G Saretzki. Curr Pharm Des 2014
Times Cited: 77
Times Cited: 77
Times Cited
Times Co-cited
Similarity
Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells.
Z Liu, Q Li, K Li, L Chen, W Li, M Hou, T Liu, J Yang, C Lindvall, M Björkholm,[...]. Oncogene 2013
Z Liu, Q Li, K Li, L Chen, W Li, M Hou, T Liu, J Yang, C Lindvall, M Björkholm,[...]. Oncogene 2013
23
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
23
Telomerase modulates Wnt signalling by association with target gene chromatin.
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
22
Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NF-κB-dependent transcription.
Deqiang Ding, Peng Xi, Junzhi Zhou, Miao Wang, Yu-Sheng Cong. FASEB J 2013
Deqiang Ding, Peng Xi, Junzhi Zhou, Miao Wang, Yu-Sheng Cong. FASEB J 2013
22
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
20
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis.
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
20
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
18
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins.
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
18
Telomerase directly regulates NF-κB-dependent transcription.
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
16
Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria.
Nilesh K Sharma, Aurelio Reyes, Paula Green, Matthieu J Caron, Marcelo G Bonini, Donna M Gordon, Ian J Holt, Janine Hertzog Santos. Nucleic Acids Res 2012
Nilesh K Sharma, Aurelio Reyes, Paula Green, Matthieu J Caron, Marcelo G Bonini, Donna M Gordon, Ian J Holt, Janine Hertzog Santos. Nucleic Acids Res 2012
15
The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.
Alison Spilsbury, Satomi Miwa, Johannes Attems, Gabriele Saretzki. J Neurosci 2015
Alison Spilsbury, Satomi Miwa, Johannes Attems, Gabriele Saretzki. J Neurosci 2015
18
Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer.
Yong Zhang, LingLing Toh, Peishan Lau, Xueying Wang. J Biol Chem 2012
Yong Zhang, LingLing Toh, Peishan Lau, Xueying Wang. J Biol Chem 2012
15
Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.
Katrin Hoffmeyer, Angelo Raggioli, Stefan Rudloff, Roman Anton, Andreas Hierholzer, Ignacio Del Valle, Kerstin Hein, Riana Vogt, Rolf Kemler. Science 2012
Katrin Hoffmeyer, Angelo Raggioli, Stefan Rudloff, Roman Anton, Andreas Hierholzer, Ignacio Del Valle, Kerstin Hein, Riana Vogt, Rolf Kemler. Science 2012
15
Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
14
TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
14
Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
14
Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria.
Ilaria Chiodi, Chiara Mondello. Front Oncol 2012
Ilaria Chiodi, Chiara Mondello. Front Oncol 2012
17
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells.
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
14
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
14
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
12
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
12
The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis.
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
12
12
Regulation of the human catalytic subunit of telomerase (hTERT).
Michael Daniel, Gregory W Peek, Trygve O Tollefsbol. Gene 2012
Michael Daniel, Gregory W Peek, Trygve O Tollefsbol. Gene 2012
11
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA.
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
11
Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies.
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
11
11
Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
11
25
Cytoplasmic TERT Associates to RNA Granules in Fully Mature Neurons: Role in the Translational Control of the Cell Cycle Inhibitor p15INK4B.
Francesca Iannilli, Francesca Zalfa, Annette Gartner, Claudia Bagni, Carlos G Dotti. PLoS One 2013
Francesca Iannilli, Francesca Zalfa, Annette Gartner, Claudia Bagni, Carlos G Dotti. PLoS One 2013
29
Direct activation of TERT transcription by c-MYC.
K J Wu, C Grandori, M Amacker, N Simon-Vermot, A Polack, J Lingner, R Dalla-Favera. Nat Genet 1999
K J Wu, C Grandori, M Amacker, N Simon-Vermot, A Polack, J Lingner, R Dalla-Favera. Nat Genet 1999
10
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
10
Alternatively spliced telomerase reverse transcriptase variants lacking telomerase activity stimulate cell proliferation.
Radmila Hrdlicková, Jirí Nehyba, Henry R Bose. Mol Cell Biol 2012
Radmila Hrdlicková, Jirí Nehyba, Henry R Bose. Mol Cell Biol 2012
12
Telomerase reverse transcriptase regulates microRNAs.
Timo Lassmann, Yoshiko Maida, Yasuhiro Tomaru, Mami Yasukawa, Yoshinari Ando, Miki Kojima, Vivi Kasim, Christophe Simon, Carsten O Daub, Piero Carninci,[...]. Int J Mol Sci 2015
Timo Lassmann, Yoshiko Maida, Yasuhiro Tomaru, Mami Yasukawa, Yoshinari Ando, Miki Kojima, Vivi Kasim, Christophe Simon, Carsten O Daub, Piero Carninci,[...]. Int J Mol Sci 2015
57
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
10
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation.
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
9
Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.
G A Ulaner, J F Hu, T H Vu, L C Giudice, A R Hoffman. Cancer Res 1998
G A Ulaner, J F Hu, T H Vu, L C Giudice, A R Hoffman. Cancer Res 1998
9
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.
A Kilian, D D Bowtell, H E Abud, G R Hime, D J Venter, P K Keese, E L Duncan, R R Reddel, R A Jefferson. Hum Mol Genet 1997
A Kilian, D D Bowtell, H E Abud, G R Hime, D J Venter, P K Keese, E L Duncan, R R Reddel, R A Jefferson. Hum Mol Genet 1997
9
The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
9
The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter.
Y S Cong, J Wen, S Bacchetti. Hum Mol Genet 1999
Y S Cong, J Wen, S Bacchetti. Hum Mol Genet 1999
9
Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
9
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells.
M Takakura, S Kyo, T Kanaya, H Hirano, J Takeda, M Yutsudo, M Inoue. Cancer Res 1999
M Takakura, S Kyo, T Kanaya, H Hirano, J Takeda, M Yutsudo, M Inoue. Cancer Res 1999
9
Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria.
Satomi Miwa, Rafal Czapiewski, Tengfei Wan, Amy Bell, Kirsten N Hill, Thomas von Zglinicki, Gabriele Saretzki. Aging (Albany NY) 2016
Satomi Miwa, Rafal Czapiewski, Tengfei Wan, Amy Bell, Kirsten N Hill, Thomas von Zglinicki, Gabriele Saretzki. Aging (Albany NY) 2016
20
Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications.
Tiantian Liu, Xiaotian Yuan, Dawei Xu. Genes (Basel) 2016
Tiantian Liu, Xiaotian Yuan, Dawei Xu. Genes (Basel) 2016
12
WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERThigh Prostate Cancer Stem Cells.
Kai Zhang, Yanjing Guo, Xue Wang, Huifang Zhao, Zhongzhong Ji, Chaping Cheng, Li Li, Yuxiang Fang, Dawei Xu, Helen He Zhu,[...]. Cancer Res 2017
Kai Zhang, Yanjing Guo, Xue Wang, Huifang Zhao, Zhongzhong Ji, Chaping Cheng, Li Li, Yuxiang Fang, Dawei Xu, Helen He Zhu,[...]. Cancer Res 2017
10
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Carolyn D Hurst, Fiona M Platt, Margaret A Knowles. Eur Urol 2014
Carolyn D Hurst, Fiona M Platt, Margaret A Knowles. Eur Urol 2014
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.