Alberto L'Abbate, Gemma Macchia, Pietro D'Addabbo, Angelo Lonoce, Doron Tolomeo, Domenico Trombetta, Klaas Kok, Christoph Bartenhagen, Christopher W Whelan, Orazio Palumbo, Marco Severgnini, Ingrid Cifola, Martin Dugas, Massimo Carella, Gianluca De Bellis, Mariano Rocchi, Lucia Carbone, Clelia Tiziana Storlazzi. Nucleic Acids Res 2014
Times Cited: 66
Times Cited: 66
Times Cited
Times Co-cited
Similarity
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.
Kristen M Turner, Viraj Deshpande, Doruk Beyter, Tomoyuki Koga, Jessica Rusert, Catherine Lee, Bin Li, Karen Arden, Bing Ren, David A Nathanson,[...]. Nature 2017
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Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.
Clelia Tiziana Storlazzi, Angelo Lonoce, Maria C Guastadisegni, Domenico Trombetta, Pietro D'Addabbo, Giulia Daniele, Alberto L'Abbate, Gemma Macchia, Cecilia Surace, Klaas Kok,[...]. Genome Res 2010
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Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.
David A Nathanson, Beatrice Gini, Jack Mottahedeh, Koppany Visnyei, Tomoyuki Koga, German Gomez, Ascia Eskin, Kiwook Hwang, Jun Wang, Kenta Masui,[...]. Science 2014
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Circular ecDNA promotes accessible chromatin and high oncogene expression.
Sihan Wu, Kristen M Turner, Nam Nguyen, Ramya Raviram, Marcella Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li,[...]. Nature 2019
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Massive genomic rearrangement acquired in a single catastrophic event during cancer development.
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Double minute chromosomes can be produced from precursors derived from a chromosomal deletion.
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S M Carroll, M L DeRose, P Gaudray, C M Moore, D R Needham-Vandevanter, D D Von Hoff, G M Wahl. Mol Cell Biol 1988
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Extrachromosomal oncogene amplification in tumour pathogenesis and evolution.
Roel G W Verhaak, Vineet Bafna, Paul S Mischel. Nat Rev Cancer 2019
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Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma.
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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.
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Discoveries of Extrachromosomal Circles of DNA in Normal and Tumor Cells.
Teressa Paulsen, Pankaj Kumar, M Murat Koseoglu, Anindya Dutta. Trends Genet 2018
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Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Richard P Koche, Elias Rodriguez-Fos, Konstantin Helmsauer, Martin Burkert, Ian C MacArthur, Jesper Maag, Rocio Chamorro, Natalia Munoz-Perez, Montserrat Puiggròs, Heathcliff Dorado Garcia,[...]. Nat Genet 2020
Richard P Koche, Elias Rodriguez-Fos, Konstantin Helmsauer, Martin Burkert, Ian C MacArthur, Jesper Maag, Rocio Chamorro, Natalia Munoz-Perez, Montserrat Puiggròs, Heathcliff Dorado Garcia,[...]. Nat Genet 2020
25
MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene.
Clelia Tiziana Storlazzi, Thoas Fioretos, Cecilia Surace, Angelo Lonoce, Angela Mastrorilli, Bodil Strömbeck, Pietro D'Addabbo, Francesco Iacovelli, Crescenzio Minervini, Anna Aventin,[...]. Hum Mol Genet 2006
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Chromothripsis from DNA damage in micronuclei.
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Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues.
Yoshiyuki Shibata, Pankaj Kumar, Ryan Layer, Smaranda Willcox, Jeffrey R Gagan, Jack D Griffith, Anindya Dutta. Science 2012
Yoshiyuki Shibata, Pankaj Kumar, Ryan Layer, Smaranda Willcox, Jeffrey R Gagan, Jack D Griffith, Anindya Dutta. Science 2012
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MINUTE CHROMATIN BODIES IN MALIGNANT TUMOURS OF CHILDHOOD.
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Transposition and amplification of oncogene-related sequences in human neuroblastomas.
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Criteria for inference of chromothripsis in cancer genomes.
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Circular DNA elements of chromosomal origin are common in healthy human somatic tissue.
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21
Exploring the landscape of focal amplifications in cancer using AmpliconArchitect.
Viraj Deshpande, Jens Luebeck, Nam-Phuong D Nguyen, Mehrdad Bakhtiari, Kristen M Turner, Richard Schwab, Hannah Carter, Paul S Mischel, Vineet Bafna. Nat Commun 2019
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Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas.
Nicolas Vogt, Sandrine-Hélène Lefèvre, Françoise Apiou, Anne-Marie Dutrillaux, Andrej Cör, Pascal Leuraud, Marie-France Poupon, Bernard Dutrillaux, Michelle Debatisse, Bernard Malfoy. Proc Natl Acad Sci U S A 2004
Nicolas Vogt, Sandrine-Hélène Lefèvre, Françoise Apiou, Anne-Marie Dutrillaux, Andrej Cör, Pascal Leuraud, Marie-France Poupon, Bernard Dutrillaux, Michelle Debatisse, Bernard Malfoy. Proc Natl Acad Sci U S A 2004
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Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their tumorigenicity.
D D Von Hoff, J R McGill, B J Forseth, K K Davidson, T P Bradley, D R Van Devanter, G M Wahl. Proc Natl Acad Sci U S A 1992
D D Von Hoff, J R McGill, B J Forseth, K K Davidson, T P Bradley, D R Van Devanter, G M Wahl. Proc Natl Acad Sci U S A 1992
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Extrachromosomal double minutes and chromosomal homogeneously staining regions as probes for chromosome research.
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Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Hoon Kim, Nam-Phuong Nguyen, Kristen Turner, Sihan Wu, Amit D Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi,[...]. Nat Genet 2020
Hoon Kim, Nam-Phuong Nguyen, Kristen Turner, Sihan Wu, Amit D Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi,[...]. Nat Genet 2020
19
Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons.
J Zachary Sanborn, Sofie R Salama, Mia Grifford, Cameron W Brennan, Tom Mikkelsen, Suresh Jhanwar, Sol Katzman, Lynda Chin, David Haussler. Cancer Res 2013
J Zachary Sanborn, Sofie R Salama, Mia Grifford, Cameron W Brennan, Tom Mikkelsen, Suresh Jhanwar, Sol Katzman, Lynda Chin, David Haussler. Cancer Res 2013
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Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.
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18
Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation.
Pankaj Kumar, Laura W Dillon, Yoshiyuki Shibata, Amir A Jazaeri, David R Jones, Anindya Dutta. Mol Cancer Res 2017
Pankaj Kumar, Laura W Dillon, Yoshiyuki Shibata, Amir A Jazaeri, David R Jones, Anindya Dutta. Mol Cancer Res 2017
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Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.
Nicolas Vogt, Anne Gibaud, Frédéric Lemoine, Pierre de la Grange, Michelle Debatisse, Bernard Malfoy. Nucleic Acids Res 2014
Nicolas Vogt, Anne Gibaud, Frédéric Lemoine, Pierre de la Grange, Michelle Debatisse, Bernard Malfoy. Nucleic Acids Res 2014
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Nonselective DNA damage induced by a replication inhibitor results in the selective elimination of extrachromosomal double minutes from human cancer cells.
Noriaki Shimizu, Naomi Misaka, Koh-ichi Utani. Genes Chromosomes Cancer 2007
Noriaki Shimizu, Naomi Misaka, Koh-ichi Utani. Genes Chromosomes Cancer 2007
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Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase.
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Induction of differentiation in HL60 cells by the reduction of extrachromosomally amplified c-myc.
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S G Eckhardt, A Dai, K K Davidson, B J Forseth, G M Wahl, D D Von Hoff. Proc Natl Acad Sci U S A 1994
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Inhibiting homologous recombination decreases extrachromosomal amplification but has no effect on intrachromosomal amplification in methotrexate-resistant colon cancer cells.
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Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.
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In vivo elimination of acentric double minutes containing amplified MYCN from neuroblastoma tumor cells through the formation of micronuclei.
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Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes.
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Extrachromosomal driver mutations in glioblastoma and low-grade glioma.
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The architecture and evolution of cancer neochromosomes.
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Frequency of double minute chromosomes and combined cytogenetic abnormalities and their characteristics.
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Extrachromosomal circular DNA is common in yeast.
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Hydroxyurea accelerates loss of extrachromosomally amplified genes from tumor cells.
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Structure and evolution of double minutes in diagnosis and relapse brain tumors.
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Double-strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation.
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Extrachromosomal DNA-relieving heredity constraints, accelerating tumour evolution.
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PVT1 dependence in cancer with MYC copy-number increase.
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When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation.
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Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks.
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Effects of hydroxyurea on extrachromosomal DNA in patients with advanced ovarian carcinomas.
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Massa J Shoura, Idan Gabdank, Loren Hansen, Jason Merker, Jason Gotlib, Stephen D Levene, Andrew Z Fire. G3 (Bethesda) 2017
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Mitotic segregation of viral and cellular acentric extrachromosomal molecules by chromosome tethering.
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Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Konstantin Helmsauer, Maria E Valieva, Salaheddine Ali, Rocío Chamorro González, Robert Schöpflin, Claudia Röefzaad, Yi Bei, Heathcliff Dorado Garcia, Elias Rodriguez-Fos, Montserrat Puiggròs,[...]. Nat Commun 2020
Konstantin Helmsauer, Maria E Valieva, Salaheddine Ali, Rocío Chamorro González, Robert Schöpflin, Claudia Röefzaad, Yi Bei, Heathcliff Dorado Garcia, Elias Rodriguez-Fos, Montserrat Puiggròs,[...]. Nat Commun 2020
22
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.