A citation-based method for searching scientific literature

Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
Times Cited: 326







List of co-cited articles
1351 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
528
20

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
17

Notch Signaling in Development, Tissue Homeostasis, and Disease.
Chris Siebel, Urban Lendahl. Physiol Rev 2017
413
17

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
16

Notch signalling in context.
Sarah J Bray. Nat Rev Mol Cell Biol 2016
516
15

The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
326
15

Notch signaling: simplicity in design, versatility in function.
Emma R Andersson, Rickard Sandberg, Urban Lendahl. Development 2011
645
15

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update.
Naoko Takebe, Lucio Miele, Pamela Jo Harris, Woondong Jeong, Hideaki Bando, Michael Kahn, Sherry X Yang, S Percy Ivy. Nat Rev Clin Oncol 2015
767
12

Notch signaling: an emerging therapeutic target for cancer treatment.
Xun Yuan, Hua Wu, Hanxiao Xu, Huihua Xiong, Qian Chu, Shiying Yu, Gen Sheng Wu, Kongming Wu. Cancer Lett 2015
251
11

γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
Yong Ran, Fokhrul Hossain, Antonio Pannuti, Christian B Lessard, Gabriela Z Ladd, Joo In Jung, Lisa M Minter, Barbara A Osborne, Lucio Miele, Todd E Golde. EMBO Mol Med 2017
87
12

Notch signalling in solid tumours: a little bit of everything but not all the time.
Prathibha Ranganathan, Kelly L Weaver, Anthony J Capobianco. Nat Rev Cancer 2011
584
11

Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
568
11

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
11

Notch signaling at a glance.
Kazuya Hori, Anindya Sen, Spyros Artavanis-Tsakonas. J Cell Sci 2013
369
10

The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.
Rhett A Kovall, Brian Gebelein, David Sprinzak, Raphael Kopan. Dev Cell 2017
182
10

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
85
10


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
8

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
73
10

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko,[...]. PLoS One 2010
133
8

A phase I dose-escalation and dose-expansion study of brontictuzumab in subjects with selected solid tumors.
R Ferrarotto, G Eckhardt, A Patnaik, P LoRusso, L Faoro, J V Heymach, A M Kapoun, L Xu, P Munster. Ann Oncol 2018
48
16

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
53
15

Notch promotes radioresistance of glioma stem cells.
Jialiang Wang, Timothy P Wakeman, Justin D Lathia, Anita B Hjelmeland, Xiao-Fan Wang, Rebekah R White, Jeremy N Rich, Bruce A Sullenger. Stem Cells 2010
431
8

A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors.
David C Smith, Rashmi Chugh, Amita Patnaik, Kyriakos P Papadopoulos, Min Wang, Ann M Kapoun, Lu Xu, Jakob Dupont, Robert J Stagg, Anthony Tolcher. Invest New Drugs 2019
32
25


The Notch signaling pathway as a mediator of tumor survival.
Kathleen M Capaccione, Sharon R Pine. Carcinogenesis 2013
185
7

Notch signalling: a simple pathway becomes complex.
Sarah J Bray. Nat Rev Mol Cell Biol 2006
7

Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors.
Ian Krop, Tim Demuth, Tina Guthrie, Patrick Y Wen, Warren P Mason, Prakash Chinnaiyan, Nicholas Butowski, Morris D Groves, Santosh Kesari, Steven J Freedman,[...]. J Clin Oncol 2012
217
7

From fly wings to targeted cancer therapies: a centennial for notch signaling.
Panagiotis Ntziachristos, Jing Shan Lim, Julien Sage, Iannis Aifantis. Cancer Cell 2014
242
7

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia.
A Joutel, C Corpechot, A Ducros, K Vahedi, H Chabriat, P Mouton, S Alamowitch, V Domenga, M Cécillion, E Marechal,[...]. Nature 1996
7

Notch Signaling in the Tumor Microenvironment.
Olivier Meurette, Patrick Mehlen. Cancer Cell 2018
237
7

γ-Secretase inhibitors and modulators.
Todd E Golde, Edward H Koo, Kevin M Felsenstein, Barbara A Osborne, Lucio Miele. Biochim Biophys Acta 2013
196
7

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.
Dan R Robinson, Shanker Kalyana-Sundaram, Yi-Mi Wu, Sunita Shankar, Xuhong Cao, Bushra Ateeq, Irfan A Asangani, Matthew Iyer, Christopher A Maher, Catherine S Grasso,[...]. Nat Med 2011
247
7

Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.
Hannah Harrison, Gillian Farnie, Sacha J Howell, Rebecca E Rock, Spyros Stylianou, Keith R Brennan, Nigel J Bundred, Robert B Clarke. Cancer Res 2010
378
7

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.
Anne F Schott, Melissa D Landis, Gabriela Dontu, Kent A Griffith, Rachel M Layman, Ian Krop, Lacey A Paskett, Helen Wong, Lacey E Dobrolecki, Michael T Lewis,[...]. Clin Cancer Res 2013
165
7

Notch as a tumour suppressor.
Craig S Nowell, Freddy Radtke. Nat Rev Cancer 2017
202
7

Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties.
Leopoldo Luistro, Wei He, Melissa Smith, Kathryn Packman, Maria Vilenchik, Daisy Carvajal, John Roberts, James Cai, Windy Berkofsky-Fessler, Holly Hilton,[...]. Cancer Res 2009
146
6

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival.
Michael Reedijk, Silvia Odorcic, Lynn Chang, Hui Zhang, Naomi Miller, David R McCready, Gina Lockwood, Sean E Egan. Cancer Res 2005
574
6

Prospective identification of tumorigenic breast cancer cells.
Muhammad Al-Hajj, Max S Wicha, Adalberto Benito-Hernandez, Sean J Morrison, Michael F Clarke. Proc Natl Acad Sci U S A 2003
6

Notch1 functions as a tumor suppressor in mouse skin.
Michael Nicolas, Anita Wolfer, Kenneth Raj, J Alain Kummer, Pleasantine Mill, Mascha van Noort, Chi-chung Hui, Hans Clevers, G Paolo Dotto, Freddy Radtke. Nat Genet 2003
767
6

NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth.
Thaned Kangsamaksin, Aino Murtomaki, Natalie M Kofler, Henar Cuervo, Reyhaan A Chaudhri, Ian W Tattersall, Paul E Rosenstiel, Carrie J Shawber, Jan Kitajewski. Cancer Discov 2015
104
6

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
6

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells.
Emanuela Rosati, Rita Sabatini, Giuliana Rampino, Antonio Tabilio, Mauro Di Ianni, Katia Fettucciari, Andrea Bartoli, Stefano Coaccioli, Isabella Screpanti, Pierfrancesco Marconi. Blood 2009
225
6

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.
Giulia Fabbri, Silvia Rasi, Davide Rossi, Vladimir Trifonov, Hossein Khiabanian, Jing Ma, Adina Grunn, Marco Fangazio, Daniela Capello, Sara Monti,[...]. J Exp Med 2011
447
6

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Nicholas J Wang, Zachary Sanborn, Kelly L Arnett, Laura J Bayston, Wilson Liao, Charlotte M Proby, Irene M Leigh, Eric A Collisson, Patricia B Gordon, Lakshmi Jakkula,[...]. Proc Natl Acad Sci U S A 2011
321
6

Notch inhibitors for cancer treatment.
Ingrid Espinoza, Lucio Miele. Pharmacol Ther 2013
208
6

Rational targeting of Notch signaling in cancer.
P Rizzo, C Osipo, K Foreman, T Golde, B Osborne, L Miele. Oncogene 2008
305
6

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
507
6

A phase I dose escalation and expansion study of the anticancer stem cell agent demcizumab (anti-DLL4) in patients with previously treated solid tumors.
David C Smith, Peter D Eisenberg, Georgy Manikhas, Rashmi Chugh, Matthew A Gubens, Robert J Stagg, Ann M Kapoun, Lu Xu, Jakob Dupont, Branimir Sikic. Clin Cancer Res 2014
97
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.