A citation-based method for searching scientific literature

Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K Atianand, Matthijn R Vos, Gunnar F Schröder, Katherine A Fitzgerald, Hao Wu, Edward H Egelman. Cell 2014
Times Cited: 711







List of co-cited articles
1044 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
30


Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
28

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
28

Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
27

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Humayun Sharif, Li Wang, Wei Li Wang, Venkat Giri Magupalli, Liudmila Andreeva, Qi Qiao, Arthur V Hauenstein, Zhaolong Wu, Gabriel Núñez, Youdong Mao,[...]. Nature 2019
219
24

The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
23

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
23

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
23

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
22

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
22

Mechanisms and functions of inflammasomes.
Mohamed Lamkanfi, Vishva M Dixit. Cell 2014
21

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
530
21

Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
987
20

Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.
Xin Cai, Jueqi Chen, Hui Xu, Siqi Liu, Qiu-Xing Jiang, Randal Halfmann, Zhijian J Chen. Cell 2014
363
19

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Dave Boucher, Mercedes Monteleone, Rebecca C Coll, Kaiwen W Chen, Connie M Ross, Jessica L Teo, Guillermo A Gomez, Caroline L Holley, Damien Bierschenk, Katryn J Stacey,[...]. J Exp Med 2018
217
18

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Hexin Shi, Ying Wang, Xiaohong Li, Xiaoming Zhan, Miao Tang, Maggy Fina, Lijing Su, David Pratt, Chun Hui Bu, Sara Hildebrand,[...]. Nat Immunol 2016
353
17

ASC filament formation serves as a signal amplification mechanism for inflammasomes.
Mathias S Dick, Lorenzo Sborgi, Sebastian Rühl, Sebastian Hiller, Petr Broz. Nat Commun 2016
188
17

Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
16

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz Bauernfeind, Gabor Horvath, Daniel R Caffrey, Eicke Latz, Katherine A Fitzgerald. Nature 2009
15

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.
Hua Jiang, Hongbin He, Yun Chen, Wei Huang, Jinbo Cheng, Jin Ye, Aoli Wang, Jinhui Tao, Chao Wang, Qingsong Liu,[...]. J Exp Med 2017
280
15

Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
15

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
15

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Liman Zhang, Shuobing Chen, Jianbin Ruan, Jiayi Wu, Alexander B Tong, Qian Yin, Yang Li, Liron David, Alvin Lu, Wei Li Wang,[...]. Science 2015
225
15

Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation.
Christine Juliana, Teresa Fernandes-Alnemri, Seokwon Kang, Andrew Farias, Fengsong Qin, Emad S Alnemri. J Biol Chem 2012
451
14


The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Bernardo S Franklin, Lukas Bossaller, Dominic De Nardo, Jacqueline M Ratter, Andrea Stutz, Gudrun Engels, Christoph Brenker, Mark Nordhoff, Sandra R Mirandola, Ashraf Al-Amoudi,[...]. Nat Immunol 2014
462
14

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.
Teresa Fernandes-Alnemri, Je-Wook Yu, Pinaki Datta, Jianghong Wu, Emad S Alnemri. Nature 2009
14

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
912
14

Inflammatory caspases are innate immune receptors for intracellular LPS.
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
13

Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
13

NINJ1 mediates plasma membrane rupture during lytic cell death.
Nobuhiko Kayagaki, Opher S Kornfeld, Bettina L Lee, Irma B Stowe, Karen O'Rourke, Qingling Li, Wendy Sandoval, Donghong Yan, Jing Kang, Min Xu,[...]. Nature 2021
103
13

Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
Bénédicte F Py, Mi-Sung Kim, Helin Vakifahmetoglu-Norberg, Junying Yuan. Mol Cell 2013
403
12

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
893
12

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
12

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
232
12

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation.
T Fernandes-Alnemri, J Wu, J-W Yu, P Datta, B Miller, W Jankowski, S Rosenberg, J Zhang, E S Alnemri. Cell Death Differ 2007
646
12

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Veit Hornung, Franz Bauernfeind, Annett Halle, Eivind O Samstad, Hajime Kono, Kenneth L Rock, Katherine A Fitzgerald, Eicke Latz. Nat Immunol 2008
11

Inflammasomes in health and disease.
Till Strowig, Jorge Henao-Mejia, Eran Elinav, Richard Flavell. Nature 2012
11

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
281
11

Inflammasomes and their roles in health and disease.
Mohamed Lamkanfi, Vishva M Dixit. Annu Rev Cell Dev Biol 2012
613
11

Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
11

Structural and biochemical basis for induced self-propagation of NLRC4.
Zehan Hu, Qiang Zhou, Chenlu Zhang, Shilong Fan, Wei Cheng, Yue Zhao, Feng Shao, Hong-Wei Wang, Sen-Fang Sui, Jijie Chai. Science 2015
213
11

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
458
11

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
Geun-Shik Lee, Naeha Subramanian, Andrew I Kim, Ivona Aksentijevich, Raphaela Goldbach-Mansky, David B Sacks, Ronald N Germain, Daniel L Kastner, Jae Jin Chae. Nature 2012
574
10

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.
V Pétrilli, S Papin, C Dostert, A Mayor, F Martinon, J Tschopp. Cell Death Differ 2007
984
10

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
517
10

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling.
Joseph A Duncan, Daniel T Bergstralh, Yanhong Wang, Stephen B Willingham, Zhengmao Ye, Albert G Zimmermann, Jenny Pan-Yun Ting. Proc Natl Acad Sci U S A 2007
303
10

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation.
Jonathan L Schmid-Burgk, Dhruv Chauhan, Tobias Schmidt, Thomas S Ebert, Julia Reinhardt, Elmar Endl, Veit Hornung. J Biol Chem 2016
245
10

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,[...]. EMBO Mol Med 2018
180
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.