Aleksandra Sindic. ISRN Nephrol 2013
Times Cited: 18
Times Cited: 18
Times Cited
Times Co-cited
Similarity
Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase.
F K Hamra, L R Forte, S L Eber, N V Pidhorodeckyj, W J Krause, R H Freeman, D T Chin, J A Tompkins, K F Fok, C E Smith. Proc Natl Acad Sci U S A 1993
F K Hamra, L R Forte, S L Eber, N V Pidhorodeckyj, W J Krause, R H Freeman, D T Chin, J A Tompkins, K F Fok, C E Smith. Proc Natl Acad Sci U S A 1993
44
Guanylate cyclase-C receptor activation: unexpected biology.
Stuart M Brierley. Curr Opin Pharmacol 2012
Stuart M Brierley. Curr Opin Pharmacol 2012
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Guanylin: an endogenous activator of intestinal guanylate cyclase.
M G Currie, K F Fok, J Kato, R J Moore, F K Hamra, K L Duffin, C E Smith. Proc Natl Acad Sci U S A 1992
M G Currie, K F Fok, J Kato, R J Moore, F K Hamra, K L Duffin, C E Smith. Proc Natl Acad Sci U S A 1992
33
Plecanatide, an oral guanylate cyclase C agonist acting locally in the gastrointestinal tract, is safe and well-tolerated in single doses.
Kunwar Shailubhai, Stephen Comiskey, John A Foss, Rong Feng, Laura Barrow, Gail M Comer, Gary S Jacob. Dig Dis Sci 2013
Kunwar Shailubhai, Stephen Comiskey, John A Foss, Rong Feng, Laura Barrow, Gail M Comer, Gary S Jacob. Dig Dis Sci 2013
33
Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine.
M Field, L H Graf, W J Laird, P L Smith. Proc Natl Acad Sci U S A 1978
M Field, L H Graf, W J Laird, P L Smith. Proc Natl Acad Sci U S A 1978
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Guanylyl cyclase is a heat-stable enterotoxin receptor.
S Schulz, C K Green, P S Yuen, D L Garbers. Cell 1990
S Schulz, C K Green, P S Yuen, D L Garbers. Cell 1990
27
Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity.
F K Hamra, S L Eber, D T Chin, M G Currie, L R Forte. Proc Natl Acad Sci U S A 1997
F K Hamra, S L Eber, D T Chin, M G Currie, L R Forte. Proc Natl Acad Sci U S A 1997
27
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Joel Castro, Andrea M Harrington, Patrick A Hughes, Christopher M Martin, Pei Ge, Courtney M Shea, Hong Jin, Sarah Jacobson, Gerhard Hannig, Elizabeth Mann,[...]. Gastroenterology 2013
Joel Castro, Andrea M Harrington, Patrick A Hughes, Christopher M Martin, Pei Ge, Courtney M Shea, Hong Jin, Sarah Jacobson, Gerhard Hannig, Elizabeth Mann,[...]. Gastroenterology 2013
27
Guanylin regulatory peptides: structures, biological activities mediated by cyclic GMP and pathobiology.
L R Forte. Regul Pept 1999
L R Forte. Regul Pept 1999
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Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli.
J M Hughes, F Murad, B Chang, R L Guerrant. Nature 1978
J M Hughes, F Murad, B Chang, R L Guerrant. Nature 1978
22
Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Shalina Mahajan-Miklos, Christine M Pierce, Robert M Solinga, Li Jing Sun,[...]. Eur J Pharmacol 2010
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Shalina Mahajan-Miklos, Christine M Pierce, Robert M Solinga, Li Jing Sun,[...]. Eur J Pharmacol 2010
22
Guanylate cyclase-C/cGMP: an emerging pathway in the regulation of visceral pain.
Gerhard Hannig, Boris Tchernychev, Caroline B Kurtz, Alexander P Bryant, Mark G Currie, Inmaculada Silos-Santiago. Front Mol Neurosci 2014
Gerhard Hannig, Boris Tchernychev, Caroline B Kurtz, Alexander P Bryant, Mark G Currie, Inmaculada Silos-Santiago. Front Mol Neurosci 2014
22
Guanylate cyclase-C as a therapeutic target in gastrointestinal disorders.
Scott A Waldman, Michael Camilleri. Gut 2018
Scott A Waldman, Michael Camilleri. Gut 2018
22
The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis.
Najla Arshad, Sandhya S Visweswariah. FEBS Lett 2012
Najla Arshad, Sandhya S Visweswariah. FEBS Lett 2012
22
Chloride secretion in response to guanylin in colonic epithelial from normal and transgenic cystic fibrosis mice.
A W Cuthbert, M E Hickman, L J MacVinish, M J Evans, W H Colledge, R Ratcliff, P W Seale, P P Humphrey. Br J Pharmacol 1994
A W Cuthbert, M E Hickman, L J MacVinish, M J Evans, W H Colledge, R Ratcliff, P W Seale, P P Humphrey. Br J Pharmacol 1994
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Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism.
N J Skelton, K C Garcia, D V Goeddel, C Quan, J P Burnier. Biochemistry 1994
N J Skelton, K C Garcia, D V Goeddel, C Quan, J P Burnier. Biochemistry 1994
16
Precursor structure, expression, and tissue distribution of human guanylin.
F J de Sauvage, S Keshav, W J Kuang, N Gillett, W Henzel, D V Goeddel. Proc Natl Acad Sci U S A 1992
F J de Sauvage, S Keshav, W J Kuang, N Gillett, W Henzel, D V Goeddel. Proc Natl Acad Sci U S A 1992
16
High salt intake increases uroguanylin expression in mouse kidney.
R Potthast, E Ehler, L A Scheving, A Sindic, E Schlatter, M Kuhn. Endocrinology 2001
R Potthast, E Ehler, L A Scheving, A Sindic, E Schlatter, M Kuhn. Endocrinology 2001
16
Structure and function of the heat-stable enterotoxin receptor/guanylyl cyclase C.
Arie B Vaandrager. Mol Cell Biochem 2002
Arie B Vaandrager. Mol Cell Biochem 2002
16
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation.
A B Vaandrager, A Smolenski, B C Tilly, A B Houtsmuller, E M Ehlert, A G Bot, M Edixhoven, W E Boomaars, S M Lohmann, H R de Jonge. Proc Natl Acad Sci U S A 1998
A B Vaandrager, A Smolenski, B C Tilly, A B Houtsmuller, E M Ehlert, A G Bot, M Edixhoven, W E Boomaars, S M Lohmann, H R de Jonge. Proc Natl Acad Sci U S A 1998
16
Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.
William D Chey, Anthony J Lembo, Bernard J Lavins, Steven J Shiff, Caroline B Kurtz, Mark G Currie, James E MacDougall, Xinwei D Jia, James Z Shao, Donald A Fitch,[...]. Am J Gastroenterol 2012
William D Chey, Anthony J Lembo, Bernard J Lavins, Steven J Shiff, Caroline B Kurtz, Mark G Currie, James E MacDougall, Xinwei D Jia, James Z Shao, Donald A Fitch,[...]. Am J Gastroenterol 2012
16
A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation.
Satish Rao, Anthony J Lembo, Steven J Shiff, Bernard J Lavins, Mark G Currie, Xinwei D Jia, Kelvin Shi, James E MacDougall, James Z Shao, Paul Eng,[...]. Am J Gastroenterol 2012
Satish Rao, Anthony J Lembo, Steven J Shiff, Bernard J Lavins, Mark G Currie, Xinwei D Jia, Kelvin Shi, James E MacDougall, James Z Shao, Paul Eng,[...]. Am J Gastroenterol 2012
16
Characterization of human uroguanylin: a member of the guanylin peptide family.
T Kita, C E Smith, K F Fok, K L Duffin, W M Moore, P J Karabatsos, J F Kachur, F K Hamra, N V Pidhorodeckyj, L R Forte. Am J Physiol 1994
T Kita, C E Smith, K F Fok, K L Duffin, W M Moore, P J Karabatsos, J F Kachur, F K Hamra, N V Pidhorodeckyj, L R Forte. Am J Physiol 1994
16
Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor.
Stephen L Carrithers, Cobern E Ott, Michael J Hill, Brett R Johnson, Weiyan Cai, Jason J Chang, Rajesh G Shah, Congmei Sun, Elizabeth A Mann, Manasses C Fonteles,[...]. Kidney Int 2004
Stephen L Carrithers, Cobern E Ott, Michael J Hill, Brett R Johnson, Weiyan Cai, Jason J Chang, Rajesh G Shah, Congmei Sun, Elizabeth A Mann, Manasses C Fonteles,[...]. Kidney Int 2004
16
Activation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferents.
Bin Feng, Michael E Kiyatkin, Jun-Ho La, Pei Ge, Robert Solinga, Inmaculada Silos-Santiago, Gerald F Gebhart. J Neurosci 2013
Bin Feng, Michael E Kiyatkin, Jun-Ho La, Pei Ge, Robert Solinga, Inmaculada Silos-Santiago, Gerald F Gebhart. J Neurosci 2013
16
Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation.
Inmaculada Silos-Santiago, Gerhard Hannig, Helene Eutamene, Elena E Ustinova, Sylvie G Bernier, Pei Ge, Christopher Graul, Sarah Jacobson, Hong Jin, Elaine Liong,[...]. Pain 2013
Inmaculada Silos-Santiago, Gerhard Hannig, Helene Eutamene, Elena E Ustinova, Sylvie G Bernier, Pei Ge, Christopher Graul, Sarah Jacobson, Hong Jin, Elaine Liong,[...]. Pain 2013
16
Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Christine M Pierce, Robert M Solinga, Jenny V Tobin, Shalina Mahajan-Miklos,[...]. Life Sci 2010
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Christine M Pierce, Robert M Solinga, Jenny V Tobin, Shalina Mahajan-Miklos,[...]. Life Sci 2010
16
Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.
Kunwar Shailubhai, Vaseem Palejwala, Krishna Priya Arjunan, Sayali Saykhedkar, Bradley Nefsky, John A Foss, Stephen Comiskey, Gary S Jacob, Scott E Plevy. World J Gastrointest Pharmacol Ther 2015
Kunwar Shailubhai, Vaseem Palejwala, Krishna Priya Arjunan, Sayali Saykhedkar, Bradley Nefsky, John A Foss, Stephen Comiskey, Gary S Jacob, Scott E Plevy. World J Gastrointest Pharmacol Ther 2015
16
16
A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic Constipation.
Philip B Miner, William D Koltun, Gregory J Wiener, Marianela De La Portilla, Blas Prieto, Kunwar Shailubhai, Mary Beth Layton, Laura Barrow, Leslie Magnus, Patrick H Griffin. Am J Gastroenterol 2017
Philip B Miner, William D Koltun, Gregory J Wiener, Marianela De La Portilla, Blas Prieto, Kunwar Shailubhai, Mary Beth Layton, Laura Barrow, Leslie Magnus, Patrick H Griffin. Am J Gastroenterol 2017
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UniRef: comprehensive and non-redundant UniProt reference clusters.
Baris E Suzek, Hongzhan Huang, Peter McGarvey, Raja Mazumder, Cathy H Wu. Bioinformatics 2007
Baris E Suzek, Hongzhan Huang, Peter McGarvey, Raja Mazumder, Cathy H Wu. Bioinformatics 2007
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Discriminative modelling of context-specific amino acid substitution probabilities.
Christof Angermüller, Andreas Biegert, Johannes Söding. Bioinformatics 2012
Christof Angermüller, Andreas Biegert, Johannes Söding. Bioinformatics 2012
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Expression of guanylin is downregulated in mouse and human intestinal adenomas.
K A Steinbrecher, T M Tuohy, K Heppner Goss, M C Scott, D P Witte, J Groden, M B Cohen. Biochem Biophys Res Commun 2000
K A Steinbrecher, T M Tuohy, K Heppner Goss, M C Scott, D P Witte, J Groden, M B Cohen. Biochem Biophys Res Commun 2000
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Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP.
K Shailubhai, H H Yu, K Karunanandaa, J Y Wang, S L Eber, Y Wang, N S Joo, H D Kim, B W Miedema, S Z Abbas,[...]. Cancer Res 2000
K Shailubhai, H H Yu, K Karunanandaa, J Y Wang, S L Eber, Y Wang, N S Joo, H D Kim, B W Miedema, S Z Abbas,[...]. Cancer Res 2000
11
Molecular structure of the toxin domain of heat-stable enterotoxin produced by a pathogenic strain of Escherichia coli. A putative binding site for a binding protein on rat intestinal epithelial cell membranes.
H Ozaki, T Sato, H Kubota, Y Hata, Y Katsube, Y Shimonishi. J Biol Chem 1991
H Ozaki, T Sato, H Kubota, Y Hata, Y Katsube, Y Shimonishi. J Biol Chem 1991
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ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins.
Markus Wiederstein, Manfred J Sippl. Nucleic Acids Res 2007
Markus Wiederstein, Manfred J Sippl. Nucleic Acids Res 2007
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Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.
G M Pitari, M D Di Guglielmo, J Park, S Schulz, S A Waldman. Proc Natl Acad Sci U S A 2001
G M Pitari, M D Di Guglielmo, J Park, S Schulz, S A Waldman. Proc Natl Acad Sci U S A 2001
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Solution structure of human proguanylin: the role of a hormone prosequence.
Thomas Lauber, Philipp Neudecker, Paul Rösch, Ute C Marx. J Biol Chem 2003
Thomas Lauber, Philipp Neudecker, Paul Rösch, Ute C Marx. J Biol Chem 2003
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Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences.
Weizhong Li, Adam Godzik. Bioinformatics 2006
Weizhong Li, Adam Godzik. Bioinformatics 2006
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GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation.
Berk Hess, Carsten Kutzner, David van der Spoel, Erik Lindahl. J Chem Theory Comput 2008
Berk Hess, Carsten Kutzner, David van der Spoel, Erik Lindahl. J Chem Theory Comput 2008
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Use of long term molecular dynamics simulation in predicting cancer associated SNPs.
Ambuj Kumar, Rituraj Purohit. PLoS Comput Biol 2014
Ambuj Kumar, Rituraj Purohit. PLoS Comput Biol 2014
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Guanylin mRNA expression in human intestine and colorectal adenocarcinoma.
M B Cohen, J A Hawkins, D P Witte. Lab Invest 1998
M B Cohen, J A Hawkins, D P Witte. Lab Invest 1998
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Electrostatics of nanosystems: application to microtubules and the ribosome.
N A Baker, D Sept, S Joseph, M J Holst, J A McCammon. Proc Natl Acad Sci U S A 2001
N A Baker, D Sept, S Joseph, M J Holst, J A McCammon. Proc Natl Acad Sci U S A 2001
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Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain.
H Eutamene, S Bradesi, M Larauche, V Theodorou, C Beaufrand, G Ohning, J Fioramonti, M Cohen, A P Bryant, C Kurtz,[...]. Neurogastroenterol Motil 2010
H Eutamene, S Bradesi, M Larauche, V Theodorou, C Beaufrand, G Ohning, J Fioramonti, M Cohen, A P Bryant, C Kurtz,[...]. Neurogastroenterol Motil 2010
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Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis.
Rebecca M Lovell, Alexander C Ford. Clin Gastroenterol Hepatol 2012
Rebecca M Lovell, Alexander C Ford. Clin Gastroenterol Hepatol 2012
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Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.
Jieru E Lin, Michael Valentino, Glen Marszalowicz, Michael S Magee, Peng Li, Adam E Snook, Brian A Stoecker, Chang Chang, Scott A Waldman. Toxins (Basel) 2010
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Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis.
Alexander C Ford, Nicole C Suares. Gut 2011
Alexander C Ford, Nicole C Suares. Gut 2011
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Two randomized trials of linaclotide for chronic constipation.
Anthony J Lembo, Harvey A Schneier, Steven J Shiff, Caroline B Kurtz, James E MacDougall, Xinwei D Jia, James Z Shao, Bernard J Lavins, Mark G Currie, Donald A Fitch,[...]. N Engl J Med 2011
Anthony J Lembo, Harvey A Schneier, Steven J Shiff, Caroline B Kurtz, James E MacDougall, Xinwei D Jia, James Z Shao, Bernard J Lavins, Mark G Currie, Donald A Fitch,[...]. N Engl J Med 2011
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Epidemiology of constipation in North America: a systematic review.
Peter D R Higgins, John F Johanson. Am J Gastroenterol 2004
Peter D R Higgins, John F Johanson. Am J Gastroenterol 2004
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Uroguanylin regulates net fluid secretion via the NHE2 isoform of the Na/H+ exchanger in an intestinal cellular model.
Roxana Toriano, Marcelo Ozu, Maria T Politi, Ricardo A Dorr, Maria A Curto, Claudia Capurro. Cell Physiol Biochem 2011
Roxana Toriano, Marcelo Ozu, Maria T Politi, Ricardo A Dorr, Maria A Curto, Claudia Capurro. Cell Physiol Biochem 2011
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.