Nadia Canu, Maria Teresa Ciotti, Loredano Pollegioni. Front Synaptic Neurosci 2014
Times Cited: 21
Times Cited: 21
Times Cited
Times Co-cited
Similarity
The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding.
Myron A Smith, Volker Mack, Andreas Ebneth, Isabel Moraes, Brunella Felicetti, Michael Wood, Dorian Schonfeld, Owen Mather, Andrea Cesura, John Barker. J Biol Chem 2010
Myron A Smith, Volker Mack, Andreas Ebneth, Isabel Moraes, Brunella Felicetti, Michael Wood, Dorian Schonfeld, Owen Mather, Andrea Cesura, John Barker. J Biol Chem 2010
47
Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission.
H Wolosker, S Blackshaw, S H Snyder. Proc Natl Acad Sci U S A 1999
H Wolosker, S Blackshaw, S H Snyder. Proc Natl Acad Sci U S A 1999
47
Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity.
Veronika N Foltyn, Inna Bendikov, Joari De Miranda, Rogerio Panizzutti, Elena Dumin, Maria Shleper, Pu Li, Michael D Toney, Elena Kartvelishvily, Herman Wolosker. J Biol Chem 2005
Veronika N Foltyn, Inna Bendikov, Joari De Miranda, Rogerio Panizzutti, Elena Dumin, Maria Shleper, Pu Li, Michael D Toney, Elena Kartvelishvily, Herman Wolosker. J Biol Chem 2005
42
Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe.
Masaru Goto, Takae Yamauchi, Nobuo Kamiya, Ikuko Miyahara, Tohru Yoshimura, Hisaaki Mihara, Tatsuo Kurihara, Ken Hirotsu, Nobuyoshi Esaki. J Biol Chem 2009
Masaru Goto, Takae Yamauchi, Nobuo Kamiya, Ikuko Miyahara, Tohru Yoshimura, Hisaaki Mihara, Tatsuo Kurihara, Ken Hirotsu, Nobuyoshi Esaki. J Biol Chem 2009
38
Phosphorylation of mouse serine racemase regulates D-serine synthesis.
Veronika N Foltyn, Martin Zehl, Elena Dikopoltsev, Ole N Jensen, Herman Wolosker. FEBS Lett 2010
Veronika N Foltyn, Martin Zehl, Elena Dikopoltsev, Ole N Jensen, Herman Wolosker. FEBS Lett 2010
38
ATP binding to human serine racemase is cooperative and modulated by glycine.
Marialaura Marchetti, Stefano Bruno, Barbara Campanini, Alessio Peracchi, Nicole Mai, Andrea Mozzarelli. FEBS J 2013
Marialaura Marchetti, Stefano Bruno, Barbara Campanini, Alessio Peracchi, Nicole Mai, Andrea Mozzarelli. FEBS J 2013
38
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation.
Asif K Mustafa, Manish Kumar, Balakrishnan Selvakumar, Gary P H Ho, Jeffrey T Ehmsen, Roxanne K Barrow, L Mario Amzel, Solomon H Snyder. Proc Natl Acad Sci U S A 2007
Asif K Mustafa, Manish Kumar, Balakrishnan Selvakumar, Gary P H Ho, Jeffrey T Ehmsen, Roxanne K Barrow, L Mario Amzel, Solomon H Snyder. Proc Natl Acad Sci U S A 2007
33
Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine.
Joari De Miranda, Rogerio Panizzutti, Veronika N Foltyn, Herman Wolosker. Proc Natl Acad Sci U S A 2002
Joari De Miranda, Rogerio Panizzutti, Veronika N Foltyn, Herman Wolosker. Proc Natl Acad Sci U S A 2002
33
Drug discovery targeting amino acid racemases.
Paola Conti, Lucia Tamborini, Andrea Pinto, Arnaud Blondel, Paola Minoprio, Andrea Mozzarelli, Carlo De Micheli. Chem Rev 2011
Paola Conti, Lucia Tamborini, Andrea Pinto, Arnaud Blondel, Paola Minoprio, Andrea Mozzarelli, Carlo De Micheli. Chem Rev 2011
28
Serine racemase: a key player in neuron activity and in neuropathologies.
Barbara Campanini, Francesca Spyrakis, Alessio Peracchi, Andrea Mozzarelli. Front Biosci (Landmark Ed) 2013
Barbara Campanini, Francesca Spyrakis, Alessio Peracchi, Andrea Mozzarelli. Front Biosci (Landmark Ed) 2013
28
Modulation of D-serine levels via ubiquitin-dependent proteasomal degradation of serine racemase.
Elena Dumin, Inna Bendikov, Veronika N Foltyn, Yoshio Misumi, Yukio Ikehara, Elena Kartvelishvily, Herman Wolosker. J Biol Chem 2006
Elena Dumin, Inna Bendikov, Veronika N Foltyn, Yoshio Misumi, Yukio Ikehara, Elena Kartvelishvily, Herman Wolosker. J Biol Chem 2006
28
Direct calcium binding results in activation of brain serine racemase.
Silas P Cook, Ismael Galve-Roperh, Alvaro Martínez del Pozo, Ignacio Rodríguez-Crespo. J Biol Chem 2002
Silas P Cook, Ismael Galve-Roperh, Alvaro Martínez del Pozo, Ignacio Rodríguez-Crespo. J Biol Chem 2002
28
Regulation of human serine racemase activity and dynamics by halides, ATP and malonate.
Marialaura Marchetti, Stefano Bruno, Barbara Campanini, Stefano Bettati, Alessio Peracchi, Andrea Mozzarelli. Amino Acids 2015
Marialaura Marchetti, Stefano Bruno, Barbara Campanini, Stefano Bettati, Alessio Peracchi, Andrea Mozzarelli. Amino Acids 2015
28
Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries.
Seth M Dixon, Pu Li, Ruiwu Liu, Herman Wolosker, Kit S Lam, Mark J Kurth, Michael D Toney. J Med Chem 2006
Seth M Dixon, Pu Li, Ruiwu Liu, Herman Wolosker, Kit S Lam, Mark J Kurth, Michael D Toney. J Med Chem 2006
23
Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane.
Livia Balan, Veronika N Foltyn, Martin Zehl, Elena Dumin, Elena Dikopoltsev, Diana Knoh, Yusuke Ohno, Akio Kihara, Ole N Jensen, Inna S Radzishevsky,[...]. Proc Natl Acad Sci U S A 2009
Livia Balan, Veronika N Foltyn, Martin Zehl, Elena Dumin, Elena Dikopoltsev, Diana Knoh, Yusuke Ohno, Akio Kihara, Ole N Jensen, Inna S Radzishevsky,[...]. Proc Natl Acad Sci U S A 2009
23
Serine racemase binds to PICK1: potential relevance to schizophrenia.
K Fujii, K Maeda, T Hikida, A K Mustafa, R Balkissoon, J Xia, T Yamada, Y Ozeki, R Kawahara, M Okawa,[...]. Mol Psychiatry 2006
K Fujii, K Maeda, T Hikida, A K Mustafa, R Balkissoon, J Xia, T Yamada, Y Ozeki, R Kawahara, M Okawa,[...]. Mol Psychiatry 2006
23
Structure-function relationships in human D-amino acid oxidase.
Silvia Sacchi, Laura Caldinelli, Pamela Cappelletti, Loredano Pollegioni, Gianluca Molla. Amino Acids 2012
Silvia Sacchi, Laura Caldinelli, Pamela Cappelletti, Loredano Pollegioni, Gianluca Molla. Amino Acids 2012
23
Recombinant human serine racemase: enzymologic characterization and comparison with its mouse ortholog.
Hillary E Hoffman, Jana Jirásková, Marek Ingr, Marketa Zvelebil, Jan Konvalinka. Protein Expr Purif 2009
Hillary E Hoffman, Jana Jirásková, Marek Ingr, Marketa Zvelebil, Jan Konvalinka. Protein Expr Purif 2009
23
Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration.
Paul M Kim, Hiroyuki Aizawa, Peter S Kim, Alex S Huang, Sasrutha R Wickramasinghe, Amir H Kashani, Roxanne K Barrow, Richard L Huganir, Anirvan Ghosh, Solomon H Snyder. Proc Natl Acad Sci U S A 2005
Paul M Kim, Hiroyuki Aizawa, Peter S Kim, Alex S Huang, Sasrutha R Wickramasinghe, Amir H Kashani, Roxanne K Barrow, Richard L Huganir, Anirvan Ghosh, Solomon H Snyder. Proc Natl Acad Sci U S A 2005
23
Inhibition of human serine racemase, an emerging target for medicinal chemistry.
Jana Jirásková-Vaníčková, Rudiger Ettrich, Barbora Vorlová, Hillary E Hoffman, Martin Lepšík, Petr Jansa, Jan Konvalinka. Curr Drug Targets 2011
Jana Jirásková-Vaníčková, Rudiger Ettrich, Barbora Vorlová, Hillary E Hoffman, Martin Lepšík, Petr Jansa, Jan Konvalinka. Curr Drug Targets 2011
23
Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion.
T M Ma, S Abazyan, B Abazyan, J Nomura, C Yang, S Seshadri, A Sawa, S H Snyder, M V Pletnikov. Mol Psychiatry 2013
T M Ma, S Abazyan, B Abazyan, J Nomura, C Yang, S Seshadri, A Sawa, S H Snyder, M V Pletnikov. Mol Psychiatry 2013
23
Purification of serine racemase: biosynthesis of the neuromodulator D-serine.
H Wolosker, K N Sheth, M Takahashi, J P Mothet, R O Brady, C D Ferris, S H Snyder. Proc Natl Acad Sci U S A 1999
H Wolosker, K N Sheth, M Takahashi, J P Mothet, R O Brady, C D Ferris, S H Snyder. Proc Natl Acad Sci U S A 1999
23
Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes.
Masataka Suzuki, Jumpei Sasabe, Yurika Miyoshi, Kanako Kuwasako, Yutaka Muto, Kenji Hamase, Masaaki Matsuoka, Nobuaki Imanishi, Sadakazu Aiso. Proc Natl Acad Sci U S A 2015
Masataka Suzuki, Jumpei Sasabe, Yurika Miyoshi, Kanako Kuwasako, Yutaka Muto, Kenji Hamase, Masaaki Matsuoka, Nobuaki Imanishi, Sadakazu Aiso. Proc Natl Acad Sci U S A 2015
23
Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form.
Stefano Bruno, Marilena Margiotta, Francesco Marchesani, Gianluca Paredi, Valentina Orlandi, Serena Faggiano, Luca Ronda, Barbara Campanini, Andrea Mozzarelli. Biochim Biophys Acta Proteins Proteom 2017
Stefano Bruno, Marilena Margiotta, Francesco Marchesani, Gianluca Paredi, Valentina Orlandi, Serena Faggiano, Luca Ronda, Barbara Campanini, Andrea Mozzarelli. Biochim Biophys Acta Proteins Proteom 2017
29
Cell selective conditional null mutations of serine racemase demonstrate a predominate localization in cortical glutamatergic neurons.
Michael A Benneyworth, Yan Li, Alo C Basu, Vadim Y Bolshakov, Joseph T Coyle. Cell Mol Neurobiol 2012
Michael A Benneyworth, Yan Li, Alo C Basu, Vadim Y Bolshakov, Joseph T Coyle. Cell Mol Neurobiol 2012
19
Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity.
Kvido Strísovský, Jana Jirásková, Adriana Mikulová, Lubomír Rulísek, Jan Konvalinka. Biochemistry 2005
Kvido Strísovský, Jana Jirásková, Adriana Mikulová, Lubomír Rulísek, Jan Konvalinka. Biochemistry 2005
19
Allosteric regulation of mouse brain serine racemase.
Amos Neidle, David S Dunlop. Neurochem Res 2002
Amos Neidle, David S Dunlop. Neurochem Res 2002
19
Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor.
Hillary E Hoffman, Jana Jirásková, Petr Cígler, Miloslav Sanda, Jan Schraml, Jan Konvalinka. J Med Chem 2009
Hillary E Hoffman, Jana Jirásková, Petr Cígler, Miloslav Sanda, Jan Schraml, Jan Konvalinka. J Med Chem 2009
19
Serine racemase is predominantly localized in neurons in mouse brain.
Kazushi Miya, Ran Inoue, Yoshimi Takata, Manabu Abe, Rie Natsume, Kenji Sakimura, Kazuhisa Hongou, Toshio Miyawaki, Hisashi Mori. J Comp Neurol 2008
Kazushi Miya, Ran Inoue, Yoshimi Takata, Manabu Abe, Rie Natsume, Kenji Sakimura, Kazuhisa Hongou, Toshio Miyawaki, Hisashi Mori. J Comp Neurol 2008
19
Neuron-derived D-serine release provides a novel means to activate N-methyl-D-aspartate receptors.
Elena Kartvelishvily, Maria Shleper, Livia Balan, Elena Dumin, Herman Wolosker. J Biol Chem 2006
Elena Kartvelishvily, Maria Shleper, Livia Balan, Elena Dumin, Herman Wolosker. J Biol Chem 2006
19
Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide.
Sheng-Zhou Wu, Angela M Bodles, Mandy M Porter, W Sue T Griffin, Anthony S Basile, Steven W Barger. J Neuroinflammation 2004
Sheng-Zhou Wu, Angela M Bodles, Mandy M Porter, W Sue T Griffin, Anthony S Basile, Steven W Barger. J Neuroinflammation 2004
19
D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis.
Jumpei Sasabe, Tomohiro Chiba, Marina Yamada, Koichi Okamoto, Ikuo Nishimoto, Masaaki Matsuoka, Sadakazu Aiso. EMBO J 2007
Jumpei Sasabe, Tomohiro Chiba, Marina Yamada, Koichi Okamoto, Ikuo Nishimoto, Masaaki Matsuoka, Sadakazu Aiso. EMBO J 2007
19
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives.
Stefano Bruno, Francesco Marchesani, Luca Dellafiora, Marilena Margiotta, Serena Faggiano, Barbara Campanini, Andrea Mozzarelli. Biochem J 2016
Stefano Bruno, Francesco Marchesani, Luca Dellafiora, Marilena Margiotta, Serena Faggiano, Barbara Campanini, Andrea Mozzarelli. Biochem J 2016
40
Human serine racemase is nitrosylated at multiple sites.
Francesco Marchesani, Stefano Bruno, Gianluca Paredi, Samanta Raboni, Barbara Campanini, Andrea Mozzarelli. Biochim Biophys Acta Proteins Proteom 2018
Francesco Marchesani, Stefano Bruno, Gianluca Paredi, Samanta Raboni, Barbara Campanini, Andrea Mozzarelli. Biochim Biophys Acta Proteins Proteom 2018
50
EphrinBs regulate D-serine synthesis and release in astrocytes.
Zhiye Zhuang, Bing Yang, Michelle H Theus, Justin T Sick, John R Bethea, Thomas J Sick, Daniel J Liebl. J Neurosci 2010
Zhiye Zhuang, Bing Yang, Michelle H Theus, Justin T Sick, John R Bethea, Thomas J Sick, Daniel J Liebl. J Neurosci 2010
14
Roles of quaternary structure and cysteine residues in the activity of human serine racemase.
Wei Wang, Steven W Barger. BMC Biochem 2011
Wei Wang, Steven W Barger. BMC Biochem 2011
30
Localization of serine racemase and its role in the skin.
Ran Inoue, Yoko Yoshihisa, Yosuke Tojo, Chieko Okamura, Yuzo Yoshida, Jiro Kishimoto, Xinghua Luan, Masahiko Watanabe, Mineyuki Mizuguchi, Yuko Nabeshima,[...]. J Invest Dermatol 2014
Ran Inoue, Yoko Yoshihisa, Yosuke Tojo, Chieko Okamura, Yuzo Yoshida, Jiro Kishimoto, Xinghua Luan, Masahiko Watanabe, Mineyuki Mizuguchi, Yuko Nabeshima,[...]. J Invest Dermatol 2014
15
Localization of D-serine and serine racemase in neurons and neuroglias in mouse brain.
Xiaohui Ding, Ning Ma, Masato Nagahama, Kumiko Yamada, Reiji Semba. Neurol Sci 2011
Xiaohui Ding, Ning Ma, Masato Nagahama, Kumiko Yamada, Reiji Semba. Neurol Sci 2011
14
In silico and pharmacological screenings identify novel serine racemase inhibitors.
Hisashi Mori, Ryogo Wada, Jie Li, Tetsuya Ishimoto, Mineyuki Mizuguchi, Takayuki Obita, Hiroaki Gouda, Shuichi Hirono, Naoki Toyooka. Bioorg Med Chem Lett 2014
Hisashi Mori, Ryogo Wada, Jie Li, Tetsuya Ishimoto, Mineyuki Mizuguchi, Takayuki Obita, Hiroaki Gouda, Shuichi Hirono, Naoki Toyooka. Bioorg Med Chem Lett 2014
23
Mouse brain serine racemase catalyzes specific elimination of L-serine to pyruvate.
Kvido Strísovský, Jana Jirásková, Cyril Barinka, Pavel Majer, Camilo Rojas, Barbara S Slusher, Jan Konvalinka. FEBS Lett 2003
Kvido Strísovský, Jana Jirásková, Cyril Barinka, Pavel Majer, Camilo Rojas, Barbara S Slusher, Jan Konvalinka. FEBS Lett 2003
14
Regulation of serine racemase activity by amino acids.
David S Dunlop, Amos Neidle. Brain Res Mol Brain Res 2005
David S Dunlop, Amos Neidle. Brain Res Mol Brain Res 2005
14
D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release.
M J Schell, M E Molliver, S H Snyder. Proc Natl Acad Sci U S A 1995
M J Schell, M E Molliver, S H Snyder. Proc Natl Acad Sci U S A 1995
14
D-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors.
Eric R Stevens, Manuel Esguerra, Paul M Kim, Eric A Newman, Solomon H Snyder, Kathleen R Zahs, Robert F Miller. Proc Natl Acad Sci U S A 2003
Eric R Stevens, Manuel Esguerra, Paul M Kim, Eric A Newman, Solomon H Snyder, Kathleen R Zahs, Robert F Miller. Proc Natl Acad Sci U S A 2003
14
Expanding the chemical space of human serine racemase inhibitors.
Luca Dellafiora, Marialaura Marchetti, Francesca Spyrakis, Valentina Orlandi, Barbara Campanini, Gabriele Cruciani, Pietro Cozzini, Andrea Mozzarelli. Bioorg Med Chem Lett 2015
Luca Dellafiora, Marialaura Marchetti, Francesca Spyrakis, Valentina Orlandi, Barbara Campanini, Gabriele Cruciani, Pietro Cozzini, Andrea Mozzarelli. Bioorg Med Chem Lett 2015
15
NMDA- and beta-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice.
Ran Inoue, Kenji Hashimoto, Tomomi Harai, Hisashi Mori. J Neurosci 2008
Ran Inoue, Kenji Hashimoto, Tomomi Harai, Hisashi Mori. J Neurosci 2008
14
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.
J P Mothet, A T Parent, H Wolosker, R O Brady, D J Linden, C D Ferris, M A Rogawski, S H Snyder. Proc Natl Acad Sci U S A 2000
J P Mothet, A T Parent, H Wolosker, R O Brady, D J Linden, C D Ferris, M A Rogawski, S H Snyder. Proc Natl Acad Sci U S A 2000
14
Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction.
Darrick T Balu, Yan Li, Matthew D Puhl, Michael A Benneyworth, Alo C Basu, Shunsuke Takagi, Vadim Y Bolshakov, Joseph T Coyle. Proc Natl Acad Sci U S A 2013
Darrick T Balu, Yan Li, Matthew D Puhl, Michael A Benneyworth, Alo C Basu, Shunsuke Takagi, Vadim Y Bolshakov, Joseph T Coyle. Proc Natl Acad Sci U S A 2013
14
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model.
Viviane Labrie, Ryutaro Fukumura, Anjali Rastogi, Laura J Fick, Wei Wang, Paul C Boutros, James L Kennedy, Mawahib O Semeralul, Frankie H Lee, Glen B Baker,[...]. Hum Mol Genet 2009
Viviane Labrie, Ryutaro Fukumura, Anjali Rastogi, Laura J Fick, Wei Wang, Paul C Boutros, James L Kennedy, Mawahib O Semeralul, Frankie H Lee, Glen B Baker,[...]. Hum Mol Genet 2009
14
Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.
Ting Martin Ma, Bindu D Paul, Chenglai Fu, Shaohui Hu, Heng Zhu, Seth Blackshaw, Herman Wolosker, Solomon H Snyder. J Biol Chem 2014
Ting Martin Ma, Bindu D Paul, Chenglai Fu, Shaohui Hu, Heng Zhu, Seth Blackshaw, Herman Wolosker, Solomon H Snyder. J Biol Chem 2014
14
Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition.
Asif K Mustafa, Damian B van Rossum, Randen L Patterson, David Maag, Jeffrey T Ehmsen, Sadia K Gazi, Anutosh Chakraborty, Roxanne K Barrow, L Mario Amzel, Solomon H Snyder. Proc Natl Acad Sci U S A 2009
Asif K Mustafa, Damian B van Rossum, Randen L Patterson, David Maag, Jeffrey T Ehmsen, Sadia K Gazi, Anutosh Chakraborty, Roxanne K Barrow, L Mario Amzel, Solomon H Snyder. Proc Natl Acad Sci U S A 2009
14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.