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Times Cited: 73
Times Cited
Times Co-cited
Similarity
39
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Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease.
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Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
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Guohao Wang, Xudong Liu, Marta A Gaertig, Shihua Li, Xiao-Jiang Li. Proc Natl Acad Sci U S A 2016
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Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
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Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
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Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
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Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons.
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An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin.
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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
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Regional and cellular gene expression changes in human Huntington's disease brain.
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12
Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
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Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice.
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Selective roles of normal and mutant huntingtin in neural induction and early neurogenesis.
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Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.
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Spatial and temporal requirements for huntingtin (Htt) in neuronal migration and survival during brain development.
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Huntingtin functions as a scaffold for selective macroautophagy.
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Network organization of the huntingtin proteomic interactome in mammalian brain.
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Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis.
Paula Dietrich, Irudayam Maria Johnson, Shanta Alli, Ioannis Dragatsis. PLoS Genet 2017
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Huntington disease: natural history, biomarkers and prospects for therapeutics.
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Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.
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Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease.
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Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
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Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
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Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
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Measures of growth in children at risk for Huntington disease.
Jessica K Lee, Kathy Mathews, Bradley Schlaggar, Joel Perlmutter, Jane S Paulsen, Eric Epping, Leon Burmeister, Peg Nopoulos. Neurology 2012
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Molecular mechanisms and potential therapeutical targets in Huntington's disease.
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Huntington disease.
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Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington's Disease.
Amandine Virlogeux, Eve Moutaux, Wilhelm Christaller, Aurélie Genoux, Julie Bruyère, Elodie Fino, Benoit Charlot, Maxime Cazorla, Frédéric Saudou. Cell Rep 2018
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Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation.
Shagun R Mehta, Colton M Tom, Yizhou Wang, Catherine Bresee, David Rushton, Pranav P Mathkar, Jie Tang, Virginia B Mattis. Cell Rep 2018
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Loss-of-Huntingtin in Medial and Lateral Ganglionic Lineages Differentially Disrupts Regional Interneuron and Projection Neuron Subtypes and Promotes Huntington's Disease-Associated Behavioral, Cellular, and Pathological Hallmarks.
Mark F Mehler, Jenna R Petronglo, Eduardo E Arteaga-Bracho, Maria E Gulinello, Michael L Winchester, Nandini Pichamoorthy, Stephen K Young, Christopher D DeJesus, Hifza Ishtiaq, Solen Gokhan,[...]. J Neurosci 2019
Mark F Mehler, Jenna R Petronglo, Eduardo E Arteaga-Bracho, Maria E Gulinello, Michael L Winchester, Nandini Pichamoorthy, Stephen K Young, Christopher D DeJesus, Hifza Ishtiaq, Solen Gokhan,[...]. J Neurosci 2019
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Targeting Huntingtin Expression in Patients with Huntington's Disease.
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9
Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.
Caley J Burrus, Spencer U McKinstry, Namsoo Kim, M Ilcim Ozlu, Aditya V Santoki, Francia Y Fang, Annie Ma, Yonca B Karadeniz, Atesh K Worthington, Ioannis Dragatsis,[...]. Cell Rep 2020
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43
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.