A citation-based method for searching scientific literature

Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa, Shane J Cronin, Roberto Nitsch, Carsten Schultz-Fademrecht, Jan Eickhoff, Sascha Menninger, Anke Unger, Robert Torka, Thomas Gruber, Reinhard Hinterleitner, Gottfried Baier, Dominik Wolf, Axel Ullrich, Bert M Klebl, Josef M Penninger. Nature 2014
Times Cited: 287







List of co-cited articles
1257 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
405
24

TAM receptors are pleiotropic inhibitors of the innate immune response.
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
702
22

TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
486
21


Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.
Heather M Seitz, Todd D Camenisch, Greg Lemke, H Shelton Earp, Glenn K Matsushima. J Immunol 2007
271
20

Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
140
17

Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.
Kathleen F Ludwig, Wenting Du, Noah B Sorrelle, Katarzyna Wnuk-Lipinska, Mary Topalovski, Jason E Toombs, Victoria H Cruz, Shinichi Yabuuchi, N V Rajeshkumar, Anirban Maitra,[...]. Cancer Res 2018
84
20

Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.
Canan Kasikara, Sushil Kumar, Stanley Kimani, Wen-I Tsou, Ke Geng, Viralkumar Davra, Ganapathy Sriram, Connor Devoe, Khanh-Quynh N Nguyen, Anita Antes,[...]. Mol Cancer Res 2017
74
21

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
J P O'Bryan, R A Frye, P C Cogswell, A Neubauer, B Kitch, C Prokop, R Espinosa, M M Le Beau, H S Earp, E T Liu. Mol Cell Biol 1991
623
16


Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases.
Anouk Caraux, Qingxian Lu, Nadine Fernandez, Sylvain Riou, James P Di Santo, David H Raulet, Greg Lemke, Claude Roth. Nat Immunol 2006
102
15

Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis.
Amanda Kirane, Kathleen F Ludwig, Noah Sorrelle, Gry Haaland, Tone Sandal, Renate Ranaweera, Jason E Toombs, Miao Wang, Sean P Dineen, David Micklem,[...]. Cancer Res 2015
94
15

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
Christine Gjerdrum, Crina Tiron, Torill Høiby, Ingunn Stefansson, Hallvard Haugen, Tone Sandal, Karin Collett, Shan Li, Emmet McCormack, Bjørn Tore Gjertsen,[...]. Proc Natl Acad Sci U S A 2010
406
15

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer.
Zhenfeng Zhang, Jae Cheol Lee, Luping Lin, Victor Olivas, Valerie Au, Thomas LaFramboise, Mohamed Abdel-Rahman, Xiaoqi Wang, Alan D Levine, Jin Kyung Rho,[...]. Nat Genet 2012
859
15

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis.
Rebecca S Cook, Kristen M Jacobsen, Anne M Wofford, Deborah DeRyckere, Jamie Stanford, Anne L Prieto, Elizabeth Redente, Melissa Sandahl, Debra M Hunter, Karen E Strunk,[...]. J Clin Invest 2013
111
14

Immunobiology of the TAM receptors.
Greg Lemke, Carla V Rothlin. Nat Rev Immunol 2008
563
14

Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
162
14

T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response.
Eugenio A Carrera Silva, Pamela Y Chan, Leonel Joannas, Andrea E Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida,[...]. Immunity 2013
117
13

TAM receptor signaling in immune homeostasis.
Carla V Rothlin, Eugenio A Carrera-Silva, Lidia Bosurgi, Sourav Ghosh. Annu Rev Immunol 2015
254
13

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
13

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
Erinn B Rankin, Katherine C Fuh, Laura Castellini, Kartik Viswanathan, Elizabeth C Finger, Anh N Diep, Edward L LaGory, Mihalis S Kariolis, Andy Chan, David Lindgren,[...]. Proc Natl Acad Sci U S A 2014
177
13

Diversification of TAM receptor tyrosine kinase function.
Anna Zagórska, Paqui G Través, Erin D Lew, Ian Dransfield, Greg Lemke. Nat Immunol 2014
252
12

MERTK as negative regulator of human T cell activation.
Raquel Cabezón, E Antonio Carrera-Silva, Georgina Flórez-Grau, Andrea E Errasti, Elisabeth Calderón-Gómez, Juan José Lozano, Carolina España, Elena Ricart, Julián Panés, Carla Vanina Rothlin,[...]. J Leukoc Biol 2015
60
20

Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor.
Yumi Yokoyama, Erin D Lew, Ruth Seelige, Elizabeth A Tindall, Colin Walsh, Patrick C Fagan, Jack Y Lee, Robin Nevarez, Joanne Oh, Kathleen D Tucker,[...]. Cancer Res 2019
42
28

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.
Marie-Anne Goyette, Stéphanie Duhamel, Léo Aubert, Ariane Pelletier, Paul Savage, Marie-Pier Thibault, Radia Marie Johnson, Peter Carmeliet, Mark Basik, Louis Gaboury,[...]. Cell Rep 2018
76
15

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
Lauren Averett Byers, Lixia Diao, Jing Wang, Pierre Saintigny, Luc Girard, Michael Peyton, Li Shen, Youhong Fan, Uma Giri, Praveen K Tumula,[...]. Clin Cancer Res 2013
663
12

Giving AXL the axe: targeting AXL in human malignancy.
Carl M Gay, Kavitha Balaji, Lauren Averett Byers. Br J Cancer 2017
166
12



Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer.
Canan Kasikara, Viralkumar Davra, David Calianese, Ke Geng, Thomas E Spires, Michael Quigley, Michael Wichroski, Ganapathy Sriram, Lucia Suarez-Lopez, Michael B Yaffe,[...]. Cancer Res 2019
50
24

Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer.
R M A Linger, R A Cohen, C T Cummings, S Sather, J Migdall-Wilson, D H G Middleton, X Lu, A E Barón, W A Franklin, D T Merrick,[...]. Oncogene 2013
140
12

Reprogramming the immunological microenvironment through radiation and targeting Axl.
Todd A Aguilera, Marjan Rafat, Laura Castellini, Hussein Shehade, Mihalis S Kariolis, Angela Bik-Yu Hui, Henning Stehr, Rie von Eyben, Dadi Jiang, Lesley G Ellies,[...]. Nat Commun 2016
100
12

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Sacha J Holland, Alison Pan, Christian Franci, Yuanming Hu, Betty Chang, Weiqun Li, Matt Duan, Allan Torneros, Jiaxin Yu, Thilo J Heckrodt,[...]. Cancer Res 2010
353
12

Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells.
Stefanie Loeser, Karin Loser, Martijn S Bijker, Manu Rangachari, Sjoerd H van der Burg, Teiji Wada, Stefan Beissert, Cornelis J M Melief, Josef M Penninger. J Exp Med 2007
103
11

MERTK Acts as a Costimulatory Receptor on Human CD8+ T Cells.
Marlies J W Peeters, Donata Dulkeviciute, Arianna Draghi, Cathrin Ritter, Anne Rahbech, Signe K Skadborg, Tina Seremet, Ana Micaela Carnaz Simões, Evelina Martinenaite, Hólmfridur R Halldórsdóttir,[...]. Cancer Immunol Res 2019
22
50

Tyro-3 family receptors are essential regulators of mammalian spermatogenesis.
Q Lu, M Gore, Q Zhang, T Camenisch, S Boast, F Casagranda, C Lai, M K Skinner, R Klein, G K Matsushima,[...]. Nature 1999
372
11


Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma.
Hirokazu Sadahiro, Kyung-Don Kang, Justin T Gibson, Mutsuko Minata, Hai Yu, Junfeng Shi, Rishi Chhipa, Zhihong Chen, Songjian Lu, Yannick Simoni,[...]. Cancer Res 2018
79
13

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.
Sonja Loges, Thomas Schmidt, Marc Tjwa, Katie van Geyte, Dirk Lievens, Esther Lutgens, Davy Vanhoutte, Delphine Borgel, Stephane Plaisance, Marc Hoylaerts,[...]. Blood 2010
120
11

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
587
11

Biology of the TAM receptors.
Greg Lemke. Cold Spring Harb Perspect Biol 2013
331
11

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.
K Bachmaier, C Krawczyk, I Kozieradzki, Y Y Kong, T Sasaki, A Oliveira-dos-Santos, S Mariathasan, D Bouchard, A Wakeham, A Itie,[...]. Nature 2000
528
10

Phagocytosis and clearance of apoptotic cells is mediated by MER.
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
862
10

AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells.
Hirokazu Taniguchi, Tadaaki Yamada, Rong Wang, Keiko Tanimura, Yuta Adachi, Akihiro Nishiyama, Azusa Tanimoto, Shinji Takeuchi, Luiz H Araujo, Mariana Boroni,[...]. Nat Commun 2019
134
10

An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies.
X Ye, Y Li, S Stawicki, S Couto, J Eastham-Anderson, D Kallop, R Weimer, Y Wu, L Pei. Oncogene 2010
159
10

MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity.
Alisa B Lee-Sherick, Kristen M Jacobsen, Curtis J Henry, Madeline G Huey, Rebecca E Parker, Lauren S Page, Amanda A Hill, Xiaodong Wang, Stephen V Frye, H Shelton Earp,[...]. JCI Insight 2018
38
23


The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.
Il-Kyoo Park, Chiara Giovenzana, Tiffany L Hughes, Jianhua Yu, Rossana Trotta, Michael A Caligiuri. Blood 2009
50
18

Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy.
W Leconet, C Larbouret, T Chardès, G Thomas, M Neiveyans, M Busson, M Jarlier, N Radosevic-Robin, M Pugnière, F Bernex,[...]. Oncogene 2014
70
12

Structural basis for Gas6-Axl signalling.
Takako Sasaki, Pjotr G Knyazev, Naomi J Clout, Yuri Cheburkin, Walter Göhring, Axel Ullrich, Rupert Timpl, Erhard Hohenester. EMBO J 2006
177
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.