A citation-based method for searching scientific literature

J R Riordan, J M Rommens, B Kerem, N Alon, R Rozmahel, Z Grzelczak, J Zielenski, S Lok, N Plavsic, J L Chou. Science 1989
Times Cited: 5719







List of co-cited articles
752 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Identification of the cystic fibrosis gene: genetic analysis.
B Kerem, J M Rommens, J A Buchanan, D Markiewicz, T K Cox, A Chakravarti, M Buchwald, L C Tsui. Science 1989
27

A CFTR potentiator in patients with cystic fibrosis and the G551D mutation.
Bonnie W Ramsey, Jane Davies, N Gerard McElvaney, Elizabeth Tullis, Scott C Bell, Pavel Dřevínek, Matthias Griese, Edward F McKone, Claire E Wainwright, Michael W Konstan,[...]. N Engl J Med 2011
24

Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.
Claire E Wainwright, J Stuart Elborn, Bonnie W Ramsey, Gautham Marigowda, Xiaohong Huang, Marco Cipolli, Carla Colombo, Jane C Davies, Kris De Boeck, Patrick A Flume,[...]. N Engl J Med 2015
764
23

Identification of the cystic fibrosis gene: chromosome walking and jumping.
J M Rommens, M C Iannuzzi, B Kerem, M L Drumm, G Melmer, M Dean, R Rozmahel, J L Cole, D Kennedy, N Hidaka. Science 1989
22

VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.
Dominic Keating, Gautham Marigowda, Lucy Burr, Cori Daines, Marcus A Mall, Edward F McKone, Bonnie W Ramsey, Steven M Rowe, Laura A Sass, Elizabeth Tullis,[...]. N Engl J Med 2018
222
20

Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
Peter G Middleton, Marcus A Mall, Pavel Dřevínek, Larry C Lands, Edward F McKone, Deepika Polineni, Bonnie W Ramsey, Jennifer L Taylor-Cousar, Elizabeth Tullis, François Vermeulen,[...]. N Engl J Med 2019
331
20

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.
Fredrick Van Goor, Sabine Hadida, Peter D J Grootenhuis, Bill Burton, Jeffrey H Stack, Kimberly S Straley, Caroline J Decker, Mark Miller, Jason McCartney, Eric R Olson,[...]. Proc Natl Acad Sci U S A 2011
680
18

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770.
Fredrick Van Goor, Sabine Hadida, Peter D J Grootenhuis, Bill Burton, Dong Cao, Tim Neuberger, Amanda Turnbull, Ashvani Singh, John Joubran, Anna Hazlewood,[...]. Proc Natl Acad Sci U S A 2009
733
18

Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.
Harry G M Heijerman, Edward F McKone, Damian G Downey, Eva Van Braeckel, Steven M Rowe, Elizabeth Tullis, Marcus A Mall, John J Welter, Bonnie W Ramsey, Charlotte M McKee,[...]. Lancet 2019
224
17

Cystic fibrosis.
Steven M Rowe, Stacey Miller, Eric J Sorscher. N Engl J Med 2005
17

Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del.
Jennifer L Taylor-Cousar, Anne Munck, Edward F McKone, Cornelis K van der Ent, Alexander Moeller, Christopher Simard, Linda T Wang, Edward P Ingenito, Charlotte McKee, Yimeng Lu,[...]. N Engl J Med 2017
304
16

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.
Gudio Veit, Radu G Avramescu, Annette N Chiang, Scott A Houck, Zhiwei Cai, Kathryn W Peters, Jeong S Hong, Harvey B Pollard, William B Guggino, William E Balch,[...]. Mol Biol Cell 2016
218
16

Cystic fibrosis.
J Stuart Elborn. Lancet 2016
630
15

Cystic fibrosis.
Brian P O'Sullivan, Steven D Freedman. Lancet 2009
780
12

Tezacaftor-Ivacaftor in Residual-Function Heterozygotes with Cystic Fibrosis.
Steven M Rowe, Cori Daines, Felix C Ringshausen, Eitan Kerem, John Wilson, Elizabeth Tullis, Nitin Nair, Christopher Simard, Linda Han, Edward P Ingenito,[...]. N Engl J Med 2017
202
11

Molecular Structure of the Human CFTR Ion Channel.
Fangyu Liu, Zhe Zhang, László Csanády, David C Gadsby, Jue Chen. Cell 2017
220
11

Cystic fibrosis.
Felix Ratjen, Scott C Bell, Steven M Rowe, Christopher H Goss, Alexandra L Quittner, Andrew Bush. Nat Rev Dis Primers 2015
195
10

The future of cystic fibrosis care: a global perspective.
Scott C Bell, Marcus A Mall, Hector Gutierrez, Milan Macek, Susan Madge, Jane C Davies, Pierre-Régis Burgel, Elizabeth Tullis, Claudio Castaños, Carlo Castellani,[...]. Lancet Respir Med 2020
158
10

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis.
S H Cheng, R J Gregory, J Marshall, S Paul, D W Souza, G A White, C R O'Riordan, A E Smith. Cell 1990
10

Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene.
Patrick R Sosnay, Karen R Siklosi, Fredrick Van Goor, Kyle Kaniecki, Haihui Yu, Neeraj Sharma, Anabela S Ramalho, Margarida D Amaral, Ruslan Dorfman, Julian Zielenski,[...]. Nat Genet 2013
347
9

A functional CFTR assay using primary cystic fibrosis intestinal organoids.
Johanna F Dekkers, Caroline L Wiegerinck, Hugo R de Jonge, Inez Bronsveld, Hettie M Janssens, Karin M de Winter-de Groot, Arianne M Brandsma, Nienke W M de Jong, Marcel J C Bijvelds, Bob J Scholte,[...]. Nat Med 2013
495
9

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.
Daniel T Montoro, Adam L Haber, Moshe Biton, Vladimir Vinarsky, Brian Lin, Susan E Birket, Feng Yuan, Sijia Chen, Hui Min Leung, Jorge Villoria,[...]. Nature 2018
340
9

Correction of CFTR function in nasal epithelial cells from cystic fibrosis patients predicts improvement of respiratory function by CFTR modulators.
Iwona M Pranke, Aurélie Hatton, Juliette Simonin, Jean Philippe Jais, Françoise Le Pimpec-Barthes, Ania Carsin, Pierre Bonnette, Michael Fayon, Nathalie Stremler-Le Bel, Dominique Grenet,[...]. Sci Rep 2017
67
13

VX-659-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.
Jane C Davies, Samuel M Moskowitz, Cynthia Brown, Alexander Horsley, Marcus A Mall, Edward F McKone, Barry J Plant, Dario Prais, Bonnie W Ramsey, Jennifer L Taylor-Cousar,[...]. N Engl J Med 2018
149
8

Progress in therapies for cystic fibrosis.
Kris De Boeck, Margarida D Amaral. Lancet Respir Med 2016
150
8

Structure-guided combination therapy to potently improve the function of mutant CFTRs.
Guido Veit, Haijin Xu, Elise Dreano, Radu G Avramescu, Miklos Bagdany, Lenore K Beitel, Ariel Roldan, Mark A Hancock, Cecilia Lay, Wei Li,[...]. Nat Med 2018
49
16



Molecular structure of the ATP-bound, phosphorylated human CFTR.
Zhe Zhang, Fangyu Liu, Jue Chen. Proc Natl Acad Sci U S A 2018
69
11

Requirements for efficient correction of ΔF508 CFTR revealed by analyses of evolved sequences.
Juan L Mendoza, André Schmidt, Qin Li, Emmanuel Nuvaga, Tyler Barrett, Robert J Bridges, Andrew P Feranchak, Chad A Brautigam, Philip J Thomas. Cell 2012
180
7


Peripheral protein quality control removes unfolded CFTR from the plasma membrane.
Tsukasa Okiyoneda, Hervé Barrière, Miklós Bagdány, Wael M Rabeh, Kai Du, Jörg Höhfeld, Jason C Young, Gergely L Lukacs. Science 2010
293
7

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte.
Lindsey W Plasschaert, Rapolas Žilionis, Rayman Choo-Wing, Virginia Savova, Judith Knehr, Guglielmo Roma, Allon M Klein, Aron B Jaffe. Nature 2018
321
7

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity.
Anke Di, Mary E Brown, Ludmila V Deriy, Chunying Li, Frances L Szeto, Yimei Chen, Ping Huang, Jiankun Tong, Anjaparavanda P Naren, Vytautas Bindokas,[...]. Nat Cell Biol 2006
324
7

Demonstration that CFTR is a chloride channel by alteration of its anion selectivity.
M P Anderson, R J Gregory, S Thompson, D W Souza, S Paul, R C Mulligan, A E Smith, M J Welsh. Science 1991
923
7

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination.
Guido Veit, Ariel Roldan, Mark A Hancock, Dillon F Da Fonte, Haijin Xu, Maytham Hussein, Saul Frenkiel, Elias Matouk, Tony Velkov, Gergely L Lukacs. JCI Insight 2020
22
31

Risk factors for bronchiectasis in children with cystic fibrosis.
Peter D Sly, Catherine L Gangell, Linping Chen, Robert S Ware, Sarath Ranganathan, Lauren S Mott, Conor P Murray, Stephen M Stick. N Engl J Med 2013
338
6

Efficacy and safety of ivacaftor in patients aged 6 to 11 years with cystic fibrosis with a G551D mutation.
Jane C Davies, Claire E Wainwright, Gerard J Canny, Mark A Chilvers, Michelle S Howenstine, Anne Munck, Jochen G Mainz, Sally Rodriguez, Haihong Li, Karl Yen,[...]. Am J Respir Crit Care Med 2013
291
6

Disease progression in patients with cystic fibrosis treated with ivacaftor: Data from national US and UK registries.
Nataliya Volkova, Kristin Moy, Jennifer Evans, Daniel Campbell, Simon Tian, Christopher Simard, Mark Higgins, Michael W Konstan, Gregory S Sawicki, Alexander Elbert,[...]. J Cyst Fibros 2020
53
11

Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function.
Wael M Rabeh, Florian Bossard, Haijin Xu, Tsukasa Okiyoneda, Miklos Bagdany, Cory M Mulvihill, Kai Du, Salvatore di Bernardo, Yuhong Liu, Lars Konermann,[...]. Cell 2012
194
6

Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction.
Carlos M Farinha, John King-Underwood, Marisa Sousa, Ana Raquel Correia, Bárbara J Henriques, Mónica Roxo-Rosa, Ana Carina Da Paula, Jonathan Williams, Simon Hirst, Cláudio M Gomes,[...]. Chem Biol 2013
99
6

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis.
Volker Teichgräber, Martina Ulrich, Nicole Endlich, Joachim Riethmüller, Barbara Wilker, Cheyla Conceição De Oliveira-Munding, Anna M van Heeckeren, Mark L Barr, Gabriele von Kürthy, Kurt W Schmid,[...]. Nat Med 2008
401
6

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung.
Alejandro A Pezzulo, Xiao Xiao Tang, Mark J Hoegger, Mahmoud H Abou Alaiwa, Shyam Ramachandran, Thomas O Moninger, Phillip H Karp, Christine L Wohlford-Lenane, Henk P Haagsman, Martin van Eijk,[...]. Nature 2012
466
6



Ivacaftor treatment of cystic fibrosis in children aged 12 to <24 months and with a CFTR gating mutation (ARRIVAL): a phase 3 single-arm study.
Margaret Rosenfeld, Claire E Wainwright, Mark Higgins, Linda T Wang, Charlotte McKee, Daniel Campbell, Simon Tian, Jennifer Schneider, Steve Cunningham, Jane C Davies. Lancet Respir Med 2018
84
5

Ivacaftor potentiation of multiple CFTR channels with gating mutations.
Haihui Yu, Bill Burton, Chien-Jung Huang, Jennings Worley, Dong Cao, James P Johnson, Art Urrutia, John Joubran, Sheila Seepersaud, Katherine Sussky,[...]. J Cyst Fibros 2012
254
5

Assessment of safety and efficacy of long-term treatment with combination lumacaftor and ivacaftor therapy in patients with cystic fibrosis homozygous for the F508del-CFTR mutation (PROGRESS): a phase 3, extension study.
Michael W Konstan, Edward F McKone, Richard B Moss, Gautham Marigowda, Simon Tian, David Waltz, Xiaohong Huang, Barry Lubarsky, Jaime Rubin, Stefanie J Millar,[...]. Lancet Respir Med 2017
138
5

Orkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue.
Steven V Molinski, Saumel Ahmadi, Wan Ip, Hong Ouyang, Adriana Villella, John P Miller, Po-Shun Lee, Kethika Kulleperuma, Kai Du, Michelle Di Paola,[...]. EMBO Mol Med 2017
57
8

Data from the US and UK cystic fibrosis registries support disease modification by CFTR modulation with ivacaftor.
Leona Bessonova, Nataliya Volkova, Mark Higgins, Leif Bengtsson, Simon Tian, Christopher Simard, Michael W Konstan, Gregory S Sawicki, Ase Sewall, Stephen Nyangoma,[...]. Thorax 2018
57
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.