A citation-based method for searching scientific literature

Tomohiro Koga, Christian M Hedrich, Masayuki Mizui, Nobuya Yoshida, Kotaro Otomo, Linda A Lieberman, Thomas Rauen, José C Crispín, George C Tsokos. J Clin Invest 2014
Times Cited: 110







List of co-cited articles
1053 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Systemic lupus erythematosus.
George C Tsokos. N Engl J Med 2011
33

Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus.
Tomohiro Koga, Kunihiro Ichinose, Masayuki Mizui, José C Crispín, George C Tsokos. J Immunol 2012
62
43

Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV.
Yuang-Taung Juang, Ying Wang, Elena E Solomou, Yansong Li, Christian Mawrin, Klaus Tenbrock, Vasileios C Kyttaris, George C Tsokos. J Clin Invest 2005
154
25

KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3⁺ regulatory T cells in MRL/lpr mice.
Tomohiro Koga, Masayuki Mizui, Nobuya Yoshida, Kotaro Otomo, Linda A Lieberman, José C Crispín, George C Tsokos. Autoimmunity 2014
47
51

Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV.
Kunihiro Ichinose, Yuang-Taung Juang, José C Crispín, Katalin Kis-Toth, George C Tsokos. Arthritis Rheum 2011
61
39

Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys.
José C Crispín, Mohamed Oukka, George Bayliss, Robert A Cohen, Christine A Van Beek, Isaac E Stillman, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Immunol 2008
482
24

Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
291
24

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
198
23



The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Greg M Delgoffe, Kristen N Pollizzi, Adam T Waickman, Emily Heikamp, David J Meyers, Maureen R Horton, Bo Xiao, Paul F Worley, Jonathan D Powell. Nat Immunol 2011
707
18

cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus.
Christian M Hedrich, Jose C Crispin, Thomas Rauen, Christina Ioannidis, Sokratis A Apostolidis, Mindy S Lo, Vasileios C Kyttaris, George C Tsokos. Proc Natl Acad Sci U S A 2012
59
30

Phosphatase PP2A is requisite for the function of regulatory T cells.
Sokratis A Apostolidis, Noé Rodríguez-Rodríguez, Abel Suárez-Fueyo, Nikolina Dioufa, Esra Ozcan, José C Crispín, Maria G Tsokos, George C Tsokos. Nat Immunol 2016
116
18

Cutting edge: Calcium/Calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis.
Kunihiro Ichinose, Thomas Rauen, Yuang-Taung Juang, Katalin Kis-Toth, Masayuki Mizui, Tomohiro Koga, George C Tsokos. J Immunol 2011
43
39

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.
Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone,[...]. J Immunol 2013
75
22

Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.
David Fernandez, Eduardo Bonilla, Naureen Mirza, Brian Niland, Andras Perl. Arthritis Rheum 2006
200
17


Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
149
16

IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells.
Masayuki Mizui, Tomohiro Koga, Linda A Lieberman, Jessica Beltran, Nobuya Yoshida, Mark C Johnson, Roland Tisch, George C Tsokos. J Immunol 2014
65
23

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
982
15


cAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3+CD4-CD8- T cells in health and disease.
Christian M Hedrich, Thomas Rauen, Jose C Crispin, Tomohiro Koga, Christina Ioannidis, Melissa Zajdel, Vasileios C Kyttaris, George C Tsokos. J Biol Chem 2013
34
41

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
14

IL-17 and Th17 Cells.
Thomas Korn, Estelle Bettelli, Mohamed Oukka, Vijay K Kuchroo. Annu Rev Immunol 2009
13

CREMα overexpression decreases IL-2 production, induces a T(H)17 phenotype and accelerates autoimmunity.
Ralph Lippe, Kim Ohl, Georg Varga, Thomas Rauen, Jose C Crispin, Yuang-Taung Juang, Stefanie Kuerten, Frank Tacke, Marc Wolf, Kirsten Roebrock,[...]. J Mol Cell Biol 2012
27
48

Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin.
Andras Perl, Robert Hanczko, Zhi-Wei Lai, Zachary Oaks, Ryan Kelly, Rebecca Borsuk, John M Asara, Paul E Phillips. Metabolomics 2015
66
19


Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus.
Caroline von Spee-Mayer, Elise Siegert, Dimas Abdirama, Angelika Rose, Anika Klaus, Tobias Alexander, Philipp Enghard, Birgit Sawitzki, Falk Hiepe, Andreas Radbruch,[...]. Ann Rheum Dis 2016
173
13

Lupus Nephritis IgG Induction of Calcium/Calmodulin-Dependent Protein Kinase IV Expression in Podocytes and Alteration of Their Function.
Kunihiro Ichinose, Takeshi Ushigusa, Ayako Nishino, Yosikazu Nakashima, Takahisa Suzuki, Yoshiro Horai, Tomohiro Koga, Shin-ya Kawashiri, Naoki Iwamoto, Mami Tamai,[...]. Arthritis Rheumatol 2016
33
39

Cutting Edge: Nanogel-Based Delivery of an Inhibitor of CaMK4 to CD4+ T Cells Suppresses Experimental Autoimmune Encephalomyelitis and Lupus-like Disease in Mice.
Kotaro Otomo, Tomohiro Koga, Masayuki Mizui, Nobuya Yoshida, Christina Kriegel, Sean Bickerton, Tarek M Fahmy, George C Tsokos. J Immunol 2015
30
43

ICER is requisite for Th17 differentiation.
Nobuya Yoshida, Denis Comte, Masayuki Mizui, Kotaro Otomo, Florencia Rosetti, Tanya N Mayadas, José C Crispín, Sean J Bradley, Tomohiro Koga, Michihito Kono,[...]. Nat Commun 2016
32
40

cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells.
Christian M Hedrich, José C Crispín, Thomas Rauen, Christina Ioannidis, Tomohiro Koga, Noe Rodriguez Rodriguez, Sokratis A Apostolidis, Vasileios C Kyttaris, George C Tsokos. J Biol Chem 2014
43
27

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
David R Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A Middleton, Paul E Phillips, Mary K Crow, Stefanie Oess, Werner Muller-Esterl,[...]. J Immunol 2009
148
12

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Greg M Delgoffe, Thomas P Kole, Yan Zheng, Paul E Zarek, Krystal L Matthews, Bo Xiao, Paul F Worley, Sara C Kozma, Jonathan D Powell. Immunity 2009
784
12

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
458
12

Calcium/Calmodulin-Dependent Kinase IV Facilitates the Recruitment of Interleukin-17-Producing Cells to Target Organs Through the CCR6/CCL20 Axis in Th17 Cell-Driven Inflammatory Diseases.
Tomohiro Koga, Kotaro Otomo, Masayuki Mizui, Nobuya Yoshida, Masataka Umeda, Kunihiro Ichinose, Atsushi Kawakami, George C Tsokos. Arthritis Rheumatol 2016
29
41

Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus.
E E Solomou, Y T Juang, M F Gourley, G M Kammer, G C Tsokos. J Immunol 2001
141
11

Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE.
Jens Y Humrich, Caroline von Spee-Mayer, Elise Siegert, Tobias Alexander, Falk Hiepe, Andreas Radbruch, Gerd-Rüdiger Burmester, Gabriela Riemekasten. Ann Rheum Dis 2015
105
11

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.
Tiffany N Caza, David R Fernandez, Gergely Talaber, Zachary Oaks, Mark Haas, Michael P Madaio, Zhi-Wei Lai, Gabriella Miklossy, Ram R Singh, Dmitriy M Chudakov,[...]. Ann Rheum Dis 2014
76
14

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
John P Ray, Matthew M Staron, Justin A Shyer, Ping-Chih Ho, Heather D Marshall, Simon M Gray, Brian J Laidlaw, Koichi Araki, Rafi Ahmed, Susan M Kaech,[...]. Immunity 2015
168
11

Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
Jing He, Xia Zhang, Yunbo Wei, Xiaolin Sun, Yaping Chen, Jun Deng, Yuebo Jin, Yuzhou Gan, Xin Hu, Rulin Jia,[...]. Nat Med 2016
257
11

Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.
Mako Nakaya, Yichuan Xiao, Xiaofei Zhou, Jae-Hoon Chang, Mikyoung Chang, Xuhong Cheng, Marzenna Blonska, Xin Lin, Shao-Cong Sun. Immunity 2014
370
11

Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells.
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, George C Tsokos. Proc Natl Acad Sci U S A 2018
36
30

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.
Arian Laurence, Cristina M Tato, Todd S Davidson, Yuka Kanno, Zhi Chen, Zhengju Yao, Rebecca B Blank, Françoise Meylan, Richard Siegel, Lothar Hennighausen,[...]. Immunity 2007
10

cAMP responsive element modulator: a critical regulator of cytokine production.
Thomas Rauen, Christian M Hedrich, Klaus Tenbrock, George C Tsokos. Trends Mol Med 2013
41
24

Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodeling.
Sokratis A Apostolidis, Thomas Rauen, Christian M Hedrich, George C Tsokos, José C Crispín. J Biol Chem 2013
46
21

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.
Andrew N Macintyre, Valerie A Gerriets, Amanda G Nichols, Ryan D Michalek, Michael C Rudolph, Divino Deoliveira, Steven M Anderson, E Dale Abel, Benny J Chen, Laura P Hale,[...]. Cell Metab 2014
510
10

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
Ruoning Wang, Christopher P Dillon, Lewis Zhichang Shi, Sandra Milasta, Robert Carter, David Finkelstein, Laura L McCormick, Patrick Fitzgerald, Hongbo Chi, Joshua Munger,[...]. Immunity 2011
10

Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice.
Zachary Oaks, Thomas Winans, Tiffany Caza, David Fernandez, Yuxin Liu, Steve K Landas, Katalin Banki, Andras Perl. Arthritis Rheumatol 2016
52
19

Immunometabolism in systemic lupus erythematosus.
Laurence Morel. Nat Rev Rheumatol 2017
97
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.