkinson disease.
Jenny Do, Cindy McKinney, Pankaj Sharma, Ellen Sidransky. Mol Neurodegener 2019
117
15

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models.
Joseph R Mazzulli, Friederike Zunke, Ole Isacson, Lorenz Studer, Dimitri Krainc. Proc Natl Acad Sci U S A 2016
218
14

Cerebrospinal fluid β-glucocerebrosidase activity is reduced in parkinson's disease patients.
Lucilla Parnetti, Silvia Paciotti, Paolo Eusebi, Andrea Dardis, Stefania Zampieri, Davide Chiasserini, Anna Tasegian, Nicola Tambasco, Bruno Bembi, Paolo Calabresi,[...]. Mov Disord 2017
86
16

Penetrance of Parkinson disease in glucocerebrosidase gene mutation carriers.
M Anheim, A Elbaz, S Lesage, A Durr, C Condroyer, F Viallet, P Pollak, B Bonaïti, C Bonaïti-Pellié, A Brice. Neurology 2012
155
14

A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism.
Elma Aflaki, Daniel K Borger, Nima Moaven, Barbara K Stubblefield, Steven A Rogers, Samarjit Patnaik, Frank J Schoenen, Wendy Westbroek, Wei Zheng, Patricia Sullivan,[...]. J Neurosci 2016
145
14

Pathogenic lysosomal depletion in Parkinson's disease.
Benjamin Dehay, Jordi Bové, Natalia Rodríguez-Muela, Celine Perier, Ariadna Recasens, Patricia Boya, Miquel Vila. J Neurosci 2010
527
14

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice.
Emily M Rocha, Gaynor A Smith, Eric Park, Hongmei Cao, Anne-Renee Graham, Eilish Brown, Jesse R McLean, Melissa A Hayes, Jonathan Beagan, Sarah C Izen,[...]. Antioxid Redox Signal 2015
84
16

LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients.
Daniel Ysselstein, Maria Nguyen, Tiffany J Young, Alex Severino, Michael Schwake, Kalpana Merchant, Dimitri Krainc. Nat Commun 2019
84
16

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.
Emily M Rocha, Gaynor A Smith, Eric Park, Hongmei Cao, Eilish Brown, Melissa A Hayes, Jonathan Beagan, Jesse R McLean, Sarah C Izen, Eduardo Perez-Torres,[...]. Neurobiol Dis 2015
93
13

Alpha-Synuclein is degraded by both autophagy and the proteasome.
Julie L Webb, Brinda Ravikumar, Jane Atkins, Jeremy N Skepper, David C Rubinsztein. J Biol Chem 2003
13

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
13

A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson's disease.
Lena F Burbulla, Sohee Jeon, Jianbin Zheng, Pingping Song, Richard B Silverman, Dimitri Krainc. Sci Transl Med 2019
52
25

Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease.
Joana Magalhaes, Matthew E Gegg, Anna Migdalska-Richards, Mary K Doherty, Phillip D Whitfield, Anthony H V Schapira. Hum Mol Genet 2016
123
13

Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein.
Eun-Jin Bae, Na-Young Yang, Miyoung Song, Cheol Soon Lee, Jun Sung Lee, Byung Chul Jung, He-Jin Lee, Seokjoong Kim, Eliezer Masliah, Sergio Pablo Sardi,[...]. Nat Commun 2014
126
12

Differential effects of severe vs mild GBA mutations on Parkinson disease.
Ziv Gan-Or, Idan Amshalom, Laura L Kilarski, Anat Bar-Shira, Mali Gana-Weisz, Anat Mirelman, Karen Marder, Susan Bressman, Nir Giladi, Avi Orr-Urtreger. Neurology 2015
202
12

Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson’s disease.
Sarah K Abbott, Hongyun Li, Sonia Sanz Muñoz, Bianca Knoch, Marijka Batterham, Karen E Murphy, Glenda M Halliday, Brett Garner. Mov Disord 2014
80
15

Cerebrospinal fluid lysosomal enzymes and alpha-synuclein in Parkinson's disease.
Lucilla Parnetti, Davide Chiasserini, Emanuele Persichetti, Paolo Eusebi, Shiji Varghese, Mohammad M Qureshi, Andrea Dardis, Marta Deganuto, Claudia De Carlo, Anna Castrioto,[...]. Mov Disord 2014
163
12

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
Mickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, Anders Björklund. Proc Natl Acad Sci U S A 2013
480
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.